Racemethionine

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  • Identifiers

    CAS number
    59-51-8

    Molecular formula
    C5H11NO2S

    SMILES
    CSCCC(C(=O)O)N

  • Odor profile

    Fragrance
    Sulfurous 66.52%
    Meaty 66.22%
    Savory 52.04%
    Roasted 46.35%
    Onion 37.54%
    Cooked 36.59%
    Cheesy 34.4%
    Sweet 31.48%
    Cabbage 29.11%
    Alliaceous 28.17%

     

    Flavor
    Sulfurous 49.96%
    Sulfury 43.72%
    Odorless 32.95%
    Roasted 31.45%
    Onion 30.37%
    Mild 30.35%
    Cooked 30.25%
    Cabbage 26.47%
    Meaty 24.36%
    Tomato 22.51%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    -1.9

    pKa est.
    5.21 (weak acid)

    Molecular weight
    149.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 281 °C

    Boiling point

    • 300.00 to 301.00 °C. @ 760.00 mm Hg

    Flash point

    • 140.35 ˚C est.

    Solubility expt.

    • 32.7 mg/mL at 25 °C
    • Solubility in water, g/100ml at 20 °C: 4.8
    • Soluble in water; Insoluble in ether
    • Soluble (in ethanol)

  • Synonyms

    • DL-METHIONINE
    • 59-51-8
    • methionine
    • Racemethionine
    • Acimetion
    • Lobamine
    • Urimeth
    • Banthionine
    • Cynaron
    • Meonine
    • Mertionin
    • Metione
    • Pedameth
    • Dyprin
    • Neston
    • DL-Methioninum
    • (+-)-Methionine
    • 2-amino-4-(methylthio)butanoic acid
    • D,L-methionine
    • Methionine, DL-
    • DL-2-Amino-4-(methylthio)butanoic acid
    • FEMA No. 3301
    • 2-amino-4-methylsulfanylbutanoic acid
    • (+/-)-Methionine
    • Methionine dl-form
    • 2-amino-4-(methylsulfanyl)butanoic acid
    • NSC 9241
    • 2-Amino-4-(methylthio)butyric acid
    • MFCD00063096
    • Methilonin
    • Racemethionine [USAN]
    • CCRIS 3717
    • dl-methionin
    • DL-2-Amino-4-(methylthio)-butyric acid
    • alpha-Amino-gamma-methylmercaptobutyric acid
    • NSC-9241
    • EINECS 200-432-1
    • UNII-73JWT2K6T3
    • DL-2-Amino-4-(methylthio)butyric acid
    • 73JWT2K6T3
    • 26062-47-5
    • CHEBI:16811
    • alpha-Amino-gamma-(methylthio)butyric acid
    • AI3-18475
    • 2-amino-4-methylsulfanyl-butanoic acid
    • DL-Methionine (Racemethionine)
    • 7005-18-7
    • Racemethionine [USAN:USP:NF]
    • DTXSID9020821
    • (+/-)-2-Amino-4-(methylmercapto)butyric acid
    • 2-Amino-4-methylthiobutanoic acid
    • NSC22946
    • 2-Amino-4-(methylmercapto)butyric acid
    • NCGC00159431-02
    • DL-Methionine (JAN)
    • Racemethionine (USAN)
    • H-DL-Met-OH
    • .alpha.-Amino-.gamma.-methylmercaptobutyric acid
    • DL-METHIONINE [JAN]
    • (+/-)-Methionine-d4
    • Hmet
    • R-Methionine
    • Methionine, amorphous
    • Racemethionine (USAN:USP:NF)
    • RACEMETHIONINE (USP-RS)
    • RACEMETHIONINE [USP-RS]
    • Methionine DL-
    • Padameth
    • Petameth
    • Amurex
    • dl-Methionine; (2RS)-2-amino-4-(methylsulfanyl)butanoic acid
    • Metion
    • Methio-Form
    • Padameth (TN)
    • alpha-Amino-gamma-methylmercaptobutyric acid (VAN)
    • DL-Met
    • DL-2-Amino-4-methylthiobutanoic acid
    • Racemethionine, USAN
    • METHIONINE,L-
    • 2-amino-4-(methylthio)-butyric acid
    • (.+-.)-Methionine
    • (.+/-.)-Methionine
    • Met248
    • DL-Methionine (Standard)
    • DL-Methionine, >=99%
    • SCHEMBL4225
    • DL-METHIONINE [FCC]
    • WLN: QVYZ2S1 -L
    • DTXCID50821
    • D,L-METHIONINE [FHFI]
    • DL-METHIONINE [MART.]
    • CHEMBL274119
    • DL-METHIONINE [WHO-DD]
    • DL-METHIONINE [WHO-IP]
    • H3CSCH2CH2CH(NH2)COOH
    • L-Methionine, non animal origin
    • METHIONINE DL-FORM [MI]
    • BDBM86195
    • FEMA 3301
    • HY-N0325R
    • NSC9241
    • DL-CH3SCH2CH2CH(NH2)COOH
    • DL-Methionine, 99%, FCC, FG
    • CAS_6137
    • DL-METHIONINE [EP IMPURITY]
    • HY-N0325
    • NSC_6137
    • NSC45689
    • TDA70961
    • ZBA70526
    • Tox21_111663
    • BBL009323
    • CAS_84815
    • DL-METHIONINE [EP MONOGRAPH]
    • DL-Methionine, >=99.0% (NT)
    • NSC_84815
    • NSC118113
    • NSC522406
    • s9344
    • STK802463
    • 2-amino-4-(methylthio) butyric acid
    • AKOS000118924
    • AKOS016050523
    • DL-METHIONINUM [WHO-IP LATIN]
    • CCG-266195
    • DB13972
    • FM29234
    • NSC-118113

  • Applications

    DL-Methionine, CAS 59-51-8, is an essential amino acid widely used in animal nutrition, food technology, pharmaceuticals and cosmetics because it supplies valuable methyl and sulfur groups for metabolic processes; in animal feed, especially for poultry, swine and aquaculture species, DL-Methionine is added to balance dietary protein, promote growth, improve feed conversion, lower production costs and reduce nitrogen excretion into the environment; in the food industry it functions as a flavor enhancer, antioxidant and aroma precursor, helping stabilize the color and taste of processed foods; in medicine and pharmacy, DL-Methionine supports the treatment of liver disorders, paracetamol poisoning and urinary bladder stones thanks to its detoxifying and urine-acidifying properties, and also serves as a building block for peptide, vitamin and parenteral nutrition formulations; additionally, DL-Methionine is incorporated into skin and hair care products to nourish keratin, combat aging and protect the skin from oxidative damage, thereby extending its reach within the cosmetic sector.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.78
    methanol 1.89
    isopropanol 0.53
    water 34.5
    ethyl acetate 0.25
    n-propanol 0.48
    acetone 0.64
    n-butanol 0.4
    acetonitrile 0.21
    DMF 4.08
    toluene 0.14
    isobutanol 0.5
    1,4-dioxane 1.45
    methyl acetate 0.17
    THF 2.46
    2-butanone 0.25
    n-pentanol 0.65
    sec-butanol 0.37
    n-hexane 0.08
    ethylene glycol 11.7
    NMP 30.18
    cyclohexane 0.23
    DMSO 31.48
    n-butyl acetate 0.99
    n-octanol 0.84
    chloroform 0.14
    n-propyl acetate 0.47
    acetic acid 14.0
    dichloromethane 0.23
    cyclohexanone 3.78
    propylene glycol 5.45
    isopropyl acetate 0.44
    DMAc 6.62
    2-ethoxyethanol 5.07
    isopentanol 0.79
    n-heptane 0.24
    ethyl formate 0.56
    1,2-dichloroethane 0.23
    n-hexanol 1.54
    2-methoxyethanol 6.51
    isobutyl acetate 0.47
    tetrachloromethane 0.12
    n-pentyl acetate 0.98
    transcutol 12.79
    n-heptanol 1.67
    ethylbenzene 0.24
    MIBK 0.74
    2-propoxyethanol 6.73
    tert-butanol 1.55
    MTBE 0.23
    2-butoxyethanol 6.16
    propionic acid 2.28
    o-xylene 0.49
    formic acid 31.76
    diethyl ether 0.08
    m-xylene 0.39
    p-xylene 0.42
    chlorobenzene 0.21
    dimethyl carbonate 0.42
    n-octane 0.12
    formamide 16.84
    cyclopentanone 4.06
    2-pentanone 0.4
    anisole 0.48
    cyclopentyl methyl ether 0.98
    gamma-butyrolactone 5.7
    1-methoxy-2-propanol 4.08
    pyridine 0.73
    3-pentanone 0.27
    furfural 9.51
    n-dodecane 0.09
    diethylene glycol 16.5
    diisopropyl ether 0.19
    tert-amyl alcohol 1.18
    acetylacetone 2.09
    n-hexadecane 0.1
    acetophenone 1.59
    methyl propionate 0.29
    isopentyl acetate 1.45
    trichloroethylene 0.45
    n-nonanol 0.93
    cyclohexanol 1.62
    benzyl alcohol 1.64
    2-ethylhexanol 1.38
    isooctanol 1.68
    dipropyl ether 0.52
    1,2-dichlorobenzene 0.5
    ethyl lactate 1.92
    propylene carbonate 3.76
    n-methylformamide 2.16
    2-pentanol 0.32
    n-pentane 0.04
    1-propoxy-2-propanol 4.86
    1-methoxy-2-propyl acetate 2.74
    2-(2-methoxypropoxy) propanol 7.42
    mesitylene 0.58
    ε-caprolactone 4.14
    p-cymene 0.83
    epichlorohydrin 1.58
    1,1,1-trichloroethane 0.17
    2-aminoethanol 7.86
    morpholine-4-carbaldehyde 18.14
    sulfolane 36.36
    2,2,4-trimethylpentane 0.08
    2-methyltetrahydrofuran 1.11
    n-hexyl acetate 1.16
    isooctane 0.09
    2-(2-butoxyethoxy)ethanol 9.51
    sec-butyl acetate 0.41
    tert-butyl acetate 1.14
    decalin 0.22
    glycerin 22.31
    diglyme 11.39
    acrylic acid 4.84
    isopropyl myristate 0.75
    n-butyric acid 2.38
    acetyl acetate 0.73
    di(2-ethylhexyl) phthalate 2.56
    ethyl propionate 0.38
    nitromethane 4.8
    1,2-diethoxyethane 1.01
    benzonitrile 0.86
    trioctyl phosphate 1.85
    1-bromopropane 0.07
    gamma-valerolactone 12.28
    n-decanol 0.78
    triethyl phosphate 1.48
    4-methyl-2-pentanol 0.62
    propionitrile 0.14
    vinylene carbonate 2.76
    1,1,2-trichlorotrifluoroethane 9.8
    DMS 1.32
    cumene 0.43
    2-octanol 0.86
    2-hexanone 0.52
    octyl acetate 1.01
    limonene 1.0
    1,2-dimethoxyethane 2.59
    ethyl orthosilicate 1.43
    tributyl phosphate 1.55
    diacetone alcohol 5.41
    N,N-dimethylaniline 1.04
    acrylonitrile 0.38
    aniline 0.48
    1,3-propanediol 5.92
    bromobenzene 0.18
    dibromomethane 0.15
    1,1,2,2-tetrachloroethane 0.58
    2-methyl-cyclohexyl acetate 2.66
    tetrabutyl urea 2.93
    diisobutyl methanol 1.32
    2-phenylethanol 2.37
    styrene 0.17
    dioctyl adipate 1.72
    dimethyl sulfate 2.55
    ethyl butyrate 0.99
    methyl lactate 2.73
    butyl lactate 3.28
    diethyl carbonate 0.76
    propanediol butyl ether 7.82
    triethyl orthoformate 1.37
    p-tert-butyltoluene 0.86
    methyl 4-tert-butylbenzoate 5.15
    morpholine 1.67
    tert-butylamine 0.58
    n-dodecanol 0.65
    dimethoxymethane 1.04
    ethylene carbonate 1.93
    cyrene 18.56
    2-ethoxyethyl acetate 1.61
    2-ethylhexyl acetate 1.06
    1,2,4-trichlorobenzene 0.76
    4-methylpyridine 0.51
    dibutyl ether 0.37
    2,6-dimethyl-4-heptanol 1.32
    DEF 1.23
    dimethyl isosorbide 15.48
    tetrachloroethylene 0.67
    eugenol 6.49
    triacetin 3.12
    span 80 9.19
    1,4-butanediol 4.13
    1,1-dichloroethane 0.08
    2-methyl-1-pentanol 0.97
    methyl formate 1.47
    2-methyl-1-butanol 0.56
    n-decane 0.11
    butyronitrile 0.19
    3,7-dimethyl-1-octanol 1.09
    1-chlorooctane 0.25
    1-chlorotetradecane 0.17
    n-nonane 0.1
    undecane 0.1
    tert-butylcyclohexane 0.16
    cyclooctane 0.17
    cyclopentanol 2.47
    tetrahydropyran 0.48
    tert-amyl methyl ether 0.32
    2,5,8-trioxanonane 13.16
    1-hexene 0.11
    2-isopropoxyethanol 3.32
    2,2,2-trifluoroethanol 5.87
    methyl butyrate 0.67

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction