Sodium Ascorbyl/Cholesteryl Phosphate

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  • Identifiers

    CAS number
    185018-43-3

    Molecular formula
    C33H52NaO9P

    SMILES
    C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)OP(=O)([O-])OC5=C([C@H](OC5=O)[C@H](CO)O)O)C)C.[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Woody 45.01%
    Odorless 43.71%
    Balsamic 33.57%
    Amber 28.67%
    Sandalwood 25.96%
    Dry 25.5%
    Herbal 25.12%
    Fresh 24.15%
    Spicy 23.43%
    Clean 22.36%

     

    Flavor
    Odorless 34.15%
    Bitter 34.12%
    Bland 29.74%
    Mild 25.11%
    Cedarleaf 21.13%
    Sweet-like 20.34%
    Sandalwood 20.27%
    Slightly waxy 19.92%
    Ripe apricot 19.52%
    Parsley 19.51%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    4.72 (weak acid)

    Molecular weight
    646.7 g/mol

    Flash point

    • 292.35 ˚C est.

  • Synonyms

    • Sodium ascorbyl/cholesteryl phosphate
    • AVC-10
    • 185018-43-3
    • UNII-DE09065B2O
    • DE09065B2O
    • L-Ascorbic acid, 2-((3beta)-cholest-5-en-3-yl hydrogen phosphate), monosodium salt
    • L-ASCORBIC ACID, 2-((3.BETA.)-CHOLEST-5-EN-3-YL HYDROGEN PHOSPHATE), MONOSODIUM SALT
    • L-Ascorbic acid, 2-[(3.beta.)-cholest-5-en-3-yl hydrogen phosphate], monosodium salt
    • L-ASCORBIC ACID, 2-[(3beta)-CHOLEST-5-EN-3-YL HYDROGEN PHOSPHATE], MONOSODIUM SALT
    • RefChem:183787
    • SODIUM ASCORBYL/CHOLESTERYL PHOSPHATE [INCI]
    • 606-043-7
    • sodium;[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-yl] [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] phosphate
    • SCHEMBL30967429
    • DTXSID001021869
    • Q27276345
    • 185018-43-3

  • Applications

    Sodium Ascorbyl/Cholesteryl Phosphate (CAS 185018-43-3) is a multifunctional ingredient commonly evaluated for use in cosmetic and personal-care formulations, where it can act as an antioxidant and stabilizer for vitamin C–rich systems and may provide emollient or conditioning benefits from the cholesteryl phosphate moiety. It may also serve as a surfactant or co-surfactant in cleansing and cleaning products, and can function as a stabilizer or dispersing aid in coatings, inks, and pigment formulations. In polymer and plastic formulations, it may act as a processing aid or compatibilizer, and it may be considered as an intermediate in pharmaceutical formulation development, subject to formulation limits and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.04
    methanol 14.42
    isopropanol 2.78
    water 0.11
    ethyl acetate 4.41
    n-propanol 4.44
    acetone 10.4
    n-butanol 2.48
    acetonitrile 2.87
    DMF 31.84
    toluene 1.26
    isobutanol 1.93
    1,4-dioxane 9.49
    methyl acetate 5.68
    THF 24.44
    2-butanone 7.09
    n-pentanol 2.19
    sec-butanol 1.8
    n-hexane 0.06
    ethylene glycol 2.86
    NMP 39.13
    cyclohexane 0.1
    DMSO 26.89
    n-butyl acetate 3.04
    n-octanol 1.64
    chloroform 13.89
    n-propyl acetate 3.26
    acetic acid 24.88
    dichloromethane 10.89
    cyclohexanone 9.97
    propylene glycol 4.81
    isopropyl acetate 3.26
    DMAc 39.58
    2-ethoxyethanol 13.08
    isopentanol 1.65
    n-heptane 0.07
    ethyl formate 5.14
    1,2-dichloroethane 5.09
    n-hexanol 2.14
    2-methoxyethanol 22.83
    isobutyl acetate 1.99
    tetrachloromethane 1.87
    n-pentyl acetate 4.79
    transcutol 16.36
    n-heptanol 2.51
    ethylbenzene 0.54
    MIBK 3.03
    2-propoxyethanol 15.24
    tert-butanol 2.3
    MTBE 1.69
    2-butoxyethanol 11.33
    propionic acid 7.63
    o-xylene 0.91
    formic acid 15.04
    diethyl ether 1.99
    m-xylene 1.01
    p-xylene 0.81
    chlorobenzene 2.22
    dimethyl carbonate 7.15
    n-octane 0.05
    formamide 16.19
    cyclopentanone 18.92
    2-pentanone 4.85
    anisole 2.7
    cyclopentyl methyl ether 4.05
    gamma-butyrolactone 21.76
    1-methoxy-2-propanol 14.21
    pyridine 8.69
    3-pentanone 3.63
    furfural 17.0
    n-dodecane 0.04
    diethylene glycol 12.35
    diisopropyl ether 0.52
    tert-amyl alcohol 1.78
    acetylacetone 10.49
    n-hexadecane 0.04
    acetophenone 4.65
    methyl propionate 5.66
    isopentyl acetate 2.76
    trichloroethylene 15.25
    n-nonanol 1.78
    cyclohexanol 1.67
    benzyl alcohol 4.14
    2-ethylhexanol 0.99
    isooctanol 1.76
    dipropyl ether 1.32
    1,2-dichlorobenzene 2.39
    ethyl lactate 4.26
    propylene carbonate 8.88
    n-methylformamide 16.72
    2-pentanol 1.1
    n-pentane 0.07
    1-propoxy-2-propanol 7.65
    1-methoxy-2-propyl acetate 7.13
    2-(2-methoxypropoxy) propanol 7.43
    mesitylene 0.59
    ε-caprolactone 9.52
    p-cymene 0.6
    epichlorohydrin 18.7
    1,1,1-trichloroethane 4.2
    2-aminoethanol 7.36
    morpholine-4-carbaldehyde 30.38
    sulfolane 31.74
    2,2,4-trimethylpentane 0.05
    2-methyltetrahydrofuran 5.83
    n-hexyl acetate 4.18
    isooctane 0.04
    2-(2-butoxyethoxy)ethanol 10.3
    sec-butyl acetate 1.89
    tert-butyl acetate 3.64
    decalin 0.07
    glycerin 10.48
    diglyme 16.89
    acrylic acid 11.18
    isopropyl myristate 1.06
    n-butyric acid 7.92
    acetyl acetate 5.44
    di(2-ethylhexyl) phthalate 2.54
    ethyl propionate 2.46
    nitromethane 25.1
    1,2-diethoxyethane 3.47
    benzonitrile 2.96
    trioctyl phosphate 1.73
    1-bromopropane 1.42
    gamma-valerolactone 37.32
    n-decanol 1.0
    triethyl phosphate 1.64
    4-methyl-2-pentanol 0.83
    propionitrile 2.18
    vinylene carbonate 10.52
    1,1,2-trichlorotrifluoroethane 27.3
    DMS 4.65
    cumene 0.46
    2-octanol 1.17
    2-hexanone 3.46
    octyl acetate 1.97
    limonene 0.71
    1,2-dimethoxyethane 12.68
    ethyl orthosilicate 1.55
    tributyl phosphate 1.49
    diacetone alcohol 7.46
    N,N-dimethylaniline 2.14
    acrylonitrile 4.42
    aniline 2.94
    1,3-propanediol 8.89
    bromobenzene 1.92
    dibromomethane 4.84
    1,1,2,2-tetrachloroethane 10.99
    2-methyl-cyclohexyl acetate 2.99
    tetrabutyl urea 2.36
    diisobutyl methanol 0.54
    2-phenylethanol 4.57
    styrene 0.68
    dioctyl adipate 2.4
    dimethyl sulfate 13.12
    ethyl butyrate 2.27
    methyl lactate 9.29
    butyl lactate 6.04
    diethyl carbonate 1.65
    propanediol butyl ether 9.3
    triethyl orthoformate 2.19
    p-tert-butyltoluene 0.6
    methyl 4-tert-butylbenzoate 7.05
    morpholine 12.73
    tert-butylamine 0.7
    n-dodecanol 0.57
    dimethoxymethane 18.4
    ethylene carbonate 7.29
    cyrene 12.54
    2-ethoxyethyl acetate 9.36
    2-ethylhexyl acetate 2.06
    1,2,4-trichlorobenzene 4.17
    4-methylpyridine 5.39
    dibutyl ether 0.77
    2,6-dimethyl-4-heptanol 0.54
    DEF 7.05
    dimethyl isosorbide 11.04
    tetrachloroethylene 8.24
    eugenol 7.84
    triacetin 7.86
    span 80 7.46
    1,4-butanediol 3.88
    1,1-dichloroethane 3.97
    2-methyl-1-pentanol 1.48
    methyl formate 12.36
    2-methyl-1-butanol 1.57
    n-decane 0.08
    butyronitrile 1.7
    3,7-dimethyl-1-octanol 1.06
    1-chlorooctane 0.53
    1-chlorotetradecane 0.16
    n-nonane 0.07
    undecane 0.05
    tert-butylcyclohexane 0.06
    cyclooctane 0.05
    cyclopentanol 3.54
    tetrahydropyran 4.37
    tert-amyl methyl ether 1.35
    2,5,8-trioxanonane 10.48
    1-hexene 0.27
    2-isopropoxyethanol 6.93
    2,2,2-trifluoroethanol 12.07
    methyl butyrate 3.46

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction