SODIUM ETHYL p-HYDROXYBENZOATE

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  • Identifiers

    CAS number
    35285-68-8

    Molecular formula
    C9H10NaO3

    SMILES
    CCOC(=O)C1=CC=C(C=C1)O.[Na]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Phenolic 65.49%
    Sweet 49.06%
    Vanilla 40.43%
    Floral 40.39%
    Aromatic 39.14%
    Spicy 36.78%
    Medicinal 36.48%
    Balsamic 35.34%
    Animal 35.27%
    Smoky 31.94%

     

    Flavor
    Sweet 63.15%
    Balsam 54.96%
    Floral 50.43%
    Wintergreen 45.99%
    Bitter 43.32%
    Powdery 40.25%
    Balsamic 34.74%
    Vanilla 34.57%
    Fruity 33.12%
    Minty 32.03%

     

    Odor impact est.
    Medium

  • Properties

    pKa est.
    8.08 (weak base)

    Molecular weight
    189.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    309°C

    Melting point expt.

    • ofp-hydroxybenzoic acid derived from the sample is 213 °C to 217 °C

    Flash point

    • 129.11 ˚C est.

  • Synonyms

    • Sodium ethyl p-hydroxybenzoate
    • RefChem:1098791
    • 35285-68-8
    • Benzoic acid, 4-hydroxy-, ethyl ester, sodium salt
    • p-Hydroxybenzoic acid ethyl ester sodium salt
    • Sodium Ethyl Paraben
    • SCHEMBL29358972
    • AKOS025311006
    • AKOS028109570
    • 285S688
    • p-Hydroxybenzoic acid ethyl ester sodium salt;Sodium 2-ethyl-4-hydroxybenzoate
    • 35285-68-8

  • Applications

    Sodium Ethyl p-HYDROXYBENZOATE (CAS 35285-68-8) is used primarily as a preservative in cosmetic and personal care formulations to control microbial growth; it is also encountered as a preservative in pharmaceutical products and in some household cleaning formulations. In addition, it may be evaluated for use as an antimicrobial additive or stabilizer in certain industrial formulations, and in some coatings and inks where microbial contamination during storage is a concern. The use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 534.17
    methanol 621.41
    isopropanol 493.57
    water 0.7
    ethyl acetate 431.01
    n-propanol 399.56
    acetone 1140.03
    n-butanol 286.5
    acetonitrile 587.2
    DMF 1883.78
    toluene 59.15
    isobutanol 235.32
    1,4-dioxane 665.13
    methyl acetate 533.32
    THF 918.49
    2-butanone 611.55
    n-pentanol 234.96
    sec-butanol 344.27
    n-hexane 8.76
    ethylene glycol 129.35
    NMP 1018.43
    cyclohexane 5.78
    DMSO 2479.2
    n-butyl acetate 309.27
    n-octanol 127.37
    chloroform 370.95
    n-propyl acetate 325.62
    acetic acid 672.57
    dichloromethane 510.16
    cyclohexanone 548.28
    propylene glycol 170.69
    isopropyl acetate 226.16
    DMAc 873.98
    2-ethoxyethanol 449.22
    isopentanol 228.18
    n-heptane 6.19
    ethyl formate 287.09
    1,2-dichloroethane 431.34
    n-hexanol 168.8
    2-methoxyethanol 669.97
    isobutyl acetate 153.24
    tetrachloromethane 21.96
    n-pentyl acetate 156.31
    transcutol 1403.15
    n-heptanol 86.85
    ethylbenzene 56.45
    MIBK 229.2
    2-propoxyethanol 322.41
    tert-butanol 602.61
    MTBE 339.0
    2-butoxyethanol 192.02
    propionic acid 410.86
    o-xylene 59.63
    formic acid 281.05
    diethyl ether 312.29
    m-xylene 62.77
    p-xylene 80.08
    chlorobenzene 142.6
    dimethyl carbonate 208.83
    n-octane 4.45
    formamide 747.52
    cyclopentanone 875.18
    2-pentanone 450.16
    anisole 236.57
    cyclopentyl methyl ether 282.33
    gamma-butyrolactone 1059.07
    1-methoxy-2-propanol 515.59
    pyridine 344.98
    3-pentanone 275.34
    furfural 641.21
    n-dodecane 6.54
    diethylene glycol 303.03
    diisopropyl ether 72.37
    tert-amyl alcohol 416.86
    acetylacetone 533.42
    n-hexadecane 7.61
    acetophenone 245.14
    methyl propionate 373.88
    isopentyl acetate 231.16
    trichloroethylene 699.04
    n-nonanol 110.09
    cyclohexanol 181.79
    benzyl alcohol 192.24
    2-ethylhexanol 95.75
    isooctanol 75.78
    dipropyl ether 111.7
    1,2-dichlorobenzene 137.16
    ethyl lactate 153.62
    propylene carbonate 399.72
    n-methylformamide 808.78
    2-pentanol 208.02
    n-pentane 6.31
    1-propoxy-2-propanol 235.83
    1-methoxy-2-propyl acetate 249.85
    2-(2-methoxypropoxy) propanol 234.12
    mesitylene 43.99
    ε-caprolactone 459.57
    p-cymene 40.7
    epichlorohydrin 929.47
    1,1,1-trichloroethane 190.88
    2-aminoethanol 233.5
    morpholine-4-carbaldehyde 766.84
    sulfolane 1286.61
    2,2,4-trimethylpentane 9.15
    2-methyltetrahydrofuran 542.31
    n-hexyl acetate 253.38
    isooctane 7.11
    2-(2-butoxyethoxy)ethanol 351.22
    sec-butyl acetate 174.7
    tert-butyl acetate 260.23
    decalin 10.75
    glycerin 250.36
    diglyme 608.55
    acrylic acid 393.36
    isopropyl myristate 88.54
    n-butyric acid 379.03
    acetyl acetate 228.48
    di(2-ethylhexyl) phthalate 77.76
    ethyl propionate 234.24
    nitromethane 1593.48
    1,2-diethoxyethane 297.35
    benzonitrile 234.45
    trioctyl phosphate 64.94
    1-bromopropane 157.03
    gamma-valerolactone 845.53
    n-decanol 83.82
    triethyl phosphate 88.66
    4-methyl-2-pentanol 109.2
    propionitrile 311.46
    vinylene carbonate 348.18
    1,1,2-trichlorotrifluoroethane 450.15
    DMS 231.12
    cumene 46.55
    2-octanol 77.7
    2-hexanone 324.6
    octyl acetate 120.04
    limonene 59.3
    1,2-dimethoxyethane 656.02
    ethyl orthosilicate 77.04
    tributyl phosphate 87.46
    diacetone alcohol 353.57
    N,N-dimethylaniline 144.75
    acrylonitrile 479.54
    aniline 161.88
    1,3-propanediol 330.77
    bromobenzene 115.18
    dibromomethane 265.3
    1,1,2,2-tetrachloroethane 493.95
    2-methyl-cyclohexyl acetate 131.57
    tetrabutyl urea 117.99
    diisobutyl methanol 64.36
    2-phenylethanol 151.81
    styrene 80.97
    dioctyl adipate 132.7
    dimethyl sulfate 402.41
    ethyl butyrate 181.42
    methyl lactate 212.08
    butyl lactate 140.97
    diethyl carbonate 132.0
    propanediol butyl ether 254.26
    triethyl orthoformate 117.56
    p-tert-butyltoluene 40.43
    methyl 4-tert-butylbenzoate 178.54
    morpholine 746.19
    tert-butylamine 253.36
    n-dodecanol 60.04
    dimethoxymethane 649.45
    ethylene carbonate 279.19
    cyrene 217.52
    2-ethoxyethyl acetate 245.69
    2-ethylhexyl acetate 162.59
    1,2,4-trichlorobenzene 190.89
    4-methylpyridine 363.99
    dibutyl ether 144.55
    2,6-dimethyl-4-heptanol 64.36
    DEF 478.06
    dimethyl isosorbide 317.0
    tetrachloroethylene 247.24
    eugenol 184.61
    triacetin 246.01
    span 80 175.6
    1,4-butanediol 147.55
    1,1-dichloroethane 330.42
    2-methyl-1-pentanol 188.72
    methyl formate 588.29
    2-methyl-1-butanol 205.73
    n-decane 9.79
    butyronitrile 276.94
    3,7-dimethyl-1-octanol 112.15
    1-chlorooctane 61.8
    1-chlorotetradecane 26.0
    n-nonane 8.54
    undecane 7.99
    tert-butylcyclohexane 12.08
    cyclooctane 2.85
    cyclopentanol 264.79
    tetrahydropyran 426.74
    tert-amyl methyl ether 221.78
    2,5,8-trioxanonane 379.92
    1-hexene 64.28
    2-isopropoxyethanol 286.6
    2,2,2-trifluoroethanol 215.11
    methyl butyrate 333.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction