Quizalofop

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  • Identifiers

    CAS number
    76578-12-6

    Molecular formula
    C17H13ClN2O4

    SMILES
    CC(C(=O)O)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl

    Safety labels

  • Odor profile

    Fragrance
    Odorless 41.97%
    Fruity 36.07%
    Roasted 27.45%
    Grape 27.01%
    Cooked 25.87%
    Savory 24.89%
    Milky 24.6%
    Meaty 23.47%
    Vanilla 23.4%
    Burnt 22.58%

     

    Flavor
    Bitter 72.96%
    Odorless 47.82%
    Bland 33.48%
    Mild 27.6%
    Very mild 23.58%
    Sweet-like 22.86%
    Parsley 19.48%
    Orange flower 19.45%
    Bread crust 19.38%
    Nitrile 19.31%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    3.6

    pKa est.
    6.83 (neutral)

    Molecular weight
    344.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    465°C

    Flash point

    • 245.13 ˚C est.

  • Synonyms

    • Quizalofop
    • 76578-12-6
    • Xylafop
    • Propanoic acid, 2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)-
    • DTXSID60273935
    • 137F325077
    • (RS)-2-(4-(6-Chloroquinoxalin-2-yloxy)phenoxy)propionic acid
    • (+-)-2-(4-(6-Chloro-2-quinoxalinyloxy)phenoxy)propanoic acid
    • Propanoic acid, 2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]-
    • RefChem:872085
    • CHEBI:81943
    • DTXCID70196424
    • 616-350-8
    • Quizalofop (free acid)
    • 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoic acid
    • 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid
    • Quizalofop (free acid) 10 microg/mL in Acetonitrile
    • Quizalofop [BSI:ISO]
    • CCRIS 9407
    • as sur-
    • UNII-137F325077
    • QUIZALOFOP [ISO]
    • CHEMBL51789
    • SCHEMBL111413
    • orb1306801
    • 2-[4-(6-chloro-2-quinoxalyloxy)phenoxy]propionic acid
    • CHEBI:137509
    • MSK22086
    • Propaquizafop acid (CGA 287422)
    • AKOS015960672
    • TS-08086
    • DB-056086
    • HY-123307
    • CS-0082447
    • NS00098682
    • C18763
    • D85430
    • Q2123552
    • 2-[4-(6-chloro-2-quinoxalinyloxy)phenoxy]propionic acid
    • 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propionic acid
    • 76578-12-6

  • Applications

    Quizalofop (CAS 76578-12-6) is primarily used as a selective post-emergence herbicide in agriculture, delivering grass weed control in crops such as rice, soybeans, canola, and other cereals by inhibiting acetyl-CoA carboxylase. It is formulated into crop-protection products (emulsifiable concentrates, suspension concentrates, and granules) for field application. It is commonly deployed as part of integrated weed management programs to protect yields and crop quality. In industrial and research settings, it is used in formulation development, field trials, and performance assessments of herbicidal activity and crop selectivity.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 28.17
    methanol 22.67
    isopropanol 29.26
    water 0.14
    ethyl acetate 25.34
    n-propanol 38.55
    acetone 82.07
    n-butanol 31.03
    acetonitrile 48.61
    DMF 97.56
    toluene 5.95
    isobutanol 24.34
    1,4-dioxane 116.78
    methyl acetate 46.57
    THF 323.39
    2-butanone 73.58
    n-pentanol 30.83
    sec-butanol 37.55
    n-hexane 1.26
    ethylene glycol 13.25
    NMP 30.28
    cyclohexane 1.19
    DMSO 211.23
    n-butyl acetate 11.45
    n-octanol 8.0
    chloroform 18.41
    n-propyl acetate 19.82
    acetic acid 36.03
    dichloromethane 38.96
    cyclohexanone 59.52
    propylene glycol 10.16
    isopropyl acetate 13.67
    DMAc 162.21
    2-ethoxyethanol 93.9
    isopentanol 22.04
    n-heptane 2.11
    ethyl formate 22.18
    1,2-dichloroethane 32.66
    n-hexanol 13.43
    2-methoxyethanol 109.34
    isobutyl acetate 7.99
    tetrachloromethane 1.19
    n-pentyl acetate 13.14
    transcutol 120.69
    n-heptanol 9.87
    ethylbenzene 5.38
    MIBK 14.27
    2-propoxyethanol 45.15
    tert-butanol 22.98
    MTBE 23.28
    2-butoxyethanol 28.2
    propionic acid 21.52
    o-xylene 4.73
    formic acid 23.94
    diethyl ether 33.57
    m-xylene 3.23
    p-xylene 7.72
    chlorobenzene 6.41
    dimethyl carbonate 20.46
    n-octane 1.25
    formamide 58.02
    cyclopentanone 75.66
    2-pentanone 35.41
    anisole 18.65
    cyclopentyl methyl ether 37.99
    gamma-butyrolactone 70.34
    1-methoxy-2-propanol 54.78
    pyridine 58.03
    3-pentanone 31.21
    furfural 45.23
    n-dodecane 1.06
    diethylene glycol 41.23
    diisopropyl ether 4.97
    tert-amyl alcohol 26.88
    acetylacetone 34.56
    n-hexadecane 1.19
    acetophenone 17.83
    methyl propionate 31.18
    isopentyl acetate 10.56
    trichloroethylene 36.38
    n-nonanol 9.38
    cyclohexanol 29.12
    benzyl alcohol 20.74
    2-ethylhexanol 8.43
    isooctanol 7.98
    dipropyl ether 21.13
    1,2-dichlorobenzene 5.58
    ethyl lactate 12.57
    propylene carbonate 17.79
    n-methylformamide 50.94
    2-pentanol 18.45
    n-pentane 0.8
    1-propoxy-2-propanol 26.95
    1-methoxy-2-propyl acetate 18.72
    2-(2-methoxypropoxy) propanol 26.17
    mesitylene 1.89
    ε-caprolactone 40.07
    p-cymene 3.33
    epichlorohydrin 127.01
    1,1,1-trichloroethane 7.69
    2-aminoethanol 20.96
    morpholine-4-carbaldehyde 74.9
    sulfolane 51.06
    2,2,4-trimethylpentane 0.58
    2-methyltetrahydrofuran 92.31
    n-hexyl acetate 13.26
    isooctane 0.23
    2-(2-butoxyethoxy)ethanol 39.56
    sec-butyl acetate 11.33
    tert-butyl acetate 11.38
    decalin 0.92
    glycerin 20.04
    diglyme 83.83
    acrylic acid 18.32
    isopropyl myristate 7.74
    n-butyric acid 22.78
    acetyl acetate 12.08
    di(2-ethylhexyl) phthalate 7.47
    ethyl propionate 18.73
    nitromethane 95.14
    1,2-diethoxyethane 49.51
    benzonitrile 15.97
    trioctyl phosphate 5.32
    1-bromopropane 16.89
    gamma-valerolactone 97.19
    n-decanol 8.2
    triethyl phosphate 9.19
    4-methyl-2-pentanol 7.23
    propionitrile 36.26
    vinylene carbonate 16.8
    1,1,2-trichlorotrifluoroethane 37.6
    DMS 14.16
    cumene 3.45
    2-octanol 7.53
    2-hexanone 30.41
    octyl acetate 10.34
    limonene 4.72
    1,2-dimethoxyethane 143.02
    ethyl orthosilicate 9.99
    tributyl phosphate 6.99
    diacetone alcohol 21.35
    N,N-dimethylaniline 13.01
    acrylonitrile 42.89
    aniline 17.26
    1,3-propanediol 36.78
    bromobenzene 5.02
    dibromomethane 19.56
    1,1,2,2-tetrachloroethane 30.87
    2-methyl-cyclohexyl acetate 10.59
    tetrabutyl urea 13.85
    diisobutyl methanol 5.26
    2-phenylethanol 13.67
    styrene 6.32
    dioctyl adipate 12.17
    dimethyl sulfate 23.94
    ethyl butyrate 14.77
    methyl lactate 18.31
    butyl lactate 11.41
    diethyl carbonate 11.17
    propanediol butyl ether 17.94
    triethyl orthoformate 15.43
    p-tert-butyltoluene 2.77
    methyl 4-tert-butylbenzoate 14.7
    morpholine 142.29
    tert-butylamine 9.58
    n-dodecanol 6.98
    dimethoxymethane 96.91
    ethylene carbonate 17.3
    cyrene 24.15
    2-ethoxyethyl acetate 24.84
    2-ethylhexyl acetate 8.48
    1,2,4-trichlorobenzene 7.7
    4-methylpyridine 31.93
    dibutyl ether 18.26
    2,6-dimethyl-4-heptanol 5.26
    DEF 47.16
    dimethyl isosorbide 36.9
    tetrachloroethylene 17.19
    eugenol 17.77
    triacetin 16.22
    span 80 16.3
    1,4-butanediol 23.52
    1,1-dichloroethane 16.08
    2-methyl-1-pentanol 22.65
    methyl formate 40.25
    2-methyl-1-butanol 26.29
    n-decane 1.7
    butyronitrile 29.48
    3,7-dimethyl-1-octanol 7.0
    1-chlorooctane 4.94
    1-chlorotetradecane 2.58
    n-nonane 1.43
    undecane 1.32
    tert-butylcyclohexane 0.58
    cyclooctane 0.41
    cyclopentanol 40.34
    tetrahydropyran 92.86
    tert-amyl methyl ether 22.27
    2,5,8-trioxanonane 59.71
    1-hexene 7.92
    2-isopropoxyethanol 45.92
    2,2,2-trifluoroethanol 14.46
    methyl butyrate 25.32

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction