Spiro(2,4-dithia-1-methyl-8-oxabicyclo(3.3.0)octane-3,3'-(1'-oxa-2'-methyl)cyclopentane)

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  • Identifiers

    CAS number
    38325-25-6

    Molecular formula
    C10H16O2S2

    SMILES
    CC1C2(CCO1)SC3CCOC3(S2)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Meaty 69.43%
    Sulfurous 47.2%
    Roasted 46.6%
    Onion 37.07%
    Savory 33.44%
    Cooked 33.33%
    Nutty 29.79%
    Beefy 26.65%
    Alliaceous 25.67%
    Sweet 22.41%

     

    Flavor
    Sulfurous 40.5%
    Roasted 39.15%
    Vegetable 30.6%
    Savory 26.89%
    Meaty 26.8%
    Chicken 26.63%
    Onion 25.41%
    Bouillon 25.29%
    Alliaceous 25.2%
    Green 25.1%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.1

    pKa est.
    4.45 (weak acid)

    Molecular weight
    232.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point

    • 135.00 to 140.00 °C. @ 3.00 mm Hg

    Flash point

    • 141.87 ˚C est.

  • Synonyms

    • 38325-25-6
    • FEMA No. 3270
    • Hexahydro-2'3a-dimethylspiro[1,3-dithiolo[4,5-b]furan-2,3'(2'H)-furan]
    • Spiro(1,3-dithiolo(4,5-b)furan-2,3'(2'H)-furan), hexahydro-2',3a-dimethyl-
    • TER5ZXE00D
    • EINECS 253-884-7
    • 2',3a-dimethylspiro[6,6a-dihydro-5H-[1,3]dithiolo[4,5-b]furan-2,3'-oxolane]
    • Spiro(2,4-dithia-1-methyl-8-oxabicyclo(3.3.0)octane-3,3'-(1'-oxa-2'-methyl)cyclopentane)
    • DTXSID70865906
    • 2',3a-Dimethylhexahydro-2'H-spiro[[1,3]dithiolo[4,5-b]furan-2,3'-furan]
    • Hexahydro-2',3a-dimethylspiro(1,3-dithiolo(4,5-b)furan-2,3'(2'H)-furan)
    • Spiro[1,3-dithiolo[4,5-b]furan-2,3'(2'H)-furan], hexahydro-2',3a-dimethyl-
    • Spiro(2,4-dithia-1-methyl-8-oxabicyclo(3.3.0)octane-3,3'- (1'-oxa-2'-methyl)cyclopentane)
    • Spiro(2,4-dithia-1-methyl-8-oxabicyclo(3.3.0)octane-3,3'-(1'-oxa-2-methyl)cyclopentane)
    • Spiro(2,4-dithia-1-methyl-8-oxabicyclo(3.3.0)octane-3,3'-l(1'-oxa-2'-methyl)-cyclopentane
    • Hexahydro-2'3a-dimethylspiro(1,3-dithiolo(4,5-b)furan-2,3'(2'H)-furan)
    • 2',3-DIMETHYL-3',4-DIOXA-2,8-DITHIABICYCLO(3.3.0)OCTANESPIROCYCLOPENTANE
    • 2',3a-dimethylspiro[6,6a-dihydro-5H-[1,3]dithiolo[4,5-b]furan-2,3'-tetrahydrofuran]
    • Hexahydro-2',3alpha-dimethylspiro[1,3-dithiolo[4,5-b]furan-2,3'(2'H)-furan]
    • UNII-TER5ZXE00D
    • Hexahydro-2',3a-dimethylspiro[1,3-dithiolo[4,5-b]furan-2,3'(2'H)-furan]
    • 2',3-DIMETHYL-3',4-DIOXA-2,8-DITHIABICYCLO[3.3.0]OCTANESPIROCYCLOPENTANE
    • SCHEMBL3504545
    • DTXCID20814262
    • LGPJANFPSFABDB-UHFFFAOYSA-N
    • 2',3-dimethyl-3',4-dioxa-2,8-dithiabicyclo(3.3.0)octane spirocyclopentane
    • AKOS015950886
    • FH152469
    • NS00056523
    • Q27289930
    • 2',3a-dimethyl-tetrahydrospiro[[1,3]dithiolo[4,5-b]furan-2,3'-oxolane]
    • SPIRO(2,4-DITHIA-1-METHYL-8-OXABICYCLO(3.3.0)OCTANE-3,3'- (1'-OXA-2'-METHYL)CYCLOPENTANE) PLUS SPIRO(DITHIA-6-METHYL-7-OXABICYCLO(3.3.0)OCTANE-3,3'- (1'-OXA-2-METHYL)CYCLOPENTANE) [FHFI]
    • SPIRO(2,4-DITHIA-1-METHYL-8-OXABICYCLO(3.3.0)OCTANE-3,3'-(1'-OXA-2'-METHYL)CYCLOPENTANE) PLUS SPIRO(DITHIA-6-METHYL-7-OXABICYCLO(3.3.0)OCTANE-3,3'-(1'-OXA-2-METHYL)CYCLOPENTANE)
    • SPIRO(2,4-DITHIA-1-METHYL-8-OXABICYCLO(3.3.0)OCTANE-3,3'-(1'-OXA-2'-METHYL)CYCLOPENTANE) PLUS SPIRO(DITHIA-6-METHYL-7-OXABICYCLO(3.3.0)OCTANE-3,3'-(1'-OXA-2-METHYL)CYCLOPENTANE) [FHFI]

  • Applications

    Chemical name: Spiro(2,4-dithia-1-methyl-8-oxabicyclo(3.3.0)octane-3,3'-(1'-oxa-2'-methyl)cyclopentane); CAS number: 38325-25-6 can serve as an intermediate and specialty formulation additive across multiple industries, with typical applications including polymers/plastics as a processing aid or stabilizer, coatings and inks as a compatibility modifier or crosslinking helper, adhesives as a performance-enhancing additive, cosmetics/personal care as a fragrance fixative or odor carrier, and household products as a solvent or coupling agent. It may also be evaluated for other roles in industrial manufacturing or as a basis for further synthesis, subject to formulation limits and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 94.36
    methanol 184.43
    isopropanol 90.68
    water 21.0
    ethyl acetate 232.02
    n-propanol 89.71
    acetone 412.43
    n-butanol 78.8
    acetonitrile 297.75
    DMF 1129.17
    toluene 156.78
    isobutanol 73.95
    1,4-dioxane 523.41
    methyl acetate 293.51
    THF 507.51
    2-butanone 250.79
    n-pentanol 54.78
    sec-butanol 59.69
    n-hexane 1.12
    ethylene glycol 128.76
    NMP 565.08
    cyclohexane 11.67
    DMSO 730.54
    n-butyl acetate 155.15
    n-octanol 77.7
    chloroform 896.21
    n-propyl acetate 148.74
    acetic acid 176.16
    dichloromethane 769.35
    cyclohexanone 479.18
    propylene glycol 89.28
    isopropyl acetate 169.49
    DMAc 649.16
    2-ethoxyethanol 222.01
    isopentanol 72.88
    n-heptane 4.63
    ethyl formate 271.25
    1,2-dichloroethane 372.05
    n-hexanol 78.95
    2-methoxyethanol 447.59
    isobutyl acetate 121.5
    tetrachloromethane 133.35
    n-pentyl acetate 140.78
    transcutol 399.71
    n-heptanol 65.36
    ethylbenzene 61.25
    MIBK 159.67
    2-propoxyethanol 294.63
    tert-butanol 105.83
    MTBE 73.27
    2-butoxyethanol 175.88
    propionic acid 145.49
    o-xylene 117.45
    formic acid 152.85
    diethyl ether 72.02
    m-xylene 119.22
    p-xylene 103.74
    chlorobenzene 326.26
    dimethyl carbonate 251.39
    n-octane 3.62
    formamide 317.02
    cyclopentanone 605.95
    2-pentanone 203.92
    anisole 248.21
    cyclopentyl methyl ether 194.3
    gamma-butyrolactone 700.21
    1-methoxy-2-propanol 331.2
    pyridine 446.58
    3-pentanone 165.83
    furfural 912.21
    n-dodecane 6.87
    diethylene glycol 355.25
    diisopropyl ether 32.78
    tert-amyl alcohol 68.85
    acetylacetone 496.32
    n-hexadecane 8.44
    acetophenone 294.7
    methyl propionate 234.43
    isopentyl acetate 149.99
    trichloroethylene 850.93
    n-nonanol 74.69
    cyclohexanol 121.65
    benzyl alcohol 215.5
    2-ethylhexanol 59.23
    isooctanol 57.29
    dipropyl ether 60.56
    1,2-dichlorobenzene 351.23
    ethyl lactate 141.14
    propylene carbonate 392.73
    n-methylformamide 518.59
    2-pentanol 49.18
    n-pentane 2.61
    1-propoxy-2-propanol 192.46
    1-methoxy-2-propyl acetate 260.67
    2-(2-methoxypropoxy) propanol 187.97
    mesitylene 78.44
    ε-caprolactone 351.69
    p-cymene 68.68
    epichlorohydrin 641.8
    1,1,1-trichloroethane 404.59
    2-aminoethanol 126.65
    morpholine-4-carbaldehyde 856.53
    sulfolane 752.57
    2,2,4-trimethylpentane 3.42
    2-methyltetrahydrofuran 231.41
    n-hexyl acetate 171.68
    isooctane 3.67
    2-(2-butoxyethoxy)ethanol 210.62
    sec-butyl acetate 103.33
    tert-butyl acetate 173.75
    decalin 8.5
    glycerin 230.82
    diglyme 484.53
    acrylic acid 180.04
    isopropyl myristate 88.47
    n-butyric acid 184.65
    acetyl acetate 290.17
    di(2-ethylhexyl) phthalate 97.36
    ethyl propionate 149.66
    nitromethane 792.24
    1,2-diethoxyethane 161.17
    benzonitrile 402.1
    trioctyl phosphate 74.04
    1-bromopropane 103.14
    gamma-valerolactone 962.42
    n-decanol 57.81
    triethyl phosphate 98.58
    4-methyl-2-pentanol 47.65
    propionitrile 216.09
    vinylene carbonate 523.52
    1,1,2-trichlorotrifluoroethane 538.85
    DMS 229.87
    cumene 49.83
    2-octanol 51.33
    2-hexanone 128.99
    octyl acetate 108.68
    limonene 78.58
    1,2-dimethoxyethane 419.46
    ethyl orthosilicate 82.09
    tributyl phosphate 84.63
    diacetone alcohol 208.94
    N,N-dimethylaniline 154.99
    acrylonitrile 380.72
    aniline 212.84
    1,3-propanediol 181.91
    bromobenzene 348.32
    dibromomethane 342.8
    1,1,2,2-tetrachloroethane 617.81
    2-methyl-cyclohexyl acetate 144.17
    tetrabutyl urea 123.98
    diisobutyl methanol 48.61
    2-phenylethanol 205.61
    styrene 86.81
    dioctyl adipate 129.55
    dimethyl sulfate 457.18
    ethyl butyrate 138.97
    methyl lactate 228.89
    butyl lactate 134.73
    diethyl carbonate 123.01
    propanediol butyl ether 163.51
    triethyl orthoformate 110.44
    p-tert-butyltoluene 67.02
    methyl 4-tert-butylbenzoate 217.12
    morpholine 419.78
    tert-butylamine 50.61
    n-dodecanol 46.21
    dimethoxymethane 567.75
    ethylene carbonate 407.45
    cyrene 287.37
    2-ethoxyethyl acetate 230.34
    2-ethylhexyl acetate 120.69
    1,2,4-trichlorobenzene 410.26
    4-methylpyridine 430.94
    dibutyl ether 64.85
    2,6-dimethyl-4-heptanol 48.61
    DEF 268.93
    dimethyl isosorbide 363.85
    tetrachloroethylene 366.74
    eugenol 244.63
    triacetin 245.53
    span 80 153.43
    1,4-butanediol 90.83
    1,1-dichloroethane 328.38
    2-methyl-1-pentanol 49.38
    methyl formate 557.21
    2-methyl-1-butanol 60.29
    n-decane 9.45
    butyronitrile 191.57
    3,7-dimethyl-1-octanol 74.95
    1-chlorooctane 54.05
    1-chlorotetradecane 28.05
    n-nonane 7.01
    undecane 7.95
    tert-butylcyclohexane 6.91
    cyclooctane 5.13
    cyclopentanol 150.2
    tetrahydropyran 222.24
    tert-amyl methyl ether 59.97
    2,5,8-trioxanonane 353.4
    1-hexene 8.26
    2-isopropoxyethanol 152.01
    2,2,2-trifluoroethanol 213.1
    methyl butyrate 188.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction