Selenium disulfide

Overview IFRA Request a quote

  • Identifiers

    CAS number
    7488-56-4

    Molecular formula
    S2Se

    SMILES
    S=[Se]=S

    Safety labels

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Pungent 66.48%
    Odorless 61.4%
    Sulfurous 50.9%
    Garlic 45.26%
    Radish 40.21%
    Alliaceous 34.63%
    Onion 30.04%
    Cooked 19.04%
    Burnt 18.7%
    Sharp 18.31%

     

    Flavor
    Bitter 57.43%
    Pungent 53.22%
    Mustard 47.36%
    Odorless 39.19%
    Sulfur 36.27%
    Garlic 29.16%
    Horseradish 26.84%
    Formyl 24.53%
    Rotten 23.36%
    Vinegar 22.55%

     

  • Properties

    pKa est.
    -19.06 (strong acid)

    Molecular weight
    143.1 g/mol

    Melting point expt.

    • less than 212 °F (NTP, 1992)
    • <100 °C

    Boiling point

    • Decomposes (NTP, 1992)
    • Decomposes

    Flash point

    • 61.06 ˚C est.

    Solubility expt.

    • 10 to 50 mg/mL at 68 °F (NTP, 1992)
    • Practically insoluble in water and organic solvents
    • Soluble in acids

  • Synonyms

    • Selenium disulfide
    • 7488-56-4
    • Selenium disulphide
    • Selenium(IV) disulfide
    • Selenium(IV) sulfide
    • Seledruff
    • Selenium sulfide, micronized
    • Selenium sulphide, micronized
    • Selenium(IV) sulphide
    • Selenium(IV) disulphide
    • Selenium sulfide (USP)
    • Selenium sulfide [USP]
    • MFCD00011227
    • Selenium sulphide (ses2)
    • Selsun Blue
    • Selenium sulfide (ses(sub 2))
    • Z69D9E381Q
    • Sebusan
    • Selenex
    • Selenix
    • Selukos
    • Lenium
    • Seleen
    • Sulfur selenide
    • Zeran
    • Sul-Blue
    • Sel-O-Rinse
    • Selenium sulfide (SeS2)
    • Selen(IV) sulfid
    • Selenium sulfide SeS2
    • Caswell No. 732A
    • Selendisulfid
    • Tersi
    • Selenii disulfidum
    • S2Se
    • HSDB 6367
    • Selenium(IV) Disulfide (1:2)
    • EINECS 231-303-8
    • UN2657
    • RCRA waste no. U205
    • EPA Pesticide Chemical Code 072003
    • UNII-Z69D9E381Q
    • Exsel (TN)
    • selenium (IV) sulfide
    • SCHEMBL158780
    • orb1941156
    • SELENIUM DISULFIDE [MI]
    • SELENIUM SULFIDE [HSDB]
    • CHEMBL1200680
    • DTXSID0042375
    • SELENIUM SULFIDE [VANDF]
    • SELENIUM DISULFIDE [HSDB]
    • SELENIUM SULFIDE [MART.]
    • CHEBI:135934
    • JNMWHTHYDQTDQZ-UHFFFAOYSA-N
    • SELENIUM SULFIDE [USP-RS]
    • SELENIUM SULFIDE [WHO-DD]
    • SELENIUM DISULFIDE [WHO-IP]
    • Bis(sulfanylidene)-lambda~4~-selane
    • SELENIUM SULFIDE [ORANGE BOOK]
    • DB00971
    • SELENIUM DISULFIDE [GREEN BOOK]
    • SELENIUM SULFIDE [USP MONOGRAPH]
    • SELENIUM DISULFIDE [EP MONOGRAPH]
    • SELENII DISULFIDUM [WHO-IP LATIN]
    • Selenium disulfide [UN2657] [Poison]
    • NS00078792
    • D05815
    • Q56249646
    • 7488-56-4

  • Applications

    Selenium disulfide (CAS 7488-56-4) is primarily used as an anti-dandruff active ingredient in shampoos and other hair-care products; it is also evaluated for dermatological topical formulations with antifungal properties; in industry, it can serve as an intermediate for the synthesis of other selenium-containing compounds and derivatives; in laboratory settings it is used as a reagent and selenium source for organoselenium chemistry and related analyses.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 99.5
    methanol 96.43
    isopropanol 91.15
    water 2.02
    ethyl acetate 141.98
    n-propanol 84.36
    acetone 258.99
    n-butanol 90.38
    acetonitrile 105.71
    DMF 574.34
    toluene 122.79
    isobutanol 67.04
    1,4-dioxane 307.11
    methyl acetate 136.63
    THF 529.58
    2-butanone 163.97
    n-pentanol 69.92
    sec-butanol 80.87
    n-hexane 38.88
    ethylene glycol 42.73
    NMP 527.21
    cyclohexane 68.85
    DMSO 578.54
    n-butyl acetate 118.82
    n-octanol 78.71
    chloroform 277.55
    n-propyl acetate 98.83
    acetic acid 131.58
    dichloromethane 234.9
    cyclohexanone 252.62
    propylene glycol 47.42
    isopropyl acetate 112.75
    DMAc 411.3
    2-ethoxyethanol 121.29
    isopentanol 79.94
    n-heptane 43.63
    ethyl formate 104.8
    1,2-dichloroethane 189.6
    n-hexanol 87.33
    2-methoxyethanol 218.09
    isobutyl acetate 74.67
    tetrachloromethane 98.73
    n-pentyl acetate 110.94
    transcutol 254.38
    n-heptanol 76.53
    ethylbenzene 68.28
    MIBK 121.27
    2-propoxyethanol 158.82
    tert-butanol 128.75
    MTBE 142.19
    2-butoxyethanol 124.34
    propionic acid 82.14
    o-xylene 94.31
    formic acid 47.23
    diethyl ether 158.19
    m-xylene 96.89
    p-xylene 89.64
    chlorobenzene 154.61
    dimethyl carbonate 124.56
    n-octane 26.54
    formamide 83.92
    cyclopentanone 362.67
    2-pentanone 170.32
    anisole 151.21
    cyclopentyl methyl ether 230.99
    gamma-butyrolactone 328.6
    1-methoxy-2-propanol 186.16
    pyridine 237.25
    3-pentanone 142.05
    furfural 335.42
    n-dodecane 23.76
    diethylene glycol 131.91
    diisopropyl ether 79.87
    tert-amyl alcohol 104.67
    acetylacetone 241.54
    n-hexadecane 26.64
    acetophenone 138.86
    methyl propionate 139.94
    isopentyl acetate 108.63
    trichloroethylene 288.94
    n-nonanol 74.58
    cyclohexanol 116.27
    benzyl alcohol 101.85
    2-ethylhexanol 72.99
    isooctanol 66.33
    dipropyl ether 110.78
    1,2-dichlorobenzene 149.97
    ethyl lactate 67.97
    propylene carbonate 187.51
    n-methylformamide 149.33
    2-pentanol 78.95
    n-pentane 43.84
    1-propoxy-2-propanol 130.9
    1-methoxy-2-propyl acetate 140.95
    2-(2-methoxypropoxy) propanol 126.79
    mesitylene 79.54
    ε-caprolactone 200.69
    p-cymene 62.46
    epichlorohydrin 313.86
    1,1,1-trichloroethane 202.45
    2-aminoethanol 59.15
    morpholine-4-carbaldehyde 396.96
    sulfolane 498.43
    2,2,4-trimethylpentane 29.11
    2-methyltetrahydrofuran 291.38
    n-hexyl acetate 125.88
    isooctane 25.52
    2-(2-butoxyethoxy)ethanol 151.44
    sec-butyl acetate 78.96
    tert-butyl acetate 152.2
    decalin 38.04
    glycerin 80.58
    diglyme 265.01
    acrylic acid 93.67
    isopropyl myristate 77.66
    n-butyric acid 116.53
    acetyl acetate 130.07
    di(2-ethylhexyl) phthalate 79.27
    ethyl propionate 95.66
    nitromethane 215.44
    1,2-diethoxyethane 142.34
    benzonitrile 125.18
    trioctyl phosphate 62.45
    1-bromopropane 123.8
    gamma-valerolactone 379.23
    n-decanol 62.89
    triethyl phosphate 74.56
    4-methyl-2-pentanol 59.66
    propionitrile 88.99
    vinylene carbonate 173.08
    1,1,2-trichlorotrifluoroethane 239.97
    DMS 118.49
    cumene 55.09
    2-octanol 67.21
    2-hexanone 114.76
    octyl acetate 93.5
    limonene 90.85
    1,2-dimethoxyethane 242.11
    ethyl orthosilicate 73.71
    tributyl phosphate 64.87
    diacetone alcohol 161.6
    N,N-dimethylaniline 129.49
    acrylonitrile 113.84
    aniline 125.8
    1,3-propanediol 90.43
    bromobenzene 168.56
    dibromomethane 180.92
    1,1,2,2-tetrachloroethane 257.76
    2-methyl-cyclohexyl acetate 97.21
    tetrabutyl urea 95.93
    diisobutyl methanol 61.37
    2-phenylethanol 110.25
    styrene 90.17
    dioctyl adipate 100.32
    dimethyl sulfate 240.71
    ethyl butyrate 102.43
    methyl lactate 100.63
    butyl lactate 86.96
    diethyl carbonate 77.91
    propanediol butyl ether 102.97
    triethyl orthoformate 89.76
    p-tert-butyltoluene 68.8
    methyl 4-tert-butylbenzoate 150.64
    morpholine 285.52
    tert-butylamine 91.05
    n-dodecanol 56.04
    dimethoxymethane 314.31
    ethylene carbonate 136.41
    cyrene 152.83
    2-ethoxyethyl acetate 135.87
    2-ethylhexyl acetate 100.18
    1,2,4-trichlorobenzene 177.88
    4-methylpyridine 225.46
    dibutyl ether 92.56
    2,6-dimethyl-4-heptanol 61.37
    DEF 212.91
    dimethyl isosorbide 241.25
    tetrachloroethylene 184.9
    eugenol 144.75
    triacetin 128.87
    span 80 134.48
    1,4-butanediol 45.66
    1,1-dichloroethane 170.43
    2-methyl-1-pentanol 66.25
    methyl formate 137.76
    2-methyl-1-butanol 71.98
    n-decane 31.83
    butyronitrile 101.25
    3,7-dimethyl-1-octanol 70.81
    1-chlorooctane 69.4
    1-chlorotetradecane 43.6
    n-nonane 30.88
    undecane 26.77
    tert-butylcyclohexane 35.99
    cyclooctane 35.46
    cyclopentanol 143.26
    tetrahydropyran 244.81
    tert-amyl methyl ether 131.81
    2,5,8-trioxanonane 210.24
    1-hexene 67.58
    2-isopropoxyethanol 95.35
    2,2,2-trifluoroethanol 73.59
    methyl butyrate 114.97

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction