Tamarixetin

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  • Identifiers

    CAS number
    603-61-2

    Molecular formula
    C16H12O7

    SMILES
    COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Phenolic 58.3%
    Odorless 53.88%
    Burnt 38.22%
    Smoky 29.18%
    Vanilla 27.15%
    Spicy 26.49%
    Medicinal 24.14%
    Balsamic 23.73%
    Savory 20.86%
    Dry 20.53%

     

    Flavor
    Bitter 91.3%
    Odorless 24.78%
    Bland 22.8%
    Sweet-like 21.83%
    Eugenol 21.34%
    Parsley 20.81%
    Cedarleaf 20.68%
    Lovage 19.97%
    Flat 19.96%
    Very strong 19.93%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.9

    pKa est.
    10.38 (weak base)

    Molecular weight
    316.26 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1069°C

    Flash point

    • 243.38 ˚C est.

  • Synonyms

    • Tamarixetin
    • 603-61-2
    • 4'-Methoxyquercetin
    • 4'-O-Methylquercetin
    • Quercetin 4'-methyl ether
    • 3,3',5,7-Tetrahydroxy-4'-methoxyflavone
    • 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one
    • 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-
    • 73WRA8Z8M8
    • 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone
    • 4'-Methoxy-3,3',5,7-tetrahydroxyflavone
    • CHEBI:67492
    • DTXSID00209056
    • RefChem:51404
    • DTXCID20131547
    • 210-050-7
    • 4'-O-Methyl Quercetin
    • 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one
    • MFCD00017308
    • 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
    • CHEMBL226034
    • 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxy-phenyl)chromen-4-one
    • Quercetin-4'-methylether
    • Quercetin, 4'-methyl ether
    • UNII-73WRA8Z8M8
    • 3-O-rhamnopyranosyl-1-2-glucopyranoside
    • EINECS 210-050-7
    • 3-O-alpha-L-rhamnopyranosyl-1-2-beta-D-glucopyranoside
    • BRN 0324993
    • 4'-o-methyl-quercetin
    • Tamarixetin (Standard)
    • 4'-Methoxy-3,3',5,7-tetrahydroxy-flavone
    • Flavone, 3,3',5,7-tetrahydroxy-4'-methoxy-
    • SCHEMBL892776
    • orb1297592
    • SCHEMBL29750609
    • SCHEMBL30255798
    • HY-N1181R
    • HY-N1181
    • BDBM50325674
    • LMPK12110606
    • AKOS024287252
    • EBC-462108
    • FM25556
    • 4'-methoxy-3,5,7,3'-tetrahydroflavone
    • AC-34261
    • AS-78314
    • DB-053606
    • CS-0016472
    • NS00034341
    • 4 inverted exclamation marka-O-Methyl Quercetin
    • E80555
    • FLAVONE, 4'-METHOXY-3,3',5,7-TETRAHYDROXY-
    • Q15427839
    • 603-61-2

  • Applications

    Tamarixetin (CAS 603-61-2) is a natural flavonol with practical applications across several industries: it is used as an antioxidant and stabilizer in cosmetic and personal-care formulations; in polymer and coating technologies, it is investigated as a stabilizing antioxidant to improve oxidative durability and color retention; it serves as a useful intermediate or building block in organic synthesis for fine chemicals and pharmaceutical research; in pharmaceutical and nutraceutical development, it is evaluated as a bioactive flavonoid scaffold; and in analytical and research settings it is used as a reference standard in flavonoid studies.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.05
    methanol 1.29
    isopropanol 1.21
    water 0.0
    ethyl acetate 1.42
    n-propanol 2.32
    acetone 0.17
    n-butanol 2.18
    acetonitrile 0.12
    DMF 14.36
    toluene 0.03
    isobutanol 1.06
    1,4-dioxane 1.28
    methyl acetate 0.94
    THF 13.46
    2-butanone 2.35
    n-pentanol 0.89
    sec-butanol 2.98
    n-hexane 0.01
    ethylene glycol 1.38
    NMP 18.39
    cyclohexane 0.0
    DMSO 76.79
    n-butyl acetate 1.16
    n-octanol 0.67
    chloroform 0.01
    n-propyl acetate 0.77
    acetic acid 1.05
    dichloromethane 0.02
    cyclohexanone 2.31
    propylene glycol 2.25
    isopropyl acetate 0.88
    DMAc 23.94
    2-ethoxyethanol 8.82
    isopentanol 1.67
    n-heptane 0.02
    ethyl formate 0.55
    1,2-dichloroethane 0.06
    n-hexanol 0.82
    2-methoxyethanol 30.01
    isobutyl acetate 0.2
    tetrachloromethane 0.01
    n-pentyl acetate 0.86
    transcutol 16.45
    n-heptanol 0.8
    ethylbenzene 0.03
    MIBK 0.93
    2-propoxyethanol 11.67
    tert-butanol 1.56
    MTBE 0.73
    2-butoxyethanol 4.49
    propionic acid 1.48
    o-xylene 0.05
    formic acid 1.58
    diethyl ether 0.63
    m-xylene 0.03
    p-xylene 0.03
    chlorobenzene 0.01
    dimethyl carbonate 1.15
    n-octane 0.01
    formamide 3.74
    cyclopentanone 5.23
    2-pentanone 1.64
    anisole 0.32
    cyclopentyl methyl ether 1.95
    gamma-butyrolactone 6.67
    1-methoxy-2-propanol 24.99
    pyridine 0.67
    3-pentanone 1.08
    furfural 3.88
    n-dodecane 0.01
    diethylene glycol 10.96
    diisopropyl ether 0.12
    tert-amyl alcohol 3.3
    acetylacetone 1.49
    n-hexadecane 0.01
    acetophenone 0.52
    methyl propionate 2.95
    isopentyl acetate 0.96
    trichloroethylene 0.1
    n-nonanol 0.79
    cyclohexanol 1.13
    benzyl alcohol 0.46
    2-ethylhexanol 0.59
    isooctanol 0.65
    dipropyl ether 0.88
    1,2-dichlorobenzene 0.02
    ethyl lactate 1.82
    propylene carbonate 1.19
    n-methylformamide 4.51
    2-pentanol 1.52
    n-pentane 0.01
    1-propoxy-2-propanol 8.13
    1-methoxy-2-propyl acetate 4.01
    2-(2-methoxypropoxy) propanol 5.75
    mesitylene 0.02
    ε-caprolactone 3.3
    p-cymene 0.08
    epichlorohydrin 5.48
    1,1,1-trichloroethane 0.02
    2-aminoethanol 3.4
    morpholine-4-carbaldehyde 13.71
    sulfolane 26.56
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 3.72
    n-hexyl acetate 1.23
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 7.22
    sec-butyl acetate 0.57
    tert-butyl acetate 1.35
    decalin 0.01
    glycerin 10.66
    diglyme 13.35
    acrylic acid 1.31
    isopropyl myristate 0.48
    n-butyric acid 2.1
    acetyl acetate 0.29
    di(2-ethylhexyl) phthalate 0.58
    ethyl propionate 1.26
    nitromethane 2.72
    1,2-diethoxyethane 2.09
    benzonitrile 0.16
    trioctyl phosphate 0.54
    1-bromopropane 0.08
    gamma-valerolactone 12.75
    n-decanol 0.55
    triethyl phosphate 0.92
    4-methyl-2-pentanol 0.63
    propionitrile 0.49
    vinylene carbonate 0.65
    1,1,2-trichlorotrifluoroethane 7.36
    DMS 1.05
    cumene 0.03
    2-octanol 0.55
    2-hexanone 0.95
    octyl acetate 0.76
    limonene 0.16
    1,2-dimethoxyethane 10.2
    ethyl orthosilicate 0.78
    tributyl phosphate 0.6
    diacetone alcohol 7.25
    N,N-dimethylaniline 0.34
    acrylonitrile 0.76
    aniline 0.27
    1,3-propanediol 7.2
    bromobenzene 0.01
    dibromomethane 0.01
    1,1,2,2-tetrachloroethane 0.16
    2-methyl-cyclohexyl acetate 0.78
    tetrabutyl urea 1.17
    diisobutyl methanol 0.43
    2-phenylethanol 0.66
    styrene 0.02
    dioctyl adipate 0.97
    dimethyl sulfate 4.45
    ethyl butyrate 1.22
    methyl lactate 5.69
    butyl lactate 1.88
    diethyl carbonate 0.61
    propanediol butyl ether 3.92
    triethyl orthoformate 1.33
    p-tert-butyltoluene 0.09
    methyl 4-tert-butylbenzoate 1.68
    morpholine 6.48
    tert-butylamine 0.32
    n-dodecanol 0.34
    dimethoxymethane 8.92
    ethylene carbonate 0.52
    cyrene 5.33
    2-ethoxyethyl acetate 1.86
    2-ethylhexyl acetate 0.66
    1,2,4-trichlorobenzene 0.06
    4-methylpyridine 0.48
    dibutyl ether 0.62
    2,6-dimethyl-4-heptanol 0.43
    DEF 5.77
    dimethyl isosorbide 8.25
    tetrachloroethylene 0.08
    eugenol 2.13
    triacetin 1.68
    span 80 3.16
    1,4-butanediol 0.99
    1,1-dichloroethane 0.02
    2-methyl-1-pentanol 0.94
    methyl formate 1.44
    2-methyl-1-butanol 2.13
    n-decane 0.02
    butyronitrile 0.4
    3,7-dimethyl-1-octanol 0.57
    1-chlorooctane 0.11
    1-chlorotetradecane 0.04
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.01
    cyclooctane 0.0
    cyclopentanol 1.92
    tetrahydropyran 0.97
    tert-amyl methyl ether 1.57
    2,5,8-trioxanonane 9.26
    1-hexene 0.04
    2-isopropoxyethanol 3.89
    2,2,2-trifluoroethanol 0.51
    methyl butyrate 1.62

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction