Semduramicin Sodium
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Identifiers
CAS number
119068-77-8Molecular formula
C45H75NaO16SMILES
C[C@H]1C[C@H]([C@@](O[C@@H]1[C@H]2C[C@@H]([C@@H](O2)[C@@]3(CC[C@@H](O3)[C@@]4(CC[C@@]5(O4)C[C@@H]([C@H]([C@H](O5)[C@@H](C)[C@H]6[C@@H]([C@H]([C@@H]([C@](O6)(CC(=O)[O-])O)C)O)OC)C)O)C)C)O[C@H]7CC[C@@H]([C@H](O7)C)OC)(C)O)C.[Na+]
Safety labels
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Odor profile
Fragrance Odorless 55.47% Milky 23.31% Sweet 23.01% Cooling 22.8% Mint 21.81% Creamy 21.74% Woody 18.34% Savory 17.8% Lactonic 17.68% Roasted 17.03% Flavor Bitter 41.48% Fatty 39.08% Metallic 24.92% Sweet-like 24.25% Odorless 23.56% Cedarleaf 21.82% Cauliflower 21.77% Bouillon 21.5% Minty 21.26% Mentholic 20.84% Odor impact est.
Low -
Properties
pKa est.
4.65 (weak acid)Molecular weight
895.1 g/molFlash point
- 124.85 ˚C est.
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Synonyms
- Semduramicin sodium
- Aviax
- Sodium semduramicin
- 119068-77-8
- Semduramicin sodium salt
- UNII-8B50X0IVEC
- UK-61689-2
- 8B50X0IVEC
- UK-61,689-2
- DTXSID601018105
- Lonomycin A, 23,27-didemethoxy-2,6,22-tridemethyl-5,11-di-O-demethyl-6-methoxy-22-((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-, monosodium salt, (3R,4S,5S,6R,7S,22S(2S,5S,6R))-
- (3R,4S,5S,6R,7S,22S)-23,27-Didemethoxy-2,6,22-tridemethyl-5,11-di-O-demethyl-6-methoxy-22-(((2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)lonomycin A, monosodium salt
- Aviax II
- (3R,4S,5S,6R,7S,22S)-23,27-Didemethoxy-2,6,22-tridemethyl-5,11-di-O-demethyl-6-methoxy-22-[[(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy]lonomycin A, monosodium salt
- UK 61689-2
- RefChem:57148
- Aviax Premix for Broiler Chickens
- DTXCID101476344
- Monosodium (2R,3S,4S,5R,6S)-tetrahydro-2,4-dihydroxy-6-((1R)-1-((2S,5R,7S,8R,9S)-9-hydroxy-2,8-dimethyl-2-((2R,5S)-tetrahydro-5-methyl-5-((2R,3S,5R)-tetrahydro-5-((2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl)-3-(((2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-2-furyl)-2-furyl)-1,6-dioxaspiro(4.5)dec-7-yl)ethyl)-5-methoxy-3-methyl-2H-pyran-2-acetate
- Semduramicin sodium [USAN]
- Semduramicin (sodium)
- sodium;2-[(2R,3S,4S,5R,6S)-2,4-dihydroxy-6-[(1R)-1-[(2S,5R,7S,8R,9S)-7-hydroxy-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6S)-6-hydroxy-3,5,6-trimethyloxan-2-yl]-3-[(2S,5S,6R)-5-methoxy-6-methyloxan-2-yl]oxyoxolan-2-yl]-5-methyloxolan-2-yl]-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]ethyl]-5-methoxy-3-methyloxan-2-yl]acetate
- 2H-Pyran-2-acetic acid, tetrahydro-2,4-dihydroxy-6-(1R)-1-(2S,5R,7S,8R,9S)-9-hydroxy-2,8-dimethyl-2-
- MSK8208Na-10A
- CHEMBL406100
- SEMDURAMICIN SODIUM [JAN]
- JXRFTGPGWGUBQB-LHOUOPCDSA-M
- 119068-77-8 (sodium)
- SEMDURAMICIN SODIUM SALT [MI]
- HY-122449A
- SEMDURAMICIN SODIUM [GREEN BOOK]
- CS-0093588
- Q27270130
- Semduramicin sodium Solution in Acetonitrile, 10ug/mL
- Lonomycin A, 23,27-didemethoxy-2,6,22-tridemethyl-5,11-di-O-demethyl-6-methoxy-22-((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-, monosodium salt, (3R,4S,5S,5S,6R,7S,22S(2S,5S,6R))-;
- Sodium {(2R,3S,4S,5R,6S)-2,4-dihydroxy-6-[(1R)-1-{(2S,5R,7S,8R,9S)-9-hydroxy-2-[(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6S)-6-hydroxy-3,5,6-trimethyloxan-2-yl]-3'-{[(2S,5S,6R)-5-methoxy-6-methyloxan-2-yl]oxy}-2-methyl[2,2'-bioxolan]-5-yl]-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl}ethyl]-5-methoxy-3-methyloxan-2-yl}acetate
- 119068-77-8
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Applications
Semduramicin sodium is a polyether ionophore antibiotic primarily used as a veterinary feed additive to prevent coccidiosis in poultry. It is incorporated into poultry diets as a coccidiostat to improve feed efficiency and growth performance in commercial production. It can also be used within broader animal nutrition programs for other poultry and livestock where ionophore additives are approved. Beyond production use, it is employed in research and development settings to study ionophore mechanisms and formulation performance. Use is subject to local regulations and approved species and dose limits.
gpt-5-nano
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Solubility @25˚C
Solvent Solubility (g/L) ethanol 235.27 methanol 635.65 isopropanol 62.31 water 1.25 ethyl acetate 106.28 n-propanol 167.01 acetone 222.87 n-butanol 71.42 acetonitrile 78.27 DMF 1171.53 toluene 12.0 isobutanol 54.91 1,4-dioxane 196.02 methyl acetate 131.55 THF 468.99 2-butanone 147.9 n-pentanol 35.5 sec-butanol 46.05 n-hexane 0.28 ethylene glycol 133.57 NMP 1146.79 cyclohexane 0.41 DMSO 1068.63 n-butyl acetate 31.33 n-octanol 13.46 chloroform 307.19 n-propyl acetate 44.1 acetic acid 1139.91 dichloromethane 330.95 cyclohexanone 175.16 propylene glycol 179.15 isopropyl acetate 45.22 DMAc 915.79 2-ethoxyethanol 312.64 isopentanol 25.72 n-heptane 0.24 ethyl formate 152.92 1,2-dichloroethane 126.6 n-hexanol 15.76 2-methoxyethanol 761.26 isobutyl acetate 21.64 tetrachloromethane 18.72 n-pentyl acetate 38.55 transcutol 238.71 n-heptanol 14.46 ethylbenzene 3.78 MIBK 31.68 2-propoxyethanol 232.17 tert-butanol 25.87 MTBE 15.55 2-butoxyethanol 129.59 propionic acid 234.19 o-xylene 5.73 formic acid 913.3 diethyl ether 31.11 m-xylene 5.8 p-xylene 4.33 chlorobenzene 31.5 dimethyl carbonate 167.95 n-octane 0.14 formamide 768.01 cyclopentanone 419.3 2-pentanone 90.51 anisole 29.17 cyclopentyl methyl ether 61.26 gamma-butyrolactone 726.81 1-methoxy-2-propanol 379.45 pyridine 197.76 3-pentanone 62.13 furfural 535.43 n-dodecane 0.14 diethylene glycol 236.01 diisopropyl ether 3.13 tert-amyl alcohol 24.64 acetylacetone 176.91 n-hexadecane 0.16 acetophenone 53.27 methyl propionate 157.26 isopentyl acetate 24.59 trichloroethylene 414.0 n-nonanol 13.21 cyclohexanol 24.68 benzyl alcohol 55.09 2-ethylhexanol 6.06 isooctanol 9.0 dipropyl ether 10.95 1,2-dichlorobenzene 32.86 ethyl lactate 62.45 propylene carbonate 246.82 n-methylformamide 804.94 2-pentanol 19.02 n-pentane 0.43 1-propoxy-2-propanol 94.47 1-methoxy-2-propyl acetate 92.61 2-(2-methoxypropoxy) propanol 79.74 mesitylene 2.19 ε-caprolactone 237.75 p-cymene 2.48 epichlorohydrin 660.77 1,1,1-trichloroethane 59.3 2-aminoethanol 287.49 morpholine-4-carbaldehyde 841.71 sulfolane 859.06 2,2,4-trimethylpentane 0.24 2-methyltetrahydrofuran 115.28 n-hexyl acetate 42.4 isooctane 0.12 2-(2-butoxyethoxy)ethanol 113.3 sec-butyl acetate 20.15 tert-butyl acetate 32.92 decalin 0.29 glycerin 359.44 diglyme 238.86 acrylic acid 342.53 isopropyl myristate 7.99 n-butyric acid 239.66 acetyl acetate 98.49 di(2-ethylhexyl) phthalate 21.4 ethyl propionate 43.33 nitromethane 1425.18 1,2-diethoxyethane 34.91 benzonitrile 38.97 trioctyl phosphate 13.74 1-bromopropane 31.19 gamma-valerolactone 1130.21 n-decanol 7.08 triethyl phosphate 19.23 4-methyl-2-pentanol 7.13 propionitrile 51.97 vinylene carbonate 281.56 1,1,2-trichlorotrifluoroethane 689.59 DMS 54.83 cumene 2.28 2-octanol 6.12 2-hexanone 35.68 octyl acetate 18.0 limonene 3.56 1,2-dimethoxyethane 234.09 ethyl orthosilicate 14.41 tributyl phosphate 14.85 diacetone alcohol 83.95 N,N-dimethylaniline 17.28 acrylonitrile 121.77 aniline 41.15 1,3-propanediol 271.07 bromobenzene 24.96 dibromomethane 124.83 1,1,2,2-tetrachloroethane 226.99 2-methyl-cyclohexyl acetate 21.81 tetrabutyl urea 22.24 diisobutyl methanol 2.57 2-phenylethanol 35.07 styrene 5.27 dioctyl adipate 24.59 dimethyl sulfate 361.67 ethyl butyrate 25.9 methyl lactate 214.2 butyl lactate 53.99 diethyl carbonate 19.59 propanediol butyl ether 107.13 triethyl orthoformate 21.91 p-tert-butyltoluene 2.27 methyl 4-tert-butylbenzoate 59.32 morpholine 329.01 tert-butylamine 5.46 n-dodecanol 3.68 dimethoxymethane 481.46 ethylene carbonate 185.31 cyrene 157.21 2-ethoxyethyl acetate 92.91 2-ethylhexyl acetate 16.79 1,2,4-trichlorobenzene 50.49 4-methylpyridine 116.04 dibutyl ether 6.57 2,6-dimethyl-4-heptanol 2.57 DEF 172.29 dimethyl isosorbide 137.11 tetrachloroethylene 139.09 eugenol 62.97 triacetin 94.94 span 80 70.01 1,4-butanediol 81.8 1,1-dichloroethane 76.03 2-methyl-1-pentanol 16.92 methyl formate 515.72 2-methyl-1-butanol 34.93 n-decane 0.32 butyronitrile 37.66 3,7-dimethyl-1-octanol 8.01 1-chlorooctane 3.32 1-chlorotetradecane 0.82 n-nonane 0.24 undecane 0.2 tert-butylcyclohexane 0.21 cyclooctane 0.16 cyclopentanol 67.06 tetrahydropyran 75.7 tert-amyl methyl ether 15.58 2,5,8-trioxanonane 127.48 1-hexene 2.0 2-isopropoxyethanol 109.42 2,2,2-trifluoroethanol 390.6 methyl butyrate 64.79 Scent© AI
| Maximum acceptable concentrations in the finished product (%) | |||
|---|---|---|---|
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Category 1
Products applied to the lips
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No restriction |
Category 7A
Rinse-off products applied to the hair with some hand contact
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No restriction |
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Category 2
Products applied to the axillae
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No restriction |
Category 7B
Leave-on products applied to the hair with some hand contact
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No restriction |
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Category 3
Products applied to the face/body using fingertips
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No restriction |
Category 8
Products with significant anogenital exposure
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No restriction |
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Category 4
Products related to fine fragrance
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No restriction |
Category 9
Products with body and hand exposure, primarily rinse off
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No restriction |
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Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
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No restriction |
Category 10A
Household care products with mostly hand contact
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No restriction |
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Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
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No restriction |
Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
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No restriction |
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Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
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No restriction |
Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
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No restriction |
|
Category 5D
Baby Creams, baby Oils and baby talc
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No restriction |
Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
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No restriction |
|
Category 6
Products with oral and lip exposure
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No restriction |
Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
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No restriction |