Sodium mercaptopyruvate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    10255-67-1

    Molecular formula
    C3H3NaO3S

    SMILES
    C(C(=O)C(=O)[O-])S.[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sulfurous 62.95%
    Meaty 47.47%
    Odorless 44.18%
    Roasted 38.27%
    Savory 37.72%
    Burnt 31.62%
    Cooked 29.85%
    Caramellic 25.46%
    Cheesy 24.27%
    Onion 24.25%

     

    Flavor
    Odorless 49.64%
    Nutty 32.07%
    Very mild 31.63%
    Caramellic 26.47%
    Sour 25.39%
    Musty 22.51%
    Cooked 21.67%
    Mild 21.26%
    Yeast 21.15%
    Bread 21.14%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    4.75 (weak acid)

    Molecular weight
    142.11 g/mol

    Flash point

    • 90.17 ˚C est.

    Solubility expt.

    • soluble in water at 200 g/l at 20oC, white petrolatum at <100 g/kg at 20oC

  • Synonyms

    • Sodium mercaptopyruvate
    • 10255-67-1
    • Sodium 3-mercaptopyruvate
    • sodium 2-oxo-3-sulfanylpropanoate
    • Propanoic acid, 3-mercapto-2-oxo-, sodium salt (1:1)
    • sodium 3-mercapto-2-oxopropanoate
    • UNII-1734XUO14Z
    • 3-Mercapto-2-oxopropionic acid sodium salt
    • 1734XUO14Z
    • sodium;2-oxo-3-sulfanylpropanoate
    • EINECS 233-594-7
    • Propanoic acid, 3-mercapto-2-oxo-, monosodium salt
    • FEMA NO. 3901
    • DTXSID20145265
    • SODIUM 3-MERCAPTO-OXOPROPIONATE
    • SODIUM 3-MERCAPTOPYRUVATE [FHFI]
    • PYRUVIC ACID, MERCAPTO-, SODIUM SALT
    • Mercaptopyruvic acid sodium salt
    • SCHEMBL1323456
    • DTXCID1067756
    • sodium3-mercapto-2-oxopropanoate
    • CODUSAVZTZYYDD-UHFFFAOYSA-M
    • AKOS015911187
    • AKOS025293979
    • HY-W170255
    • FS145294
    • CS-0231406
    • NS00021451
    • Sodium mercaptopyruvate, 90%, technical grade
    • G86174
    • EN300-1082486
    • Q27251859

  • Applications

    Sodium mercaptopyruvate is considered a versatile building block for organic synthesis, enabling the formation of thiol-containing derivatives such as thioethers and thioesters; in pharmaceutical and medicinal chemistry, it is often regarded as a building block for thiol-bearing fragments; in biochemical and enzymology research, it serves as a substrate for sulfurtransferase enzyme systems (e.g., 3-mercaptopyruvate sulfurtransferase) and as a tool for studies on hydrogen sulfide biology; and in polymer and materials science, it is explored as a thiol-functional building block or precursor for sulfur-containing polymers and crosslinking applications in materials.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 201.14
    methanol 418.83
    isopropanol 98.37
    water 58.39
    ethyl acetate 86.83
    n-propanol 105.02
    acetone 310.81
    n-butanol 85.43
    acetonitrile 115.54
    DMF 937.17
    toluene 14.5
    isobutanol 52.5
    1,4-dioxane 121.0
    methyl acetate 149.49
    THF 119.33
    2-butanone 142.6
    n-pentanol 74.76
    sec-butanol 76.76
    n-hexane 5.63
    ethylene glycol 208.43
    NMP 528.94
    cyclohexane 7.32
    DMSO 1021.34
    n-butyl acetate 50.03
    n-octanol 69.5
    chloroform 43.76
    n-propyl acetate 59.36
    acetic acid 296.3
    dichloromethane 85.04
    cyclohexanone 118.71
    propylene glycol 103.03
    isopropyl acetate 45.18
    DMAc 547.65
    2-ethoxyethanol 246.29
    isopentanol 63.85
    n-heptane 7.29
    ethyl formate 111.44
    1,2-dichloroethane 97.86
    n-hexanol 57.7
    2-methoxyethanol 456.55
    isobutyl acetate 18.17
    tetrachloromethane 8.62
    n-pentyl acetate 66.84
    transcutol 763.11
    n-heptanol 52.74
    ethylbenzene 13.57
    MIBK 56.02
    2-propoxyethanol 151.65
    tert-butanol 96.69
    MTBE 44.34
    2-butoxyethanol 123.15
    propionic acid 132.55
    o-xylene 21.01
    formic acid 459.58
    diethyl ether 66.09
    m-xylene 16.51
    p-xylene 15.3
    chlorobenzene 25.98
    dimethyl carbonate 69.09
    n-octane 5.85
    formamide 679.33
    cyclopentanone 135.74
    2-pentanone 111.61
    anisole 41.7
    cyclopentyl methyl ether 47.47
    gamma-butyrolactone 182.23
    1-methoxy-2-propanol 247.57
    pyridine 101.01
    3-pentanone 81.58
    furfural 246.52
    n-dodecane 5.62
    diethylene glycol 242.23
    diisopropyl ether 17.29
    tert-amyl alcohol 81.94
    acetylacetone 170.91
    n-hexadecane 5.95
    acetophenone 80.19
    methyl propionate 104.24
    isopentyl acetate 35.38
    trichloroethylene 134.19
    n-nonanol 61.23
    cyclohexanol 56.85
    benzyl alcohol 73.85
    2-ethylhexanol 32.11
    isooctanol 36.24
    dipropyl ether 30.14
    1,2-dichlorobenzene 35.36
    ethyl lactate 56.42
    propylene carbonate 74.86
    n-methylformamide 422.87
    2-pentanol 58.79
    n-pentane 8.46
    1-propoxy-2-propanol 98.23
    1-methoxy-2-propyl acetate 67.78
    2-(2-methoxypropoxy) propanol 141.36
    mesitylene 14.0
    ε-caprolactone 111.08
    p-cymene 14.17
    epichlorohydrin 154.59
    1,1,1-trichloroethane 26.98
    2-aminoethanol 184.96
    morpholine-4-carbaldehyde 421.28
    sulfolane 320.08
    2,2,4-trimethylpentane 3.48
    2-methyltetrahydrofuran 66.32
    n-hexyl acetate 89.28
    isooctane 3.17
    2-(2-butoxyethoxy)ethanol 239.58
    sec-butyl acetate 25.93
    tert-butyl acetate 50.48
    decalin 4.28
    glycerin 202.96
    diglyme 336.34
    acrylic acid 194.11
    isopropyl myristate 35.4
    n-butyric acid 112.17
    acetyl acetate 63.54
    di(2-ethylhexyl) phthalate 43.19
    ethyl propionate 45.82
    nitromethane 663.7
    1,2-diethoxyethane 119.14
    benzonitrile 62.61
    trioctyl phosphate 34.44
    1-bromopropane 31.01
    gamma-valerolactone 243.87
    n-decanol 48.23
    triethyl phosphate 24.08
    4-methyl-2-pentanol 32.72
    propionitrile 55.67
    vinylene carbonate 85.9
    1,1,2-trichlorotrifluoroethane 201.89
    DMS 74.84
    cumene 11.96
    2-octanol 41.34
    2-hexanone 70.14
    octyl acetate 52.22
    limonene 21.42
    1,2-dimethoxyethane 262.46
    ethyl orthosilicate 20.33
    tributyl phosphate 37.47
    diacetone alcohol 126.99
    N,N-dimethylaniline 50.84
    acrylonitrile 122.48
    aniline 41.5
    1,3-propanediol 203.39
    bromobenzene 17.77
    dibromomethane 47.06
    1,1,2,2-tetrachloroethane 94.81
    2-methyl-cyclohexyl acetate 32.11
    tetrabutyl urea 79.71
    diisobutyl methanol 22.18
    2-phenylethanol 60.83
    styrene 18.12
    dioctyl adipate 58.72
    dimethyl sulfate 161.22
    ethyl butyrate 36.75
    methyl lactate 116.48
    butyl lactate 73.99
    diethyl carbonate 25.01
    propanediol butyl ether 169.15
    triethyl orthoformate 25.67
    p-tert-butyltoluene 13.61
    methyl 4-tert-butylbenzoate 94.25
    morpholine 152.97
    tert-butylamine 45.88
    n-dodecanol 37.12
    dimethoxymethane 251.65
    ethylene carbonate 57.68
    cyrene 112.41
    2-ethoxyethyl acetate 113.26
    2-ethylhexyl acetate 26.59
    1,2,4-trichlorobenzene 44.45
    4-methylpyridine 80.17
    dibutyl ether 45.18
    2,6-dimethyl-4-heptanol 22.18
    DEF 226.06
    dimethyl isosorbide 157.04
    tetrachloroethylene 90.04
    eugenol 120.52
    triacetin 108.09
    span 80 125.62
    1,4-butanediol 108.45
    1,1-dichloroethane 35.69
    2-methyl-1-pentanol 54.37
    methyl formate 316.79
    2-methyl-1-butanol 55.0
    n-decane 8.24
    butyronitrile 49.19
    3,7-dimethyl-1-octanol 47.65
    1-chlorooctane 25.4
    1-chlorotetradecane 12.81
    n-nonane 8.06
    undecane 6.65
    tert-butylcyclohexane 3.49
    cyclooctane 3.88
    cyclopentanol 59.24
    tetrahydropyran 54.43
    tert-amyl methyl ether 42.58
    2,5,8-trioxanonane 256.2
    1-hexene 16.3
    2-isopropoxyethanol 122.88
    2,2,2-trifluoroethanol 153.33
    methyl butyrate 76.29

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction