Sodium Malate

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  • Identifiers

    CAS number
    676-46-0

    Molecular formula
    C4H4Na2O5

    SMILES
    C(C(C(=O)[O-])O)C(=O)[O-].[Na+].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 67.41%
    Sweet 37.77%
    Caramellic 31.2%
    Buttery 28.2%
    Sour 25.34%
    Creamy 20.23%
    Milky 19.99%
    Fatty 19.6%
    Burnt 19.57%
    Sharp 18.57%

     

    Flavor
    Odorless 68.13%
    Very mild 35.22%
    Sour 28.18%
    Mild 26.29%
    Caramellic 22.55%
    Sweet-like 21.97%
    Bland 21.79%
    Yeast 21.48%
    Faint 19.05%
    Acetoin 18.91%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    0.9 (strong acid)

    Molecular weight
    178.05 g/mol

    Flash point

    • 151.99 ˚C est.

    Solubility expt.

    • Freely soluble in water

  • Synonyms

    • Sodium malate
    • Disodium malate
    • 676-46-0
    • DL-Malic acid disodium salt
    • Disodium DL-malate
    • SODIUM DL-MALATE
    • 22798-10-3
    • Sodium DL-maleate
    • Natriummalat
    • Natriummalat [German]
    • disodium 2-hydroxybutanedioate
    • disodium;2-hydroxybutanedioate
    • Butanedioic acid, hydroxy-, disodium salt
    • malic acid sodium salt
    • CCRIS 7317
    • Sodium 2-hydroxysuccinate
    • EINECS 211-627-6
    • 2EFF9N315F
    • INS NO.350(II)
    • DTXSID7046831
    • INS-350(II)
    • E-350(II)
    • 63474-37-3
    • BUTANEDIOIC ACID, 2-HYDROXY-, SODIUM SALT (1:2)
    • L-HYDROXYBUTANEDIOICACIDDISODIUMSALT
    • DTXCID5026831
    • Malic acid, disodium salt
    • CHEMBL182856
    • Butanedioic acid, 2-hydroxy-, sodium salt (1:2), (2S)-
    • CAS-676-46-0
    • Sodium D,L-malate
    • NCGC00181053-01
    • Disodium2-hydroxybutanedioate
    • UNII-2EFF9N315F
    • 58214-38-3
    • Sodium salt of malic acid
    • D,L-Malate sodium hydrate
    • SODIUM MALATE, DL-
    • DL-Apple Acid Disodium Salt
    • SODIUM MALATE [INCI]
    • SCHEMBL123089
    • DL-Hydroxysuccinic Acid Sodium
    • (+/-)-SODIUM MALATE
    • CHEBI:91260
    • SODIUM MALATE, (+/-)-
    • NCA47437
    • Tox21_112699
    • MFCD00012466
    • DL-Hydroxysuccinic acid disodium salt
    • DL-2-Hydroxysuccinic acid sodium salt
    • Tox21_112699_1
    • DL-Malic acid sodium;Sodium DL-Malate
    • FH69982
    • FM47038
    • NCGC00043225-04
    • E350
    • Butanedioic acid, 2-hydroxy-, sodium salt
    • DB-042411
    • DB-066312
    • M0026
    • NS00080025
    • C20341
    • EN300-7699061
    • Q836788
    • 211-627-6
    • 866-020-4

  • Applications

    Sodium malate (CAS 676-46-0) is the sodium salt of malic acid, used primarily as an acidulant and pH buffer in foods and beverages, helping to balance sourness and stabilize formulations; in cosmetics and personal care, it functions as a chelating agent and pH adjuster to stabilize products and reduce metal-catalyzed degradation; in cleaning and household products, it serves as a water-softening/chelating agent to sequester metals and improve cleaning efficiency; in industrial manufacturing, it can be an intermediate or starting material in organic synthesis and is also used as a chelating agent in process water treatment; in pharmaceuticals, it may serve as a buffering agent or excipient in certain formulations, subject to regulatory limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1115.63
    methanol 2069.18
    isopropanol 640.37
    water 1363.45
    ethyl acetate 99.12
    n-propanol 637.95
    acetone 668.63
    n-butanol 420.74
    acetonitrile 324.05
    DMF 2412.01
    toluene 36.86
    isobutanol 337.57
    1,4-dioxane 604.46
    methyl acetate 241.73
    THF 547.34
    2-butanone 332.65
    n-pentanol 282.34
    sec-butanol 421.38
    n-hexane 21.29
    ethylene glycol 829.68
    NMP 665.9
    cyclohexane 29.7
    DMSO 2719.46
    n-butyl acetate 32.39
    n-octanol 78.07
    chloroform 32.44
    n-propyl acetate 73.11
    acetic acid 304.86
    dichloromethane 109.66
    cyclohexanone 147.78
    propylene glycol 394.49
    isopropyl acetate 52.87
    DMAc 1335.03
    2-ethoxyethanol 998.72
    isopentanol 276.38
    n-heptane 13.95
    ethyl formate 197.64
    1,2-dichloroethane 168.96
    n-hexanol 90.65
    2-methoxyethanol 1630.93
    isobutyl acetate 19.47
    tetrachloromethane 9.86
    n-pentyl acetate 31.71
    transcutol 567.54
    n-heptanol 62.08
    ethylbenzene 32.46
    MIBK 80.76
    2-propoxyethanol 255.75
    tert-butanol 672.48
    MTBE 249.23
    2-butoxyethanol 156.57
    propionic acid 185.25
    o-xylene 49.34
    formic acid 870.26
    diethyl ether 278.0
    m-xylene 26.54
    p-xylene 31.05
    chlorobenzene 15.57
    dimethyl carbonate 128.69
    n-octane 8.72
    formamide 1523.1
    cyclopentanone 226.22
    2-pentanone 194.91
    anisole 152.32
    cyclopentyl methyl ether 152.05
    gamma-butyrolactone 227.39
    1-methoxy-2-propanol 647.28
    pyridine 176.38
    3-pentanone 136.52
    furfural 241.23
    n-dodecane 6.71
    diethylene glycol 386.61
    diisopropyl ether 45.23
    tert-amyl alcohol 471.04
    acetylacetone 150.23
    n-hexadecane 6.86
    acetophenone 96.1
    methyl propionate 147.46
    isopentyl acetate 24.35
    trichloroethylene 81.7
    n-nonanol 68.23
    cyclohexanol 151.5
    benzyl alcohol 142.38
    2-ethylhexanol 37.19
    isooctanol 42.84
    dipropyl ether 65.46
    1,2-dichlorobenzene 15.65
    ethyl lactate 64.9
    propylene carbonate 63.11
    n-methylformamide 1142.74
    2-pentanol 204.8
    n-pentane 37.6
    1-propoxy-2-propanol 126.76
    1-methoxy-2-propyl acetate 46.25
    2-(2-methoxypropoxy) propanol 151.5
    mesitylene 20.39
    ε-caprolactone 122.66
    p-cymene 14.49
    epichlorohydrin 373.3
    1,1,1-trichloroethane 27.86
    2-aminoethanol 934.29
    morpholine-4-carbaldehyde 777.42
    sulfolane 352.27
    2,2,4-trimethylpentane 9.75
    2-methyltetrahydrofuran 277.74
    n-hexyl acetate 45.81
    isooctane 5.65
    2-(2-butoxyethoxy)ethanol 219.78
    sec-butyl acetate 32.6
    tert-butyl acetate 63.5
    decalin 9.38
    glycerin 521.96
    diglyme 474.67
    acrylic acid 192.81
    isopropyl myristate 22.06
    n-butyric acid 117.52
    acetyl acetate 38.74
    di(2-ethylhexyl) phthalate 24.19
    ethyl propionate 67.74
    nitromethane 695.37
    1,2-diethoxyethane 135.1
    benzonitrile 50.57
    trioctyl phosphate 20.27
    1-bromopropane 83.68
    gamma-valerolactone 367.74
    n-decanol 54.38
    triethyl phosphate 23.49
    4-methyl-2-pentanol 78.04
    propionitrile 181.03
    vinylene carbonate 70.64
    1,1,2-trichlorotrifluoroethane 189.54
    DMS 38.9
    cumene 23.02
    2-octanol 44.56
    2-hexanone 115.5
    octyl acetate 33.37
    limonene 21.15
    1,2-dimethoxyethane 1139.98
    ethyl orthosilicate 23.03
    tributyl phosphate 21.12
    diacetone alcohol 167.72
    N,N-dimethylaniline 138.23
    acrylonitrile 226.25
    aniline 98.82
    1,3-propanediol 779.93
    bromobenzene 11.1
    dibromomethane 64.65
    1,1,2,2-tetrachloroethane 78.4
    2-methyl-cyclohexyl acetate 24.61
    tetrabutyl urea 50.76
    diisobutyl methanol 25.82
    2-phenylethanol 60.1
    styrene 37.95
    dioctyl adipate 34.88
    dimethyl sulfate 238.05
    ethyl butyrate 34.63
    methyl lactate 147.15
    butyl lactate 36.98
    diethyl carbonate 24.89
    propanediol butyl ether 147.27
    triethyl orthoformate 30.18
    p-tert-butyltoluene 14.65
    methyl 4-tert-butylbenzoate 68.07
    morpholine 718.09
    tert-butylamine 311.43
    n-dodecanol 42.08
    dimethoxymethane 884.97
    ethylene carbonate 62.62
    cyrene 144.57
    2-ethoxyethyl acetate 55.16
    2-ethylhexyl acetate 17.52
    1,2,4-trichlorobenzene 19.47
    4-methylpyridine 151.98
    dibutyl ether 56.66
    2,6-dimethyl-4-heptanol 25.82
    DEF 385.1
    dimethyl isosorbide 137.49
    tetrachloroethylene 63.85
    eugenol 84.66
    triacetin 50.52
    span 80 76.19
    1,4-butanediol 429.0
    1,1-dichloroethane 63.79
    2-methyl-1-pentanol 186.59
    methyl formate 713.1
    2-methyl-1-butanol 280.83
    n-decane 10.44
    butyronitrile 147.08
    3,7-dimethyl-1-octanol 50.74
    1-chlorooctane 23.11
    1-chlorotetradecane 11.33
    n-nonane 10.83
    undecane 8.33
    tert-butylcyclohexane 6.93
    cyclooctane 13.48
    cyclopentanol 203.61
    tetrahydropyran 259.43
    tert-amyl methyl ether 193.77
    2,5,8-trioxanonane 350.94
    1-hexene 51.07
    2-isopropoxyethanol 403.17
    2,2,2-trifluoroethanol 199.45
    methyl butyrate 106.44

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction