Sylpin

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  • Identifiers

    CAS number
    65501-41-9

    Molecular formula
    C17H14O6

    SMILES
    CC1=CC(=C(C2=C1OC(=C(C2=O)OC)C3=CC=C(C=C3)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Phenolic 68.05%
    Burnt 45.11%
    Smoky 39.89%
    Spicy 37.81%
    Odorless 34.39%
    Medicinal 32.72%
    Vanilla 31.93%
    Woody 26.76%
    Balsamic 25.89%
    Dry 25.72%

     

    Flavor
    Bitter 90.55%
    Odorless 22.28%
    Eugenol 21.62%
    Bland 21.25%
    Sweet-like 21.03%
    Parsley 20.94%
    Cedarleaf 20.38%
    Very strong 20.21%
    Flat 20.16%
    Indole 19.92%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.2

    pKa est.
    10.25 (weak base)

    Molecular weight
    314.29 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1029°C

    Melting point expt.

    • 301 - 303 °C

    Flash point

    • 231.05 ˚C est.

  • Synonyms

    • Sylpin
    • 4',5,6-trihydroxy-3-methoxy-8-methylflavone
    • Silpin
    • CHEBI:175018
    • DTXSID101145941
    • LMPK12111616
    • 65501-41-9
    • 5,6-dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-8-methylchromen-4-one
    • 5,6-Dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-8-methyl-4H-1-benzopyran-4-one
    • 65501-41-9

  • Applications

    Sylpin (CAS 65501-41-9) is typically used as an intermediate in chemical synthesis and may function as a solvent in industrial applications; it is also employed as a processing aid and stabilizer in polymers/plastics, in coatings and inks, and in cleaning formulations, depending on formulation needs and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.84
    methanol 0.61
    isopropanol 1.02
    water 0.0
    ethyl acetate 1.11
    n-propanol 1.48
    acetone 1.47
    n-butanol 1.39
    acetonitrile 0.49
    DMF 8.0
    toluene 0.44
    isobutanol 1.1
    1,4-dioxane 4.69
    methyl acetate 1.49
    THF 27.54
    2-butanone 3.33
    n-pentanol 1.21
    sec-butanol 1.52
    n-hexane 0.01
    ethylene glycol 0.83
    NMP 8.26
    cyclohexane 0.03
    DMSO 18.79
    n-butyl acetate 1.37
    n-octanol 1.42
    chloroform 0.18
    n-propyl acetate 1.23
    acetic acid 2.07
    dichloromethane 0.33
    cyclohexanone 5.19
    propylene glycol 0.99
    isopropyl acetate 1.26
    DMAc 17.33
    2-ethoxyethanol 5.37
    isopentanol 1.72
    n-heptane 0.04
    ethyl formate 0.74
    1,2-dichloroethane 0.66
    n-hexanol 1.35
    2-methoxyethanol 11.56
    isobutyl acetate 0.94
    tetrachloromethane 0.03
    n-pentyl acetate 2.24
    transcutol 16.2
    n-heptanol 1.76
    ethylbenzene 0.38
    MIBK 1.84
    2-propoxyethanol 7.61
    tert-butanol 2.33
    MTBE 1.34
    2-butoxyethanol 6.21
    propionic acid 1.21
    o-xylene 0.47
    formic acid 1.24
    diethyl ether 0.87
    m-xylene 0.38
    p-xylene 0.47
    chlorobenzene 0.3
    dimethyl carbonate 1.72
    n-octane 0.04
    formamide 2.73
    cyclopentanone 8.59
    2-pentanone 2.01
    anisole 1.52
    cyclopentyl methyl ether 3.41
    gamma-butyrolactone 7.34
    1-methoxy-2-propanol 7.67
    pyridine 4.54
    3-pentanone 1.47
    furfural 6.16
    n-dodecane 0.06
    diethylene glycol 7.78
    diisopropyl ether 0.28
    tert-amyl alcohol 2.44
    acetylacetone 3.26
    n-hexadecane 0.07
    acetophenone 2.29
    methyl propionate 1.72
    isopentyl acetate 1.96
    trichloroethylene 1.33
    n-nonanol 1.77
    cyclohexanol 1.76
    benzyl alcohol 2.03
    2-ethylhexanol 1.18
    isooctanol 1.71
    dipropyl ether 1.15
    1,2-dichlorobenzene 0.43
    ethyl lactate 1.59
    propylene carbonate 1.89
    n-methylformamide 2.13
    2-pentanol 0.94
    n-pentane 0.01
    1-propoxy-2-propanol 5.01
    1-methoxy-2-propyl acetate 3.72
    2-(2-methoxypropoxy) propanol 6.59
    mesitylene 0.23
    ε-caprolactone 4.0
    p-cymene 0.59
    epichlorohydrin 9.44
    1,1,1-trichloroethane 0.2
    2-aminoethanol 1.59
    morpholine-4-carbaldehyde 10.87
    sulfolane 13.74
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 5.36
    n-hexyl acetate 2.73
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 8.89
    sec-butyl acetate 1.1
    tert-butyl acetate 2.38
    decalin 0.04
    glycerin 4.2
    diglyme 15.84
    acrylic acid 1.48
    isopropyl myristate 1.35
    n-butyric acid 1.66
    acetyl acetate 0.74
    di(2-ethylhexyl) phthalate 1.77
    ethyl propionate 1.34
    nitromethane 3.97
    1,2-diethoxyethane 3.89
    benzonitrile 1.3
    trioctyl phosphate 1.41
    1-bromopropane 0.31
    gamma-valerolactone 13.87
    n-decanol 1.32
    triethyl phosphate 1.28
    4-methyl-2-pentanol 0.92
    propionitrile 1.01
    vinylene carbonate 1.46
    1,1,2-trichlorotrifluoroethane 7.09
    DMS 2.47
    cumene 0.35
    2-octanol 1.25
    2-hexanone 2.04
    octyl acetate 1.71
    limonene 0.64
    1,2-dimethoxyethane 10.68
    ethyl orthosilicate 1.35
    tributyl phosphate 1.45
    diacetone alcohol 6.49
    N,N-dimethylaniline 1.44
    acrylonitrile 1.67
    aniline 1.46
    1,3-propanediol 3.38
    bromobenzene 0.22
    dibromomethane 0.16
    1,1,2,2-tetrachloroethane 1.34
    2-methyl-cyclohexyl acetate 1.82
    tetrabutyl urea 2.66
    diisobutyl methanol 0.96
    2-phenylethanol 2.79
    styrene 0.33
    dioctyl adipate 2.1
    dimethyl sulfate 3.34
    ethyl butyrate 1.27
    methyl lactate 2.6
    butyl lactate 2.58
    diethyl carbonate 0.93
    propanediol butyl ether 4.7
    triethyl orthoformate 1.72
    p-tert-butyltoluene 0.58
    methyl 4-tert-butylbenzoate 4.02
    morpholine 8.44
    tert-butylamine 0.76
    n-dodecanol 0.97
    dimethoxymethane 7.25
    ethylene carbonate 1.18
    cyrene 5.89
    2-ethoxyethyl acetate 4.17
    2-ethylhexyl acetate 1.4
    1,2,4-trichlorobenzene 0.74
    4-methylpyridine 2.68
    dibutyl ether 1.52
    2,6-dimethyl-4-heptanol 0.96
    DEF 3.47
    dimethyl isosorbide 10.36
    tetrachloroethylene 0.76
    eugenol 4.91
    triacetin 3.16
    span 80 4.43
    1,4-butanediol 0.88
    1,1-dichloroethane 0.2
    2-methyl-1-pentanol 1.7
    methyl formate 1.62
    2-methyl-1-butanol 1.63
    n-decane 0.09
    butyronitrile 0.83
    3,7-dimethyl-1-octanol 1.5
    1-chlorooctane 0.49
    1-chlorotetradecane 0.25
    n-nonane 0.06
    undecane 0.07
    tert-butylcyclohexane 0.04
    cyclooctane 0.01
    cyclopentanol 2.0
    tetrahydropyran 3.21
    tert-amyl methyl ether 1.65
    2,5,8-trioxanonane 11.69
    1-hexene 0.12
    2-isopropoxyethanol 3.85
    2,2,2-trifluoroethanol 0.81
    methyl butyrate 1.77

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction