Spiroxamine

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  • Identifiers

    CAS number
    118134-30-8

    Molecular formula
    C18H35NO2

    SMILES
    CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Mint 39.22%
    Fishy 37.99%
    Cooling 37.71%
    Animal 30.07%
    Woody 27.31%
    Odorless 26.59%
    Oily 26.25%
    Grapefruit 24.03%
    Fresh 22.56%
    Ripe 21.45%

     

    Flavor
    Green 50.69%
    Earthy 29.71%
    Herbal 29.54%
    Pepper 26.04%
    Minty 25.13%
    Mild 24.11%
    Metallic 23.77%
    Spice 22.62%
    Tomato leaf 22.42%
    Tropical 22.15%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    8.32 (weak base)

    Molecular weight
    297.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    353°C

    Flash point

    • 138.64 ˚C est.

  • Synonyms

    • Spiroxamine
    • 118134-30-8
    • Impulse
    • OUT5YHB7BO
    • KWG4168
    • DTXSID1034212
    • KWG-4168
    • CHEBI:9242
    • DTXCID9014212
    • 1,4-Dioxaspiro(4.5)decane-2-methanamine, 8-(1,1-dimethylethyl)-N-ethyl-N-propyl-
    • 8-(1,1-dimethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro(4.5)decane-2-methanamine
    • N-[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]-N-ethylpropan-1-amine
    • (8-Tert-butyl-1,4-dioxa-spiro(4.5)dec-2-ylmethyl)-ethyl-propyl-amine
    • (8-tert-Butyl-1,4-dioxa-spiro[4.5]dec-2-ylmethyl)-ethyl-propyl-amine
    • 8-(1,1-dimethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro[4.5]decane-2-methanamine
    • N-((8-tert-butyl-1,4-dioxaspiro(4.5)dec-2-yl)methyl)-N-ethylpropan-1-amine
    • RefChem:184959
    • GlyTouCan:G05786IH
    • G05786IH
    • ((8-tert-butyl-1,4-dioxaspiro(4.5)decan-2-yl)methyl)(ethyl)propylamine
    • spiroxamine (ISO); 8-tert-butyl-1,4-dioxaspiro(4.5)decan-2-ylmethyl(ethyl)(propyl)amine
    • 601-505-4
    • Prosper
    • N-((8-(tert-Butyl)-1,4-dioxaspiro[4.5]decan-2-yl)methyl)-N-ethylpropan-1-amine
    • Spiroxamine [ISO]
    • C18H35NO2
    • MFCD03095708
    • N-Ethyl-N-propyl-8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-ylmethylamine
    • Spiroxamine 10 microg/mL in Acetonitrile
    • N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine
    • UNII-OUT5YHB7BO
    • piroxamine
    • Spiroxamine isomer I
    • SPIROKETALAMINE
    • Spiroxamine Isomer 1
    • Spiroxamine Isomer 2
    • Spiroxamine isomer II
    • SPIROXAMINE-1
    • SPIROXAMINE-2
    • SPIROXAMINE [MI]
    • SCHEMBL20282
    • CHEMBL445338
    • orb1303887
    • orb3025083
    • GLXC-22183
    • MSK21255
    • Tox21_301163
    • 8-tert-butyl-1,4-dioxaspiro(4.5)decan-2-ylmethyl(ethyl)(propyl)amine
    • AKOS015895921
    • N-[(8-tert-Butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]-N-ethylpropan-1-amin
    • FS27867
    • N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethyl-propan-1-amine
    • NCGC00164315-01
    • NCGC00164315-02
    • NCGC00164315-03
    • NCGC00255061-01
    • DB-061262
    • HY-121884
    • CAS-118134-30-8
    • NS00009694
    • F87643
    • Spiroxamine, PESTANAL(R), analytical standard
    • 134S308
    • Q1850388
    • N-[(8-tert-Butyl-1,4-dioxaspiro[4.5]decan-2-yl)methyl]-N-ethylpropan-1-amine
    • 118134-30-8

  • Applications

    Spiroxamine (CAS 118134-30-8) is an agricultural fungicide active ingredient used in crop protection products to control fungal diseases on crops. It is formulated in product types such as emulsifiable concentrates (EC), suspension concentrates (SC), and water-dispersible granules (WG) for use on crops in field and greenhouse settings. It is commonly integrated into pest management programs and rotated with other fungicides to mitigate resistance development. Use is subject to local regulations and label directions, including application timing, rates, and crop-specific restrictions.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1204.18
    methanol 1060.7
    isopropanol 851.43
    water 18.81
    ethyl acetate 3355.75
    n-propanol 1131.94
    acetone 1832.71
    n-butanol 1168.16
    acetonitrile 1168.8
    DMF 1881.42
    toluene 1391.16
    isobutanol 1047.76
    1,4-dioxane 2197.44
    methyl acetate 2144.7
    THF 2827.05
    2-butanone 1693.81
    n-pentanol 684.03
    sec-butanol 928.35
    n-hexane 166.46
    ethylene glycol 265.02
    NMP 2940.84
    cyclohexane 505.11
    DMSO 1401.34
    n-butyl acetate 2047.1
    n-octanol 519.03
    chloroform 7531.01
    n-propyl acetate 1596.77
    acetic acid 3339.9
    dichloromethane 6422.3
    cyclohexanone 2974.67
    propylene glycol 351.69
    isopropyl acetate 2569.94
    DMAc 2636.66
    2-ethoxyethanol 1121.93
    isopentanol 1156.17
    n-heptane 131.29
    ethyl formate 1539.63
    1,2-dichloroethane 3353.91
    n-hexanol 920.92
    2-methoxyethanol 1703.89
    isobutyl acetate 1346.43
    tetrachloromethane 1568.03
    n-pentyl acetate 1338.46
    transcutol 4461.32
    n-heptanol 530.27
    ethylbenzene 582.02
    MIBK 1310.1
    2-propoxyethanol 1665.35
    tert-butanol 942.99
    MTBE 1639.54
    2-butoxyethanol 1132.84
    propionic acid 1802.11
    o-xylene 944.42
    formic acid 1235.13
    diethyl ether 1652.39
    m-xylene 1082.34
    p-xylene 859.33
    chlorobenzene 2100.53
    dimethyl carbonate 1045.77
    n-octane 59.12
    formamide 1262.73
    cyclopentanone 2543.12
    2-pentanone 1648.03
    anisole 958.27
    cyclopentyl methyl ether 2148.28
    gamma-butyrolactone 3590.22
    1-methoxy-2-propanol 1294.35
    pyridine 2037.39
    3-pentanone 1624.55
    furfural 2898.08
    n-dodecane 52.49
    diethylene glycol 988.26
    diisopropyl ether 847.83
    tert-amyl alcohol 1058.89
    acetylacetone 2390.13
    n-hexadecane 62.43
    acetophenone 1118.55
    methyl propionate 2157.67
    isopentyl acetate 2041.12
    trichloroethylene 6773.8
    n-nonanol 493.97
    cyclohexanol 1591.71
    benzyl alcohol 789.62
    2-ethylhexanol 716.84
    isooctanol 499.75
    dipropyl ether 908.79
    1,2-dichlorobenzene 1933.78
    ethyl lactate 687.0
    propylene carbonate 2609.27
    n-methylformamide 1263.28
    2-pentanol 910.82
    n-pentane 203.61
    1-propoxy-2-propanol 1227.91
    1-methoxy-2-propyl acetate 2293.53
    2-(2-methoxypropoxy) propanol 1024.42
    mesitylene 695.16
    ε-caprolactone 3568.53
    p-cymene 464.51
    epichlorohydrin 3610.58
    1,1,1-trichloroethane 4305.08
    2-aminoethanol 580.26
    morpholine-4-carbaldehyde 2803.71
    sulfolane 2899.19
    2,2,4-trimethylpentane 209.21
    2-methyltetrahydrofuran 2884.42
    n-hexyl acetate 1821.91
    isooctane 120.44
    2-(2-butoxyethoxy)ethanol 1401.3
    sec-butyl acetate 1463.23
    tert-butyl acetate 2162.13
    decalin 254.03
    glycerin 556.05
    diglyme 2619.79
    acrylic acid 1412.75
    isopropyl myristate 626.2
    n-butyric acid 3067.43
    acetyl acetate 3109.73
    di(2-ethylhexyl) phthalate 555.66
    ethyl propionate 1476.36
    nitromethane 3936.78
    1,2-diethoxyethane 1651.92
    benzonitrile 1115.14
    trioctyl phosphate 409.08
    1-bromopropane 1885.7
    gamma-valerolactone 4057.8
    n-decanol 343.9
    triethyl phosphate 744.67
    4-methyl-2-pentanol 666.45
    propionitrile 992.13
    vinylene carbonate 2388.22
    1,1,2-trichlorotrifluoroethane 3093.69
    DMS 1481.25
    cumene 456.27
    2-octanol 372.27
    2-hexanone 1007.52
    octyl acetate 772.57
    limonene 760.41
    1,2-dimethoxyethane 1438.57
    ethyl orthosilicate 773.27
    tributyl phosphate 618.14
    diacetone alcohol 1309.05
    N,N-dimethylaniline 624.65
    acrylonitrile 1043.99
    aniline 1403.87
    1,3-propanediol 967.71
    bromobenzene 2347.25
    dibromomethane 3977.51
    1,1,2,2-tetrachloroethane 5370.11
    2-methyl-cyclohexyl acetate 1114.69
    tetrabutyl urea 608.66
    diisobutyl methanol 406.76
    2-phenylethanol 912.96
    styrene 709.6
    dioctyl adipate 870.45
    dimethyl sulfate 1590.0
    ethyl butyrate 1462.02
    methyl lactate 838.65
    butyl lactate 974.41
    diethyl carbonate 1023.44
    propanediol butyl ether 811.05
    triethyl orthoformate 1120.78
    p-tert-butyltoluene 448.94
    methyl 4-tert-butylbenzoate 1103.65
    morpholine 2484.82
    tert-butylamine 670.87
    n-dodecanol 260.59
    dimethoxymethane 1567.56
    ethylene carbonate 2315.76
    cyrene 811.33
    2-ethoxyethyl acetate 1906.78
    2-ethylhexyl acetate 1697.6
    1,2,4-trichlorobenzene 2319.98
    4-methylpyridine 2404.16
    dibutyl ether 784.17
    2,6-dimethyl-4-heptanol 406.76
    DEF 2117.98
    dimethyl isosorbide 1707.79
    tetrachloroethylene 3735.04
    eugenol 779.69
    triacetin 1724.12
    span 80 855.16
    1,4-butanediol 398.27
    1,1-dichloroethane 3580.2
    2-methyl-1-pentanol 765.4
    methyl formate 1125.35
    2-methyl-1-butanol 1190.4
    n-decane 98.7
    butyronitrile 1103.36
    3,7-dimethyl-1-octanol 606.78
    1-chlorooctane 516.07
    1-chlorotetradecane 191.66
    n-nonane 90.44
    undecane 68.34
    tert-butylcyclohexane 210.89
    cyclooctane 186.98
    cyclopentanol 1343.76
    tetrahydropyran 2531.3
    tert-amyl methyl ether 1412.53
    2,5,8-trioxanonane 1552.01
    1-hexene 467.81
    2-isopropoxyethanol 885.18
    2,2,2-trifluoroethanol 1764.14
    methyl butyrate 1726.3

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction