Suberic acid

Overview IFRA Request a quote

  • Identifiers

    CAS number
    505-48-6

    Molecular formula
    C8H14O4

    SMILES
    C(CCCC(=O)O)CCC(=O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sour 52.82%
    Cheesy 44.42%
    Odorless 42.49%
    Fatty 38.39%
    Dairy 28.27%
    Milky 27.5%
    Buttery 26.08%
    Savory 25.94%
    Creamy 24.95%
    Sweaty 24.09%

     

    Flavor
    Odorless 54.62%
    Sour 53.03%
    Cheese 47.89%
    Sweat 41.2%
    Rancid 40.4%
    Fatty 37.16%
    Acidic 36.32%
    Cheesy 27.63%
    Mild 26.97%
    Waxy 25.87%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.0

    pKa est.
    6.28 (neutral)

    Molecular weight
    174.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 144 °C

    Boiling point

    • 345.50 °C. @ 760.00 mm Hg

    Flash point

    • 167.42 ˚C est.

    Solubility expt.

    • 11.9 mg/mL

  • Synonyms

    • Octanedioic acid
    • SUBERIC ACID
    • 505-48-6
    • Cork acid
    • 1,6-Hexanedicarboxylic acid
    • 1,8-Octanedioic acid
    • Hexamethylenedicarboxylic acid
    • 6U7Y4M9C1H
    • DTXSID8021644
    • NSC-25952
    • CHEBI:9300
    • DTXCID101644
    • RefChem:932329
    • 208-010-9
    • hydron;octanedioate
    • Octane-1,8-dioic acid
    • 1,6-Dicarboxyhexane
    • Octanedioc acid
    • MFCD00004428
    • NSC25952
    • Kork Acid
    • UNII-6U7Y4M9C1H
    • Korksaeure
    • Oktandisaeure
    • Suberinsaeure
    • Korksaure
    • 1,8-Octanedioate
    • EINECS 208-010-9
    • NSC 25952
    • Octane-1,8-dioate
    • Suberic acid, 98%
    • Octane-1,8-dioic aid
    • 1,6-Hexanedicarboxylate
    • Hexamethylenedicarboxylate
    • AI3-52672
    • Suberic acid (Standard)
    • bmse000378
    • SUBERIC ACID [MI]
    • SCHEMBL3301
    • Octanedioic acid Suberic acid
    • BIDD:ER0503
    • orb1302608
    • CHEMBL1162491
    • BB_NC-00423
    • HY-W015300R
    • NSC53777
    • STR03966
    • Tox21_200531
    • AC7522
    • BBL009289
    • EBC-03310
    • LMFA01170001
    • MSK2579-100M
    • NSC-53777
    • s6220
    • SBB060278
    • STK801855
    • AKOS000119018
    • MSK2579-1000M
    • CS-W016016
    • FS52487
    • HY-W015300
    • Suberic acid, purum, >=98.0% (T)
    • NCGC00164012-01
    • NCGC00164012-02
    • NCGC00164012-03
    • NCGC00258085-01
    • BP-27862
    • CAS-505-48-6
    • SY004501
    • DB-071218
    • NS00015186
    • O0023
    • ST50307924
    • EN300-19300
    • Suberic acid Solution in Methanol, 100ug/mL
    • C08278
    • S-9000
    • Suberic acid Solution in Methanol, 1000ug/mL
    • AB00376809-03
    • F079481
    • Q899074
    • 932D754A-EE85-46C7-A95B-A93A3DC1EC61
    • F1905-7049
    • Z104473456
    • 505-48-6

  • Applications

    Suberic acid (CAS 505-48-6) is primarily used as a difunctional carboxylic acid monomer in the production of aliphatic polyesters and polyamides, supporting biodegradable and high-performance resin systems. It also functions as a crosslinking agent or chain extender in coatings, adhesives, and sealants, improving film formation and network properties. As a building block in specialty polymer synthesis, it enables high-performance resins and bio-based derivatives, including esters and lactones derived from its diacid functionality. Additionally, it serves as an intermediate in organic synthesis to introduce flexible aliphatic segments into polymer backbones. Use may be subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 95.44
    methanol 147.27
    isopropanol 52.4
    water 2.02
    ethyl acetate 7.29
    n-propanol 50.78
    acetone 31.54
    n-butanol 34.19
    acetonitrile 3.5
    DMF 262.9
    toluene 1.5
    isobutanol 28.45
    1,4-dioxane 13.6
    methyl acetate 7.97
    THF 111.03
    2-butanone 16.74
    n-pentanol 20.88
    sec-butanol 29.86
    n-hexane 1.65
    ethylene glycol 58.54
    NMP 275.04
    cyclohexane 0.64
    DMSO 553.04
    n-butyl acetate 13.66
    n-octanol 9.56
    chloroform 3.69
    n-propyl acetate 8.35
    acetic acid 61.18
    dichloromethane 3.73
    cyclohexanone 38.49
    propylene glycol 76.23
    isopropyl acetate 8.15
    DMAc 188.03
    2-ethoxyethanol 62.16
    isopentanol 27.44
    n-heptane 0.8
    ethyl formate 11.95
    1,2-dichloroethane 5.83
    n-hexanol 18.59
    2-methoxyethanol 140.87
    isobutyl acetate 4.76
    tetrachloromethane 1.31
    n-pentyl acetate 9.27
    transcutol 149.87
    n-heptanol 9.66
    ethylbenzene 2.75
    MIBK 14.24
    2-propoxyethanol 55.48
    tert-butanol 65.31
    MTBE 11.59
    2-butoxyethanol 28.47
    propionic acid 46.04
    o-xylene 3.97
    formic acid 77.47
    diethyl ether 4.78
    m-xylene 3.08
    p-xylene 3.58
    chlorobenzene 2.55
    dimethyl carbonate 8.54
    n-octane 0.37
    formamide 101.36
    cyclopentanone 82.47
    2-pentanone 16.31
    anisole 8.92
    cyclopentyl methyl ether 26.49
    gamma-butyrolactone 92.42
    1-methoxy-2-propanol 93.81
    pyridine 11.54
    3-pentanone 9.56
    furfural 70.73
    n-dodecane 0.29
    diethylene glycol 65.73
    diisopropyl ether 2.97
    tert-amyl alcohol 46.24
    acetylacetone 24.23
    n-hexadecane 0.32
    acetophenone 16.3
    methyl propionate 12.24
    isopentyl acetate 16.08
    trichloroethylene 10.36
    n-nonanol 8.55
    cyclohexanol 21.23
    benzyl alcohol 15.25
    2-ethylhexanol 10.05
    isooctanol 7.95
    dipropyl ether 6.32
    1,2-dichlorobenzene 4.69
    ethyl lactate 15.82
    propylene carbonate 36.99
    n-methylformamide 83.2
    2-pentanol 16.96
    n-pentane 0.73
    1-propoxy-2-propanol 38.22
    1-methoxy-2-propyl acetate 23.38
    2-(2-methoxypropoxy) propanol 45.82
    mesitylene 3.1
    ε-caprolactone 42.76
    p-cymene 3.4
    epichlorohydrin 45.7
    1,1,1-trichloroethane 3.05
    2-aminoethanol 95.52
    morpholine-4-carbaldehyde 123.22
    sulfolane 270.1
    2,2,4-trimethylpentane 0.99
    2-methyltetrahydrofuran 39.34
    n-hexyl acetate 15.47
    isooctane 0.63
    2-(2-butoxyethoxy)ethanol 56.63
    sec-butyl acetate 6.08
    tert-butyl acetate 17.22
    decalin 1.14
    glycerin 120.1
    diglyme 78.11
    acrylic acid 46.71
    isopropyl myristate 5.82
    n-butyric acid 39.31
    acetyl acetate 6.5
    di(2-ethylhexyl) phthalate 12.25
    ethyl propionate 8.67
    nitromethane 57.04
    1,2-diethoxyethane 13.03
    benzonitrile 7.34
    trioctyl phosphate 8.55
    1-bromopropane 2.56
    gamma-valerolactone 106.1
    n-decanol 6.05
    triethyl phosphate 10.68
    4-methyl-2-pentanol 11.09
    propionitrile 4.9
    vinylene carbonate 24.91
    1,1,2-trichlorotrifluoroethane 69.52
    DMS 14.08
    cumene 3.35
    2-octanol 6.0
    2-hexanone 12.25
    octyl acetate 8.32
    limonene 4.94
    1,2-dimethoxyethane 60.95
    ethyl orthosilicate 9.64
    tributyl phosphate 10.78
    diacetone alcohol 51.86
    N,N-dimethylaniline 12.9
    acrylonitrile 8.67
    aniline 7.06
    1,3-propanediol 88.32
    bromobenzene 1.9
    dibromomethane 3.06
    1,1,2,2-tetrachloroethane 12.3
    2-methyl-cyclohexyl acetate 15.11
    tetrabutyl urea 17.9
    diisobutyl methanol 7.13
    2-phenylethanol 13.84
    styrene 2.55
    dioctyl adipate 13.29
    dimethyl sulfate 41.11
    ethyl butyrate 10.51
    methyl lactate 31.36
    butyl lactate 21.09
    diethyl carbonate 7.42
    propanediol butyl ether 49.69
    triethyl orthoformate 10.62
    p-tert-butyltoluene 3.56
    methyl 4-tert-butylbenzoate 27.13
    morpholine 40.07
    tert-butylamine 25.09
    n-dodecanol 4.17
    dimethoxymethane 44.97
    ethylene carbonate 17.38
    cyrene 51.58
    2-ethoxyethyl acetate 15.59
    2-ethylhexyl acetate 10.79
    1,2,4-trichlorobenzene 6.78
    4-methylpyridine 11.85
    dibutyl ether 5.6
    2,6-dimethyl-4-heptanol 7.13
    DEF 35.75
    dimethyl isosorbide 70.16
    tetrachloroethylene 9.88
    eugenol 29.14
    triacetin 21.85
    span 80 37.41
    1,4-butanediol 30.88
    1,1-dichloroethane 2.34
    2-methyl-1-pentanol 19.16
    methyl formate 33.72
    2-methyl-1-butanol 25.73
    n-decane 0.5
    butyronitrile 6.17
    3,7-dimethyl-1-octanol 10.18
    1-chlorooctane 2.44
    1-chlorotetradecane 1.03
    n-nonane 0.46
    undecane 0.37
    tert-butylcyclohexane 1.28
    cyclooctane 0.37
    cyclopentanol 44.45
    tetrahydropyran 11.7
    tert-amyl methyl ether 13.4
    2,5,8-trioxanonane 64.06
    1-hexene 4.43
    2-isopropoxyethanol 31.78
    2,2,2-trifluoroethanol 24.28
    methyl butyrate 14.77

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction