Sodium lauroyl glycinate

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  • Identifiers

    CAS number
    18777-32-7

    Molecular formula
    C14H26NNaO3

    SMILES
    CCCCCCCCCCCC(=O)NCC(=O)[O-].[Na+]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 40.89%
    Savory 36.1%
    Fatty 33.14%
    Meaty 32.65%
    Waxy 27.7%
    Milky 24.62%
    Cooling 24.55%
    Oily 24.04%
    Citrus 23.93%
    Herbal 22.15%

     

    Flavor
    Odorless 38.19%
    Bland 32.85%
    Mild 30.14%
    Herbal 27.18%
    Fatty 24.12%
    Faint 22.64%
    Slightly waxy 21.31%
    Bay oil 20.84%
    Waxy 20.61%
    Cultured dairy 20.22%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.12 (weak acid)

    Molecular weight
    279.35 g/mol

    Flash point

    • 190.0 ˚C est.

  • Synonyms

    • Sodium lauroyl glycinate
    • Sodium N-lauroylglycine
    • Sodium dodecanoylglycinate
    • N-Lauroylglycine sodium salt
    • 18777-32-7
    • Glycine, N-lauroyl-, sodium salt
    • UNII-L54QIO80PN
    • L54QIO80PN
    • Glycine, N-lauroyl-, monosodium salt
    • Glycine, N-(1-oxododecyl)-, sodium salt (1:1)
    • DTXSID90172088
    • RefChem:183962
    • DTXCID5094579
    • SODIUM LAUROYL GLYCINATE [INCI]
    • Sodium cocoyl glycinate
    • 90387-74-9
    • sodium;2-(dodecanoylamino)acetate
    • EINECS 291-350-5
    • sodium n-lauroylglycinate
    • Sodium dodecanamidoacetate
    • UNII-XLU9KH03XM
    • XLU9KH03XM
    • SCHEMBL452024
    • AKOS024351953
    • FS41806
    • 2-(dodecanoylamino)acetic acid, sodium salt
    • ST50976878
    • A937121
    • Q27282720
    • 18777-32-7

  • Applications

    Sodium lauroyl glycinate (CAS 18777-32-7) is a mild amino acid-based surfactant widely used in cosmetics and personal care as a cleansing agent, foaming booster, and conditioning component in shampoos, facial cleansers, and body washes; it is also employed in household cleaning products as a mild detergent and emulsifier for surface and material cleanliness; in pharmaceutical applications it may serve as an excipient or surfactant in topical formulations; and in industrial manufacturing it functions as an emulsifier and wetting agent in coating-formulation systems and specialty cleaners, aiding dispersion and formulation stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 121.56
    methanol 196.17
    isopropanol 84.22
    water 0.06
    ethyl acetate 75.29
    n-propanol 75.56
    acetone 125.07
    n-butanol 60.39
    acetonitrile 47.3
    DMF 338.87
    toluene 24.07
    isobutanol 53.99
    1,4-dioxane 96.82
    methyl acetate 71.53
    THF 300.36
    2-butanone 104.53
    n-pentanol 62.89
    sec-butanol 61.95
    n-hexane 3.24
    ethylene glycol 14.6
    NMP 342.45
    cyclohexane 4.27
    DMSO 697.9
    n-butyl acetate 100.38
    n-octanol 22.93
    chloroform 125.64
    n-propyl acetate 103.72
    acetic acid 98.61
    dichloromethane 155.19
    cyclohexanone 214.46
    propylene glycol 36.02
    isopropyl acetate 81.6
    DMAc 414.35
    2-ethoxyethanol 164.87
    isopentanol 71.29
    n-heptane 1.46
    ethyl formate 57.86
    1,2-dichloroethane 135.84
    n-hexanol 44.06
    2-methoxyethanol 200.07
    isobutyl acetate 72.96
    tetrachloromethane 17.98
    n-pentyl acetate 74.78
    transcutol 533.41
    n-heptanol 24.04
    ethylbenzene 22.62
    MIBK 89.67
    2-propoxyethanol 136.62
    tert-butanol 129.34
    MTBE 87.19
    2-butoxyethanol 87.25
    propionic acid 67.33
    o-xylene 29.82
    formic acid 41.52
    diethyl ether 45.82
    m-xylene 24.41
    p-xylene 33.35
    chlorobenzene 44.0
    dimethyl carbonate 27.62
    n-octane 1.17
    formamide 82.59
    cyclopentanone 258.45
    2-pentanone 97.01
    anisole 65.14
    cyclopentyl methyl ether 101.0
    gamma-butyrolactone 248.71
    1-methoxy-2-propanol 162.95
    pyridine 106.93
    3-pentanone 59.88
    furfural 223.92
    n-dodecane 1.09
    diethylene glycol 94.56
    diisopropyl ether 17.95
    tert-amyl alcohol 100.4
    acetylacetone 160.63
    n-hexadecane 1.28
    acetophenone 92.94
    methyl propionate 60.43
    isopentyl acetate 110.48
    trichloroethylene 219.68
    n-nonanol 22.48
    cyclohexanol 61.26
    benzyl alcohol 63.62
    2-ethylhexanol 30.95
    isooctanol 24.12
    dipropyl ether 29.22
    1,2-dichlorobenzene 58.45
    ethyl lactate 53.69
    propylene carbonate 139.1
    n-methylformamide 107.76
    2-pentanol 39.55
    n-pentane 1.75
    1-propoxy-2-propanol 100.09
    1-methoxy-2-propyl acetate 121.1
    2-(2-methoxypropoxy) propanol 109.91
    mesitylene 18.6
    ε-caprolactone 185.13
    p-cymene 16.38
    epichlorohydrin 262.93
    1,1,1-trichloroethane 90.03
    2-aminoethanol 55.56
    morpholine-4-carbaldehyde 254.09
    sulfolane 449.81
    2,2,4-trimethylpentane 3.18
    2-methyltetrahydrofuran 166.29
    n-hexyl acetate 83.39
    isooctane 2.09
    2-(2-butoxyethoxy)ethanol 153.02
    sec-butyl acetate 75.36
    tert-butyl acetate 122.05
    decalin 5.55
    glycerin 58.09
    diglyme 290.8
    acrylic acid 54.3
    isopropyl myristate 28.23
    n-butyric acid 115.16
    acetyl acetate 61.79
    di(2-ethylhexyl) phthalate 37.68
    ethyl propionate 71.5
    nitromethane 187.75
    1,2-diethoxyethane 116.22
    benzonitrile 68.5
    trioctyl phosphate 23.54
    1-bromopropane 56.45
    gamma-valerolactone 367.7
    n-decanol 15.27
    triethyl phosphate 42.54
    4-methyl-2-pentanol 31.71
    propionitrile 41.93
    vinylene carbonate 97.55
    1,1,2-trichlorotrifluoroethane 209.73
    DMS 68.05
    cumene 20.13
    2-octanol 18.03
    2-hexanone 107.78
    octyl acetate 35.32
    limonene 25.19
    1,2-dimethoxyethane 262.3
    ethyl orthosilicate 41.22
    tributyl phosphate 34.63
    diacetone alcohol 155.91
    N,N-dimethylaniline 52.68
    acrylonitrile 58.48
    aniline 41.95
    1,3-propanediol 83.33
    bromobenzene 45.9
    dibromomethane 89.49
    1,1,2,2-tetrachloroethane 211.51
    2-methyl-cyclohexyl acetate 73.45
    tetrabutyl urea 50.74
    diisobutyl methanol 20.48
    2-phenylethanol 53.73
    styrene 27.23
    dioctyl adipate 58.57
    dimethyl sulfate 88.16
    ethyl butyrate 70.39
    methyl lactate 54.15
    butyl lactate 72.27
    diethyl carbonate 44.42
    propanediol butyl ether 94.58
    triethyl orthoformate 53.23
    p-tert-butyltoluene 16.61
    methyl 4-tert-butylbenzoate 87.13
    morpholine 172.22
    tert-butylamine 60.33
    n-dodecanol 10.85
    dimethoxymethane 115.62
    ethylene carbonate 81.61
    cyrene 113.24
    2-ethoxyethyl acetate 113.92
    2-ethylhexyl acetate 75.72
    1,2,4-trichlorobenzene 74.36
    4-methylpyridine 111.11
    dibutyl ether 36.66
    2,6-dimethyl-4-heptanol 20.48
    DEF 143.13
    dimethyl isosorbide 194.5
    tetrachloroethylene 117.06
    eugenol 83.73
    triacetin 111.94
    span 80 82.82
    1,4-butanediol 38.51
    1,1-dichloroethane 90.22
    2-methyl-1-pentanol 67.77
    methyl formate 60.43
    2-methyl-1-butanol 59.13
    n-decane 2.01
    butyronitrile 56.2
    3,7-dimethyl-1-octanol 29.22
    1-chlorooctane 14.04
    1-chlorotetradecane 4.94
    n-nonane 1.74
    undecane 1.41
    tert-butylcyclohexane 5.16
    cyclooctane 1.38
    cyclopentanol 81.18
    tetrahydropyran 103.6
    tert-amyl methyl ether 69.81
    2,5,8-trioxanonane 195.59
    1-hexene 21.13
    2-isopropoxyethanol 122.66
    2,2,2-trifluoroethanol 37.88
    methyl butyrate 126.4

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction