Sodium ethanesulphonate

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  • Identifiers

    CAS number
    5324-47-0

    Molecular formula
    C2H5NaO3S

    SMILES
    CCS(=O)(=O)[O-].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 80.99%
    Sulfurous 23.85%
    Roasted 21.26%
    Savory 20.44%
    Cooked 20.11%
    Pungent 18.41%
    Meaty 15.1%
    Burnt 14.46%
    Onion 13.53%
    Sharp 12.94%

     

    Flavor
    Bitter 52.63%
    Odorless 29.85%
    Bland 24.36%
    Sulfur 24.01%
    Mustard 20.93%
    Taco 20.55%
    Formyl 20.51%
    Nitrile 20.41%
    Roasted peanuts 20.11%
    Mousy 19.98%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    6.63 (neutral)

    Molecular weight
    132.12 g/mol

    Flash point

    • 83.52 ˚C est.

  • Synonyms

    • 5324-47-0
    • Sodium ethanesulphonate
    • EINECS 226-194-9
    • DTXSID20201335
    • NSC 2695
    • RefChem:183879
    • DTXCID20123826
    • 226-194-9
    • Sodium Ethanesulfonate
    • Ethanesulfonic Acid Sodium Salt
    • sodium;ethanesulfonate
    • MFCD00066498
    • ETHANESULFONIC ACID, SODIUM SALT
    • ethane sulfonic acid sodium salt
    • Sodium ethylsulfonate
    • sodium ethane sulfonate
    • C2H5NaO3S
    • SCHEMBL124278
    • Ethylsulfonic Acid Sodium Salt
    • SCHEMBL1489867
    • KQFAFFYKLIBKDE-UHFFFAOYSA-M
    • AKOS027327434
    • AS-57759
    • SY100985
    • CS-0206836
    • E0256
    • NS00081491
    • D78206
    • Ethanesulfonic acid sodium salt, 98%, may cont. ca 2% water
    • 5324-47-0

  • Applications

    Sodium ethanesulphonate (CAS 5324-47-0) is a small, highly water-soluble sulfonate salt used primarily as a chemical intermediate and as a counterion to form water-soluble salts of amine-containing compounds. In pharmaceutical and personal care formulation development, it is often employed to prepare hydrophilic ethanesulphonate salts that improve solubility and handling. In organic synthesis, it serves as a source of the ethanesulphonate moiety for creating sulfonated derivatives or as a stabilizing salt in certain reaction media. In polymer and coatings manufacturing, it can act as an ionic-strength modifier or processing aid, helping solubility of additives and compatibility in aqueous systems. It may also find niche use as an electrolyte or supporting salt in specialty electrochemical or electronics-related formulations where a simple, highly soluble sulfonate salt is desired.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 159.1
    methanol 352.48
    isopropanol 107.83
    water 139.75
    ethyl acetate 150.11
    n-propanol 91.03
    acetone 523.81
    n-butanol 80.03
    acetonitrile 523.63
    DMF 1031.29
    toluene 53.89
    isobutanol 65.55
    1,4-dioxane 303.74
    methyl acetate 285.43
    THF 170.16
    2-butanone 272.64
    n-pentanol 67.91
    sec-butanol 96.98
    n-hexane 11.37
    ethylene glycol 128.52
    NMP 706.98
    cyclohexane 17.64
    DMSO 900.6
    n-butyl acetate 73.04
    n-octanol 62.03
    chloroform 138.1
    n-propyl acetate 107.68
    acetic acid 320.6
    dichloromethane 244.74
    cyclohexanone 283.45
    propylene glycol 82.25
    isopropyl acetate 84.43
    DMAc 861.78
    2-ethoxyethanol 217.77
    isopentanol 73.39
    n-heptane 9.56
    ethyl formate 231.08
    1,2-dichloroethane 226.7
    n-hexanol 49.55
    2-methoxyethanol 378.8
    isobutyl acetate 44.41
    tetrachloromethane 23.46
    n-pentyl acetate 69.14
    transcutol 430.93
    n-heptanol 37.14
    ethylbenzene 47.78
    MIBK 92.47
    2-propoxyethanol 115.27
    tert-butanol 134.16
    MTBE 104.96
    2-butoxyethanol 82.02
    propionic acid 159.13
    o-xylene 71.85
    formic acid 374.9
    diethyl ether 110.97
    m-xylene 44.13
    p-xylene 68.25
    chlorobenzene 93.44
    dimethyl carbonate 131.36
    n-octane 6.88
    formamide 706.7
    cyclopentanone 307.71
    2-pentanone 172.45
    anisole 159.01
    cyclopentyl methyl ether 86.53
    gamma-butyrolactone 368.3
    1-methoxy-2-propanol 194.23
    pyridine 232.39
    3-pentanone 161.19
    furfural 565.99
    n-dodecane 7.41
    diethylene glycol 156.57
    diisopropyl ether 30.94
    tert-amyl alcohol 123.9
    acetylacetone 315.87
    n-hexadecane 8.19
    acetophenone 218.52
    methyl propionate 158.48
    isopentyl acetate 57.95
    trichloroethylene 328.39
    n-nonanol 54.46
    cyclohexanol 82.38
    benzyl alcohol 119.98
    2-ethylhexanol 34.79
    isooctanol 29.87
    dipropyl ether 39.51
    1,2-dichlorobenzene 125.58
    ethyl lactate 75.47
    propylene carbonate 187.61
    n-methylformamide 508.83
    2-pentanol 60.49
    n-pentane 13.39
    1-propoxy-2-propanol 72.09
    1-methoxy-2-propyl acetate 83.61
    2-(2-methoxypropoxy) propanol 135.46
    mesitylene 35.38
    ε-caprolactone 226.08
    p-cymene 30.19
    epichlorohydrin 309.05
    1,1,1-trichloroethane 92.08
    2-aminoethanol 139.27
    morpholine-4-carbaldehyde 689.43
    sulfolane 470.08
    2,2,4-trimethylpentane 8.46
    2-methyltetrahydrofuran 137.95
    n-hexyl acetate 101.29
    isooctane 4.79
    2-(2-butoxyethoxy)ethanol 164.71
    sec-butyl acetate 59.19
    tert-butyl acetate 85.9
    decalin 10.93
    glycerin 152.88
    diglyme 312.48
    acrylic acid 211.53
    isopropyl myristate 47.41
    n-butyric acid 121.42
    acetyl acetate 136.0
    di(2-ethylhexyl) phthalate 55.01
    ethyl propionate 99.91
    nitromethane 1001.2
    1,2-diethoxyethane 138.48
    benzonitrile 192.99
    trioctyl phosphate 38.96
    1-bromopropane 72.62
    gamma-valerolactone 494.74
    n-decanol 43.9
    triethyl phosphate 46.07
    4-methyl-2-pentanol 36.59
    propionitrile 172.69
    vinylene carbonate 242.65
    1,1,2-trichlorotrifluoroethane 255.81
    DMS 120.92
    cumene 36.54
    2-octanol 36.81
    2-hexanone 122.27
    octyl acetate 63.47
    limonene 42.57
    1,2-dimethoxyethane 425.47
    ethyl orthosilicate 39.41
    tributyl phosphate 51.08
    diacetone alcohol 134.46
    N,N-dimethylaniline 138.33
    acrylonitrile 334.02
    aniline 105.02
    1,3-propanediol 159.72
    bromobenzene 76.95
    dibromomethane 128.29
    1,1,2,2-tetrachloroethane 232.05
    2-methyl-cyclohexyl acetate 60.95
    tetrabutyl urea 91.4
    diisobutyl methanol 25.07
    2-phenylethanol 79.47
    styrene 65.6
    dioctyl adipate 77.69
    dimethyl sulfate 266.54
    ethyl butyrate 72.07
    methyl lactate 125.05
    butyl lactate 63.05
    diethyl carbonate 59.53
    propanediol butyl ether 112.99
    triethyl orthoformate 47.06
    p-tert-butyltoluene 27.67
    methyl 4-tert-butylbenzoate 117.18
    morpholine 258.12
    tert-butylamine 81.66
    n-dodecanol 35.77
    dimethoxymethane 308.2
    ethylene carbonate 168.47
    cyrene 150.83
    2-ethoxyethyl acetate 117.86
    2-ethylhexyl acetate 48.62
    1,2,4-trichlorobenzene 137.69
    4-methylpyridine 259.37
    dibutyl ether 61.22
    2,6-dimethyl-4-heptanol 25.07
    DEF 311.13
    dimethyl isosorbide 174.7
    tetrachloroethylene 163.91
    eugenol 126.8
    triacetin 141.13
    span 80 94.63
    1,4-butanediol 81.18
    1,1-dichloroethane 124.4
    2-methyl-1-pentanol 65.59
    methyl formate 469.8
    2-methyl-1-butanol 71.38
    n-decane 10.87
    butyronitrile 136.51
    3,7-dimethyl-1-octanol 55.16
    1-chlorooctane 34.74
    1-chlorotetradecane 17.98
    n-nonane 10.41
    undecane 8.79
    tert-butylcyclohexane 8.4
    cyclooctane 8.03
    cyclopentanol 82.74
    tetrahydropyran 117.73
    tert-amyl methyl ether 94.33
    2,5,8-trioxanonane 252.92
    1-hexene 31.7
    2-isopropoxyethanol 120.56
    2,2,2-trifluoroethanol 202.59
    methyl butyrate 150.91

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction