Strigol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    11017-56-4

    Molecular formula
    C19H22O6

    SMILES
    CC1=C[C@@H](OC1=O)O/C=C/2\[C@H]3CC4=C([C@H]3OC2=O)C(CC[C@@H]4O)(C)C

    Safety labels

  • Odor profile

    Fragrance
    Sweet 50.87%
    Spicy 33.63%
    Odorless 31.63%
    Mint 31.13%
    Herbal 28.25%
    Woody 26.39%
    Lactonic 25.83%
    Celery 25.34%
    Coumarinic 25.11%
    Coconut 24.94%

     

    Flavor
    Bitter 93.28%
    Bland 20.82%
    Cedarleaf 19.91%
    Lovage 19.59%
    Sweet-like 19.31%
    Parsley 18.92%
    Ripe apricot 18.74%
    Red fruit 18.44%
    Leaves 17.74%
    Basil 17.69%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.3

    pKa est.
    4.93 (weak acid)

    Molecular weight
    346.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1359°C

    Flash point

    • 242.78 ˚C est.

  • Synonyms

    • Strigol
    • (+)-strigol
    • 11017-56-4
    • CHEBI:9290
    • 7I81Q4NS29
    • DTXSID8074449
    • (3E,3aR,5S,8bS)-5-hydroxy-8,8-dimethyl-3-[[(2R)-4-methyl-5-oxo-2H-furan-2-yl]oxymethylidene]-3a,4,5,6,7,8b-hexahydroindeno[1,2-b]furan-2-one
    • (3E,3aR,5S,8bS)-5-hydroxy-8,8-dimethyl-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methylene)-3,3a,4,5,6,7,8,8b-octahydro-2H-indeno[1,2-b]furan-2-one
    • (3E,3aR,5S,8bS)-5-hydroxy-8,8-dimethyl-3-((((2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl)oxy)methylene)-3,3a,4,5,6,7,8,8b-octahydro-2H-indeno(1,2-b)furan-2-one
    • (3E,3aR,5S,8bS)-5-hydroxy-8,8-dimethyl-3-(((2R)-4-methyl-5-oxo-2H-furan-2-yl)oxymethylidene)-3a,4,5,6,7,8b-hexahydroindeno(1,2-b)furan-2-one
    • RefChem:186024
    • DTXCID5033171
    • 2H-indeno(1,2-b)furan-2-one, 3-(2R)-2,5-dihydro-4-methyl-5-oxo-
    • 2H-Indeno[1,2-b]furan-2-one,3-[[(2,5-dihydro-4-methyl-5-oxo-2-furanyl)oxy]methylene]-3,3a,4,5,6,7,8,8b-octahydro-5-hydroxy-8,8-dimethyl-, [3E(R*),3aa,5b,8ba]-
    • 51820-11-2
    • UNII-7I81Q4NS29
    • STRIGOL [MI]
    • C09190
    • SCHEMBL121895
    • CHEMBL2270918
    • BDBM50510028
    • MFCD27665492
    • Q27108346
    • 2H-INDENO(1,2-B)FURAN-2-ONE, 3-((((2R)-2,5-DIHYDRO-4-METHYL-5-OXO-
    • (3aR,5S,8bS,E)-5-Hydroxy-8,8-dimethyl-3-((((R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl)oxy)methylene)-3,3a,4,5,6,7,8,8b-octahydro-2H-indeno[1,2-b]furan-2-one
    • (3E,3aR,5S,8bS)-5-Hydroxy-8,8-dimethyl-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methylidene)-3,3a,4,5,6,7,8,8b-octahydro-2H-indeno[1,2-b]furan-2-one
    • (3E,3aR,5S,8bS)-5-hydroxy-8,8-dimethyl-3-[[(2R)-4-methyl-5-oxo-2H-furan-2-yl]oxymethylene]-3a,4,5,6,7,8b-hexahydroindeno[1,2-b]furan-2-one
    • 2-FURANYL)OXY)METHYLENE)-3,3A,4,5,6,7,8,8B-OCTAHYDRO-5-HYDROXY-8,8-DIMETHYL-, (3AR-(3E(R*),3A.ALPHA.,5.BETA.,8B.ALPHA.))-
    • 2H-Indeno(1,2-b)furan-2-one, 3-((((2R)-2,5-dihydro-4-methyl-5-oxo-2-furanyl)oxy)methylene)-3,3a,4,5,6,7,8,8b-octahydro-5-hydroxy-8,8-dimethyl-, (3E,3aR,5S,8bS)-
    • 2H-Indeno(1,2-b)furan-2-one, 3-(((2,5-dihydro-4-methyl-5-oxo-2-furanyl)oxy)methylene)-3,3a,4,5,7,8,8b-octahydro-5-hydroxy-8,8-dimethyl-, (3aR-(3E(R*),3aalpha,5beta,8balpha))-
    • rel-(3aR,5S,8bS,E)-5-Hydroxy-8,8-dimethyl-3-((((R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl)oxy)methylene)-3,3a,4,5,6,7,8,8b-octahydro-2H-indeno[1,2-b]furan-2-one
    • 11017-56-4

  • Applications

    Strigol (CAS 11017-56-4) is an organic compound typically used as an intermediate in organic synthesis. In practice, it may serve as a solvent or processing aid in coating, ink, and adhesive formulations; it may be evaluated as a plasticizer or additive in polymers to modify processability or material properties. Additionally, Strigol can be considered as a fragrance/odorant ingredient in perfumery and personal care applications, and may appear in cleaning and household formulations as a solvent or blending component. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.99
    methanol 18.09
    isopropanol 9.21
    water 0.03
    ethyl acetate 55.61
    n-propanol 12.17
    acetone 67.39
    n-butanol 13.41
    acetonitrile 33.16
    DMF 143.55
    toluene 13.86
    isobutanol 8.27
    1,4-dioxane 74.38
    methyl acetate 47.84
    THF 176.92
    2-butanone 58.22
    n-pentanol 10.15
    sec-butanol 6.71
    n-hexane 0.14
    ethylene glycol 3.72
    NMP 124.1
    cyclohexane 0.32
    DMSO 104.99
    n-butyl acetate 28.39
    n-octanol 5.74
    chloroform 197.94
    n-propyl acetate 33.55
    acetic acid 88.7
    dichloromethane 132.61
    cyclohexanone 82.13
    propylene glycol 4.67
    isopropyl acetate 36.11
    DMAc 165.6
    2-ethoxyethanol 50.92
    isopentanol 13.81
    n-heptane 0.2
    ethyl formate 30.59
    1,2-dichloroethane 55.41
    n-hexanol 10.64
    2-methoxyethanol 89.3
    isobutyl acetate 24.52
    tetrachloromethane 6.35
    n-pentyl acetate 22.8
    transcutol 112.15
    n-heptanol 9.05
    ethylbenzene 4.9
    MIBK 32.45
    2-propoxyethanol 77.79
    tert-butanol 11.08
    MTBE 8.1
    2-butoxyethanol 41.37
    propionic acid 29.46
    o-xylene 6.33
    formic acid 40.1
    diethyl ether 11.9
    m-xylene 8.45
    p-xylene 7.81
    chlorobenzene 27.98
    dimethyl carbonate 46.8
    n-octane 0.13
    formamide 67.35
    cyclopentanone 121.62
    2-pentanone 51.81
    anisole 23.02
    cyclopentyl methyl ether 31.07
    gamma-butyrolactone 145.96
    1-methoxy-2-propanol 70.67
    pyridine 81.76
    3-pentanone 33.72
    furfural 117.64
    n-dodecane 0.21
    diethylene glycol 56.77
    diisopropyl ether 3.46
    tert-amyl alcohol 7.59
    acetylacetone 85.01
    n-hexadecane 0.27
    acetophenone 40.31
    methyl propionate 52.95
    isopentyl acetate 29.45
    trichloroethylene 193.57
    n-nonanol 7.38
    cyclohexanol 11.86
    benzyl alcohol 29.25
    2-ethylhexanol 7.22
    isooctanol 8.56
    dipropyl ether 7.12
    1,2-dichlorobenzene 27.65
    ethyl lactate 27.99
    propylene carbonate 64.98
    n-methylformamide 65.91
    2-pentanol 7.15
    n-pentane 0.16
    1-propoxy-2-propanol 42.19
    1-methoxy-2-propyl acetate 57.95
    2-(2-methoxypropoxy) propanol 41.68
    mesitylene 4.2
    ε-caprolactone 83.34
    p-cymene 4.23
    epichlorohydrin 186.52
    1,1,1-trichloroethane 40.54
    2-aminoethanol 9.13
    morpholine-4-carbaldehyde 148.01
    sulfolane 136.84
    2,2,4-trimethylpentane 0.21
    2-methyltetrahydrofuran 46.44
    n-hexyl acetate 25.75
    isooctane 0.2
    2-(2-butoxyethoxy)ethanol 50.61
    sec-butyl acetate 23.44
    tert-butyl acetate 34.22
    decalin 0.37
    glycerin 18.17
    diglyme 99.59
    acrylic acid 36.22
    isopropyl myristate 10.64
    n-butyric acid 56.89
    acetyl acetate 53.04
    di(2-ethylhexyl) phthalate 17.89
    ethyl propionate 31.11
    nitromethane 171.23
    1,2-diethoxyethane 27.76
    benzonitrile 35.66
    trioctyl phosphate 11.24
    1-bromopropane 13.9
    gamma-valerolactone 205.97
    n-decanol 5.19
    triethyl phosphate 15.87
    4-methyl-2-pentanol 7.05
    propionitrile 29.42
    vinylene carbonate 73.51
    1,1,2-trichlorotrifluoroethane 112.37
    DMS 36.46
    cumene 3.61
    2-octanol 4.66
    2-hexanone 33.1
    octyl acetate 14.69
    limonene 4.72
    1,2-dimethoxyethane 78.17
    ethyl orthosilicate 13.91
    tributyl phosphate 12.79
    diacetone alcohol 52.01
    N,N-dimethylaniline 14.68
    acrylonitrile 53.02
    aniline 26.97
    1,3-propanediol 24.79
    bromobenzene 27.9
    dibromomethane 56.56
    1,1,2,2-tetrachloroethane 118.36
    2-methyl-cyclohexyl acetate 24.28
    tetrabutyl urea 18.92
    diisobutyl methanol 4.74
    2-phenylethanol 32.26
    styrene 6.62
    dioctyl adipate 20.77
    dimethyl sulfate 72.57
    ethyl butyrate 22.85
    methyl lactate 43.0
    butyl lactate 24.49
    diethyl carbonate 17.9
    propanediol butyl ether 25.74
    triethyl orthoformate 18.95
    p-tert-butyltoluene 3.97
    methyl 4-tert-butylbenzoate 36.34
    morpholine 86.16
    tert-butylamine 3.4
    n-dodecanol 3.61
    dimethoxymethane 109.88
    ethylene carbonate 58.87
    cyrene 57.95
    2-ethoxyethyl acetate 44.13
    2-ethylhexyl acetate 20.85
    1,2,4-trichlorobenzene 40.06
    4-methylpyridine 67.15
    dibutyl ether 6.0
    2,6-dimethyl-4-heptanol 4.74
    DEF 56.07
    dimethyl isosorbide 79.33
    tetrachloroethylene 60.46
    eugenol 40.75
    triacetin 42.86
    span 80 28.88
    1,4-butanediol 9.17
    1,1-dichloroethane 48.36
    2-methyl-1-pentanol 11.21
    methyl formate 50.96
    2-methyl-1-butanol 10.07
    n-decane 0.34
    butyronitrile 25.84
    3,7-dimethyl-1-octanol 7.58
    1-chlorooctane 2.81
    1-chlorotetradecane 1.26
    n-nonane 0.23
    undecane 0.26
    tert-butylcyclohexane 0.32
    cyclooctane 0.15
    cyclopentanol 15.68
    tetrahydropyran 32.65
    tert-amyl methyl ether 7.64
    2,5,8-trioxanonane 66.6
    1-hexene 1.19
    2-isopropoxyethanol 35.93
    2,2,2-trifluoroethanol 31.64
    methyl butyrate 40.87

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction