Serrapeptase

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  • Identifiers

    CAS number
    37312-62-2

    Molecular formula
    C46H40N8O8

    SMILES
    C/1N2C(=O)C3=C(C(=O)C=CN3N(C2)C(C4=C(OC/C=C1)C=CN=C4)C5=CC=CC=C5)O.C/1N2C(=O)C3=C(C(=O)C=CN3N(C2)C(C4=C(OC/C=C1)C=CN=C4)C5=CC=CC=C5)O

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 41.82%
    Burnt 27.93%
    Nutty 27.37%
    Sweet 26.3%
    Bitter 25.98%
    Roasted 25.04%
    Spicy 22.61%
    Vanilla 21.26%
    Popcorn 21.21%
    Caramellic 20.92%

     

    Flavor
    Bitter 95.42%
    Cedarleaf 19.67%
    Lovage 19.27%
    Very strong 18.9%
    Nitrile 18.85%
    Cereal 18.82%
    Sweet-like 18.78%
    Indole 18.76%
    Odorless 18.71%
    Alkaline 18.27%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.88 (weak acid)

    Molecular weight
    832.9 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    672°C

    Flash point

    • 300.4 ˚C est.

  • Synonyms

    • Serratiopeptidase
    • 37312-62-2
    • Serrapeptase (JAN)
    • SERRAPEPTASE [JAN]
    • Serrapeptasum (INN-Latin)
    • Serrapeptasum [INN-Latin]
    • Serrapeptasa (INN-Spanish)
    • Serrapeptasa [INN-Spanish]
    • Serrapeptase
    • Dasen
    • serrapeptasi
    • Aniflazime
    • Serralysin
    • Serrapeptasa
    • Serrapeptasum
    • Aniflazym
    • Irzaim
    • Peptizyme SP
    • Serratio peptidase
    • Irzaim (TN)
    • Serrapeptase [INN]
    • RefChem:884940
    • SERRALYSIN [INCI]
    • SERRAPEPTASE [JP]
    • NL053ABE4J
    • SERRAPEPTASE [WHO-DD]
    • Serrapeptase [INN:DCF:JAN]
    • Serratia extracellular proteinase
    • DTXSID001021788
    • EINECS 253-457-5
    • 70851-98-8
    • 95077-02-4
    • DA-77806
    • (11Z)-17-hydroxy-2-phenyl-9-oxa-1,5,14,21-tetrazatetracyclo[12.7.1.03,8.016,21]docosa-3(8),4,6,11,16,19-hexaene-15,18-dione
    • 37312-62-2

  • Applications

    Serrapeptase (CAS 37312-62-2) is a proteolytic enzyme derived from biological sources and is used as a biocatalyst across several industries: in cosmetics/personal care for protein processing in specialized formulations; in food processing for controlled proteolysis and protein modification; in industrial manufacturing as a biocatalyst for peptide hydrolysis; in cleaning and household products as a proteolytic component in enzyme-based cleaners; in waste management and agricultural processing to degrade protein-rich residues; and in pharmaceutical manufacturing at a research stage as a biocatalyst for peptide processing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.18
    methanol 4.58
    isopropanol 2.57
    water 0.12
    ethyl acetate 19.23
    n-propanol 3.3
    acetone 27.44
    n-butanol 3.05
    acetonitrile 15.79
    DMF 26.76
    toluene 10.36
    isobutanol 2.55
    1,4-dioxane 13.46
    methyl acetate 20.18
    THF 35.66
    2-butanone 26.23
    n-pentanol 3.16
    sec-butanol 2.55
    n-hexane 0.12
    ethylene glycol 5.62
    NMP 39.18
    cyclohexane 0.38
    DMSO 44.3
    n-butyl acetate 6.95
    n-octanol 1.12
    chloroform 23.91
    n-propyl acetate 8.5
    acetic acid 46.26
    dichloromethane 27.38
    cyclohexanone 37.37
    propylene glycol 3.77
    isopropyl acetate 8.7
    DMAc 67.21
    2-ethoxyethanol 12.81
    isopentanol 3.0
    n-heptane 0.23
    ethyl formate 18.34
    1,2-dichloroethane 17.72
    n-hexanol 2.7
    2-methoxyethanol 21.19
    isobutyl acetate 4.68
    tetrachloromethane 3.9
    n-pentyl acetate 5.43
    transcutol 22.08
    n-heptanol 1.96
    ethylbenzene 2.63
    MIBK 7.35
    2-propoxyethanol 13.56
    tert-butanol 2.47
    MTBE 1.46
    2-butoxyethanol 8.78
    propionic acid 14.74
    o-xylene 4.77
    formic acid 27.7
    diethyl ether 3.42
    m-xylene 4.93
    p-xylene 3.87
    chlorobenzene 11.51
    dimethyl carbonate 19.46
    n-octane 0.11
    formamide 33.92
    cyclopentanone 46.07
    2-pentanone 15.24
    anisole 4.58
    cyclopentyl methyl ether 8.59
    gamma-butyrolactone 51.99
    1-methoxy-2-propanol 13.09
    pyridine 35.17
    3-pentanone 14.76
    furfural 52.12
    n-dodecane 0.13
    diethylene glycol 20.27
    diisopropyl ether 0.91
    tert-amyl alcohol 2.15
    acetylacetone 27.68
    n-hexadecane 0.15
    acetophenone 11.67
    methyl propionate 19.78
    isopentyl acetate 6.0
    trichloroethylene 47.98
    n-nonanol 1.38
    cyclohexanol 5.01
    benzyl alcohol 10.12
    2-ethylhexanol 2.28
    isooctanol 1.78
    dipropyl ether 2.55
    1,2-dichlorobenzene 9.39
    ethyl lactate 8.95
    propylene carbonate 26.02
    n-methylformamide 19.39
    2-pentanol 1.93
    n-pentane 0.15
    1-propoxy-2-propanol 7.36
    1-methoxy-2-propyl acetate 12.68
    2-(2-methoxypropoxy) propanol 8.37
    mesitylene 2.16
    ε-caprolactone 28.08
    p-cymene 2.38
    epichlorohydrin 48.53
    1,1,1-trichloroethane 14.92
    2-aminoethanol 5.02
    morpholine-4-carbaldehyde 32.95
    sulfolane 57.23
    2,2,4-trimethylpentane 0.11
    2-methyltetrahydrofuran 12.14
    n-hexyl acetate 4.22
    isooctane 0.07
    2-(2-butoxyethoxy)ethanol 10.88
    sec-butyl acetate 5.41
    tert-butyl acetate 5.67
    decalin 0.25
    glycerin 13.07
    diglyme 19.58
    acrylic acid 23.67
    isopropyl myristate 2.24
    n-butyric acid 16.05
    acetyl acetate 19.11
    di(2-ethylhexyl) phthalate 4.4
    ethyl propionate 9.05
    nitromethane 71.84
    1,2-diethoxyethane 5.99
    benzonitrile 16.28
    trioctyl phosphate 2.95
    1-bromopropane 5.01
    gamma-valerolactone 55.95
    n-decanol 1.18
    triethyl phosphate 5.63
    4-methyl-2-pentanol 1.4
    propionitrile 13.05
    vinylene carbonate 29.87
    1,1,2-trichlorotrifluoroethane 53.4
    DMS 9.8
    cumene 1.78
    2-octanol 1.09
    2-hexanone 9.33
    octyl acetate 3.16
    limonene 2.55
    1,2-dimethoxyethane 15.08
    ethyl orthosilicate 4.5
    tributyl phosphate 3.69
    diacetone alcohol 11.71
    N,N-dimethylaniline 3.84
    acrylonitrile 23.91
    aniline 13.68
    1,3-propanediol 8.85
    bromobenzene 10.43
    dibromomethane 13.57
    1,1,2,2-tetrachloroethane 28.76
    2-methyl-cyclohexyl acetate 6.01
    tetrabutyl urea 5.68
    diisobutyl methanol 1.32
    2-phenylethanol 9.71
    styrene 3.26
    dioctyl adipate 4.64
    dimethyl sulfate 28.09
    ethyl butyrate 7.0
    methyl lactate 17.58
    butyl lactate 6.66
    diethyl carbonate 6.59
    propanediol butyl ether 5.78
    triethyl orthoformate 5.4
    p-tert-butyltoluene 1.82
    methyl 4-tert-butylbenzoate 7.82
    morpholine 14.31
    tert-butylamine 0.94
    n-dodecanol 1.0
    dimethoxymethane 19.18
    ethylene carbonate 24.31
    cyrene 17.12
    2-ethoxyethyl acetate 10.45
    2-ethylhexyl acetate 4.81
    1,2,4-trichlorobenzene 14.43
    4-methylpyridine 23.07
    dibutyl ether 1.54
    2,6-dimethyl-4-heptanol 1.32
    DEF 17.97
    dimethyl isosorbide 17.03
    tetrachloroethylene 22.66
    eugenol 9.7
    triacetin 8.8
    span 80 6.54
    1,4-butanediol 4.6
    1,1-dichloroethane 13.04
    2-methyl-1-pentanol 3.21
    methyl formate 23.56
    2-methyl-1-butanol 2.8
    n-decane 0.17
    butyronitrile 9.03
    3,7-dimethyl-1-octanol 1.48
    1-chlorooctane 0.74
    1-chlorotetradecane 0.47
    n-nonane 0.13
    undecane 0.15
    tert-butylcyclohexane 0.15
    cyclooctane 0.17
    cyclopentanol 6.46
    tetrahydropyran 8.66
    tert-amyl methyl ether 1.84
    2,5,8-trioxanonane 15.94
    1-hexene 0.67
    2-isopropoxyethanol 7.77
    2,2,2-trifluoroethanol 27.21
    methyl butyrate 10.92

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction