Stearyl tyrosine

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  • Identifiers

    CAS number
    73393-27-8

    Molecular formula
    C27H47NO3

    SMILES
    CCCCCCCCCCCCCCCCCCOC(=O)[C@H](CC1=CC=C(C=C1)O)N

    Safety labels

  • Odor profile

    Fragrance
    Waxy 56.17%
    Fatty 38.35%
    Oily 35.65%
    Odorless 34.36%
    Balsamic 29.86%
    Sweet 26.39%
    Floral 26.26%
    Fresh 25.39%
    Animal 24.44%
    Citrus 23.36%

     

    Flavor
    Bland 35.99%
    Mild 35.41%
    Odorless 29.77%
    Faint 26.29%
    Waxy 24.56%
    Slightly waxy 21.69%
    Fatty 20.77%
    Delicate 20.76%
    Oily 20.69%
    Bay oil 20.1%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    9.7

    pKa est.
    8.57 (weak base)

    Molecular weight
    433.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    659°C

    Flash point

    • 228.43 ˚C est.

  • Synonyms

    • 73393-27-8
    • Stearyl tyrosine
    • Tyrosine octadecyl ester
    • octadecyltyrosine
    • RefChem:185429
    • 277-425-5
    • Octadecyl L-tyrosinate
    • octadecyl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate
    • octadecyl tyrosinate
    • L-Tyrosine, octadecyl ester
    • EINECS 277-425-5
    • SCHEMBL620469
    • orb1985290
    • DTXSID10994108
    • TQP1048
    • OZSVSBMHEZAZTL-SANMLTNESA-N
    • AKOS040754087
    • NS00059562
    • (S)-octadecyl 2-amino-3-(4-hydroxyphenyl)propanoate
    • 73393-27-8

  • Applications

    Stearyl tyrosine (CAS 73393-27-8) is a long-chain fatty amino acid derivative that is typically used as a surface-active intermediate and building block for surfactant systems. In cosmetics and personal care, it can function as an emulsifying agent and a conditioning-like component, aiding the dispersion of oil phases and stabilizing formulations. In coatings, inks, and plastics, it is used as a dispersant and surface modifier to improve pigment compatibility and flow, and can serve as a linker to tailor polymer–oil interfaces. It is also considered an intermediate or monomer for the synthesis of longer-chain surfactants and polymeric additives used in industrial cleaning formulations and other manufacturing processes. Its specific application depends on regional regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 27.21
    methanol 54.38
    isopropanol 19.29
    water 1.52
    ethyl acetate 86.21
    n-propanol 27.13
    acetone 115.31
    n-butanol 23.85
    acetonitrile 43.51
    DMF 136.2
    toluene 28.95
    isobutanol 22.42
    1,4-dioxane 117.9
    methyl acetate 73.47
    THF 288.91
    2-butanone 90.77
    n-pentanol 23.5
    sec-butanol 24.6
    n-hexane 3.83
    ethylene glycol 4.91
    NMP 278.09
    cyclohexane 18.03
    DMSO 338.28
    n-butyl acetate 61.11
    n-octanol 21.47
    chloroform 262.73
    n-propyl acetate 88.38
    acetic acid 102.83
    dichloromethane 300.79
    cyclohexanone 256.95
    propylene glycol 9.47
    isopropyl acetate 71.29
    DMAc 299.6
    2-ethoxyethanol 70.83
    isopentanol 25.49
    n-heptane 3.92
    ethyl formate 68.73
    1,2-dichloroethane 192.14
    n-hexanol 16.24
    2-methoxyethanol 82.8
    isobutyl acetate 50.57
    tetrachloromethane 71.67
    n-pentyl acetate 113.17
    transcutol 252.84
    n-heptanol 28.07
    ethylbenzene 20.25
    MIBK 59.77
    2-propoxyethanol 51.27
    tert-butanol 36.0
    MTBE 46.45
    2-butoxyethanol 86.99
    propionic acid 60.84
    o-xylene 29.14
    formic acid 41.67
    diethyl ether 35.52
    m-xylene 19.79
    p-xylene 31.17
    chlorobenzene 60.63
    dimethyl carbonate 52.56
    n-octane 3.19
    formamide 85.52
    cyclopentanone 263.31
    2-pentanone 77.54
    anisole 43.55
    cyclopentyl methyl ether 99.55
    gamma-butyrolactone 303.92
    1-methoxy-2-propanol 63.2
    pyridine 112.0
    3-pentanone 78.1
    furfural 208.03
    n-dodecane 1.89
    diethylene glycol 29.47
    diisopropyl ether 15.57
    tert-amyl alcohol 36.92
    acetylacetone 146.94
    n-hexadecane 2.16
    acetophenone 77.16
    methyl propionate 78.0
    isopentyl acetate 60.32
    trichloroethylene 313.91
    n-nonanol 23.12
    cyclohexanol 53.29
    benzyl alcohol 37.62
    2-ethylhexanol 17.29
    isooctanol 27.63
    dipropyl ether 31.25
    1,2-dichlorobenzene 78.4
    ethyl lactate 44.7
    propylene carbonate 166.16
    n-methylformamide 71.41
    2-pentanol 16.86
    n-pentane 2.92
    1-propoxy-2-propanol 48.45
    1-methoxy-2-propyl acetate 79.91
    2-(2-methoxypropoxy) propanol 57.68
    mesitylene 14.8
    ε-caprolactone 224.32
    p-cymene 15.32
    epichlorohydrin 263.57
    1,1,1-trichloroethane 194.56
    2-aminoethanol 16.12
    morpholine-4-carbaldehyde 182.57
    sulfolane 498.71
    2,2,4-trimethylpentane 3.9
    2-methyltetrahydrofuran 141.27
    n-hexyl acetate 86.54
    isooctane 1.77
    2-(2-butoxyethoxy)ethanol 86.12
    sec-butyl acetate 58.37
    tert-butyl acetate 93.09
    decalin 6.73
    glycerin 21.16
    diglyme 219.48
    acrylic acid 53.13
    isopropyl myristate 25.39
    n-butyric acid 107.64
    acetyl acetate 81.65
    di(2-ethylhexyl) phthalate 29.77
    ethyl propionate 73.99
    nitromethane 219.85
    1,2-diethoxyethane 88.04
    benzonitrile 48.28
    trioctyl phosphate 23.73
    1-bromopropane 62.89
    gamma-valerolactone 364.06
    n-decanol 14.8
    triethyl phosphate 45.26
    4-methyl-2-pentanol 13.99
    propionitrile 33.67
    vinylene carbonate 140.9
    1,1,2-trichlorotrifluoroethane 221.3
    DMS 69.89
    cumene 15.54
    2-octanol 22.81
    2-hexanone 70.15
    octyl acetate 36.04
    limonene 22.71
    1,2-dimethoxyethane 142.44
    ethyl orthosilicate 44.88
    tributyl phosphate 30.02
    diacetone alcohol 94.6
    N,N-dimethylaniline 34.25
    acrylonitrile 41.6
    aniline 38.82
    1,3-propanediol 29.43
    bromobenzene 62.97
    dibromomethane 161.67
    1,1,2,2-tetrachloroethane 308.67
    2-methyl-cyclohexyl acetate 58.69
    tetrabutyl urea 44.65
    diisobutyl methanol 13.64
    2-phenylethanol 31.3
    styrene 23.65
    dioctyl adipate 51.65
    dimethyl sulfate 130.56
    ethyl butyrate 67.44
    methyl lactate 49.47
    butyl lactate 84.97
    diethyl carbonate 46.59
    propanediol butyl ether 59.28
    triethyl orthoformate 59.88
    p-tert-butyltoluene 14.77
    methyl 4-tert-butylbenzoate 85.54
    morpholine 134.65
    tert-butylamine 19.67
    n-dodecanol 10.34
    dimethoxymethane 104.19
    ethylene carbonate 132.54
    cyrene 80.65
    2-ethoxyethyl acetate 147.43
    2-ethylhexyl acetate 49.72
    1,2,4-trichlorobenzene 97.33
    4-methylpyridine 85.66
    dibutyl ether 36.0
    2,6-dimethyl-4-heptanol 13.64
    DEF 111.54
    dimethyl isosorbide 131.81
    tetrachloroethylene 219.24
    eugenol 72.24
    triacetin 120.43
    span 80 54.18
    1,4-butanediol 14.9
    1,1-dichloroethane 131.07
    2-methyl-1-pentanol 25.84
    methyl formate 64.45
    2-methyl-1-butanol 26.1
    n-decane 4.09
    butyronitrile 37.22
    3,7-dimethyl-1-octanol 19.98
    1-chlorooctane 19.52
    1-chlorotetradecane 6.29
    n-nonane 3.64
    undecane 2.58
    tert-butylcyclohexane 4.78
    cyclooctane 4.5
    cyclopentanol 57.89
    tetrahydropyran 128.21
    tert-amyl methyl ether 43.32
    2,5,8-trioxanonane 115.53
    1-hexene 11.58
    2-isopropoxyethanol 52.01
    2,2,2-trifluoroethanol 76.01
    methyl butyrate 105.82

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction