Shionone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    10376-48-4

    Molecular formula
    C30H50O

    SMILES
    C[C@H]1C(=O)CC[C@@H]2[C@@]1(CC[C@H]3[C@]2(CC[C@@]4([C@@]3(CC[C@@](C4)(C)CCC=C(C)C)C)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 86.51%
    Amber 57.74%
    Dry 52.68%
    Musk 44.64%
    Cedar 43.46%
    Sandalwood 40.13%
    Sweet 37.09%
    Powdery 35.91%
    Spicy 34.63%
    Vetiver 34.24%

     

    Flavor
    Woody 60.91%
    Camphor 36.12%
    Wood 34.22%
    Dry 34.12%
    Pine 33.54%
    Sweet 32.78%
    Fresh 27.78%
    Earthy 27.75%
    Balsam 26.36%
    Fir needle 25.24%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    10.0

    pKa est.
    7.84 (neutral)

    Molecular weight
    426.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    503°C

    Flash point

    • 228.83 ˚C est.

  • Synonyms

    • Shionone
    • 10376-48-4
    • Shionon
    • D:A-Friedo-18,19-secolup-19-en-3-one
    • BT0AMD31UB
    • (1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-en-1-yl)hexadecahydrochrysen-2(1H)-one
    • CHEBI:63459
    • (1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-enyl)-1,3,4,4a,5,6,7,9,10,10b,11,12-dodecahydrochrysen-2-one
    • RefChem:182742
    • MFCD06799428
    • UNII-BT0AMD31UB
    • SHIONONE [MI]
    • orb1301327
    • SCHEMBL27803620
    • HY-N0829
    • AKOS030573546
    • EBC-617302
    • FS73856
    • (1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-en-1-yl)-octadecahydrochrysen-2-one
    • AC-35082
    • D-Homo-5.alpha.-androstan-17-one, 3.alpha.,5,8,17a.beta.-tetramethyl-3-(4-methyl-3-pentenyl)-
    • MS-27538
    • CS-0009860
    • C17966
    • 376S484
    • Q27132632
    • 2(1H)-CHRYSENONE, HEXADECAHYDRO-1,4B,6A,8,10A,12A-HEXAMETHYL-8-(4-METHYL-3-PENTEN-1-YL)-, (1R,4AS,4BS,6AS,8R,10AR,10BS,12AS)-
    • 2(1H)-CHRYSENONE, HEXADECAHYDRO-1,4B,6A,8,10A,12A-HEXAMETHYL-8-(4-METHYL-3-PENTENYL)-, (1R-(1.ALPHA.,4A.BETA.,4B.ALPHA.,6A.BETA.,8.BETA.,10A.ALPHA.,10B.BETA.,12A.ALPHA.))-
    • 10376-48-4

  • Applications

    Shionone (CAS 10376-48-4) is a fragrant terpenoid compound used primarily in fragrance and cosmetic applications. In practice, it is employed as an odorant and can function as a fragrance fixative in perfume formulations and personal care products. It is also considered for use in household and cleaning products to impart fragrance. In industrial manufacturing, Shionone may act as an intermediate or building block for the synthesis of other fragrance-related compounds. Additionally, it can be used as a fragrance additive for plastics, coatings, and inks to adjust scent profiles.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 12.94
    methanol 3.63
    isopropanol 13.67
    water 0.01
    ethyl acetate 31.79
    n-propanol 23.79
    acetone 23.8
    n-butanol 27.96
    acetonitrile 6.28
    DMF 46.82
    toluene 84.99
    isobutanol 21.06
    1,4-dioxane 72.94
    methyl acetate 19.25
    THF 138.19
    2-butanone 35.37
    n-pentanol 20.03
    sec-butanol 14.7
    n-hexane 3.69
    ethylene glycol 0.66
    NMP 72.06
    cyclohexane 5.89
    DMSO 10.04
    n-butyl acetate 35.97
    n-octanol 14.29
    chloroform 93.58
    n-propyl acetate 24.88
    acetic acid 9.73
    dichloromethane 50.92
    cyclohexanone 66.78
    propylene glycol 2.31
    isopropyl acetate 38.5
    DMAc 69.39
    2-ethoxyethanol 23.76
    isopentanol 26.72
    n-heptane 3.6
    ethyl formate 8.76
    1,2-dichloroethane 32.64
    n-hexanol 29.33
    2-methoxyethanol 25.17
    isobutyl acetate 28.83
    tetrachloromethane 16.84
    n-pentyl acetate 43.26
    transcutol 106.27
    n-heptanol 23.05
    ethylbenzene 29.63
    MIBK 39.44
    2-propoxyethanol 71.8
    tert-butanol 14.49
    MTBE 27.75
    2-butoxyethanol 51.51
    propionic acid 11.05
    o-xylene 38.7
    formic acid 1.9
    diethyl ether 43.35
    m-xylene 56.84
    p-xylene 30.44
    chlorobenzene 53.13
    dimethyl carbonate 16.33
    n-octane 1.09
    formamide 3.06
    cyclopentanone 70.8
    2-pentanone 41.34
    anisole 54.13
    cyclopentyl methyl ether 72.28
    gamma-butyrolactone 53.79
    1-methoxy-2-propanol 41.99
    pyridine 75.77
    3-pentanone 37.8
    furfural 45.72
    n-dodecane 0.52
    diethylene glycol 17.77
    diisopropyl ether 18.5
    tert-amyl alcohol 13.67
    acetylacetone 46.84
    n-hexadecane 0.67
    acetophenone 43.15
    methyl propionate 32.38
    isopentyl acetate 44.99
    trichloroethylene 80.65
    n-nonanol 17.18
    cyclohexanol 25.29
    benzyl alcohol 29.59
    2-ethylhexanol 21.03
    isooctanol 21.22
    dipropyl ether 38.74
    1,2-dichlorobenzene 49.12
    ethyl lactate 13.4
    propylene carbonate 30.28
    n-methylformamide 10.33
    2-pentanol 20.36
    n-pentane 4.44
    1-propoxy-2-propanol 62.12
    1-methoxy-2-propyl acetate 69.3
    2-(2-methoxypropoxy) propanol 42.54
    mesitylene 29.01
    ε-caprolactone 64.28
    p-cymene 20.71
    epichlorohydrin 67.43
    1,1,1-trichloroethane 43.2
    2-aminoethanol 4.17
    morpholine-4-carbaldehyde 87.67
    sulfolane 49.39
    2,2,4-trimethylpentane 2.82
    2-methyltetrahydrofuran 64.32
    n-hexyl acetate 43.99
    isooctane 2.7
    2-(2-butoxyethoxy)ethanol 55.38
    sec-butyl acetate 26.54
    tert-butyl acetate 47.61
    decalin 4.62
    glycerin 4.27
    diglyme 101.68
    acrylic acid 8.22
    isopropyl myristate 17.85
    n-butyric acid 25.86
    acetyl acetate 24.56
    di(2-ethylhexyl) phthalate 22.0
    ethyl propionate 27.82
    nitromethane 16.3
    1,2-diethoxyethane 46.63
    benzonitrile 28.86
    trioctyl phosphate 14.6
    1-bromopropane 28.27
    gamma-valerolactone 110.77
    n-decanol 10.47
    triethyl phosphate 20.74
    4-methyl-2-pentanol 18.32
    propionitrile 15.22
    vinylene carbonate 30.47
    1,1,2-trichlorotrifluoroethane 35.3
    DMS 32.48
    cumene 19.39
    2-octanol 12.79
    2-hexanone 30.14
    octyl acetate 20.48
    limonene 23.06
    1,2-dimethoxyethane 51.65
    ethyl orthosilicate 24.05
    tributyl phosphate 14.33
    diacetone alcohol 38.72
    N,N-dimethylaniline 40.87
    acrylonitrile 13.08
    aniline 46.96
    1,3-propanediol 11.4
    bromobenzene 62.78
    dibromomethane 37.07
    1,1,2,2-tetrachloroethane 64.62
    2-methyl-cyclohexyl acetate 37.41
    tetrabutyl urea 21.5
    diisobutyl methanol 15.16
    2-phenylethanol 43.04
    styrene 32.05
    dioctyl adipate 27.01
    dimethyl sulfate 22.55
    ethyl butyrate 33.44
    methyl lactate 14.03
    butyl lactate 32.45
    diethyl carbonate 19.95
    propanediol butyl ether 29.38
    triethyl orthoformate 36.49
    p-tert-butyltoluene 20.81
    methyl 4-tert-butylbenzoate 58.11
    morpholine 84.69
    tert-butylamine 12.34
    n-dodecanol 6.35
    dimethoxymethane 54.7
    ethylene carbonate 25.58
    cyrene 41.49
    2-ethoxyethyl acetate 60.45
    2-ethylhexyl acetate 39.81
    1,2,4-trichlorobenzene 62.83
    4-methylpyridine 76.36
    dibutyl ether 18.8
    2,6-dimethyl-4-heptanol 15.16
    DEF 46.41
    dimethyl isosorbide 82.07
    tetrachloroethylene 40.79
    eugenol 51.21
    triacetin 47.87
    span 80 36.91
    1,4-butanediol 4.36
    1,1-dichloroethane 34.61
    2-methyl-1-pentanol 19.75
    methyl formate 6.64
    2-methyl-1-butanol 24.57
    n-decane 1.55
    butyronitrile 18.89
    3,7-dimethyl-1-octanol 16.53
    1-chlorooctane 9.64
    1-chlorotetradecane 2.43
    n-nonane 1.32
    undecane 0.84
    tert-butylcyclohexane 4.11
    cyclooctane 2.91
    cyclopentanol 20.7
    tetrahydropyran 76.16
    tert-amyl methyl ether 25.71
    2,5,8-trioxanonane 58.14
    1-hexene 13.05
    2-isopropoxyethanol 25.13
    2,2,2-trifluoroethanol 5.07
    methyl butyrate 28.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction