Stearoyl Sarcosine

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  • Identifiers

    CAS number
    142-48-3

    Molecular formula
    C21H41NO3

    SMILES
    CCCCCCCCCCCCCCCCCC(=O)N(C)CC(=O)O

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Waxy 54.82%
    Fatty 45.58%
    Odorless 33.94%
    Oily 29.71%
    Woody 28.13%
    Savory 27.87%
    Meaty 26.3%
    Milky 25.72%
    Animal 23.79%
    Fresh 23.44%

     

    Flavor
    Bland 37.48%
    Fatty 36.09%
    Mild 35.15%
    Odorless 32.85%
    Waxy 31.14%
    Faint 28.43%
    Oily 26.8%
    Slightly waxy 23.91%
    Fat 23.53%
    Bay oil 22.58%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.7

    pKa est.
    7.24 (neutral)

    Molecular weight
    355.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    484°C

    Flash point

    • 222.58 ˚C est.

  • Synonyms

    • Stearoyl sarcosine
    • 142-48-3
    • n-stearoylsarcosine
    • Glycine, N-methyl-N-(1-oxooctadecyl)-
    • UNII-AJ0EI4K4R8
    • AJ0EI4K4R8
    • SARKOSYL S
    • Stearoyl N-methylaminoacetic acid
    • Stearoyl N-methylglycine
    • EINECS 205-539-7
    • SARCOSINE, N-STEAROYL-
    • N-OCTADECANOYL-SARCOSINE
    • DTXSID8059716
    • N-Methyl-N-(1-oxooctadecyl)glycine
    • (N-METHYL-N-OCTADECANOYLAMINO)ACETIC ACID
    • RefChem:185410
    • DTXCID4034609
    • STEAROYL SARCOSINE [INCI]
    • 205-539-7
    • n-methyl-n-stearoylglycine
    • 2-(N-Methylstearamido)acetic acid
    • 2-[methyl(octadecanoyl)amino]acetic acid
    • N-(1-Oxooctadecyl)sarcosine
    • 2-(N-methyloctadecanamido)acetic acid
    • stearoyl sarcosin
    • N-methyl-N-octadecanoylglycine
    • SCHEMBL219261
    • 2-(N-Methylstearamido)aceticacid
    • RJYOKYDKKOFLBT-UHFFFAOYSA-N
    • AS-82410
    • DB-042632
    • CS-0111609
    • NS00014119
    • D76996
    • Q27273945
    • 142-48-3

  • Applications

    Stearoyl Sarcosine, CAS 142-48-3, is used as a mild amphoteric surfactant and emulsifier in cosmetics and personal care, helping to stabilize emulsions, improve cleansing performance, and provide conditioning in products such as facial cleansers, body washes, and shampoos. It also serves as a surfactant and dispersant in household cleaning products and detergents, enhancing wetting and cleaning efficiency. In industrial manufacturing, it can function as a surfactant or processing aid in coatings, inks, and polymer formulations, aiding pigment dispersion and flow properties. It may be evaluated as a biodegradable, more environmentally friendly surfactant option for formulators seeking milder, sustainable additives. Some specialty formulations may use Stearoyl Sarcosine as an intermediate or functional additive, depending on local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 12.49
    methanol 25.4
    isopropanol 13.7
    water 0.14
    ethyl acetate 45.06
    n-propanol 17.27
    acetone 39.9
    n-butanol 17.21
    acetonitrile 18.78
    DMF 123.01
    toluene 22.04
    isobutanol 17.29
    1,4-dioxane 61.17
    methyl acetate 41.34
    THF 196.78
    2-butanone 57.52
    n-pentanol 19.72
    sec-butanol 21.52
    n-hexane 3.89
    ethylene glycol 2.48
    NMP 334.81
    cyclohexane 14.18
    DMSO 179.13
    n-butyl acetate 58.56
    n-octanol 20.45
    chloroform 185.4
    n-propyl acetate 79.02
    acetic acid 41.28
    dichloromethane 199.98
    cyclohexanone 214.57
    propylene glycol 7.11
    isopropyl acetate 50.52
    DMAc 305.92
    2-ethoxyethanol 60.85
    isopentanol 25.64
    n-heptane 2.87
    ethyl formate 34.62
    1,2-dichloroethane 130.93
    n-hexanol 14.89
    2-methoxyethanol 53.69
    isobutyl acetate 51.58
    tetrachloromethane 44.84
    n-pentyl acetate 102.86
    transcutol 264.78
    n-heptanol 20.66
    ethylbenzene 20.09
    MIBK 57.04
    2-propoxyethanol 49.74
    tert-butanol 33.95
    MTBE 44.02
    2-butoxyethanol 74.45
    propionic acid 35.95
    o-xylene 27.07
    formic acid 15.18
    diethyl ether 21.66
    m-xylene 19.78
    p-xylene 31.42
    chlorobenzene 44.26
    dimethyl carbonate 22.5
    n-octane 2.21
    formamide 32.17
    cyclopentanone 213.07
    2-pentanone 53.45
    anisole 43.18
    cyclopentyl methyl ether 82.87
    gamma-butyrolactone 205.73
    1-methoxy-2-propanol 56.13
    pyridine 83.29
    3-pentanone 51.63
    furfural 160.23
    n-dodecane 1.34
    diethylene glycol 24.08
    diisopropyl ether 13.23
    tert-amyl alcohol 42.64
    acetylacetone 84.49
    n-hexadecane 1.58
    acetophenone 76.07
    methyl propionate 45.46
    isopentyl acetate 67.75
    trichloroethylene 227.18
    n-nonanol 21.42
    cyclohexanol 46.23
    benzyl alcohol 35.51
    2-ethylhexanol 17.7
    isooctanol 23.07
    dipropyl ether 25.96
    1,2-dichlorobenzene 65.23
    ethyl lactate 40.24
    propylene carbonate 122.54
    n-methylformamide 42.68
    2-pentanol 15.14
    n-pentane 2.4
    1-propoxy-2-propanol 49.94
    1-methoxy-2-propyl acetate 71.12
    2-(2-methoxypropoxy) propanol 68.84
    mesitylene 16.57
    ε-caprolactone 192.64
    p-cymene 16.21
    epichlorohydrin 198.54
    1,1,1-trichloroethane 133.58
    2-aminoethanol 9.72
    morpholine-4-carbaldehyde 184.04
    sulfolane 422.04
    2,2,4-trimethylpentane 4.48
    2-methyltetrahydrofuran 124.81
    n-hexyl acetate 85.65
    isooctane 2.02
    2-(2-butoxyethoxy)ethanol 89.61
    sec-butyl acetate 61.29
    tert-butyl acetate 83.44
    decalin 8.34
    glycerin 16.05
    diglyme 211.89
    acrylic acid 30.07
    isopropyl myristate 25.23
    n-butyric acid 68.73
    acetyl acetate 39.21
    di(2-ethylhexyl) phthalate 30.63
    ethyl propionate 61.02
    nitromethane 88.2
    1,2-diethoxyethane 76.27
    benzonitrile 42.78
    trioctyl phosphate 20.95
    1-bromopropane 55.45
    gamma-valerolactone 297.92
    n-decanol 13.05
    triethyl phosphate 44.67
    4-methyl-2-pentanol 14.93
    propionitrile 22.77
    vinylene carbonate 93.02
    1,1,2-trichlorotrifluoroethane 168.94
    DMS 53.53
    cumene 16.98
    2-octanol 18.51
    2-hexanone 67.06
    octyl acetate 33.95
    limonene 26.22
    1,2-dimethoxyethane 139.22
    ethyl orthosilicate 43.28
    tributyl phosphate 30.38
    diacetone alcohol 98.25
    N,N-dimethylaniline 39.39
    acrylonitrile 27.26
    aniline 28.19
    1,3-propanediol 17.44
    bromobenzene 49.52
    dibromomethane 113.31
    1,1,2,2-tetrachloroethane 249.22
    2-methyl-cyclohexyl acetate 65.27
    tetrabutyl urea 49.44
    diisobutyl methanol 14.57
    2-phenylethanol 30.06
    styrene 22.14
    dioctyl adipate 54.17
    dimethyl sulfate 69.86
    ethyl butyrate 61.05
    methyl lactate 31.28
    butyl lactate 74.11
    diethyl carbonate 37.31
    propanediol butyl ether 56.77
    triethyl orthoformate 55.57
    p-tert-butyltoluene 15.32
    methyl 4-tert-butylbenzoate 85.4
    morpholine 97.05
    tert-butylamine 21.07
    n-dodecanol 8.59
    dimethoxymethane 50.67
    ethylene carbonate 81.86
    cyrene 91.45
    2-ethoxyethyl acetate 113.83
    2-ethylhexyl acetate 56.4
    1,2,4-trichlorobenzene 85.54
    4-methylpyridine 78.28
    dibutyl ether 36.72
    2,6-dimethyl-4-heptanol 14.57
    DEF 105.75
    dimethyl isosorbide 159.9
    tetrachloroethylene 159.43
    eugenol 76.27
    triacetin 108.02
    span 80 60.67
    1,4-butanediol 10.27
    1,1-dichloroethane 92.7
    2-methyl-1-pentanol 28.65
    methyl formate 29.03
    2-methyl-1-butanol 24.65
    n-decane 3.11
    butyronitrile 25.69
    3,7-dimethyl-1-octanol 21.44
    1-chlorooctane 19.46
    1-chlorotetradecane 5.35
    n-nonane 2.87
    undecane 1.9
    tert-butylcyclohexane 5.94
    cyclooctane 3.48
    cyclopentanol 49.36
    tetrahydropyran 87.08
    tert-amyl methyl ether 47.54
    2,5,8-trioxanonane 117.01
    1-hexene 12.65
    2-isopropoxyethanol 49.67
    2,2,2-trifluoroethanol 29.95
    methyl butyrate 102.3

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction