Sodium anisate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    536-45-8

    Molecular formula
    C8H7NaO3

    SMILES
    COC1=CC=C(C=C1)C(=O)[O-].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Sweet 71.21%
    Vanilla 58.2%
    Phenolic 53.05%
    Balsamic 48.96%
    Powdery 45.07%
    Floral 38.78%
    Aromatic 38.58%
    Creamy 36.73%
    Spicy 34.94%
    Hay 34.44%

     

    Flavor
    Sweet 65.81%
    Balsam 47.79%
    Powdery 41.12%
    Balsamic 36.67%
    Faint 35.61%
    Hawthorn 34.77%
    Phenolic 33.33%
    Vanilla 32.8%
    Wintergreen 29.58%
    Honey 29.16%

     

    Odor impact est.
    Medium

  • Properties

    pKa est.
    4.29 (weak acid)

    Molecular weight
    174.13 g/mol

    Flash point

    • 123.29 ˚C est.

  • Synonyms

    • Sodium anisate
    • 536-45-8
    • sodium p-anisate
    • sodium p-methoxybenzoate
    • UNII-F9WFJ28MV9
    • F9WFJ28MV9
    • Benzoic acid, 4-methoxy-, sodium salt
    • EINECS 208-634-1
    • DTXSID00201818
    • RefChem:183779
    • SODIUM ANISATE [INCI]
    • DTXCID30124309
    • 208-634-1
    • sodium 4-methoxybenzoate
    • 4-Methoxybenzoic acid sodium salt
    • sodium;4-methoxybenzoate
    • CHEMBL1762657
    • 4-METHOXYBENZOIC ACID SODIUM
    • Natriumanisat
    • Sodium 4-anisate
    • sodium4-methoxybenzoate
    • SCHEMBL1043956
    • EBC-06281
    • AKOS003052768
    • AKOS022190815
    • FM70816
    • NS00080171
    • EN300-7835044
    • BENZOIC ACID, 4-METHOXY-, SODIUM SALT (1:1)
    • Q27277869
    • 536-45-8

  • Applications

    Sodium anisate (CAS 536-45-8) is the sodium salt of anisic acid, used mainly as a source of anisyl for synthesis in the fragrance industry; it serves as a fragrance ingredient in cosmetics and personal care; it is applied in household cleaning products for formulation solubility and stability; and it functions as an industrial intermediate in the production of anisyl derivatives for coatings, inks, and plastics.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 28.84
    methanol 33.54
    isopropanol 18.91
    water 0.54
    ethyl acetate 41.67
    n-propanol 20.22
    acetone 87.68
    n-butanol 17.04
    acetonitrile 30.0
    DMF 290.45
    toluene 9.35
    isobutanol 12.98
    1,4-dioxane 81.31
    methyl acetate 56.48
    THF 162.79
    2-butanone 62.06
    n-pentanol 17.99
    sec-butanol 19.93
    n-hexane 1.7
    ethylene glycol 15.2
    NMP 385.03
    cyclohexane 1.49
    DMSO 396.43
    n-butyl acetate 34.05
    n-octanol 6.5
    chloroform 26.58
    n-propyl acetate 35.8
    acetic acid 56.65
    dichloromethane 52.52
    cyclohexanone 64.05
    propylene glycol 16.37
    isopropyl acetate 29.95
    DMAc 257.21
    2-ethoxyethanol 78.84
    isopentanol 17.12
    n-heptane 1.21
    ethyl formate 30.93
    1,2-dichloroethane 57.51
    n-hexanol 14.83
    2-methoxyethanol 98.5
    isobutyl acetate 13.94
    tetrachloromethane 6.4
    n-pentyl acetate 18.04
    transcutol 406.07
    n-heptanol 7.77
    ethylbenzene 10.38
    MIBK 30.61
    2-propoxyethanol 60.65
    tert-butanol 31.97
    MTBE 38.3
    2-butoxyethanol 32.08
    propionic acid 35.32
    o-xylene 14.14
    formic acid 63.96
    diethyl ether 36.37
    m-xylene 9.86
    p-xylene 10.77
    chlorobenzene 22.55
    dimethyl carbonate 48.86
    n-octane 0.34
    formamide 172.66
    cyclopentanone 116.49
    2-pentanone 46.27
    anisole 68.66
    cyclopentyl methyl ether 54.89
    gamma-butyrolactone 153.84
    1-methoxy-2-propanol 76.62
    pyridine 61.41
    3-pentanone 41.27
    furfural 180.59
    n-dodecane 0.25
    diethylene glycol 65.27
    diisopropyl ether 11.64
    tert-amyl alcohol 36.21
    acetylacetone 81.51
    n-hexadecane 0.31
    acetophenone 72.09
    methyl propionate 50.4
    isopentyl acetate 30.41
    trichloroethylene 101.01
    n-nonanol 6.52
    cyclohexanol 15.01
    benzyl alcohol 40.98
    2-ethylhexanol 10.93
    isooctanol 6.68
    dipropyl ether 19.15
    1,2-dichlorobenzene 32.81
    ethyl lactate 30.98
    propylene carbonate 66.45
    n-methylformamide 117.31
    2-pentanol 14.73
    n-pentane 1.51
    1-propoxy-2-propanol 43.62
    1-methoxy-2-propyl acetate 72.38
    2-(2-methoxypropoxy) propanol 80.68
    mesitylene 7.58
    ε-caprolactone 66.11
    p-cymene 9.33
    epichlorohydrin 175.93
    1,1,1-trichloroethane 25.22
    2-aminoethanol 26.39
    morpholine-4-carbaldehyde 259.39
    sulfolane 288.75
    2,2,4-trimethylpentane 1.67
    2-methyltetrahydrofuran 90.22
    n-hexyl acetate 24.27
    isooctane 0.92
    2-(2-butoxyethoxy)ethanol 78.89
    sec-butyl acetate 24.02
    tert-butyl acetate 53.57
    decalin 1.79
    glycerin 38.37
    diglyme 197.75
    acrylic acid 49.04
    isopropyl myristate 10.71
    n-butyric acid 29.54
    acetyl acetate 33.12
    di(2-ethylhexyl) phthalate 15.85
    ethyl propionate 34.15
    nitromethane 178.42
    1,2-diethoxyethane 69.68
    benzonitrile 31.81
    trioctyl phosphate 8.33
    1-bromopropane 18.47
    gamma-valerolactone 166.31
    n-decanol 4.62
    triethyl phosphate 25.12
    4-methyl-2-pentanol 10.11
    propionitrile 18.9
    vinylene carbonate 54.76
    1,1,2-trichlorotrifluoroethane 123.06
    DMS 52.98
    cumene 8.63
    2-octanol 4.65
    2-hexanone 37.08
    octyl acetate 13.77
    limonene 13.78
    1,2-dimethoxyethane 129.66
    ethyl orthosilicate 21.04
    tributyl phosphate 14.29
    diacetone alcohol 72.19
    N,N-dimethylaniline 51.77
    acrylonitrile 36.45
    aniline 30.35
    1,3-propanediol 31.34
    bromobenzene 17.44
    dibromomethane 26.18
    1,1,2,2-tetrachloroethane 68.52
    2-methyl-cyclohexyl acetate 30.25
    tetrabutyl urea 21.35
    diisobutyl methanol 7.72
    2-phenylethanol 32.37
    styrene 15.06
    dioctyl adipate 26.08
    dimethyl sulfate 128.82
    ethyl butyrate 31.6
    methyl lactate 48.51
    butyl lactate 23.44
    diethyl carbonate 26.53
    propanediol butyl ether 36.01
    triethyl orthoformate 28.1
    p-tert-butyltoluene 9.4
    methyl 4-tert-butylbenzoate 49.67
    morpholine 102.23
    tert-butylamine 16.6
    n-dodecanol 3.27
    dimethoxymethane 116.89
    ethylene carbonate 33.78
    cyrene 96.61
    2-ethoxyethyl acetate 49.48
    2-ethylhexyl acetate 23.6
    1,2,4-trichlorobenzene 45.27
    4-methylpyridine 58.67
    dibutyl ether 11.86
    2,6-dimethyl-4-heptanol 7.72
    DEF 91.04
    dimethyl isosorbide 147.35
    tetrachloroethylene 48.05
    eugenol 51.51
    triacetin 61.25
    span 80 39.92
    1,4-butanediol 17.0
    1,1-dichloroethane 26.48
    2-methyl-1-pentanol 18.86
    methyl formate 83.12
    2-methyl-1-butanol 17.33
    n-decane 0.48
    butyronitrile 16.13
    3,7-dimethyl-1-octanol 9.55
    1-chlorooctane 3.76
    1-chlorotetradecane 1.43
    n-nonane 0.43
    undecane 0.34
    tert-butylcyclohexane 1.67
    cyclooctane 0.69
    cyclopentanol 23.8
    tetrahydropyran 40.6
    tert-amyl methyl ether 38.48
    2,5,8-trioxanonane 145.65
    1-hexene 6.8
    2-isopropoxyethanol 51.16
    2,2,2-trifluoroethanol 38.91
    methyl butyrate 44.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction