Sodium Pyrrolidone Carboxylate

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  • Identifiers

    CAS number
    54571-67-4

    Molecular formula
    C5H6NNaO3

    SMILES
    C1CC(=O)NC1C(=O)[O-].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 58.13%
    Sweet 56.52%
    Caramellic 31.8%
    Nutty 27.61%
    Burnt 26.08%
    Ethereal 23.1%
    Buttery 19.44%
    Popcorn 19.1%
    Savory 16.74%
    Bitter 16.6%

     

    Flavor
    Bitter 47.2%
    Odorless 43.66%
    Very mild 25.92%
    Yeast 20.14%
    Sweet-like 19.91%
    Taco 19.81%
    Nitrile 19.73%
    Bread crust 19.7%
    Urine 19.39%
    Fenugreek 19.22%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    4.19 (weak acid)

    Molecular weight
    151.1 g/mol

    Flash point

    • 169.55 ˚C est.

  • Synonyms

    • Sodium PCA
    • Sodium pyrrolidone carboxylate
    • PCA Soda
    • Nalidone
    • Sodium 5-oxo-DL-prolinate
    • Ajidew N-50
    • DL-Sodium pyroglutamate
    • Sodium DL-pyroglutamate
    • Monosodium 5-oxoproline
    • sodium dl-pyrrolidonecarboxylate
    • 5-Oxo-DL-proline, monosodium salt
    • DL-Proline, 5-oxo-, monosodium salt
    • 469OTG57A2
    • DL-SODIUM PIDOLATE
    • EINECS 259-234-9
    • Proline, 5-oxo-, sodium salt (1:1)
    • PIDOLATE SODIUM, DL-
    • DTXSID20885432
    • SODIUM DL-PYROGLUTAMATE [WHO-DD]
    • SODIUM PYRROLIDONE CARBOXYLATE [II]
    • SODIUM PYRROLIDONE CARBOXYLATE [VANDF]
    • PYRROLIDONE CARBOXYLIC ACID, SODIUM SALT
    • SODIUM PYRROLIDONE CARBOXYLATE (II)
    • Na PCA
    • RefChem:887847
    • SODIUM PCA [INCI]
    • DTXCID301024812
    • 54571-67-4
    • sodium 5-oxopyrrolidine-2-carboxylate
    • sodium;5-oxopyrrolidine-2-carboxylate
    • sodium 2-pyrrolidone-5-carboxylate
    • C5H6NNaO3
    • MFCD00066984
    • Sodium 5-oxo-L-prolinate
    • Proline, 5-oxo-, monosodium salt
    • UNII-469OTG57A2
    • 2-Pyrrolidone-5-carboxylic acid, sodium salt
    • SCHEMBL66285
    • sodium5-oxopyrrolidine-2-carboxylate
    • AKOS016010363
    • s10166
    • AS-65747
    • DB-052609
    • CS-0112985
    • NS00078265
    • Q27258924
    • 54571-67-4

  • Applications

    Sodium Pyrrolidone Carboxylate (CAS 54571-67-4) is a water-soluble salt commonly used as a humectant and skin-conditioning agent in cosmetics and personal care products, helping to retain moisture and improve texture, while also serving as a buffering agent and stabilizer in aqueous formulations such as cleansers and shampoos. In household cleaning products it functions as a humectant and as a sequestering/chelating agent for metal ions, contributing to formulation stability and cleaning performance. In industrial manufacturing, it is used as a chelating/sequestering agent to bind trace metals and as a processing aid in water-based polymer, coating, and adhesive formulations. In coatings, inks and adhesives, it can act as a processing aid and moisture-retention additive to improve compatibility with water-based systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 232.02
    methanol 641.99
    isopropanol 110.03
    water 439.48
    ethyl acetate 17.34
    n-propanol 107.69
    acetone 90.83
    n-butanol 84.65
    acetonitrile 62.95
    DMF 551.71
    toluene 5.63
    isobutanol 71.15
    1,4-dioxane 81.0
    methyl acetate 39.25
    THF 62.7
    2-butanone 43.15
    n-pentanol 71.41
    sec-butanol 76.22
    n-hexane 1.46
    ethylene glycol 196.16
    NMP 268.06
    cyclohexane 1.14
    DMSO 609.03
    n-butyl acetate 18.41
    n-octanol 30.2
    chloroform 21.88
    n-propyl acetate 20.82
    acetic acid 276.34
    dichloromethane 50.34
    cyclohexanone 49.92
    propylene glycol 107.62
    isopropyl acetate 12.8
    DMAc 347.33
    2-ethoxyethanol 234.3
    isopentanol 75.41
    n-heptane 1.23
    ethyl formate 63.64
    1,2-dichloroethane 37.94
    n-hexanol 31.44
    2-methoxyethanol 356.36
    isobutyl acetate 9.39
    tetrachloromethane 2.87
    n-pentyl acetate 20.77
    transcutol 378.74
    n-heptanol 24.55
    ethylbenzene 7.22
    MIBK 23.2
    2-propoxyethanol 99.11
    tert-butanol 102.18
    MTBE 27.28
    2-butoxyethanol 75.29
    propionic acid 76.13
    o-xylene 8.66
    formic acid 640.28
    diethyl ether 21.32
    m-xylene 6.8
    p-xylene 9.7
    chlorobenzene 10.62
    dimethyl carbonate 26.33
    n-octane 1.12
    formamide 683.4
    cyclopentanone 58.49
    2-pentanone 29.95
    anisole 32.81
    cyclopentyl methyl ether 18.63
    gamma-butyrolactone 97.65
    1-methoxy-2-propanol 155.78
    pyridine 53.67
    3-pentanone 16.83
    furfural 165.35
    n-dodecane 1.21
    diethylene glycol 166.92
    diisopropyl ether 4.95
    tert-amyl alcohol 85.4
    acetylacetone 42.47
    n-hexadecane 1.26
    acetophenone 44.2
    methyl propionate 23.89
    isopentyl acetate 18.77
    trichloroethylene 49.39
    n-nonanol 26.31
    cyclohexanol 30.6
    benzyl alcohol 58.57
    2-ethylhexanol 15.38
    isooctanol 19.6
    dipropyl ether 8.96
    1,2-dichlorobenzene 15.06
    ethyl lactate 31.18
    propylene carbonate 49.47
    n-methylformamide 300.63
    2-pentanol 39.48
    n-pentane 1.59
    1-propoxy-2-propanol 49.11
    1-methoxy-2-propyl acetate 26.47
    2-(2-methoxypropoxy) propanol 79.74
    mesitylene 4.93
    ε-caprolactone 57.4
    p-cymene 5.59
    epichlorohydrin 104.24
    1,1,1-trichloroethane 8.78
    2-aminoethanol 227.05
    morpholine-4-carbaldehyde 281.9
    sulfolane 165.19
    2,2,4-trimethylpentane 1.2
    2-methyltetrahydrofuran 37.35
    n-hexyl acetate 31.49
    isooctane 0.81
    2-(2-butoxyethoxy)ethanol 126.78
    sec-butyl acetate 11.11
    tert-butyl acetate 18.28
    decalin 1.23
    glycerin 188.02
    diglyme 197.34
    acrylic acid 108.42
    isopropyl myristate 11.5
    n-butyric acid 60.72
    acetyl acetate 16.44
    di(2-ethylhexyl) phthalate 22.64
    ethyl propionate 15.84
    nitromethane 313.46
    1,2-diethoxyethane 46.0
    benzonitrile 39.79
    trioctyl phosphate 15.45
    1-bromopropane 11.61
    gamma-valerolactone 150.96
    n-decanol 20.15
    triethyl phosphate 14.33
    4-methyl-2-pentanol 24.56
    propionitrile 31.37
    vinylene carbonate 60.74
    1,1,2-trichlorotrifluoroethane 114.38
    DMS 28.38
    cumene 6.74
    2-octanol 17.64
    2-hexanone 26.79
    octyl acetate 18.54
    limonene 6.77
    1,2-dimethoxyethane 216.18
    ethyl orthosilicate 12.24
    tributyl phosphate 17.76
    diacetone alcohol 58.47
    N,N-dimethylaniline 33.64
    acrylonitrile 69.82
    aniline 22.03
    1,3-propanediol 201.61
    bromobenzene 7.54
    dibromomethane 21.93
    1,1,2,2-tetrachloroethane 35.16
    2-methyl-cyclohexyl acetate 17.25
    tetrabutyl urea 30.55
    diisobutyl methanol 9.99
    2-phenylethanol 35.64
    styrene 8.91
    dioctyl adipate 21.65
    dimethyl sulfate 66.64
    ethyl butyrate 14.99
    methyl lactate 49.76
    butyl lactate 31.11
    diethyl carbonate 13.59
    propanediol butyl ether 100.2
    triethyl orthoformate 13.84
    p-tert-butyltoluene 5.08
    methyl 4-tert-butylbenzoate 42.83
    morpholine 107.1
    tert-butylamine 37.05
    n-dodecanol 15.1
    dimethoxymethane 135.22
    ethylene carbonate 40.59
    cyrene 86.19
    2-ethoxyethyl acetate 36.69
    2-ethylhexyl acetate 13.06
    1,2,4-trichlorobenzene 17.98
    4-methylpyridine 52.4
    dibutyl ether 15.27
    2,6-dimethyl-4-heptanol 9.99
    DEF 78.16
    dimethyl isosorbide 85.13
    tetrachloroethylene 26.25
    eugenol 62.94
    triacetin 40.21
    span 80 52.9
    1,4-butanediol 128.14
    1,1-dichloroethane 14.8
    2-methyl-1-pentanol 62.29
    methyl formate 203.64
    2-methyl-1-butanol 67.79
    n-decane 1.75
    butyronitrile 33.83
    3,7-dimethyl-1-octanol 25.35
    1-chlorooctane 6.83
    1-chlorotetradecane 3.4
    n-nonane 1.58
    undecane 1.44
    tert-butylcyclohexane 1.09
    cyclooctane 0.67
    cyclopentanol 38.48
    tetrahydropyran 25.2
    tert-amyl methyl ether 23.77
    2,5,8-trioxanonane 145.46
    1-hexene 6.26
    2-isopropoxyethanol 108.14
    2,2,2-trifluoroethanol 124.08
    methyl butyrate 31.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction