Sodium mannose 6-phosphate

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  • Identifiers

    CAS number
    70442-25-0

    Molecular formula
    C6H12NaO9P

    SMILES
    C([C@H]([C@H]([C@@H]([C@@H](C=O)O)O)O)O)OP(=O)(O)[O-].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 77.8%
    Sweet 29.02%
    Savory 20.15%
    Clean 17.51%
    Buttery 16.94%
    Milky 16.11%
    Caramellic 15.88%
    Bitter 15.78%
    Alcoholic 15.2%
    Cooling 14.1%

     

    Flavor
    Odorless 73.19%
    Very mild 33.35%
    Sweet-like 27.19%
    Bland 26.17%
    Mild 25.74%
    Yeast 22.01%
    Sour 20.75%
    Caramellic 20.57%
    Very slight 19.96%
    Formyl 19.07%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.31 (weak acid)

    Molecular weight
    282.12 g/mol

    Flash point

    • 274.57 ˚C est.

  • Synonyms

    • 70442-25-0
    • Sodium mannose 6-phosphate
    • Sodium D-mannose 6-phosphate
    • UNII-R5Q39V6076
    • D-Mannose, 6-(dihydrogen phosphate), sodium salt (1:1)
    • R5Q39V6076
    • D-Mannose, 6-(dihydrogen phosphate), monosodium salt
    • RefChem:183971
    • D-Mannose-6-phosphate sodium salt
    • D-Mannose 6-phosphate sodium salt
    • sodium;[(2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl] hydrogen phosphate
    • Sodium (2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl hydrogenphosphate
    • D-MANNOSE 6-PHOSPHATE MONOSODIUM SALT
    • MSK2373Na
    • D-Mannose-6-phosphate sodium
    • orb2941240
    • SCHEMBL6942800
    • OBHLNVXMRZXIII-MVNLRXSJSA-M
    • DTXSID001021526
    • MM06705
    • MONOSODIUM D-MANNOSE 6-PHOSPHATE
    • DB-254580
    • Q27287827
    • sodium;[(2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxo-hexyl] hydrogen phosphate
    • 70442-25-0

  • Applications

    Sodium mannose 6-phosphate (CAS 70442-25-0) is primarily used as a biochemical reagent in carbohydrate biology and glycosylation studies; in biotech and pharmaceutical research it serves as a substrate for enzymatic reactions and as an intermediate in the synthesis of glycoproteins and glycoconjugates; it is used in cell-free systems and analytical assays to probe mannose-6-phosphate pathways and lysosomal targeting; it may also be used as a reference substrate in carbohydrate chemistry to construct defined glycan structures; and it is commonly evaluated for glycoengineering workflows in research settings.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.54
    methanol 6.67
    isopropanol 0.94
    water 496.71
    ethyl acetate 0.4
    n-propanol 0.87
    acetone 2.08
    n-butanol 0.61
    acetonitrile 0.48
    DMF 54.86
    toluene 0.42
    isobutanol 0.4
    1,4-dioxane 1.93
    methyl acetate 0.43
    THF 2.46
    2-butanone 0.66
    n-pentanol 0.32
    sec-butanol 0.72
    n-hexane 0.09
    ethylene glycol 38.25
    NMP 43.01
    cyclohexane 0.6
    DMSO 129.63
    n-butyl acetate 0.32
    n-octanol 0.53
    chloroform 0.06
    n-propyl acetate 0.2
    acetic acid 5.38
    dichloromethane 0.11
    cyclohexanone 1.51
    propylene glycol 13.81
    isopropyl acetate 0.38
    DMAc 29.58
    2-ethoxyethanol 7.36
    isopentanol 0.46
    n-heptane 0.44
    ethyl formate 0.63
    1,2-dichloroethane 0.2
    n-hexanol 0.77
    2-methoxyethanol 25.76
    isobutyl acetate 0.06
    tetrachloromethane 0.1
    n-pentyl acetate 0.32
    transcutol 7.14
    n-heptanol 0.83
    ethylbenzene 0.17
    MIBK 0.63
    2-propoxyethanol 5.72
    tert-butanol 1.91
    MTBE 0.43
    2-butoxyethanol 3.03
    propionic acid 1.41
    o-xylene 0.77
    formic acid 92.05
    diethyl ether 0.57
    m-xylene 0.5
    p-xylene 0.17
    chlorobenzene 0.07
    dimethyl carbonate 2.44
    n-octane 0.19
    formamide 87.08
    cyclopentanone 2.48
    2-pentanone 0.91
    anisole 0.37
    cyclopentyl methyl ether 1.92
    gamma-butyrolactone 2.89
    1-methoxy-2-propanol 13.37
    pyridine 0.87
    3-pentanone 0.82
    furfural 4.8
    n-dodecane 0.09
    diethylene glycol 22.71
    diisopropyl ether 0.33
    tert-amyl alcohol 1.38
    acetylacetone 2.62
    n-hexadecane 0.1
    acetophenone 0.63
    methyl propionate 1.06
    isopentyl acetate 0.24
    trichloroethylene 0.18
    n-nonanol 0.55
    cyclohexanol 1.53
    benzyl alcohol 0.63
    2-ethylhexanol 0.45
    isooctanol 0.49
    dipropyl ether 0.88
    1,2-dichlorobenzene 0.09
    ethyl lactate 1.36
    propylene carbonate 0.87
    n-methylformamide 16.09
    2-pentanol 0.63
    n-pentane 0.16
    1-propoxy-2-propanol 3.51
    1-methoxy-2-propyl acetate 1.31
    2-(2-methoxypropoxy) propanol 3.17
    mesitylene 0.51
    ε-caprolactone 1.13
    p-cymene 0.34
    epichlorohydrin 0.87
    1,1,1-trichloroethane 0.07
    2-aminoethanol 17.44
    morpholine-4-carbaldehyde 22.83
    sulfolane 17.31
    2,2,4-trimethylpentane 0.08
    2-methyltetrahydrofuran 1.0
    n-hexyl acetate 0.38
    isooctane 0.05
    2-(2-butoxyethoxy)ethanol 4.35
    sec-butyl acetate 0.13
    tert-butyl acetate 0.78
    decalin 0.1
    glycerin 77.35
    diglyme 7.8
    acrylic acid 3.09
    isopropyl myristate 0.21
    n-butyric acid 0.92
    acetyl acetate 0.44
    di(2-ethylhexyl) phthalate 0.3
    ethyl propionate 0.3
    nitromethane 8.05
    1,2-diethoxyethane 0.72
    benzonitrile 0.2
    trioctyl phosphate 0.33
    1-bromopropane 0.08
    gamma-valerolactone 5.97
    n-decanol 0.46
    triethyl phosphate 0.45
    4-methyl-2-pentanol 0.35
    propionitrile 0.25
    vinylene carbonate 0.76
    1,1,2-trichlorotrifluoroethane 5.83
    DMS 0.52
    cumene 0.14
    2-octanol 0.47
    2-hexanone 0.23
    octyl acetate 0.32
    limonene 0.56
    1,2-dimethoxyethane 4.59
    ethyl orthosilicate 0.43
    tributyl phosphate 0.25
    diacetone alcohol 4.38
    N,N-dimethylaniline 0.77
    acrylonitrile 0.57
    aniline 0.82
    1,3-propanediol 9.55
    bromobenzene 0.05
    dibromomethane 0.08
    1,1,2,2-tetrachloroethane 0.31
    2-methyl-cyclohexyl acetate 0.34
    tetrabutyl urea 0.89
    diisobutyl methanol 0.46
    2-phenylethanol 0.78
    styrene 0.13
    dioctyl adipate 0.31
    dimethyl sulfate 8.73
    ethyl butyrate 0.42
    methyl lactate 7.22
    butyl lactate 0.9
    diethyl carbonate 0.27
    propanediol butyl ether 3.78
    triethyl orthoformate 0.56
    p-tert-butyltoluene 0.39
    methyl 4-tert-butylbenzoate 1.71
    morpholine 3.26
    tert-butylamine 0.76
    n-dodecanol 0.37
    dimethoxymethane 11.34
    ethylene carbonate 0.53
    cyrene 6.28
    2-ethoxyethyl acetate 0.59
    2-ethylhexyl acetate 0.19
    1,2,4-trichlorobenzene 0.13
    4-methylpyridine 0.63
    dibutyl ether 0.3
    2,6-dimethyl-4-heptanol 0.46
    DEF 4.06
    dimethyl isosorbide 4.8
    tetrachloroethylene 0.38
    eugenol 2.04
    triacetin 0.8
    span 80 2.4
    1,4-butanediol 3.3
    1,1-dichloroethane 0.07
    2-methyl-1-pentanol 0.23
    methyl formate 8.64
    2-methyl-1-butanol 0.48
    n-decane 0.16
    butyronitrile 0.19
    3,7-dimethyl-1-octanol 0.31
    1-chlorooctane 0.18
    1-chlorotetradecane 0.1
    n-nonane 0.17
    undecane 0.12
    tert-butylcyclohexane 0.05
    cyclooctane 0.47
    cyclopentanol 1.8
    tetrahydropyran 0.76
    tert-amyl methyl ether 0.68
    2,5,8-trioxanonane 7.44
    1-hexene 0.08
    2-isopropoxyethanol 2.47
    2,2,2-trifluoroethanol 8.66
    methyl butyrate 0.39

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction