Sodium p-chloro-m-cresol

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  • Identifiers

    CAS number
    15733-22-9

    Molecular formula
    C7H6ClNaO

    SMILES
    CC1=C(C=CC(=C1)[O-])Cl.[Na+]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Phenolic 58.67%
    Sweet 38.6%
    Animal 37.53%
    Woody 36.15%
    Medicinal 33.81%
    Leathery 33.2%
    Smoky 33.18%
    Spicy 30.1%
    Dry 30.03%
    Burnt 29.58%

     

    Flavor
    Phenolic 36.2%
    Bitter 33.05%
    Mild 28.06%
    Medicinal 25.44%
    Meaty 23.46%
    Flat 22.69%
    Very strong 22.09%
    Indole 21.67%
    Creosote 20.73%
    Penetrating 20.69%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    5.56 (weak acid)

    Molecular weight
    164.56 g/mol

    Flash point

    • 73.91 ˚C est.

  • Synonyms

    • Sodium p-chloro-m-cresol
    • Sodium p-chloro-m-cresolate
    • Phenol, 4-chloro-3-methyl-, sodium salt
    • 343KVA8Y38
    • DTXSID7035696
    • PREVENTOL CMK SODIUM SALT
    • 4-CHLORO-M-CRESOL, SODIUM SALT
    • Phenol, 4-chloro-3-methyl-, sodium salt (1:1)
    • RefChem:887768
    • DTXCID5015696
    • SODIUM P-CHLORO-M-CRESOL [INCI]
    • 15733-22-9
    • sodium;4-chloro-3-methylphenolate
    • 2-Chloro-5-hydroxytoluene sodium salt
    • 4-Chloro-m-cresol sodium salt
    • Sodium 4-chloro-3-methylphenolate
    • 3-Methyl-4-chlorophenol, sodium salt
    • Caswell No. 756
    • Chlorocresol sodium
    • Sodium 4-chloro-m-cresolate
    • UNII-343KVA8Y38
    • p-Chloro-m-cresol, sodium salt
    • Sodium 4-chloro-3-methylphenoxide
    • EINECS 239-825-8
    • P-CHLORO-M-CRESOL SODIUM SALT
    • EPA Pesticide Chemical Code 064205
    • SCHEMBL2393522
    • SCHEMBL29600055
    • DPHAGKRZIJHMNL-UHFFFAOYSA-M
    • sodium-4-chloro-3-methylphenolate
    • NS00075793
    • Q27256325
    • 15733-22-9

  • Applications

    Sodium p-chloro-m-cresol is a chlorinated cresol salt that is typically used as an antimicrobial agent and biocide in industrial cleaning, water treatment, and process streams; it is commonly evaluated for use as a preservative or antimicrobial additive in cosmetics and personal care formulations (subject to local regulations); it can be incorporated into coatings and inks to impart antimicrobial properties; it serves as an intermediate in the synthesis of chlorinated phenolic compounds; and it is sometimes considered for use in polymer/plastics formulations as an antimicrobial additive in specialized applications (subject to formulation limits).

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 181.35
    methanol 165.57
    isopropanol 138.42
    water 1.61
    ethyl acetate 363.7
    n-propanol 157.75
    acetone 361.53
    n-butanol 143.65
    acetonitrile 283.14
    DMF 498.04
    toluene 150.87
    isobutanol 114.29
    1,4-dioxane 759.1
    methyl acetate 364.39
    THF 749.4
    2-butanone 352.44
    n-pentanol 150.71
    sec-butanol 143.19
    n-hexane 36.73
    ethylene glycol 52.65
    NMP 530.73
    cyclohexane 37.48
    DMSO 405.36
    n-butyl acetate 248.83
    n-octanol 90.6
    chloroform 656.44
    n-propyl acetate 273.28
    acetic acid 222.83
    dichloromethane 655.56
    cyclohexanone 435.98
    propylene glycol 52.48
    isopropyl acetate 215.52
    DMAc 442.12
    2-ethoxyethanol 310.61
    isopentanol 139.67
    n-heptane 31.84
    ethyl formate 207.97
    1,2-dichloroethane 415.56
    n-hexanol 150.12
    2-methoxyethanol 354.93
    isobutyl acetate 161.71
    tetrachloromethane 137.43
    n-pentyl acetate 166.32
    transcutol 1305.12
    n-heptanol 86.79
    ethylbenzene 105.52
    MIBK 210.51
    2-propoxyethanol 321.99
    tert-butanol 227.47
    MTBE 258.24
    2-butoxyethanol 194.43
    propionic acid 182.27
    o-xylene 121.69
    formic acid 99.06
    diethyl ether 303.11
    m-xylene 123.77
    p-xylene 149.07
    chlorobenzene 236.01
    dimethyl carbonate 182.45
    n-octane 13.74
    formamide 220.74
    cyclopentanone 478.84
    2-pentanone 291.25
    anisole 349.85
    cyclopentyl methyl ether 327.75
    gamma-butyrolactone 599.57
    1-methoxy-2-propanol 291.5
    pyridine 347.68
    3-pentanone 241.45
    furfural 535.05
    n-dodecane 12.12
    diethylene glycol 259.95
    diisopropyl ether 116.87
    tert-amyl alcohol 202.83
    acetylacetone 435.05
    n-hexadecane 14.05
    acetophenone 294.3
    methyl propionate 270.76
    isopentyl acetate 210.02
    trichloroethylene 767.07
    n-nonanol 89.26
    cyclohexanol 154.61
    benzyl alcohol 190.95
    2-ethylhexanol 109.01
    isooctanol 79.77
    dipropyl ether 167.43
    1,2-dichlorobenzene 249.01
    ethyl lactate 126.1
    propylene carbonate 308.42
    n-methylformamide 253.26
    2-pentanol 126.14
    n-pentane 27.69
    1-propoxy-2-propanol 228.12
    1-methoxy-2-propyl acetate 303.38
    2-(2-methoxypropoxy) propanol 284.47
    mesitylene 95.33
    ε-caprolactone 416.97
    p-cymene 79.14
    epichlorohydrin 697.96
    1,1,1-trichloroethane 461.08
    2-aminoethanol 95.72
    morpholine-4-carbaldehyde 707.27
    sulfolane 628.96
    2,2,4-trimethylpentane 22.43
    2-methyltetrahydrofuran 508.55
    n-hexyl acetate 223.55
    isooctane 20.6
    2-(2-butoxyethoxy)ethanol 374.61
    sec-butyl acetate 191.96
    tert-butyl acetate 282.79
    decalin 35.1
    glycerin 99.79
    diglyme 723.31
    acrylic acid 173.04
    isopropyl myristate 112.93
    n-butyric acid 199.25
    acetyl acetate 267.39
    di(2-ethylhexyl) phthalate 95.08
    ethyl propionate 239.12
    nitromethane 571.63
    1,2-diethoxyethane 438.3
    benzonitrile 254.53
    trioctyl phosphate 69.76
    1-bromopropane 216.53
    gamma-valerolactone 680.22
    n-decanol 70.36
    triethyl phosphate 132.0
    4-methyl-2-pentanol 95.18
    propionitrile 205.12
    vinylene carbonate 293.98
    1,1,2-trichlorotrifluoroethane 378.73
    DMS 286.83
    cumene 87.63
    2-octanol 68.99
    2-hexanone 275.75
    octyl acetate 127.55
    limonene 107.3
    1,2-dimethoxyethane 548.64
    ethyl orthosilicate 129.69
    tributyl phosphate 105.28
    diacetone alcohol 291.39
    N,N-dimethylaniline 214.01
    acrylonitrile 267.58
    aniline 184.35
    1,3-propanediol 147.26
    bromobenzene 246.94
    dibromomethane 386.96
    1,1,2,2-tetrachloroethane 516.17
    2-methyl-cyclohexyl acetate 182.83
    tetrabutyl urea 125.3
    diisobutyl methanol 81.18
    2-phenylethanol 192.91
    styrene 140.47
    dioctyl adipate 171.18
    dimethyl sulfate 282.29
    ethyl butyrate 217.35
    methyl lactate 143.66
    butyl lactate 132.39
    diethyl carbonate 166.19
    propanediol butyl ether 181.08
    triethyl orthoformate 161.89
    p-tert-butyltoluene 81.54
    methyl 4-tert-butylbenzoate 232.15
    morpholine 639.31
    tert-butylamine 145.63
    n-dodecanol 57.03
    dimethoxymethane 410.94
    ethylene carbonate 248.63
    cyrene 274.32
    2-ethoxyethyl acetate 301.54
    2-ethylhexyl acetate 182.17
    1,2,4-trichlorobenzene 283.09
    4-methylpyridine 362.67
    dibutyl ether 155.58
    2,6-dimethyl-4-heptanol 81.18
    DEF 331.84
    dimethyl isosorbide 502.36
    tetrachloroethylene 337.58
    eugenol 244.55
    triacetin 296.93
    span 80 203.38
    1,4-butanediol 78.74
    1,1-dichloroethane 406.25
    2-methyl-1-pentanol 153.94
    methyl formate 212.68
    2-methyl-1-butanol 129.84
    n-decane 18.21
    butyronitrile 189.83
    3,7-dimethyl-1-octanol 106.99
    1-chlorooctane 74.71
    1-chlorotetradecane 37.53
    n-nonane 16.81
    undecane 14.47
    tert-butylcyclohexane 35.01
    cyclooctane 17.34
    cyclopentanol 167.86
    tetrahydropyran 456.65
    tert-amyl methyl ether 212.41
    2,5,8-trioxanonane 529.76
    1-hexene 100.99
    2-isopropoxyethanol 255.76
    2,2,2-trifluoroethanol 138.05
    methyl butyrate 272.3

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction