Sodium Pyrophosphate

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  • Identifiers

    CAS number
    7722-88-5

    Molecular formula
    Na4O7P2

    SMILES
    [O-]P(=O)([O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 76.69%
    Sweet 18.52%
    Clean 18.08%
    Balsamic 14.08%
    Sour 13.12%
    Alcoholic 12.65%
    Cooling 12.42%
    Savory 12.35%
    Bitter 11.55%
    Fresh 11.41%

     

    Flavor
    Odorless 63.37%
    Sour 25.88%
    Bland 23.52%
    Mild 20.86%
    Very mild 19.45%
    Formyl 18.96%
    Yeast 18.84%
    Mousy 18.78%
    Rotten 18.31%
    Soy 18.17%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    1.21 (strong acid)

    Molecular weight
    265.9 g/mol

    Melting point expt.

    • 1810 °F (NIOSH, 2024)
    • 988 °C
    • 1810 °F

    Boiling point

    • Decomposes (NIOSH, 2024)
    • Decomposes

    Flash point

    • 157.26 ˚C est.

    Solubility expt.

    • 7 % at 77 °F (NIOSH, 2024)
    • Soluble in water. Insoluble in ethanol
    • COLORLESS, MONOCLINIC CRYSTALS; INSOL IN AMMONIA /DECAHYDRATE/
    • INSOL IN ALCOHOL /DECAHYDRATE/
    • SOLUBILITY IN WATER: 3.16 G/100 ML @ 0 °C; 6.23 G/100 ML @ 20 °C; 8.14 G/100 ML @ 25 °C; 21.83 G/100 ML @ 60 °C; 30.04 G/100 ML @ 80 °C /DECAHYDRATE/
    • IN WATER: 2.61 G/100 ML @ 0 °C; 6.7 G/100 ML @ 25 °C; 42.2 G/100 ML @ 100 °C
    • (77 °F): 7%

  • Synonyms

    • Sodium pyrophosphate
    • 7722-88-5
    • TETRASODIUM PYROPHOSPHATE
    • TSPP
    • Phosphotex
    • Tetrasodium diphosphate
    • Diphosphoric acid, tetrasodium salt
    • Sodium diphosphate
    • Victor TSPP
    • Sodium pyrophosphate tetrabasic
    • Caswell No. 847
    • Natrium pyrophosphat
    • Sodium pyrophosphate [USAN]
    • Sodium diphosphate, anhydrous
    • Pyrophosphoric acid tetrasodium salt
    • Sodium phosphate (Na4P2O7)
    • HSDB 854
    • sodium pyrophosphate(V)
    • Sodium diphosphate (Na4P2O7)
    • Sodium pyrophosphate, tetrabasic
    • Sodium pyrophosphate (Na4P2O7)
    • Anhydrous tetrasodium pyrophosphate
    • Tetrasodium pyrophosphate, anhydrous
    • EINECS 231-767-1
    • MFCD00003513
    • NSC 56751
    • EPA Pesticide Chemical Code 076405
    • tetrasodium;phosphonato phosphate
    • DTXSID9042465
    • UNII-O352864B8Z
    • CHEBI:71240
    • NSC-56751
    • Na4P2O7
    • O352864B8Z
    • DTXCID7022465
    • EC 231-767-1
    • Sodium pyrophosphate (USAN)
    • Natrium pyrophosphat [German]
    • SODIUM PYROPHOSPHATE (II)
    • SODIUM PYROPHOSPHATE [II]
    • SODIUM PYROPHOSPHATE (MART.)
    • SODIUM PYROPHOSPHATE [MART.]
    • Tetranatriumpyrophosphat [German]
    • SODIUMPYROPHOSPHATE
    • Tetrasodium pyrophosphate, anhydride
    • Tetrasodium pyrophosphate (anhydrous)
    • tetra sodium pyrophosphate
    • ACCOLINE 126
    • Na4O7P2
    • TETRON (DISPERSANT)
    • Sodium pyrophosphate anydrous
    • Diphosphoric acid sodium salt
    • Sodium pyrophosphate anhydrous
    • Tetrasodium pyrophosphate;PYP
    • DTXCID408842
    • Sodium diphosphate (Na4(P2O7))
    • SODIUM PYROPHOSPHATE [FCC]
    • Tetrasodium pyrophosphate Anhydrous
    • SODIUM PYROPHOSPHATE [HSDB]
    • SODIUM PYROPHOSPHATE [VANDF]
    • tetrasodium (phosphonooxy)phosphonate
    • Tox21_110033
    • SODIUM PYROPHOSPHATE [WHO-DD]
    • TETRASODIUM PYROPHOSPHATE [MI]
    • AKOS015914004
    • AKOS024418778
    • Diphosphoric acid, sodium salt (1:4)
    • FS29954
    • NCGC00013687-01
    • 1004291-85-3
    • CAS-7722-88-5
    • TETRASODIUM DIPHOSPHATE (NA4P2O7)
    • TETRASODIUM PYROPHOSPHATE (NA4P2O7)
    • E 450
    • NS00093593
    • D05873
    • E75941
    • EN300-332889
    • Q418504
    • 231-767-1

  • Applications

    Sodium Pyrophosphate (CAS 7722-88-5) is commonly used as a chelating and water-softening/sequestering agent in formulations across several industries, including detergents and cleaners to soften water and inhibit mineral scaling; in the paper/pulp and textile sectors as a dispersant and anti-scale additive; in coatings and inks to stabilize metal ions and improve pigment dispersion; in plastics and polymers as a processing aid and stabilizer during compounding; and in water treatment and cooling systems as a corrosion inhibitor and scale control agent.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 718.7
    methanol 1379.15
    isopropanol 634.03
    water 1625.93
    ethyl acetate 186.56
    n-propanol 479.45
    acetone 531.27
    n-butanol 369.97
    acetonitrile 293.06
    DMF 1613.42
    toluene 72.45
    isobutanol 323.17
    1,4-dioxane 380.9
    methyl acetate 214.61
    THF 978.04
    2-butanone 292.73
    n-pentanol 218.61
    sec-butanol 404.79
    n-hexane 54.08
    ethylene glycol 566.07
    NMP 682.21
    cyclohexane 50.94
    DMSO 1492.38
    n-butyl acetate 81.14
    n-octanol 116.5
    chloroform 161.79
    n-propyl acetate 122.56
    acetic acid 191.73
    dichloromethane 192.4
    cyclohexanone 185.24
    propylene glycol 437.37
    isopropyl acetate 144.77
    DMAc 1027.11
    2-ethoxyethanol 525.7
    isopentanol 260.07
    n-heptane 43.77
    ethyl formate 201.59
    1,2-dichloroethane 174.95
    n-hexanol 178.25
    2-methoxyethanol 1077.63
    isobutyl acetate 64.8
    tetrachloromethane 71.42
    n-pentyl acetate 67.89
    transcutol 225.34
    n-heptanol 128.73
    ethylbenzene 41.83
    MIBK 190.26
    2-propoxyethanol 457.28
    tert-butanol 639.54
    MTBE 287.8
    2-butoxyethanol 237.13
    propionic acid 186.85
    o-xylene 69.77
    formic acid 412.64
    diethyl ether 419.18
    m-xylene 70.66
    p-xylene 46.1
    chlorobenzene 37.95
    dimethyl carbonate 293.12
    n-octane 22.29
    formamide 677.41
    cyclopentanone 362.67
    2-pentanone 304.98
    anisole 121.69
    cyclopentyl methyl ether 375.91
    gamma-butyrolactone 353.29
    1-methoxy-2-propanol 860.05
    pyridine 147.06
    3-pentanone 236.07
    furfural 237.53
    n-dodecane 16.54
    diethylene glycol 485.07
    diisopropyl ether 133.9
    tert-amyl alcohol 401.48
    acetylacetone 226.88
    n-hexadecane 16.78
    acetophenone 99.96
    methyl propionate 291.92
    isopentyl acetate 58.83
    trichloroethylene 121.79
    n-nonanol 105.61
    cyclohexanol 219.2
    benzyl alcohol 117.16
    2-ethylhexanol 82.4
    isooctanol 87.24
    dipropyl ether 171.19
    1,2-dichlorobenzene 37.86
    ethyl lactate 147.81
    propylene carbonate 156.54
    n-methylformamide 752.8
    2-pentanol 311.91
    n-pentane 95.55
    1-propoxy-2-propanol 290.62
    1-methoxy-2-propyl acetate 147.34
    2-(2-methoxypropoxy) propanol 163.56
    mesitylene 60.6
    ε-caprolactone 147.39
    p-cymene 37.8
    epichlorohydrin 356.69
    1,1,1-trichloroethane 97.12
    2-aminoethanol 634.62
    morpholine-4-carbaldehyde 503.78
    sulfolane 460.36
    2,2,4-trimethylpentane 29.6
    2-methyltetrahydrofuran 385.07
    n-hexyl acetate 79.99
    isooctane 27.47
    2-(2-butoxyethoxy)ethanol 190.12
    sec-butyl acetate 77.19
    tert-butyl acetate 150.82
    decalin 18.66
    glycerin 632.07
    diglyme 307.37
    acrylic acid 165.95
    isopropyl myristate 49.94
    n-butyric acid 175.48
    acetyl acetate 82.88
    di(2-ethylhexyl) phthalate 42.83
    ethyl propionate 147.77
    nitromethane 360.67
    1,2-diethoxyethane 115.92
    benzonitrile 64.28
    trioctyl phosphate 50.28
    1-bromopropane 138.83
    gamma-valerolactone 339.47
    n-decanol 84.66
    triethyl phosphate 65.44
    4-methyl-2-pentanol 167.94
    propionitrile 221.0
    vinylene carbonate 121.7
    1,1,2-trichlorotrifluoroethane 266.1
    DMS 74.46
    cumene 38.63
    2-octanol 93.71
    2-hexanone 146.48
    octyl acetate 66.17
    limonene 50.62
    1,2-dimethoxyethane 599.11
    ethyl orthosilicate 66.49
    tributyl phosphate 44.41
    diacetone alcohol 267.93
    N,N-dimethylaniline 151.7
    acrylonitrile 220.57
    aniline 145.49
    1,3-propanediol 521.41
    bromobenzene 27.56
    dibromomethane 150.33
    1,1,2,2-tetrachloroethane 156.72
    2-methyl-cyclohexyl acetate 63.84
    tetrabutyl urea 79.73
    diisobutyl methanol 68.57
    2-phenylethanol 103.33
    styrene 40.37
    dioctyl adipate 58.97
    dimethyl sulfate 397.89
    ethyl butyrate 89.27
    methyl lactate 320.12
    butyl lactate 82.63
    diethyl carbonate 63.68
    propanediol butyl ether 168.4
    triethyl orthoformate 81.49
    p-tert-butyltoluene 45.56
    methyl 4-tert-butylbenzoate 113.13
    morpholine 504.8
    tert-butylamine 416.66
    n-dodecanol 67.65
    dimethoxymethane 1259.96
    ethylene carbonate 122.82
    cyrene 201.59
    2-ethoxyethyl acetate 78.32
    2-ethylhexyl acetate 47.1
    1,2,4-trichlorobenzene 41.74
    4-methylpyridine 155.11
    dibutyl ether 72.01
    2,6-dimethyl-4-heptanol 68.57
    DEF 394.08
    dimethyl isosorbide 221.49
    tetrachloroethylene 113.35
    eugenol 137.72
    triacetin 71.89
    span 80 110.65
    1,4-butanediol 259.44
    1,1-dichloroethane 145.48
    2-methyl-1-pentanol 143.29
    methyl formate 494.96
    2-methyl-1-butanol 255.35
    n-decane 24.39
    butyronitrile 193.66
    3,7-dimethyl-1-octanol 77.15
    1-chlorooctane 49.68
    1-chlorotetradecane 26.17
    n-nonane 24.9
    undecane 19.49
    tert-butylcyclohexane 21.63
    cyclooctane 29.01
    cyclopentanol 353.31
    tetrahydropyran 280.45
    tert-amyl methyl ether 262.78
    2,5,8-trioxanonane 237.22
    1-hexene 91.77
    2-isopropoxyethanol 319.04
    2,2,2-trifluoroethanol 219.83
    methyl butyrate 158.34

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction