Sodium Glycerophosphate

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  • Identifiers

    CAS number
    55073-41-1

    Molecular formula
    C3H7Na2O6P

    SMILES
    C(C(COP(=O)([O-])[O-])O)O.[Na+].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 76.37%
    Sweet 30.08%
    Alcoholic 19.27%
    Clean 18.6%
    Savory 16.54%
    Buttery 15.92%
    Milky 15.29%
    Bitter 13.92%
    Cooling 13.86%
    Oily 13.48%

     

    Flavor
    Odorless 77.68%
    Very mild 29.19%
    Mild 26.76%
    Bland 26.27%
    Sweet-like 25.8%
    Sour 25.36%
    Yeast 21.64%
    Acidic 20.95%
    Faint 20.82%
    Very slight 20.62%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.21 (weak acid)

    Molecular weight
    216.04 g/mol

    Flash point

    • 150.05 ˚C est.

    Solubility expt.

    • Soluble

  • Synonyms

    • SODIUM GLYCEROPHOSPHATE
    • Sodium glycerophosphate hydrate
    • RefChem:886696
    • 241-577-0
    • 1,2,3-Propanetriol, Mono(dihydrogen Phosphate), Disodium Salt, Hydrate
    • 55073-41-1
    • RCS9EQ01V4
    • 1555-56-2
    • alpha-Glycerophosphoric Acid Disodium Salt
    • Disodium alpha-glycerophosphate
    • Sodium 1-glycerophosphate
    • 1334-74-3
    • disodium;2,3-dihydroxypropyl phosphate
    • 1300-25-0
    • Sodium 2,3-dihydroxypropyl phosphate
    • disodium 2,3-dihydroxypropyl phosphate
    • Disodium glycerol phosphate
    • Sodium glycerophosphate anhydrous
    • 1,2,3-Propanetriol, 1-(dihydrogen phosphate), disodium salt
    • 1,2,3-Propanetriol, 1-(dihydrogen phosphate), sodium salt (1:2)
    • G43E72677U
    • 1,2,3-Propanetriol, mono(dihydrogen phosphate), disodium salt
    • DISODIUM 3-(PHOSPHONATOOXY)PROPANE-1,2-DIOL
    • alpha-glycerophosphate disodium salt
    • Disodium 1-glycerophosphate
    • Sodium-|A-glycerophosphate
    • UNII-YP1H63LJ2K
    • rac-Glycerol 1-phosphate Sodium Salt Hydrate
    • UNII-G43E72677U
    • Disodium DL-alpha-glycerophosphate
    • EINECS 215-613-0
    • EINECS 216-304-3
    • Rac-glycero-1-phosphate, sodium salt
    • DL-a-glycerophosphoric acid disodium salt
    • AI3-52663
    • Disodium a-glycerophosphate
    • YP1H63LJ2K
    • SCHEMBL124155
    • -Glycerophosphate disodium salt
    • orb1983530
    • Glycerophosphate disodium hydrate
    • GEKBIENFFVFKRG-UHFFFAOYSA-L
    • DTXSID801014666
    • Glycerol, mono(dihydrogen phosphate), disodium salt. hydrate
    • EBC-26224
    • MFCD00035539
    • MFCD00150341
    • SODIUM RAC-1-GLYCEROPHOSPHATE
    • AKOS015914412
    • AKOS024319279
    • DB09561
    • SY105606
    • disodium 3-(phosphonooxy)propane-1,2-diol
    • DISODIUM DL-.ALPHA.-GLYCEROPHOSPHATE
    • G0096
    • NS00079769
    • DISODIUM DL-.ALPHA.-GLYCERIN PHOSPHATE
    • D90711
    • SBI-0653869.0001
    • EN300-7863244
    • Q27278714
    • ALPHA-GLYCEROPHOSPHORIC ACID DISODIUM SALT HYDRATE
    • 1,2,3-Propanetriol, mono(dihydrogen phosphate), sodium salt (1:2)
    • 1555-56-2

  • Applications

    Sodium glycerophosphate is used as a pH buffering and stabilizing agent in cosmetics and personal care formulations, and acts as a chelating agent to mitigate metal ion effects in cleaning products and other industrial formulations. It can provide a phosphate source for biochemical and industrial production processes, and may function as a processing aid or stabilizer in polymer, coating, and ink formulations. Additionally, it is used as a reagent or intermediate in research and development applications in biochemistry and analytical contexts.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 110.79
    methanol 294.39
    isopropanol 60.25
    water 413.71
    ethyl acetate 10.09
    n-propanol 47.5
    acetone 70.56
    n-butanol 35.37
    acetonitrile 22.38
    DMF 382.74
    toluene 4.81
    isobutanol 19.99
    1,4-dioxane 43.66
    methyl acetate 15.55
    THF 65.71
    2-butanone 20.12
    n-pentanol 16.88
    sec-butanol 27.81
    n-hexane 0.94
    ethylene glycol 262.13
    NMP 224.22
    cyclohexane 4.45
    DMSO 518.59
    n-butyl acetate 8.25
    n-octanol 11.04
    chloroform 2.06
    n-propyl acetate 5.78
    acetic acid 69.21
    dichloromethane 5.17
    cyclohexanone 21.75
    propylene glycol 135.03
    isopropyl acetate 7.12
    DMAc 197.59
    2-ethoxyethanol 116.77
    isopentanol 20.68
    n-heptane 3.7
    ethyl formate 22.49
    1,2-dichloroethane 9.11
    n-hexanol 20.39
    2-methoxyethanol 315.64
    isobutyl acetate 1.96
    tetrachloromethane 1.14
    n-pentyl acetate 7.31
    transcutol 95.15
    n-heptanol 15.06
    ethylbenzene 2.4
    MIBK 9.25
    2-propoxyethanol 79.77
    tert-butanol 56.38
    MTBE 12.56
    2-butoxyethanol 50.13
    propionic acid 26.89
    o-xylene 6.96
    formic acid 307.71
    diethyl ether 16.15
    m-xylene 4.87
    p-xylene 2.62
    chlorobenzene 2.02
    dimethyl carbonate 21.3
    n-octane 1.39
    formamide 400.67
    cyclopentanone 38.25
    2-pentanone 18.22
    anisole 7.6
    cyclopentyl methyl ether 19.68
    gamma-butyrolactone 45.17
    1-methoxy-2-propanol 161.42
    pyridine 19.0
    3-pentanone 10.93
    furfural 64.92
    n-dodecane 0.91
    diethylene glycol 178.79
    diisopropyl ether 4.57
    tert-amyl alcohol 31.25
    acetylacetone 28.67
    n-hexadecane 0.97
    acetophenone 11.18
    methyl propionate 16.63
    isopentyl acetate 5.73
    trichloroethylene 5.94
    n-nonanol 10.24
    cyclohexanol 21.8
    benzyl alcohol 16.63
    2-ethylhexanol 8.15
    isooctanol 8.78
    dipropyl ether 10.24
    1,2-dichlorobenzene 2.45
    ethyl lactate 15.9
    propylene carbonate 15.53
    n-methylformamide 181.5
    2-pentanol 18.76
    n-pentane 2.95
    1-propoxy-2-propanol 45.92
    1-methoxy-2-propyl acetate 17.99
    2-(2-methoxypropoxy) propanol 38.53
    mesitylene 4.39
    ε-caprolactone 19.98
    p-cymene 4.18
    epichlorohydrin 36.0
    1,1,1-trichloroethane 1.77
    2-aminoethanol 197.34
    morpholine-4-carbaldehyde 169.77
    sulfolane 100.05
    2,2,4-trimethylpentane 0.88
    2-methyltetrahydrofuran 25.23
    n-hexyl acetate 8.26
    isooctane 0.66
    2-(2-butoxyethoxy)ethanol 58.08
    sec-butyl acetate 3.05
    tert-butyl acetate 9.42
    decalin 0.88
    glycerin 295.25
    diglyme 92.42
    acrylic acid 42.81
    isopropyl myristate 3.95
    n-butyric acid 22.5
    acetyl acetate 7.04
    di(2-ethylhexyl) phthalate 6.37
    ethyl propionate 5.48
    nitromethane 101.37
    1,2-diethoxyethane 14.69
    benzonitrile 7.49
    trioctyl phosphate 6.33
    1-bromopropane 3.19
    gamma-valerolactone 75.05
    n-decanol 8.05
    triethyl phosphate 6.09
    4-methyl-2-pentanol 8.07
    propionitrile 10.78
    vinylene carbonate 14.17
    1,1,2-trichlorotrifluoroethane 55.44
    DMS 7.45
    cumene 2.03
    2-octanol 7.38
    2-hexanone 6.74
    octyl acetate 6.37
    limonene 5.95
    1,2-dimethoxyethane 80.01
    ethyl orthosilicate 5.42
    tributyl phosphate 5.05
    diacetone alcohol 40.33
    N,N-dimethylaniline 11.34
    acrylonitrile 19.61
    aniline 12.95
    1,3-propanediol 172.17
    bromobenzene 1.45
    dibromomethane 3.28
    1,1,2,2-tetrachloroethane 8.11
    2-methyl-cyclohexyl acetate 5.91
    tetrabutyl urea 13.07
    diisobutyl methanol 6.1
    2-phenylethanol 16.3
    styrene 2.38
    dioctyl adipate 6.81
    dimethyl sulfate 47.12
    ethyl butyrate 7.21
    methyl lactate 53.41
    butyl lactate 13.61
    diethyl carbonate 5.14
    propanediol butyl ether 49.39
    triethyl orthoformate 7.17
    p-tert-butyltoluene 4.57
    methyl 4-tert-butylbenzoate 19.59
    morpholine 65.07
    tert-butylamine 21.61
    n-dodecanol 6.17
    dimethoxymethane 115.22
    ethylene carbonate 11.55
    cyrene 48.29
    2-ethoxyethyl acetate 12.66
    2-ethylhexyl acetate 4.03
    1,2,4-trichlorobenzene 3.31
    4-methylpyridine 14.93
    dibutyl ether 4.69
    2,6-dimethyl-4-heptanol 6.1
    DEF 45.99
    dimethyl isosorbide 43.75
    tetrachloroethylene 7.59
    eugenol 25.39
    triacetin 11.9
    span 80 29.63
    1,4-butanediol 73.2
    1,1-dichloroethane 2.96
    2-methyl-1-pentanol 9.53
    methyl formate 105.59
    2-methyl-1-butanol 16.96
    n-decane 1.33
    butyronitrile 11.21
    3,7-dimethyl-1-octanol 7.01
    1-chlorooctane 2.55
    1-chlorotetradecane 1.36
    n-nonane 1.36
    undecane 1.08
    tert-butylcyclohexane 0.57
    cyclooctane 2.55
    cyclopentanol 31.69
    tetrahydropyran 17.76
    tert-amyl methyl ether 11.39
    2,5,8-trioxanonane 76.59
    1-hexene 1.64
    2-isopropoxyethanol 44.86
    2,2,2-trifluoroethanol 48.86
    methyl butyrate 8.66

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction