Ribonic acid

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  • Identifiers

    CAS number
    17812-24-7

    Molecular formula
    C5H10O6

    SMILES
    C([C@H]([C@H]([C@H](C(=O)O)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 70.92%
    Sweet 37.3%
    Caramellic 33.27%
    Buttery 25.09%
    Milky 19.15%
    Sharp 18.86%
    Clean 18.44%
    Savory 18.27%
    Sour 17.68%
    Burnt 15.88%

     

    Flavor
    Odorless 74.61%
    Very mild 32.83%
    Sweet-like 29.84%
    Sweet 28.96%
    Bland 23.55%
    Mild 22.28%
    Caramellic 21.38%
    Yeast 20.86%
    Very slight 20.6%
    Sour 19.66%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -2.7

    pKa est.
    3.29 (weak acid)

    Molecular weight
    166.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    526°C

    Flash point

    • 226.68 ˚C est.

  • Synonyms

    • Ribonic acid
    • 17812-24-7
    • DTXSID801021863
    • RefChem:179378
    • GlyTouCan:G23711DK
    • CHEBI:33511
    • DTXCID501765656
    • G23711DK
    • D-ribonic acid
    • (2R,3R,4R)-2,3,4,5-tetrahydroxypentanoic acid
    • 642-98-8
    • Ribonate
    • Rel-(2R,3R,4R)-2,3,4,5-tetrahydroxypentanoic acid
    • D-(-)-Ribonic acid
    • starbld0007008
    • SCHEMBL416686
    • CHEBI:21077
    • AKOS006290789
    • HY-153995A
    • C01685
    • Q27109369
    • 99235101-DD2D-4AB2-9123-10463F65AA6F
    • 17812-24-7

  • Applications

    Ribonic acid (CAS 17812-24-7) is primarily used as a sugar-derived intermediate and a chiral building block in organic synthesis, enabling access to sugar-derived fine chemicals and intermediates for pharmaceutical and agrochemical manufacture. It also serves as a precursor for derivatives used in polymers and plastic materials. In cosmetics and personal care, it may function as an intermediate or functional ingredient in formulations, subject to local regulations. In cleaning and household products, it can be employed as a pH modifier or a precursor for functional additives, depending on formulation requirements and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.47
    methanol 27.29
    isopropanol 2.58
    water 611.9
    ethyl acetate 0.85
    n-propanol 2.42
    acetone 1.91
    n-butanol 1.65
    acetonitrile 1.18
    DMF 224.26
    toluene 0.33
    isobutanol 1.27
    1,4-dioxane 7.41
    methyl acetate 0.79
    THF 3.12
    2-butanone 1.15
    n-pentanol 1.07
    sec-butanol 1.96
    n-hexane 0.2
    ethylene glycol 146.93
    NMP 125.03
    cyclohexane 1.03
    DMSO 528.19
    n-butyl acetate 0.55
    n-octanol 1.12
    chloroform 0.26
    n-propyl acetate 0.38
    acetic acid 5.47
    dichloromethane 0.62
    cyclohexanone 2.88
    propylene glycol 42.05
    isopropyl acetate 0.67
    DMAc 101.15
    2-ethoxyethanol 16.38
    isopentanol 1.19
    n-heptane 1.17
    ethyl formate 0.85
    1,2-dichloroethane 1.01
    n-hexanol 1.61
    2-methoxyethanol 51.88
    isobutyl acetate 0.15
    tetrachloromethane 0.23
    n-pentyl acetate 0.46
    transcutol 11.08
    n-heptanol 1.63
    ethylbenzene 0.28
    MIBK 0.85
    2-propoxyethanol 10.36
    tert-butanol 2.95
    MTBE 0.91
    2-butoxyethanol 5.8
    propionic acid 3.23
    o-xylene 0.94
    formic acid 138.28
    diethyl ether 0.99
    m-xylene 0.58
    p-xylene 0.3
    chlorobenzene 0.13
    dimethyl carbonate 4.13
    n-octane 0.37
    formamide 112.79
    cyclopentanone 3.09
    2-pentanone 1.2
    anisole 0.68
    cyclopentyl methyl ether 2.23
    gamma-butyrolactone 4.78
    1-methoxy-2-propanol 26.26
    pyridine 1.5
    3-pentanone 1.48
    furfural 6.55
    n-dodecane 0.19
    diethylene glycol 39.9
    diisopropyl ether 0.54
    tert-amyl alcohol 2.73
    acetylacetone 2.61
    n-hexadecane 0.2
    acetophenone 1.21
    methyl propionate 2.55
    isopentyl acetate 0.41
    trichloroethylene 0.77
    n-nonanol 1.07
    cyclohexanol 3.15
    benzyl alcohol 1.67
    2-ethylhexanol 1.03
    isooctanol 1.11
    dipropyl ether 1.63
    1,2-dichlorobenzene 0.26
    ethyl lactate 2.69
    propylene carbonate 1.5
    n-methylformamide 40.57
    2-pentanol 1.34
    n-pentane 0.33
    1-propoxy-2-propanol 6.31
    1-methoxy-2-propyl acetate 2.51
    2-(2-methoxypropoxy) propanol 5.62
    mesitylene 0.7
    ε-caprolactone 2.77
    p-cymene 0.67
    epichlorohydrin 2.61
    1,1,1-trichloroethane 0.19
    2-aminoethanol 58.01
    morpholine-4-carbaldehyde 75.02
    sulfolane 42.04
    2,2,4-trimethylpentane 0.21
    2-methyltetrahydrofuran 1.56
    n-hexyl acetate 0.54
    isooctane 0.12
    2-(2-butoxyethoxy)ethanol 7.49
    sec-butyl acetate 0.27
    tert-butyl acetate 0.91
    decalin 0.29
    glycerin 172.29
    diglyme 13.38
    acrylic acid 6.96
    isopropyl myristate 0.33
    n-butyric acid 1.78
    acetyl acetate 0.69
    di(2-ethylhexyl) phthalate 0.64
    ethyl propionate 0.66
    nitromethane 9.83
    1,2-diethoxyethane 1.34
    benzonitrile 0.47
    trioctyl phosphate 0.7
    1-bromopropane 0.32
    gamma-valerolactone 12.34
    n-decanol 0.9
    triethyl phosphate 0.98
    4-methyl-2-pentanol 0.82
    propionitrile 0.65
    vinylene carbonate 1.47
    1,1,2-trichlorotrifluoroethane 16.95
    DMS 1.05
    cumene 0.31
    2-octanol 0.86
    2-hexanone 0.48
    octyl acetate 0.48
    limonene 1.19
    1,2-dimethoxyethane 8.43
    ethyl orthosilicate 0.97
    tributyl phosphate 0.47
    diacetone alcohol 4.9
    N,N-dimethylaniline 1.82
    acrylonitrile 1.55
    aniline 1.02
    1,3-propanediol 26.14
    bromobenzene 0.11
    dibromomethane 0.37
    1,1,2,2-tetrachloroethane 1.36
    2-methyl-cyclohexyl acetate 0.59
    tetrabutyl urea 1.64
    diisobutyl methanol 1.03
    2-phenylethanol 1.48
    styrene 0.22
    dioctyl adipate 0.6
    dimethyl sulfate 18.24
    ethyl butyrate 0.74
    methyl lactate 14.25
    butyl lactate 1.38
    diethyl carbonate 0.43
    propanediol butyl ether 6.97
    triethyl orthoformate 1.01
    p-tert-butyltoluene 0.75
    methyl 4-tert-butylbenzoate 2.78
    morpholine 11.27
    tert-butylamine 1.32
    n-dodecanol 0.77
    dimethoxymethane 19.36
    ethylene carbonate 1.19
    cyrene 15.63
    2-ethoxyethyl acetate 0.86
    2-ethylhexyl acetate 0.37
    1,2,4-trichlorobenzene 0.37
    4-methylpyridine 1.0
    dibutyl ether 0.53
    2,6-dimethyl-4-heptanol 1.03
    DEF 11.8
    dimethyl isosorbide 7.86
    tetrachloroethylene 1.35
    eugenol 3.47
    triacetin 1.3
    span 80 5.18
    1,4-butanediol 13.22
    1,1-dichloroethane 0.24
    2-methyl-1-pentanol 0.76
    methyl formate 11.55
    2-methyl-1-butanol 1.32
    n-decane 0.29
    butyronitrile 0.5
    3,7-dimethyl-1-octanol 0.69
    1-chlorooctane 0.38
    1-chlorotetradecane 0.23
    n-nonane 0.31
    undecane 0.22
    tert-butylcyclohexane 0.15
    cyclooctane 0.78
    cyclopentanol 3.16
    tetrahydropyran 1.7
    tert-amyl methyl ether 1.39
    2,5,8-trioxanonane 13.19
    1-hexene 0.2
    2-isopropoxyethanol 5.87
    2,2,2-trifluoroethanol 11.81
    methyl butyrate 0.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction