Sodium Succinate Hexahydrate

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  • Identifiers

    CAS number
    6106-21-4

    Molecular formula
    C4H16Na2O10

    SMILES
    C(CC(=O)[O-])C(=O)[O-].O.O.O.O.O.O.[Na+].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 66.03%
    Sweet 33.69%
    Sour 31.24%
    Caramellic 25.14%
    Buttery 22.93%
    Fatty 20.08%
    Creamy 19.86%
    Winey 19.31%
    Clean 18.26%
    Burnt 18.09%

     

    Flavor
    Odorless 57.54%
    Sour 32.16%
    Very mild 28.62%
    Nutty 25.14%
    Mild 24.42%
    Musty 22.67%
    Sweet 22.52%
    Caramellic 22.42%
    Acidic 21.41%
    Yeast 21.22%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    0.49 (strong acid)

    Molecular weight
    270.14 g/mol

    Flash point

    • 124.61 ˚C est.

  • Synonyms

    • 6106-21-4
    • Sodium succinate hexahydrate
    • disodium succinate hexahydrate
    • disodium butanedioate hexahydrate
    • Butanedioic acid, disodium salt, hexahydrate
    • Sodium succinate dibasic hexahydrate
    • U16QOD6C4E
    • Succinic acid disodium salt hexahydrate
    • sodium succinate.6H2O
    • disodium succinate.6H2O
    • disodium butanedioate.6H2O
    • CHEBI:63686
    • DTXSID70209942
    • disodium butanedioate--water(1/6)
    • SODIUM SUCCINATE HEXAHYDRATE [II]
    • SODIUM SUCCINATE HEXAHYDRATE [MI]
    • BUTANEDIOIC ACID DISODIUM SALT HEXAHYDRATE
    • SODIUM SUCCINATE HEXAHYDRATE (II)
    • RefChem:887892
    • DTXCID20132433
    • 612-073-1
    • disodium;butanedioate;hexahydrate
    • C4H16Na2O10
    • MFCD00149117
    • UNII-U16QOD6C4E
    • SCHEMBL351829
    • orb2939183
    • SODIUM SUCCINATE [VANDF]
    • Sodium Succinate Hexahydrate [NF]
    • AKOS015892836
    • Sodium butanedioate--water (2/1/6)
    • SODIUM SUCCINATE [ORANGE BOOK]
    • Succinic acid,disodium salt hexahydrate
    • A833027
    • F510240
    • Q27132724
    • 6106-21-4

  • Applications

    Sodium succinate hexahydrate (CAS 6106-21-4) is used across several industrial and formulation contexts as a buffering and stabilizing agent: it helps maintain pH in pharmaceutical and cosmetic products and can act as a mild stabilizer for sensitive ingredients. In cleaning and household formulations it can function as a chelating/sequestering agent to bind metal ions and improve the performance of surfactants. It is also encountered as an intermediate in organic synthesis and chemical manufacturing, and may be used as a nutrient source or additive in fermentation-based processes. Depending on the formulation, its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 133.39
    methanol 267.3
    isopropanol 85.0
    water 40.18
    ethyl acetate 94.55
    n-propanol 68.55
    acetone 273.27
    n-butanol 47.8
    acetonitrile 294.12
    DMF 708.21
    toluene 33.54
    isobutanol 47.09
    1,4-dioxane 253.39
    methyl acetate 251.22
    THF 177.42
    2-butanone 177.37
    n-pentanol 45.64
    sec-butanol 68.28
    n-hexane 9.07
    ethylene glycol 59.73
    NMP 634.03
    cyclohexane 6.2
    DMSO 1029.86
    n-butyl acetate 43.64
    n-octanol 27.85
    chloroform 98.84
    n-propyl acetate 66.64
    acetic acid 177.84
    dichloromethane 215.07
    cyclohexanone 115.1
    propylene glycol 36.16
    isopropyl acetate 49.38
    DMAc 903.84
    2-ethoxyethanol 194.67
    isopentanol 45.53
    n-heptane 4.27
    ethyl formate 155.13
    1,2-dichloroethane 160.56
    n-hexanol 22.16
    2-methoxyethanol 269.87
    isobutyl acetate 25.54
    tetrachloromethane 17.41
    n-pentyl acetate 35.33
    transcutol 290.68
    n-heptanol 16.77
    ethylbenzene 33.67
    MIBK 44.35
    2-propoxyethanol 81.26
    tert-butanol 116.16
    MTBE 110.66
    2-butoxyethanol 56.86
    propionic acid 103.39
    o-xylene 42.37
    formic acid 239.98
    diethyl ether 81.93
    m-xylene 21.93
    p-xylene 50.06
    chlorobenzene 49.14
    dimethyl carbonate 105.04
    n-octane 3.28
    formamide 603.66
    cyclopentanone 171.7
    2-pentanone 77.67
    anisole 129.45
    cyclopentyl methyl ether 60.86
    gamma-butyrolactone 316.69
    1-methoxy-2-propanol 124.06
    pyridine 174.92
    3-pentanone 78.5
    furfural 430.43
    n-dodecane 3.45
    diethylene glycol 95.88
    diisopropyl ether 20.77
    tert-amyl alcohol 103.76
    acetylacetone 136.4
    n-hexadecane 3.76
    acetophenone 136.76
    methyl propionate 104.57
    isopentyl acetate 37.11
    trichloroethylene 207.36
    n-nonanol 26.5
    cyclohexanol 32.56
    benzyl alcohol 79.46
    2-ethylhexanol 15.46
    isooctanol 14.46
    dipropyl ether 27.79
    1,2-dichlorobenzene 64.69
    ethyl lactate 43.24
    propylene carbonate 138.4
    n-methylformamide 379.99
    2-pentanol 31.74
    n-pentane 6.88
    1-propoxy-2-propanol 45.09
    1-methoxy-2-propyl acetate 55.4
    2-(2-methoxypropoxy) propanol 102.32
    mesitylene 15.4
    ε-caprolactone 125.48
    p-cymene 15.42
    epichlorohydrin 313.0
    1,1,1-trichloroethane 74.01
    2-aminoethanol 79.42
    morpholine-4-carbaldehyde 562.21
    sulfolane 411.42
    2,2,4-trimethylpentane 5.53
    2-methyltetrahydrofuran 126.39
    n-hexyl acetate 52.11
    isooctane 2.35
    2-(2-butoxyethoxy)ethanol 110.99
    sec-butyl acetate 35.49
    tert-butyl acetate 58.19
    decalin 7.02
    glycerin 66.92
    diglyme 281.28
    acrylic acid 124.88
    isopropyl myristate 24.49
    n-butyric acid 62.14
    acetyl acetate 80.28
    di(2-ethylhexyl) phthalate 32.05
    ethyl propionate 64.27
    nitromethane 729.94
    1,2-diethoxyethane 99.71
    benzonitrile 101.13
    trioctyl phosphate 18.72
    1-bromopropane 60.6
    gamma-valerolactone 338.32
    n-decanol 20.4
    triethyl phosphate 38.0
    4-methyl-2-pentanol 19.06
    propionitrile 108.81
    vinylene carbonate 160.11
    1,1,2-trichlorotrifluoroethane 185.39
    DMS 86.92
    cumene 24.43
    2-octanol 15.28
    2-hexanone 69.53
    octyl acetate 32.14
    limonene 18.21
    1,2-dimethoxyethane 415.19
    ethyl orthosilicate 33.13
    tributyl phosphate 26.96
    diacetone alcohol 76.23
    N,N-dimethylaniline 110.67
    acrylonitrile 197.84
    aniline 59.79
    1,3-propanediol 89.56
    bromobenzene 44.23
    dibromomethane 107.79
    1,1,2,2-tetrachloroethane 144.46
    2-methyl-cyclohexyl acetate 36.93
    tetrabutyl urea 49.33
    diisobutyl methanol 13.38
    2-phenylethanol 41.19
    styrene 44.99
    dioctyl adipate 45.8
    dimethyl sulfate 264.04
    ethyl butyrate 40.19
    methyl lactate 73.39
    butyl lactate 32.26
    diethyl carbonate 41.93
    propanediol butyl ether 55.67
    triethyl orthoformate 34.12
    p-tert-butyltoluene 15.01
    methyl 4-tert-butylbenzoate 82.09
    morpholine 225.77
    tert-butylamine 61.99
    n-dodecanol 16.38
    dimethoxymethane 226.3
    ethylene carbonate 112.07
    cyrene 111.22
    2-ethoxyethyl acetate 73.88
    2-ethylhexyl acetate 29.25
    1,2,4-trichlorobenzene 82.92
    4-methylpyridine 183.98
    dibutyl ether 37.0
    2,6-dimethyl-4-heptanol 13.38
    DEF 184.9
    dimethyl isosorbide 152.38
    tetrachloroethylene 103.85
    eugenol 79.07
    triacetin 97.31
    span 80 51.2
    1,4-butanediol 49.91
    1,1-dichloroethane 92.48
    2-methyl-1-pentanol 45.19
    methyl formate 331.78
    2-methyl-1-butanol 46.31
    n-decane 5.33
    butyronitrile 73.36
    3,7-dimethyl-1-octanol 26.53
    1-chlorooctane 17.3
    1-chlorotetradecane 9.0
    n-nonane 5.03
    undecane 4.16
    tert-butylcyclohexane 6.31
    cyclooctane 3.07
    cyclopentanol 45.04
    tetrahydropyran 79.61
    tert-amyl methyl ether 88.75
    2,5,8-trioxanonane 218.95
    1-hexene 24.79
    2-isopropoxyethanol 100.17
    2,2,2-trifluoroethanol 132.32
    methyl butyrate 94.17

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction