Sulforhodamine G

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  • Identifiers

    CAS number
    5873-16-5

    Molecular formula
    C25H25N2NaO7S2

    SMILES
    CCNC1=CC2=C(C=C1C)C(=C3C=C(C(=[NH+]CC)C=C3O2)C)C4=C(C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 69.69%
    Savory 25.26%
    Cooked 23.84%
    Roasted 23.41%
    Meaty 22.62%
    Grape 19.61%
    Bitter 17.86%
    Burnt 16.68%
    Milky 16.48%
    Fatty 16.1%

     

    Flavor
    Bitter 87.69%
    Odorless 30.95%
    Bland 20.36%
    Nitrile 20.34%
    Very strong 18.68%
    Cedarleaf 18.63%
    Taco 18.43%
    Indole 18.22%
    Sweet-like 18.21%
    Lovage 18.21%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    6.46 (neutral)

    Molecular weight
    552.6 g/mol

    Flash point

    • 365.85 ˚C est.

  • Synonyms

    • Sulforhodamine G
    • Acid Rhodamine G
    • CHEBI:52275
    • Xanthylium, 9-(2,4-disulfophenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, inner salt, monosodium salt
    • Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, monosodium salt
    • sodium 4-[3,6-bis(ethylamino)-2,7-dimethylxanthenium-9-yl]benzene-1,3-disulfonate
    • Xanthylium, 9-(2,4-disulfophenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, inner salt, sodium salt (1:1)
    • sodium 4-(3,6-bis(ethylamino)-2,7-dimethylxanthenium-9-yl)benzene-1,3-disulfonate
    • RefChem:889702
    • 227-528-6
    • Acid red 50
    • 5873-16-5
    • sodium;4-[3-(ethylamino)-6-ethylazaniumylidene-2,7-dimethylxanthen-9-yl]benzene-1,3-disulfonate
    • EINECS 227-528-6
    • CI 45220
    • SCHEMBL340942
    • orb2565210
    • MSK2476
    • YEOUFHBJWTZWCZ-UHFFFAOYSA-M
    • DTXSID801014654
    • AKOS000283078
    • Xanthylium, 9-(2,4-disulfophenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, hydroxide, inner salt, monosodium salt
    • NS00013512
    • Q27123343
    • Sodium 4-[3,6-bis(ethylamino)-2,7-dimethylxanthen-10-ium-9-yl]benzene-1,3-disulfonate
    • 9-(2,4-Disulfophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, hydroxide, inner salt, monosodium salt
    • 5873-16-5

  • Applications

    Sulforhodamine G (CAS 5873-16-5) is a water soluble sulfonated rhodamine fluorophore used as a fluorescent dye and tracer in research and analytical applications. Typical applications include fluorescent labeling and imaging in life sciences such as cell labeling, protein and nucleic acid labeling; flow cytometry and fluorescence-based detection; fluorescence microscopy reagents for confocal and epifluorescence work; fluorescent probes and reagents in analytical assays; and as a fluorescent tracer in inks and coatings for tracking and quality control in manufacturing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.5
    methanol 10.27
    isopropanol 1.65
    water 0.14
    ethyl acetate 1.3
    n-propanol 2.43
    acetone 4.24
    n-butanol 1.24
    acetonitrile 1.69
    DMF 53.08
    toluene 0.13
    isobutanol 1.06
    1,4-dioxane 2.07
    methyl acetate 3.17
    THF 3.99
    2-butanone 3.95
    n-pentanol 0.73
    sec-butanol 1.19
    n-hexane 0.01
    ethylene glycol 5.9
    NMP 36.95
    cyclohexane 0.01
    DMSO 15.48
    n-butyl acetate 0.97
    n-octanol 0.28
    chloroform 2.32
    n-propyl acetate 1.09
    acetic acid 13.77
    dichloromethane 2.43
    cyclohexanone 3.3
    propylene glycol 6.97
    isopropyl acetate 0.73
    DMAc 47.04
    2-ethoxyethanol 6.51
    isopentanol 0.64
    n-heptane 0.01
    ethyl formate 2.65
    1,2-dichloroethane 1.38
    n-hexanol 0.47
    2-methoxyethanol 19.28
    isobutyl acetate 0.46
    tetrachloromethane 0.16
    n-pentyl acetate 1.07
    transcutol 6.43
    n-heptanol 0.51
    ethylbenzene 0.06
    MIBK 0.69
    2-propoxyethanol 6.61
    tert-butanol 0.76
    MTBE 0.3
    2-butoxyethanol 3.89
    propionic acid 6.36
    o-xylene 0.11
    formic acid 19.51
    diethyl ether 0.5
    m-xylene 0.08
    p-xylene 0.1
    chlorobenzene 0.27
    dimethyl carbonate 4.46
    n-octane 0.01
    formamide 23.96
    cyclopentanone 6.47
    2-pentanone 1.72
    anisole 0.32
    cyclopentyl methyl ether 0.55
    gamma-butyrolactone 9.6
    1-methoxy-2-propanol 10.68
    pyridine 2.81
    3-pentanone 1.55
    furfural 9.39
    n-dodecane 0.01
    diethylene glycol 10.04
    diisopropyl ether 0.07
    tert-amyl alcohol 0.72
    acetylacetone 2.98
    n-hexadecane 0.01
    acetophenone 0.99
    methyl propionate 3.05
    isopentyl acetate 0.68
    trichloroethylene 4.01
    n-nonanol 0.31
    cyclohexanol 0.53
    benzyl alcohol 1.03
    2-ethylhexanol 0.21
    isooctanol 0.32
    dipropyl ether 0.33
    1,2-dichlorobenzene 0.29
    ethyl lactate 2.6
    propylene carbonate 3.64
    n-methylformamide 21.25
    2-pentanol 0.48
    n-pentane 0.01
    1-propoxy-2-propanol 3.71
    1-methoxy-2-propyl acetate 2.32
    2-(2-methoxypropoxy) propanol 3.42
    mesitylene 0.04
    ε-caprolactone 3.19
    p-cymene 0.07
    epichlorohydrin 5.92
    1,1,1-trichloroethane 0.47
    2-aminoethanol 7.45
    morpholine-4-carbaldehyde 22.29
    sulfolane 15.92
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 1.05
    n-hexyl acetate 0.79
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 3.63
    sec-butyl acetate 0.46
    tert-butyl acetate 0.53
    decalin 0.01
    glycerin 18.33
    diglyme 6.38
    acrylic acid 10.24
    isopropyl myristate 0.25
    n-butyric acid 3.92
    acetyl acetate 1.24
    di(2-ethylhexyl) phthalate 0.8
    ethyl propionate 0.85
    nitromethane 21.71
    1,2-diethoxyethane 1.05
    benzonitrile 0.81
    trioctyl phosphate 0.49
    1-bromopropane 0.37
    gamma-valerolactone 17.47
    n-decanol 0.22
    triethyl phosphate 0.61
    4-methyl-2-pentanol 0.19
    propionitrile 1.42
    vinylene carbonate 4.76
    1,1,2-trichlorotrifluoroethane 16.77
    DMS 1.99
    cumene 0.05
    2-octanol 0.25
    2-hexanone 1.09
    octyl acetate 0.48
    limonene 0.1
    1,2-dimethoxyethane 5.66
    ethyl orthosilicate 0.48
    tributyl phosphate 0.52
    diacetone alcohol 2.4
    N,N-dimethylaniline 0.33
    acrylonitrile 3.64
    aniline 0.75
    1,3-propanediol 6.43
    bromobenzene 0.17
    dibromomethane 0.91
    1,1,2,2-tetrachloroethane 2.9
    2-methyl-cyclohexyl acetate 0.62
    tetrabutyl urea 1.05
    diisobutyl methanol 0.11
    2-phenylethanol 0.91
    styrene 0.08
    dioctyl adipate 0.7
    dimethyl sulfate 9.65
    ethyl butyrate 0.74
    methyl lactate 9.04
    butyl lactate 2.64
    diethyl carbonate 0.66
    propanediol butyl ether 3.5
    triethyl orthoformate 0.76
    p-tert-butyltoluene 0.06
    methyl 4-tert-butylbenzoate 1.8
    morpholine 4.15
    tert-butylamine 0.21
    n-dodecanol 0.14
    dimethoxymethane 11.29
    ethylene carbonate 2.66
    cyrene 6.05
    2-ethoxyethyl acetate 2.63
    2-ethylhexyl acetate 0.5
    1,2,4-trichlorobenzene 0.59
    4-methylpyridine 1.54
    dibutyl ether 0.17
    2,6-dimethyl-4-heptanol 0.11
    DEF 4.6
    dimethyl isosorbide 4.33
    tetrachloroethylene 1.78
    eugenol 2.83
    triacetin 2.39
    span 80 2.61
    1,4-butanediol 2.52
    1,1-dichloroethane 0.83
    2-methyl-1-pentanol 0.43
    methyl formate 13.62
    2-methyl-1-butanol 0.74
    n-decane 0.01
    butyronitrile 0.83
    3,7-dimethyl-1-octanol 0.19
    1-chlorooctane 0.07
    1-chlorotetradecane 0.03
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.0
    cyclooctane 0.0
    cyclopentanol 1.33
    tetrahydropyran 0.76
    tert-amyl methyl ether 0.29
    2,5,8-trioxanonane 4.4
    1-hexene 0.06
    2-isopropoxyethanol 2.63
    2,2,2-trifluoroethanol 7.68
    methyl butyrate 1.44

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction