Riboflavin sodium phosphate

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  • Identifiers

    CAS number
    130-40-5

    Molecular formula
    C17H20N4NaO9P

    SMILES
    CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)(O)[O-])O)O)O.[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 83.57%
    Savory 20.88%
    Milky 19.5%
    Bitter 19.39%
    Cooked 16.11%
    Cooling 15.1%
    Clean 14.68%
    Fatty 14.15%
    Sweet 13.24%
    Grape 12.96%

     

    Flavor
    Odorless 64.13%
    Bitter 62.88%
    Bland 35.97%
    Mild 28.94%
    Very mild 26.87%
    Sweet-like 24.51%
    Yeast 19.68%
    Nitrile 18.94%
    Cedarleaf 18.36%
    Bread crust 18.24%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    6.31 (neutral)

    Molecular weight
    478.3 g/mol

    Flash point

    • 403.39 ˚C est.

  • Synonyms

    • 130-40-5
    • riboflavin sodium phosphate
    • RIBOFLAVIN PHOSPHATE SODIUM
    • Riboflavin-5-phosphate sodium
    • Photrexa
    • Riboflavin 5'-monophosphate sodium salt
    • Lactoflavin Phosphate Sodium Salt
    • Sodium (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl hydrogen phosphate
    • Flavin Mononucleotide Sodium Salt
    • Vitamin B2 Phosphate Sodium Salt
    • RIBOFLAVIN 5-PHOSPHATE SODIUM
    • Riboflavin (phosphate sodium)
    • Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1)
    • MFCD00065362
    • FMN-Na
    • Riboflavin sodium phosphate [JAN]
    • Riboflavin Phosphate Sodium Salt (~70%)
    • Riboflavina 5 fosfato de sodio
    • Riboflavin Phosphate Sodium Salt
    • Riboflavin sodium phosphate; riboflavin 5'-(sodium hydrogen phosphate)
    • UNII-957E53WV42
    • Infuvite (TN)
    • EINECS 204-988-6
    • EINECS 244-868-0
    • Riboflavin 5'-(sodium hydrogen phosphate)
    • SCHEMBL26122
    • 22251-85-0
    • Riboflavin 5'-(dihydrogen phosphate), sodium salt
    • Riboflavine-5-Phosphate Sodium
    • 7,8-Dimethyl-10-ribitylisoalloxazine Phosphate Sodium
    • orb1308952
    • orb3025120
    • Riboflavin sodium phosphate CRS
    • Riboflavine-5'-phosphate sodium
    • HY-B0964R
    • DTXSID80889330
    • MSK6912
    • HY-B0964
    • riboflavin-5'-phosphate sodium salt
    • sodium;[(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
    • Riboflavin sodium phosphate (JP18)
    • EBC-99034
    • Flavin Mononucleotide Monosodium Salt
    • CCG-269524
    • CS-4449
    • FR27725
    • NSC 759230
    • Riboflavin monophosphate monosodium salt
    • DA-57438
    • Riboflavin phosphate (sodium) (Standard)
    • R0023
    • R0249
    • RIBOFLAVIN SODIUM PHOSPHATE [WHO-DD]
    • D01622
    • FLAVIN MONONUCLEOTIDE MONOSODIUM SALT [MI]
    • Q27271760
    • Sodium 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-(hydroxyphosphinato)-D-ribitol
    • 130-40-5

  • Applications

    Riboflavin sodium phosphate, CAS 130-40-5, is the water-soluble sodium salt of riboflavin (vitamin B2). In practice it is used as a nutritional source of riboflavin in pharmaceutical formulations and dietary supplements; it serves as a vitamin B2 fortificant in foods and beverages across various processing sectors; it is also employed as a feed additive to supply riboflavin to poultry, swine, and aquaculture species. Additionally, this salt may be used as an ingredient in cosmetics/personal care formulations to deliver vitamin B2. Formulations and usage should comply with local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.82
    methanol 4.06
    isopropanol 0.78
    water 7.21
    ethyl acetate 0.1
    n-propanol 1.13
    acetone 1.01
    n-butanol 0.48
    acetonitrile 0.34
    DMF 14.59
    toluene 0.03
    isobutanol 0.35
    1,4-dioxane 0.74
    methyl acetate 0.33
    THF 2.16
    2-butanone 0.6
    n-pentanol 0.25
    sec-butanol 0.48
    n-hexane 0.01
    ethylene glycol 13.43
    NMP 28.95
    cyclohexane 0.03
    DMSO 43.79
    n-butyl acetate 0.16
    n-octanol 0.1
    chloroform 0.1
    n-propyl acetate 0.12
    acetic acid 11.43
    dichloromethane 0.16
    cyclohexanone 0.95
    propylene glycol 8.1
    isopropyl acetate 0.06
    DMAc 16.28
    2-ethoxyethanol 4.54
    isopentanol 0.22
    n-heptane 0.03
    ethyl formate 0.64
    1,2-dichloroethane 0.17
    n-hexanol 0.22
    2-methoxyethanol 16.2
    isobutyl acetate 0.04
    tetrachloromethane 0.06
    n-pentyl acetate 0.12
    transcutol 2.13
    n-heptanol 0.22
    ethylbenzene 0.02
    MIBK 0.1
    2-propoxyethanol 2.73
    tert-butanol 0.5
    MTBE 0.06
    2-butoxyethanol 1.58
    propionic acid 1.88
    o-xylene 0.04
    formic acid 57.48
    diethyl ether 0.13
    m-xylene 0.03
    p-xylene 0.03
    chlorobenzene 0.02
    dimethyl carbonate 0.68
    n-octane 0.01
    formamide 54.78
    cyclopentanone 2.31
    2-pentanone 0.26
    anisole 0.06
    cyclopentyl methyl ether 0.27
    gamma-butyrolactone 3.34
    1-methoxy-2-propanol 4.67
    pyridine 0.64
    3-pentanone 0.25
    furfural 4.17
    n-dodecane 0.01
    diethylene glycol 8.6
    diisopropyl ether 0.02
    tert-amyl alcohol 0.36
    acetylacetone 0.44
    n-hexadecane 0.01
    acetophenone 0.17
    methyl propionate 0.33
    isopentyl acetate 0.1
    trichloroethylene 0.2
    n-nonanol 0.12
    cyclohexanol 0.33
    benzyl alcohol 0.23
    2-ethylhexanol 0.09
    isooctanol 0.12
    dipropyl ether 0.16
    1,2-dichlorobenzene 0.03
    ethyl lactate 0.62
    propylene carbonate 0.84
    n-methylformamide 9.91
    2-pentanol 0.17
    n-pentane 0.02
    1-propoxy-2-propanol 1.19
    1-methoxy-2-propyl acetate 0.34
    2-(2-methoxypropoxy) propanol 1.14
    mesitylene 0.02
    ε-caprolactone 0.78
    p-cymene 0.03
    epichlorohydrin 1.26
    1,1,1-trichloroethane 0.04
    2-aminoethanol 9.79
    morpholine-4-carbaldehyde 10.51
    sulfolane 13.71
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 0.47
    n-hexyl acetate 0.09
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 1.7
    sec-butyl acetate 0.05
    tert-butyl acetate 0.08
    decalin 0.01
    glycerin 33.7
    diglyme 2.58
    acrylic acid 4.02
    isopropyl myristate 0.04
    n-butyric acid 0.81
    acetyl acetate 0.1
    di(2-ethylhexyl) phthalate 0.15
    ethyl propionate 0.11
    nitromethane 9.71
    1,2-diethoxyethane 0.18
    benzonitrile 0.1
    trioctyl phosphate 0.12
    1-bromopropane 0.06
    gamma-valerolactone 6.38
    n-decanol 0.09
    triethyl phosphate 0.2
    4-methyl-2-pentanol 0.06
    propionitrile 0.21
    vinylene carbonate 0.68
    1,1,2-trichlorotrifluoroethane 6.97
    DMS 0.18
    cumene 0.02
    2-octanol 0.09
    2-hexanone 0.18
    octyl acetate 0.09
    limonene 0.04
    1,2-dimethoxyethane 2.75
    ethyl orthosilicate 0.16
    tributyl phosphate 0.11
    diacetone alcohol 0.73
    N,N-dimethylaniline 0.09
    acrylonitrile 0.49
    aniline 0.18
    1,3-propanediol 6.53
    bromobenzene 0.01
    dibromomethane 0.09
    1,1,2,2-tetrachloroethane 0.25
    2-methyl-cyclohexyl acetate 0.13
    tetrabutyl urea 0.35
    diisobutyl methanol 0.05
    2-phenylethanol 0.22
    styrene 0.02
    dioctyl adipate 0.11
    dimethyl sulfate 2.39
    ethyl butyrate 0.15
    methyl lactate 2.41
    butyl lactate 0.51
    diethyl carbonate 0.13
    propanediol butyl ether 1.58
    triethyl orthoformate 0.2
    p-tert-butyltoluene 0.03
    methyl 4-tert-butylbenzoate 0.35
    morpholine 1.6
    tert-butylamine 0.12
    n-dodecanol 0.07
    dimethoxymethane 2.51
    ethylene carbonate 0.46
    cyrene 3.36
    2-ethoxyethyl acetate 0.24
    2-ethylhexyl acetate 0.08
    1,2,4-trichlorobenzene 0.06
    4-methylpyridine 0.23
    dibutyl ether 0.05
    2,6-dimethyl-4-heptanol 0.05
    DEF 0.89
    dimethyl isosorbide 1.78
    tetrachloroethylene 0.25
    eugenol 0.69
    triacetin 0.25
    span 80 0.83
    1,4-butanediol 2.09
    1,1-dichloroethane 0.05
    2-methyl-1-pentanol 0.13
    methyl formate 5.46
    2-methyl-1-butanol 0.26
    n-decane 0.01
    butyronitrile 0.14
    3,7-dimethyl-1-octanol 0.05
    1-chlorooctane 0.02
    1-chlorotetradecane 0.01
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.0
    cyclooctane 0.01
    cyclopentanol 0.96
    tetrahydropyran 0.32
    tert-amyl methyl ether 0.09
    2,5,8-trioxanonane 2.22
    1-hexene 0.03
    2-isopropoxyethanol 1.0
    2,2,2-trifluoroethanol 7.44
    methyl butyrate 0.22

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction