Sodium glyoxylate

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  • Identifiers

    CAS number
    2706-75-4

    Molecular formula
    C2HNaO3

    SMILES
    C(=O)C(=O)[O-].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 60.79%
    Caramellic 55.57%
    Sour 44.33%
    Burnt 42.54%
    Sharp 35.61%
    Buttery 31.79%
    Sweet 30.71%
    Pungent 25.7%
    Fatty 22.51%
    Creamy 21.88%

     

    Flavor
    Odorless 49.07%
    Sour 37.04%
    Caramellic 29.44%
    Sweet 25.66%
    Very mild 24.67%
    Brown 23.84%
    Acidic 23.72%
    Nutty 23.52%
    Sharp 22.36%
    Caramel 21.85%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    3.28 (weak acid)

    Molecular weight
    96.02 g/mol

    Flash point

    • 52.62 ˚C est.

  • Synonyms

    • Sodium glyoxylate
    • Acetic acid, oxo-, sodium salt
    • GLYOXYLIC ACID, SODIUM SALT
    • 7X83124SCQ
    • CHEBI:91251
    • RefChem:183900
    • 220-298-8
    • 2706-75-4
    • sodium;oxaldehydate
    • sodium oxoacetate
    • Acetic acid, 2-oxo-, sodium salt (1:1)
    • sodium 2-oxoacetate
    • CCRIS 6298
    • EINECS 220-298-8
    • UNII-7X83124SCQ
    • sodium glyoxalate
    • 70205-95-7
    • Oxo-acetic acid sodium salt
    • SCHEMBL323948
    • CHEMBL3986754
    • DTXSID90949818
    • DB-255898
    • NS00083304
    • Q27163161
    • 2706-75-4

  • Applications

    Sodium glyoxylate (CAS 2706-75-4) is primarily used as a reactive organic synthesis intermediate, providing the glyoxylate moiety for aldol-type condensations to furnish α-hydroxy acids and related derivatives. It serves as a building block to access glyoxylate-containing compounds, including monomers and functionalized intermediates for polymers and resins in industrial manufacturing. In coatings, inks, and adhesives, it can act as a precursor to aldehyde-functional residues that enable crosslinking with amines or other nucleophiles, enhancing cure and network formation. As a reactive carbonyl source, it is commonly evaluated for further transformations and as a handle for tailoring functionality in specialty chemicals, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 104.07
    methanol 276.52
    isopropanol 59.31
    water 165.89
    ethyl acetate 69.3
    n-propanol 61.81
    acetone 230.23
    n-butanol 43.94
    acetonitrile 268.12
    DMF 875.51
    toluene 19.05
    isobutanol 38.79
    1,4-dioxane 152.55
    methyl acetate 144.23
    THF 115.03
    2-butanone 120.11
    n-pentanol 36.79
    sec-butanol 45.62
    n-hexane 5.65
    ethylene glycol 105.52
    NMP 511.65
    cyclohexane 9.94
    DMSO 841.19
    n-butyl acetate 25.47
    n-octanol 19.77
    chloroform 26.26
    n-propyl acetate 47.53
    acetic acid 107.6
    dichloromethane 66.16
    cyclohexanone 84.04
    propylene glycol 46.38
    isopropyl acetate 34.15
    DMAc 788.77
    2-ethoxyethanol 152.61
    isopentanol 34.82
    n-heptane 5.61
    ethyl formate 85.84
    1,2-dichloroethane 74.68
    n-hexanol 16.57
    2-methoxyethanol 249.2
    isobutyl acetate 18.92
    tetrachloromethane 6.29
    n-pentyl acetate 17.01
    transcutol 212.35
    n-heptanol 10.64
    ethylbenzene 14.72
    MIBK 33.96
    2-propoxyethanol 58.96
    tert-butanol 69.85
    MTBE 54.97
    2-butoxyethanol 32.61
    propionic acid 71.55
    o-xylene 28.22
    formic acid 188.22
    diethyl ether 66.76
    m-xylene 15.36
    p-xylene 18.2
    chlorobenzene 17.51
    dimethyl carbonate 81.48
    n-octane 2.85
    formamide 357.84
    cyclopentanone 96.34
    2-pentanone 62.34
    anisole 55.72
    cyclopentyl methyl ether 51.6
    gamma-butyrolactone 136.62
    1-methoxy-2-propanol 105.99
    pyridine 90.27
    3-pentanone 71.96
    furfural 173.19
    n-dodecane 3.25
    diethylene glycol 94.37
    diisopropyl ether 16.32
    tert-amyl alcohol 55.08
    acetylacetone 78.12
    n-hexadecane 3.4
    acetophenone 58.98
    methyl propionate 91.99
    isopentyl acetate 19.18
    trichloroethylene 63.83
    n-nonanol 17.88
    cyclohexanol 32.95
    benzyl alcohol 45.2
    2-ethylhexanol 12.9
    isooctanol 8.92
    dipropyl ether 27.31
    1,2-dichlorobenzene 20.44
    ethyl lactate 35.72
    propylene carbonate 56.24
    n-methylformamide 381.11
    2-pentanol 26.07
    n-pentane 7.78
    1-propoxy-2-propanol 38.12
    1-methoxy-2-propyl acetate 35.07
    2-(2-methoxypropoxy) propanol 70.63
    mesitylene 11.61
    ε-caprolactone 72.75
    p-cymene 10.54
    epichlorohydrin 123.67
    1,1,1-trichloroethane 24.18
    2-aminoethanol 101.18
    morpholine-4-carbaldehyde 398.01
    sulfolane 188.78
    2,2,4-trimethylpentane 3.91
    2-methyltetrahydrofuran 77.11
    n-hexyl acetate 27.02
    isooctane 2.08
    2-(2-butoxyethoxy)ethanol 72.59
    sec-butyl acetate 24.79
    tert-butyl acetate 30.08
    decalin 4.74
    glycerin 88.35
    diglyme 167.19
    acrylic acid 84.45
    isopropyl myristate 14.37
    n-butyric acid 43.5
    acetyl acetate 42.65
    di(2-ethylhexyl) phthalate 16.14
    ethyl propionate 49.38
    nitromethane 405.62
    1,2-diethoxyethane 62.5
    benzonitrile 47.74
    trioctyl phosphate 11.69
    1-bromopropane 32.56
    gamma-valerolactone 170.57
    n-decanol 15.03
    triethyl phosphate 23.07
    4-methyl-2-pentanol 15.37
    propionitrile 106.88
    vinylene carbonate 64.83
    1,1,2-trichlorotrifluoroethane 88.87
    DMS 43.84
    cumene 11.34
    2-octanol 9.43
    2-hexanone 47.13
    octyl acetate 18.76
    limonene 14.97
    1,2-dimethoxyethane 261.5
    ethyl orthosilicate 20.0
    tributyl phosphate 15.93
    diacetone alcohol 47.64
    N,N-dimethylaniline 59.91
    acrylonitrile 154.24
    aniline 39.11
    1,3-propanediol 87.34
    bromobenzene 13.1
    dibromomethane 37.42
    1,1,2,2-tetrachloroethane 49.35
    2-methyl-cyclohexyl acetate 20.06
    tetrabutyl urea 34.72
    diisobutyl methanol 10.88
    2-phenylethanol 22.58
    styrene 18.95
    dioctyl adipate 26.58
    dimethyl sulfate 146.89
    ethyl butyrate 30.74
    methyl lactate 64.68
    butyl lactate 21.24
    diethyl carbonate 27.48
    propanediol butyl ether 40.82
    triethyl orthoformate 26.75
    p-tert-butyltoluene 9.39
    methyl 4-tert-butylbenzoate 38.17
    morpholine 173.14
    tert-butylamine 38.46
    n-dodecanol 12.73
    dimethoxymethane 230.11
    ethylene carbonate 52.45
    cyrene 69.69
    2-ethoxyethyl acetate 33.14
    2-ethylhexyl acetate 15.78
    1,2,4-trichlorobenzene 25.67
    4-methylpyridine 87.55
    dibutyl ether 25.25
    2,6-dimethyl-4-heptanol 10.88
    DEF 177.31
    dimethyl isosorbide 79.17
    tetrachloroethylene 35.26
    eugenol 42.12
    triacetin 47.66
    span 80 34.11
    1,4-butanediol 53.99
    1,1-dichloroethane 38.37
    2-methyl-1-pentanol 30.48
    methyl formate 273.72
    2-methyl-1-butanol 35.6
    n-decane 4.47
    butyronitrile 63.35
    3,7-dimethyl-1-octanol 18.34
    1-chlorooctane 10.73
    1-chlorotetradecane 6.26
    n-nonane 4.31
    undecane 3.75
    tert-butylcyclohexane 3.4
    cyclooctane 4.46
    cyclopentanol 37.91
    tetrahydropyran 67.93
    tert-amyl methyl ether 49.42
    2,5,8-trioxanonane 129.99
    1-hexene 13.79
    2-isopropoxyethanol 74.65
    2,2,2-trifluoroethanol 84.99
    methyl butyrate 64.54

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction