Stearylbetaine

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  • Identifiers

    CAS number
    820-66-6

    Molecular formula
    C22H45NO2

    SMILES
    CCCCCCCCCCCCCCCCCC[N+](C)(C)CC(=O)[O-]

    Safety labels

  • Odor profile

    Fragrance
    Waxy 73.21%
    Fatty 57.84%
    Oily 36.09%
    Odorless 28.67%
    Woody 23.5%
    Creamy 23.39%
    Animal 21.92%
    Sweet 21.81%
    Milky 20.55%
    Meaty 20.45%

     

    Flavor
    Bland 37.0%
    Mild 31.48%
    Waxy 25.59%
    Faint 24.98%
    Odorless 23.22%
    Slightly waxy 22.49%
    Delicate 22.21%
    Bay oil 20.6%
    Beer 19.81%
    Diterpene 19.66%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    9.4

    pKa est.
    4.35 (weak acid)

    Molecular weight
    355.6 g/mol

    Flash point

    • -34.29 ˚C est.

  • Synonyms

    • Stearyl betaine
    • stearylbetaine
    • N-Stearylbetaine
    • Lonzaine 18S
    • Stearyldimethylbetaine
    • Stearyl dimethyl glycine
    • (Carboxymethyl)octadecyldimethylammonium hydroxide inner salt
    • 0J4V7PZ3Q6
    • NSC 9859
    • NSC-9859
    • EINECS 212-470-6
    • NSC 36343
    • NSC-36343
    • 1-Octadecanaminium, N-(carboxymethyl)-N,N-dimethyl-, inner salt
    • N,N-Dimethyl-N-octadecylammonioacetic acid inner salt
    • DTXSID5061164
    • Ammonium, (carboxymethyl)dimethyloctadecyl-, hydroxide, inner salt
    • N-(Carboxymethyl)-N,N-dimethyl-1-octadecanaminium hydroxide, inner salt
    • 1-Octadecanaminium, N-(carboxymethyl)-N,N-dimethyl-, hydroxide, inner salt
    • RefChem:889190
    • STEARYL BETAINE [INCI]
    • DTXCID0048262
    • 1-Octadecanaminium, N-(carboxymethyl)-N,N-dimethyl-, hydroxide, inner salt (9CI)
    • 820-66-6
    • (Carboxylatomethyl)dimethyl(octadecyl)ammonium
    • Anfoterico SB
    • 2-[dimethyl(octadecyl)azaniumyl]acetate
    • 2-(dimethyl(octadecyl)ammonio)acetate
    • 1-Octadecanaminium,N-dimethyl-, hydroxide, inner salt
    • UNII-0J4V7PZ3Q6
    • orb1695155
    • SCHEMBL3858642
    • NSC9859
    • HVYJSOSGTDINLW-UHFFFAOYSA-N
    • NSC36343
    • [Dimethyl(octadecyl)azaniumyl]acetate
    • AKOS040754088
    • NS00014123
    • Q27236851
    • 820-66-6

  • Applications

    Stearylbetaine (CAS 820-66-6) is an amphoteric alkyl betaine surfactant used as a mild cleansing agent and conditioning component in cosmetics and personal care (shampoos, body washes), providing soft foam and good skin feel. It also acts as an emulsifier and stabilizer for emulsions in personal care and household cleaning formulations, helping to improve dispersion and product stability. In industrial manufacturing it is used as a surfactant and co-emulsifier to enhance wetting, emulsification, and stability in paints, coatings, and inks. It can serve as a processing aid or stabilizing additive in polymer and plastic formulations, aiding emulsions and compatibility with other ingredients. Additionally, it may function as a foam modifier or stabilizer in formulating cleaners and surface care products.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 48.94
    methanol 81.12
    isopropanol 36.11
    water 1.29
    ethyl acetate 82.42
    n-propanol 51.97
    acetone 72.23
    n-butanol 46.37
    acetonitrile 28.86
    DMF 126.87
    toluene 39.26
    isobutanol 44.67
    1,4-dioxane 119.69
    methyl acetate 71.42
    THF 253.89
    2-butanone 85.65
    n-pentanol 38.47
    sec-butanol 44.72
    n-hexane 10.11
    ethylene glycol 12.45
    NMP 393.47
    cyclohexane 42.79
    DMSO 176.18
    n-butyl acetate 102.42
    n-octanol 46.62
    chloroform 379.3
    n-propyl acetate 112.05
    acetic acid 149.43
    dichloromethane 351.41
    cyclohexanone 311.81
    propylene glycol 25.94
    isopropyl acetate 76.09
    DMAc 214.46
    2-ethoxyethanol 98.4
    isopentanol 48.57
    n-heptane 10.73
    ethyl formate 73.89
    1,2-dichloroethane 223.2
    n-hexanol 39.44
    2-methoxyethanol 118.79
    isobutyl acetate 82.09
    tetrachloromethane 109.82
    n-pentyl acetate 172.97
    transcutol 352.04
    n-heptanol 52.36
    ethylbenzene 32.12
    MIBK 71.42
    2-propoxyethanol 97.58
    tert-butanol 55.28
    MTBE 48.07
    2-butoxyethanol 139.67
    propionic acid 101.95
    o-xylene 47.4
    formic acid 67.58
    diethyl ether 41.55
    m-xylene 38.09
    p-xylene 47.6
    chlorobenzene 89.34
    dimethyl carbonate 38.73
    n-octane 6.77
    formamide 93.69
    cyclopentanone 291.53
    2-pentanone 79.69
    anisole 54.53
    cyclopentyl methyl ether 141.1
    gamma-butyrolactone 330.63
    1-methoxy-2-propanol 98.21
    pyridine 128.35
    3-pentanone 74.93
    furfural 252.12
    n-dodecane 3.47
    diethylene glycol 60.53
    diisopropyl ether 22.74
    tert-amyl alcohol 64.47
    acetylacetone 111.81
    n-hexadecane 4.12
    acetophenone 97.65
    methyl propionate 81.75
    isopentyl acetate 99.89
    trichloroethylene 405.86
    n-nonanol 47.6
    cyclohexanol 109.94
    benzyl alcohol 59.34
    2-ethylhexanol 42.83
    isooctanol 53.72
    dipropyl ether 56.33
    1,2-dichlorobenzene 120.61
    ethyl lactate 74.3
    propylene carbonate 207.33
    n-methylformamide 89.12
    2-pentanol 34.67
    n-pentane 7.63
    1-propoxy-2-propanol 99.29
    1-methoxy-2-propyl acetate 111.92
    2-(2-methoxypropoxy) propanol 102.57
    mesitylene 32.56
    ε-caprolactone 305.54
    p-cymene 35.61
    epichlorohydrin 296.54
    1,1,1-trichloroethane 227.86
    2-aminoethanol 37.93
    morpholine-4-carbaldehyde 233.72
    sulfolane 573.86
    2,2,4-trimethylpentane 9.77
    2-methyltetrahydrofuran 182.33
    n-hexyl acetate 145.66
    isooctane 4.88
    2-(2-butoxyethoxy)ethanol 143.76
    sec-butyl acetate 80.69
    tert-butyl acetate 101.82
    decalin 17.19
    glycerin 50.0
    diglyme 277.25
    acrylic acid 85.93
    isopropyl myristate 44.58
    n-butyric acid 157.51
    acetyl acetate 73.4
    di(2-ethylhexyl) phthalate 55.76
    ethyl propionate 87.54
    nitromethane 164.17
    1,2-diethoxyethane 101.87
    benzonitrile 67.76
    trioctyl phosphate 43.33
    1-bromopropane 96.69
    gamma-valerolactone 396.8
    n-decanol 30.69
    triethyl phosphate 69.78
    4-methyl-2-pentanol 29.08
    propionitrile 35.55
    vinylene carbonate 172.6
    1,1,2-trichlorotrifluoroethane 312.09
    DMS 95.96
    cumene 30.35
    2-octanol 42.2
    2-hexanone 82.74
    octyl acetate 62.29
    limonene 55.4
    1,2-dimethoxyethane 144.58
    ethyl orthosilicate 69.74
    tributyl phosphate 53.55
    diacetone alcohol 119.72
    N,N-dimethylaniline 50.74
    acrylonitrile 46.63
    aniline 61.09
    1,3-propanediol 55.42
    bromobenzene 88.84
    dibromomethane 226.09
    1,1,2,2-tetrachloroethane 415.3
    2-methyl-cyclohexyl acetate 111.5
    tetrabutyl urea 72.24
    diisobutyl methanol 30.62
    2-phenylethanol 59.98
    styrene 33.15
    dioctyl adipate 85.96
    dimethyl sulfate 100.71
    ethyl butyrate 98.71
    methyl lactate 62.7
    butyl lactate 145.69
    diethyl carbonate 65.18
    propanediol butyl ether 109.89
    triethyl orthoformate 94.23
    p-tert-butyltoluene 33.11
    methyl 4-tert-butylbenzoate 137.19
    morpholine 174.16
    tert-butylamine 36.85
    n-dodecanol 20.54
    dimethoxymethane 78.72
    ethylene carbonate 156.3
    cyrene 132.65
    2-ethoxyethyl acetate 176.22
    2-ethylhexyl acetate 94.99
    1,2,4-trichlorobenzene 149.1
    4-methylpyridine 101.24
    dibutyl ether 55.07
    2,6-dimethyl-4-heptanol 30.62
    DEF 117.22
    dimethyl isosorbide 207.99
    tetrachloroethylene 322.7
    eugenol 117.43
    triacetin 184.09
    span 80 112.37
    1,4-butanediol 25.67
    1,1-dichloroethane 157.02
    2-methyl-1-pentanol 43.07
    methyl formate 65.76
    2-methyl-1-butanol 50.12
    n-decane 7.87
    butyronitrile 40.01
    3,7-dimethyl-1-octanol 44.72
    1-chlorooctane 41.27
    1-chlorotetradecane 12.34
    n-nonane 7.68
    undecane 4.93
    tert-butylcyclohexane 13.01
    cyclooctane 12.39
    cyclopentanol 113.02
    tetrahydropyran 153.35
    tert-amyl methyl ether 55.8
    2,5,8-trioxanonane 166.56
    1-hexene 24.71
    2-isopropoxyethanol 77.15
    2,2,2-trifluoroethanol 97.54
    methyl butyrate 126.86

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction