(R)-2-Methylcyclohexan-1-one

Overview IFRA Request a quote

  • Identifiers

    CAS number
    22554-29-6

    Molecular formula
    C7H12O

    SMILES
    C[C@@H]1CCCCC1=O

    Safety labels

  • Odor profile

    Fragrance
    Mint 76.21%
    Ketonic 60.66%
    Camphoreous 55.29%
    Herbal 55.23%
    Solvent 41.11%
    Musty 39.33%
    Cooling 37.85%
    Woody 36.74%
    Tobacco 34.51%
    Earthy 33.83%

     

    Flavor
    Minty 59.84%
    Camphor 27.84%
    Fruity 24.81%
    Medicinal 23.4%
    Mint 23.38%
    Camphoraceous 21.06%
    Thujone 20.48%
    Cistus 20.46%
    Basil 19.89%
    Herbal 19.76%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.5

    pKa est.
    8.56 (weak base)

    Molecular weight
    112.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    169°C

    Flash point

    • 42.88 ˚C est.

  • Synonyms

    • (R)-2-Methylcyclohexan-1-one
    • (3R)-Methylcyclohexanon
    • 22554-29-6
    • SCHEMBL774064
    • LFSAPCRASZRSKS-ZCFIWIBFSA-N
    • 22554-29-6

  • Applications

    (R)-2-Methylcyclohexan-1-one is primarily used as a chiral building block and intermediate in organic synthesis. For this compound, in industrial contexts it is often employed as a precursor to more complex enantioenriched compounds, supporting the development of fragrance and specialty chemical products. In perfumery and cosmetics, (R)-2-Methylcyclohexan-1-one can function as a fragrance ingredient or fragrance intermediate. In household product formulations, it may contribute scent. As a precursor for asymmetric synthesis, (R)-2-Methylcyclohexan-1-one may serve as a starting material to access other enantiomerically enriched compounds for pharmaceutical research, subject to formulation constraints and regulatory limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1497.49
    methanol 1871.81
    isopropanol 859.7
    water 4.11
    ethyl acetate 938.06
    n-propanol 929.47
    acetone 966.87
    n-butanol 803.7
    acetonitrile 1449.43
    DMF 697.75
    toluene 404.39
    isobutanol 582.52
    1,4-dioxane 1484.05
    methyl acetate 787.83
    THF 1459.29
    2-butanone 750.47
    n-pentanol 602.08
    sec-butanol 576.52
    n-hexane 118.57
    ethylene glycol 158.95
    NMP 613.49
    cyclohexane 120.31
    DMSO 771.56
    n-butyl acetate 972.87
    n-octanol 298.27
    chloroform 3680.89
    n-propyl acetate 627.26
    acetic acid 1306.27
    dichloromethane 2654.96
    cyclohexanone 1035.52
    propylene glycol 190.48
    isopropyl acetate 516.95
    DMAc 429.55
    2-ethoxyethanol 613.66
    isopentanol 677.92
    n-heptane 74.26
    ethyl formate 675.94
    1,2-dichloroethane 1199.17
    n-hexanol 675.02
    2-methoxyethanol 913.85
    isobutyl acetate 373.14
    tetrachloromethane 572.54
    n-pentyl acetate 556.64
    transcutol 3411.98
    n-heptanol 314.58
    ethylbenzene 205.08
    MIBK 410.21
    2-propoxyethanol 851.45
    tert-butanol 803.63
    MTBE 653.32
    2-butoxyethanol 543.16
    propionic acid 789.94
    o-xylene 222.47
    formic acid 465.18
    diethyl ether 821.3
    m-xylene 246.74
    p-xylene 284.23
    chlorobenzene 796.99
    dimethyl carbonate 147.5
    n-octane 31.9
    formamide 559.06
    cyclopentanone 1035.54
    2-pentanone 611.15
    anisole 460.25
    cyclopentyl methyl ether 573.6
    gamma-butyrolactone 1237.24
    1-methoxy-2-propanol 603.96
    pyridine 1476.33
    3-pentanone 385.9
    furfural 1294.91
    n-dodecane 23.1
    diethylene glycol 512.21
    diisopropyl ether 228.2
    tert-amyl alcohol 524.55
    acetylacetone 651.85
    n-hexadecane 26.58
    acetophenone 397.32
    methyl propionate 472.88
    isopentyl acetate 728.26
    trichloroethylene 2443.33
    n-nonanol 255.26
    cyclohexanol 515.17
    benzyl alcohol 417.63
    2-ethylhexanol 377.19
    isooctanol 258.74
    dipropyl ether 423.71
    1,2-dichlorobenzene 663.72
    ethyl lactate 190.47
    propylene carbonate 738.91
    n-methylformamide 719.27
    2-pentanol 462.57
    n-pentane 97.47
    1-propoxy-2-propanol 640.57
    1-methoxy-2-propyl acetate 571.78
    2-(2-methoxypropoxy) propanol 466.41
    mesitylene 159.86
    ε-caprolactone 977.4
    p-cymene 154.68
    epichlorohydrin 1352.34
    1,1,1-trichloroethane 1329.34
    2-aminoethanol 410.08
    morpholine-4-carbaldehyde 941.88
    sulfolane 924.99
    2,2,4-trimethylpentane 51.75
    2-methyltetrahydrofuran 1004.86
    n-hexyl acetate 653.14
    isooctane 51.1
    2-(2-butoxyethoxy)ethanol 752.28
    sec-butyl acetate 372.73
    tert-butyl acetate 477.95
    decalin 62.87
    glycerin 250.3
    diglyme 1280.27
    acrylic acid 630.78
    isopropyl myristate 196.09
    n-butyric acid 1239.65
    acetyl acetate 549.12
    di(2-ethylhexyl) phthalate 188.7
    ethyl propionate 396.06
    nitromethane 1560.19
    1,2-diethoxyethane 1138.63
    benzonitrile 940.25
    trioctyl phosphate 127.54
    1-bromopropane 756.79
    gamma-valerolactone 1381.08
    n-decanol 170.92
    triethyl phosphate 165.72
    4-methyl-2-pentanol 280.41
    propionitrile 944.96
    vinylene carbonate 788.18
    1,1,2-trichlorotrifluoroethane 810.96
    DMS 374.89
    cumene 153.26
    2-octanol 216.62
    2-hexanone 591.78
    octyl acetate 250.48
    limonene 209.91
    1,2-dimethoxyethane 976.8
    ethyl orthosilicate 180.11
    tributyl phosphate 194.38
    diacetone alcohol 432.72
    N,N-dimethylaniline 253.7
    acrylonitrile 1155.41
    aniline 590.59
    1,3-propanediol 599.67
    bromobenzene 795.69
    dibromomethane 1706.23
    1,1,2,2-tetrachloroethane 1612.0
    2-methyl-cyclohexyl acetate 324.21
    tetrabutyl urea 195.14
    diisobutyl methanol 209.74
    2-phenylethanol 487.47
    styrene 314.2
    dioctyl adipate 264.09
    dimethyl sulfate 188.81
    ethyl butyrate 509.97
    methyl lactate 185.39
    butyl lactate 353.97
    diethyl carbonate 300.1
    propanediol butyl ether 469.83
    triethyl orthoformate 318.87
    p-tert-butyltoluene 139.56
    methyl 4-tert-butylbenzoate 312.69
    morpholine 1479.76
    tert-butylamine 570.65
    n-dodecanol 119.42
    dimethoxymethane 449.54
    ethylene carbonate 641.28
    cyrene 274.16
    2-ethoxyethyl acetate 707.18
    2-ethylhexyl acetate 536.6
    1,2,4-trichlorobenzene 702.63
    4-methylpyridine 1222.03
    dibutyl ether 452.5
    2,6-dimethyl-4-heptanol 209.74
    DEF 554.71
    dimethyl isosorbide 645.35
    tetrachloroethylene 1220.88
    eugenol 356.22
    triacetin 471.04
    span 80 408.46
    1,4-butanediol 240.06
    1,1-dichloroethane 1493.72
    2-methyl-1-pentanol 498.9
    methyl formate 427.6
    2-methyl-1-butanol 542.98
    n-decane 44.85
    butyronitrile 1026.79
    3,7-dimethyl-1-octanol 320.55
    1-chlorooctane 198.05
    1-chlorotetradecane 66.9
    n-nonane 45.16
    undecane 30.69
    tert-butylcyclohexane 66.25
    cyclooctane 39.32
    cyclopentanol 554.59
    tetrahydropyran 1162.88
    tert-amyl methyl ether 372.07
    2,5,8-trioxanonane 738.27
    1-hexene 394.7
    2-isopropoxyethanol 451.99
    2,2,2-trifluoroethanol 321.11
    methyl butyrate 577.87

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction