Sodium 2-(4-methoxyphenoxy)propanoate

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  • Identifiers

    CAS number
    150436-68-3

    Molecular formula
    C10H11NaO4

    SMILES
    CC(C(=O)[O-])OC1=CC=C(C=C1)OC.[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 60.81%
    Vanilla 56.66%
    Creamy 47.7%
    Caramellic 36.18%
    Milky 35.3%
    Powdery 33.53%
    Fruity 28.24%
    Buttery 27.74%
    Floral 26.94%
    Balsamic 26.69%

     

    Flavor
    Fruity 34.5%
    Odorless 32.04%
    Bland 26.06%
    Sweet 25.65%
    Bitter 25.23%
    Mild 23.35%
    Creamy 23.27%
    Powdery 21.12%
    Very mild 20.62%
    Sweet-like 20.27%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.21 (weak acid)

    Molecular weight
    218.18 g/mol

    Flash point

    • 131.97 ˚C est.

    Solubility expt.

    • Soluble in water and propylene glycol, slightly soluble in fat
    • Miscible at room temperature (in ethanol)

  • Synonyms

    • Sodium 2-(4-methoxyphenoxy)propanoate
    • 150436-68-3
    • lactisole
    • Envision
    • FEMA No. 3773
    • 150767-88-7
    • UNII-ZU3D90W5GZ
    • ZU3D90W5GZ
    • sodium;2-(4-methoxyphenoxy)propanoate
    • Propanoic acid, 2-(4-methoxyphenoxy)-, sodium salt (1:1)
    • SODIUM 2-(4-METHOXYPHENOXY) PROPIONATE
    • Sodium 2-(4-methoxyphenoxy)propionate
    • MFCD07783974
    • Sodium 2-(4-methoxyphenoxy)propanoic acid
    • DTXSID60934059
    • LACTISOLE SODIUM SALT [MI]
    • Sodium2-(4-methoxyphenoxy)propanoate
    • SODIUM 2-(4-METHOXYPHENOXY)PROPANOATE [FHFI]
    • Lactisole sodium
    • Propanoic acid, 2-(4-methoxyphenoxy)-, sodium salt
    • LACTISOLE SODIUM SALT
    • SCHEMBL333239
    • CHEMBL3715108
    • SKORRGYRKQDXRS-UHFFFAOYSA-M
    • DTXCID501362713
    • HY-W030796A
    • AKOS016014267
    • FS35587
    • AS-70147
    • DA-67658
    • SY127593
    • CS-0079817
    • F20512
    • EN300-18673466
    • (-)-2-(4-methoxyphenoxy)propionic acid sodium salt
    • Q2813794
    • (-)-2-(4-methoxyphenoxy) propionic acid sodium salt
    • ( inverted exclamation markA)-2-(p-Methoxyphenoxy)propionic aci
    • PROPANOIC ACID, 2-(4-METHOXYPHENOXY)-, SODIUM SALT, (+/-)-
    • 604-737-4
    • 924-065-8

  • Applications

    Sodium 2-(4-methoxyphenoxy)propanoate, CAS 150436-68-3, is a propanoate salt bearing an anisyl ether group and is commonly considered a building block for specialty chemicals in fragrance and related industrial sectors; it may function as an anionic surfactant or co-solvent in formulations for cosmetics, personal care, and household products; it can serve as an intermediate or building block for fragrance compounds, specialty polymers, or plasticizers; it is also considered as a processing aid or additive in coatings and inks; use is subject to local regulations and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 53.93
    methanol 76.47
    isopropanol 36.99
    water 1.32
    ethyl acetate 167.92
    n-propanol 31.12
    acetone 197.0
    n-butanol 27.44
    acetonitrile 115.89
    DMF 282.28
    toluene 24.65
    isobutanol 22.65
    1,4-dioxane 196.62
    methyl acetate 171.24
    THF 265.97
    2-butanone 106.16
    n-pentanol 30.47
    sec-butanol 33.16
    n-hexane 2.99
    ethylene glycol 36.47
    NMP 253.95
    cyclohexane 2.77
    DMSO 539.66
    n-butyl acetate 74.56
    n-octanol 17.91
    chloroform 87.79
    n-propyl acetate 79.65
    acetic acid 117.1
    dichloromethane 183.62
    cyclohexanone 98.92
    propylene glycol 22.36
    isopropyl acetate 80.7
    DMAc 360.85
    2-ethoxyethanol 157.86
    isopentanol 31.35
    n-heptane 3.64
    ethyl formate 73.63
    1,2-dichloroethane 137.46
    n-hexanol 25.05
    2-methoxyethanol 185.75
    isobutyl acetate 39.97
    tetrachloromethane 9.75
    n-pentyl acetate 33.4
    transcutol 362.18
    n-heptanol 14.74
    ethylbenzene 26.01
    MIBK 51.78
    2-propoxyethanol 90.86
    tert-butanol 112.86
    MTBE 97.82
    2-butoxyethanol 45.2
    propionic acid 56.16
    o-xylene 33.79
    formic acid 98.19
    diethyl ether 76.18
    m-xylene 26.07
    p-xylene 35.05
    chlorobenzene 39.61
    dimethyl carbonate 94.53
    n-octane 2.72
    formamide 242.05
    cyclopentanone 163.03
    2-pentanone 74.2
    anisole 87.4
    cyclopentyl methyl ether 82.01
    gamma-butyrolactone 261.14
    1-methoxy-2-propanol 110.06
    pyridine 90.87
    3-pentanone 71.01
    furfural 213.01
    n-dodecane 3.0
    diethylene glycol 118.18
    diisopropyl ether 25.92
    tert-amyl alcohol 79.28
    acetylacetone 165.34
    n-hexadecane 3.39
    acetophenone 87.36
    methyl propionate 124.15
    isopentyl acetate 65.8
    trichloroethylene 191.69
    n-nonanol 17.98
    cyclohexanol 29.78
    benzyl alcohol 55.68
    2-ethylhexanol 22.85
    isooctanol 14.39
    dipropyl ether 37.49
    1,2-dichlorobenzene 50.61
    ethyl lactate 44.64
    propylene carbonate 110.67
    n-methylformamide 129.32
    2-pentanol 24.85
    n-pentane 2.1
    1-propoxy-2-propanol 62.11
    1-methoxy-2-propyl acetate 103.02
    2-(2-methoxypropoxy) propanol 92.81
    mesitylene 20.33
    ε-caprolactone 105.88
    p-cymene 19.79
    epichlorohydrin 280.78
    1,1,1-trichloroethane 73.27
    2-aminoethanol 41.46
    morpholine-4-carbaldehyde 301.62
    sulfolane 307.06
    2,2,4-trimethylpentane 3.53
    2-methyltetrahydrofuran 142.11
    n-hexyl acetate 47.33
    isooctane 2.2
    2-(2-butoxyethoxy)ethanol 98.63
    sec-butyl acetate 55.17
    tert-butyl acetate 100.24
    decalin 5.34
    glycerin 60.94
    diglyme 215.17
    acrylic acid 60.67
    isopropyl myristate 25.42
    n-butyric acid 59.8
    acetyl acetate 115.67
    di(2-ethylhexyl) phthalate 26.96
    ethyl propionate 77.25
    nitromethane 390.66
    1,2-diethoxyethane 117.3
    benzonitrile 58.03
    trioctyl phosphate 17.7
    1-bromopropane 41.13
    gamma-valerolactone 239.67
    n-decanol 15.51
    triethyl phosphate 47.94
    4-methyl-2-pentanol 20.25
    propionitrile 60.83
    vinylene carbonate 101.01
    1,1,2-trichlorotrifluoroethane 152.37
    DMS 97.76
    cumene 20.47
    2-octanol 13.15
    2-hexanone 61.89
    octyl acetate 30.44
    limonene 25.09
    1,2-dimethoxyethane 263.21
    ethyl orthosilicate 44.27
    tributyl phosphate 28.57
    diacetone alcohol 106.16
    N,N-dimethylaniline 66.19
    acrylonitrile 88.84
    aniline 41.16
    1,3-propanediol 58.64
    bromobenzene 40.07
    dibromomethane 85.15
    1,1,2,2-tetrachloroethane 129.74
    2-methyl-cyclohexyl acetate 53.01
    tetrabutyl urea 40.01
    diisobutyl methanol 20.39
    2-phenylethanol 46.8
    styrene 30.5
    dioctyl adipate 45.55
    dimethyl sulfate 183.42
    ethyl butyrate 65.15
    methyl lactate 63.92
    butyl lactate 32.27
    diethyl carbonate 58.85
    propanediol butyl ether 44.16
    triethyl orthoformate 51.81
    p-tert-butyltoluene 19.85
    methyl 4-tert-butylbenzoate 65.78
    morpholine 184.69
    tert-butylamine 46.6
    n-dodecanol 13.58
    dimethoxymethane 201.67
    ethylene carbonate 80.9
    cyrene 93.23
    2-ethoxyethyl acetate 75.17
    2-ethylhexyl acetate 51.53
    1,2,4-trichlorobenzene 64.55
    4-methylpyridine 86.55
    dibutyl ether 35.77
    2,6-dimethyl-4-heptanol 20.39
    DEF 123.39
    dimethyl isosorbide 173.19
    tetrachloroethylene 75.48
    eugenol 62.22
    triacetin 89.14
    span 80 49.17
    1,4-butanediol 31.94
    1,1-dichloroethane 72.32
    2-methyl-1-pentanol 34.96
    methyl formate 133.53
    2-methyl-1-butanol 26.92
    n-decane 4.24
    butyronitrile 45.04
    3,7-dimethyl-1-octanol 22.74
    1-chlorooctane 14.78
    1-chlorotetradecane 8.85
    n-nonane 3.71
    undecane 3.49
    tert-butylcyclohexane 5.0
    cyclooctane 2.1
    cyclopentanol 37.5
    tetrahydropyran 84.09
    tert-amyl methyl ether 83.1
    2,5,8-trioxanonane 183.34
    1-hexene 12.89
    2-isopropoxyethanol 93.56
    2,2,2-trifluoroethanol 75.16
    methyl butyrate 88.03

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction