Sarin

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  • Identifiers

    CAS number
    107-44-8

    Molecular formula
    C4H10FO2P

    SMILES
    CC(C)OP(=O)(C)F

  • Odor profile

    Fragrance
    Fruity 58.13%
    Odorless 33.12%
    Cheesy 27.45%
    Tropical 25.9%
    Sulfurous 24.23%
    Ethereal 21.97%
    Green 21.86%
    Fermented 20.92%
    Sour 20.85%
    Grape 20.73%

     

    Flavor
    Odorless 29.04%
    Sulfurous 25.56%
    Sulfury 24.81%
    Cheese 23.88%
    Fruity 23.16%
    Sour 22.56%
    Sharp 22.45%
    Stinky 21.21%
    Pungent 21.02%
    Acrid 20.9%

     

    Odor impact est.
    Medium

    Odor threshold

    • At a concentration of sarin under 1.5 mg/cu m, 8 of 15 people noted an odor, but gave no good description of it and did not think they would recognize it again.

  • Properties

    XLogP3-AA
    0.8

    pKa est.
    5.86 (weak acid)

    Molecular weight
    140.09 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Melting point expt.

    • -71 °F (EPA, 1998)
    • -57 °C

    Boiling point

    • 297 °F at 760 mmHg (EPA, 1998)
    • 147 °C at 760 mm Hg; 56 °C at 16 mm Hg

    Flash point

    • 41.7 ˚C est.
    • Non-flammable (EPA, 1998)

    Solubility expt.

    • Miscible with water /1X10+6 mg/L at 25 °C /

  • Synonyms

    • SARIN
    • Sarin II
    • Trilone 46
    • 107-44-8
    • IMPF
    • O-Isopropyl methylphosphonofluoridate
    • Isopropyl methylfluorophosphate
    • Isopropyl methylphosphonofluoridate
    • Sarin.
    • 2-[fluoro(methyl)phosphoryl]oxypropane
    • Isopropyl methanefluorophosphonate
    • Isopropoxymethylphosphoryl fluoride
    • Isopropyl-methyl-phosphoryl fluoride
    • Methylphosphonofluoridic acid isopropyl ester
    • CCRIS 3416
    • EA 1208
    • TL 1618
    • Isopropoxymethylphoshoryl fluoride
    • Phosphine oxide, fluoroisopropoxymethyl-
    • HSDB 6382
    • UNII-B4XG72QGFM
    • Phosphonofluoridic acid, methyl-, isopropyl ester
    • B4XG72QGFM
    • Phosphonofluoridic acid, methyl-, 1-methylethyl ester
    • T-144
    • Phosphoric acid, methylfluoro-, isopropyl ester
    • T-2106
    • Methylphosphonofluoridic acid 1-methylethyl ester
    • BRN 1750114
    • (+-)-Isopropyl methylphosphonofluoridate
    • Isopropyl methylfluorophosphonate
    • CHEBI:75701
    • Methlyfluorophosphonic acid isopropyl ester
    • Isopropylester kyseliny methylfluorfosfonove
    • Methylphosphonofluoride acid, isopropyl ester
    • 1-Methylethyl (+-)-methylphosphonofluoridate
    • Methylfluorphosphorsaeureisopropylester
    • GB
    • MFI
    • Phosphonofluoridic acid, methyl-, isopropyl ester, (+-)-
    • DTXSID0042371
    • O-Isopropyl methylfluorophosphonate
    • 4-04-00-03507 (Beilstein Handbook Reference)
    • 1-Methylethyl methylphosphonofluoridate
    • Phosphonofluoridic acid, P-methyl-, 1-methylethyl ester
    • Methylfluorophosphoric acid isopropyl ester
    • SARIN (MART.)
    • SARIN [MART.]
    • (+/-)-ISOPROPYL METHYLPHOSPHONOFLUORIDATE
    • PHOSPHONOFLUORIDIC ACID, METHYL-, ISOPROPYL ESTER, (+/-)-
    • Gas, Sarin
    • o-Isopropylmethyl Phosphonofluoridate
    • ortho-Isopropylmethyl Phosphonofluoridate
    • racemic sarin
    • Zarin
    • Methylfluorphosphorsaeureisopropylester [German]
    • S-Sarin
    • Agent GB
    • Isopropylester kyseliny methylfluorfosfonove [Czech]
    • o Isopropylmethyl Phosphonofluoridate
    • (RS)-sarin
    • Phosphonofluoridate, o-Isopropylmethyl
    • ortho Isopropylmethyl Phosphonofluoridate
    • (+-)-sarin
    • Phosphonofluoridate, ortho-Isopropylmethyl
    • SARIN [HSDB]
    • SARIN [MI]
    • Methylfluoro-isopropyl ester
    • (.+/-.)-Sarin
    • SCHEMBL50256
    • Fluoroisopropoxymethylphosphine
    • CHEMBL509554
    • DTXCID8022371
    • CHEBI:75873
    • DTXSID70897222
    • GB (CHEMICAL WARFARE AGENT)
    • BDBM50027343
    • propan-2-yl methylphosphonofluoridate
    • Isopropyl methylphosphonofluoridoate #
    • rac-isopropyl methylphosphonofluoridate
    • AKOS006273454
    • Methylfluorphosphorsaeureisopropyl ester
    • (RS)-isopropyl methylphosphonofluoridate
    • rac-propan-2-yl methylphosphonofluoridate
    • T144
    • NS00075366
    • NS00075518
    • PHOSPHINE OXIDE, FLUOROISOPROPOXYMETHYL
    • Fluoroisopropoxymethyl phospline phosphine oxide
    • Methylphosphonofluoridic acid 1-methyl-ethyl ester
    • Q187695

  • Applications

    Sarin (CAS 107-44-8) is a highly toxic organophosphorus nerve agent and has no legitimate industrial or commercial applications. As a Schedule 1 chemical weapon under international conventions, its manufacture, possession, transport, and use are strictly regulated, with any work limited to compliance, safety, and approved research under controlled conditions. Consequently, discussions of practical 'applications' are avoided, and information focuses on safety guidelines, detection, decontamination, and emergency response rather than legitimate industrial uses.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1225.84
    methanol 1902.62
    isopropanol 709.01
    water 457.51
    ethyl acetate 367.02
    n-propanol 749.26
    acetone 840.61
    n-butanol 514.57
    acetonitrile 696.51
    DMF 1402.06
    toluene 272.5
    isobutanol 389.62
    1,4-dioxane 708.24
    methyl acetate 431.81
    THF 1152.94
    2-butanone 477.83
    n-pentanol 310.31
    sec-butanol 514.89
    n-hexane 83.74
    ethylene glycol 673.77
    NMP 1167.84
    cyclohexane 103.54
    DMSO 1098.32
    n-butyl acetate 131.03
    n-octanol 182.4
    chloroform 713.12
    n-propyl acetate 169.23
    acetic acid 1211.47
    dichloromethane 712.4
    cyclohexanone 592.33
    propylene glycol 597.25
    isopropyl acetate 199.39
    DMAc 826.5
    2-ethoxyethanol 620.61
    isopentanol 283.46
    n-heptane 44.0
    ethyl formate 348.37
    1,2-dichloroethane 467.5
    n-hexanol 288.11
    2-methoxyethanol 1335.16
    isobutyl acetate 90.98
    tetrachloromethane 106.22
    n-pentyl acetate 138.65
    transcutol 779.34
    n-heptanol 134.17
    ethylbenzene 109.32
    MIBK 191.31
    2-propoxyethanol 558.42
    tert-butanol 607.11
    MTBE 289.8
    2-butoxyethanol 252.8
    propionic acid 557.93
    o-xylene 159.81
    formic acid 1048.78
    diethyl ether 448.2
    m-xylene 178.05
    p-xylene 115.8
    chlorobenzene 253.95
    dimethyl carbonate 184.21
    n-octane 21.53
    formamide 1146.15
    cyclopentanone 761.15
    2-pentanone 403.6
    anisole 235.08
    cyclopentyl methyl ether 476.59
    gamma-butyrolactone 876.87
    1-methoxy-2-propanol 831.29
    pyridine 557.25
    3-pentanone 303.94
    furfural 869.61
    n-dodecane 18.12
    diethylene glycol 607.69
    diisopropyl ether 107.99
    tert-amyl alcohol 404.7
    acetylacetone 439.39
    n-hexadecane 19.24
    acetophenone 206.37
    methyl propionate 354.31
    isopentyl acetate 109.49
    trichloroethylene 691.87
    n-nonanol 153.69
    cyclohexanol 493.71
    benzyl alcohol 244.06
    2-ethylhexanol 112.25
    isooctanol 87.84
    dipropyl ether 148.14
    1,2-dichlorobenzene 203.8
    ethyl lactate 145.43
    propylene carbonate 371.03
    n-methylformamide 965.58
    2-pentanol 339.02
    n-pentane 116.66
    1-propoxy-2-propanol 307.07
    1-methoxy-2-propyl acetate 188.44
    2-(2-methoxypropoxy) propanol 236.89
    mesitylene 112.19
    ε-caprolactone 506.95
    p-cymene 63.82
    epichlorohydrin 749.23
    1,1,1-trichloroethane 307.64
    2-aminoethanol 852.6
    morpholine-4-carbaldehyde 911.51
    sulfolane 887.19
    2,2,4-trimethylpentane 33.41
    2-methyltetrahydrofuran 657.34
    n-hexyl acetate 228.38
    isooctane 22.84
    2-(2-butoxyethoxy)ethanol 347.9
    sec-butyl acetate 111.37
    tert-butyl acetate 204.93
    decalin 37.18
    glycerin 820.88
    diglyme 445.36
    acrylic acid 584.16
    isopropyl myristate 92.7
    n-butyric acid 475.96
    acetyl acetate 241.11
    di(2-ethylhexyl) phthalate 94.81
    ethyl propionate 183.7
    nitromethane 1396.76
    1,2-diethoxyethane 200.4
    benzonitrile 244.21
    trioctyl phosphate 75.75
    1-bromopropane 300.08
    gamma-valerolactone 999.35
    n-decanol 112.64
    triethyl phosphate 74.3
    4-methyl-2-pentanol 150.05
    propionitrile 382.08
    vinylene carbonate 377.23
    1,1,2-trichlorotrifluoroethane 516.55
    DMS 176.16
    cumene 76.96
    2-octanol 114.03
    2-hexanone 195.07
    octyl acetate 127.33
    limonene 91.86
    1,2-dimethoxyethane 644.5
    ethyl orthosilicate 72.93
    tributyl phosphate 92.13
    diacetone alcohol 302.53
    N,N-dimethylaniline 173.73
    acrylonitrile 496.64
    aniline 379.19
    1,3-propanediol 732.0
    bromobenzene 215.2
    dibromomethane 485.04
    1,1,2,2-tetrachloroethane 497.58
    2-methyl-cyclohexyl acetate 112.52
    tetrabutyl urea 134.14
    diisobutyl methanol 71.53
    2-phenylethanol 190.91
    styrene 124.18
    dioctyl adipate 133.77
    dimethyl sulfate 319.18
    ethyl butyrate 119.69
    methyl lactate 281.74
    butyl lactate 138.18
    diethyl carbonate 80.69
    propanediol butyl ether 304.2
    triethyl orthoformate 90.61
    p-tert-butyltoluene 67.39
    methyl 4-tert-butylbenzoate 200.18
    morpholine 927.69
    tert-butylamine 390.73
    n-dodecanol 85.74
    dimethoxymethane 690.08
    ethylene carbonate 284.16
    cyrene 241.14
    2-ethoxyethyl acetate 187.11
    2-ethylhexyl acetate 90.36
    1,2,4-trichlorobenzene 237.96
    4-methylpyridine 547.77
    dibutyl ether 123.83
    2,6-dimethyl-4-heptanol 71.53
    DEF 450.06
    dimethyl isosorbide 350.66
    tetrachloroethylene 347.09
    eugenol 218.67
    triacetin 211.83
    span 80 242.04
    1,4-butanediol 291.22
    1,1-dichloroethane 423.07
    2-methyl-1-pentanol 197.47
    methyl formate 667.72
    2-methyl-1-butanol 311.45
    n-decane 28.84
    butyronitrile 341.95
    3,7-dimethyl-1-octanol 125.18
    1-chlorooctane 89.44
    1-chlorotetradecane 42.36
    n-nonane 29.84
    undecane 21.98
    tert-butylcyclohexane 34.42
    cyclooctane 38.08
    cyclopentanol 557.44
    tetrahydropyran 611.39
    tert-amyl methyl ether 250.99
    2,5,8-trioxanonane 361.22
    1-hexene 175.59
    2-isopropoxyethanol 319.07
    2,2,2-trifluoroethanol 466.94
    methyl butyrate 220.25

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction