Quinoline Yellow

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  • Identifiers

    CAS number
    8003-22-3

    Molecular formula
    C18H11NO2

    SMILES
    C1=CC=C2C(=C1)C=CC(=N2)C3C(=O)C4=CC=CC=C4C3=O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 41.93%
    Floral 36.11%
    Sweet 33.27%
    Bitter 32.41%
    Phenolic 29.66%
    Balsamic 29.05%
    Honey 28.64%
    Neroli 28.04%
    Coumarinic 27.94%
    Grape 25.96%

     

    Flavor
    Bitter 95.02%
    Odorless 21.3%
    Nitrile 18.82%
    Lovage 18.6%
    Very strong 18.33%
    Indole 18.15%
    Cedarleaf 18.13%
    Moth ball 17.67%
    Sweet-like 17.5%
    Naphthelene 17.42%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    6.03 (neutral)

    Molecular weight
    273.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    521°C

    Melting point expt.

    • 320 °F (Sublimes) (NTP, 1992)
    • 241 °C

    Flash point

    • 210.22 ˚C est.

    Solubility expt.

    • less than 1 mg/mL at 66 °F (NTP, 1992)
    • In water, 0.169 mg/L at 25 °C
    • In ethylene glycol monomethyl ether, 3 mg/mL; ethanol, 0.3 mg/mL
    • Soluble in acetone, benzene, toluene and xylene; slightly soluble in ethyl acetate, linseed oil, mineral oil, paraffin wax and stearic acid

  • Synonyms

    • Quinoline Yellow
    • 2-(quinolin-2-yl)-1H-indene-1,3(2H)-dione
    • CHEBI:53700
    • D&C Yellow No 10
    • RefChem:581451
    • D.C. Yellow No. 10
    • Colour Index No. 47005
    • 8003-22-3
    • Quinophthalone
    • Solvent yellow 33
    • 83-08-9
    • 11641 Yellow
    • Quinoline Yellow 2SF
    • Erio Chinoline Yellow 4G
    • 2-quinolin-2-ylindene-1,3-dione
    • 2-(2-Quinolyl)-1,3-indandione
    • D&C Yellow No. 11
    • 2-(2-Quinolyl)-1,3-indanedione
    • 2-(2-Quinolyl)-1H-indene-1,3(2H)-dione
    • C.I. SOLVENT YELLOW 33
    • D and C Yellow No. 11
    • D&C Yellow No 11
    • D & C Yellow 11
    • D and C Yellow 11
    • MFCD00011593
    • NSC 18950
    • 1H-Indene-1,3(2H)-dione, 2-(2-quinolinyl)-
    • Quinoline Yellow SS
    • Yellow 11
    • 1H-Indene-1, 2-(2-quinolinyl)-
    • D & C Yellow no. 11
    • 2-(2-Quinolinyl)-1H-indene-1,3(2H)-dione
    • Chinophthalon
    • CI 47000
    • QuinolineYellow
    • C.I. 47000
    • Amarelo Quinolina
    • EINECS 201-453-9
    • Quinophthalone (VAN)
    • DSSTox_CID_4906
    • Epitope ID:116214
    • DSSTox_RID_77574
    • Quinoline Yellow, 95.0%
    • DC YELLOW NO. 11
    • DSSTox_GSID_24906
    • SCHEMBL42716
    • MLS000037978
    • 2-(quinolin-2-yl)-2,3-dihydro-1H-indene-1,3-dione
    • orb2565394
    • orb2940600
    • CHEMBL1486465
    • SCHEMBL29350835
    • BDBM32227
    • cid_5355280
    • DTXSID00873130
    • MSK5877
    • NSC3047
    • NSC7503
    • 44F3HYL954
    • HMS2417K18
    • KI204
    • 2-(2-quinolyl)indane-1,3-dione
    • BB_SC-05451
    • HY-D0290
    • NSC-3047
    • NSC-7503
    • NSC18950
    • 2-(2-quinolyl)indane-1,3-quinone
    • Quinoline Yellow (C.I. 47000)
    • Tox21_202504
    • BBL027785
    • NSC-18950
    • STK367449
    • Quinoline Yellow, Dye content 95 %
    • AKOS000282972
    • Solvent Yellow 33 / Quinoline Yellow
    • CCG-103550
    • EBC-611434
    • NCGC00020851-01
    • NCGC00020851-02
    • NCGC00020851-03
    • NCGC00020851-04
    • NCGC00020851-05
    • NCGC00020851-06
    • NCGC00020851-07
    • NCGC00020851-08
    • NCGC00020851-09
    • NCGC00020851-10
    • NCGC00021766-02
    • NCGC00021766-03
    • NCGC00021766-04
    • NCGC00021766-05
    • NCGC00260053-01
    • AS-13999
    • Quinoline Yellow 2SF, analytical standard
    • SMR000035456
    • SY349355
    • CAS-8003-22-3
    • CS-0010202
    • NS00013519
    • ST50308384
    • 2-(1H-quinolin-2-ylidene)indene-1,3-dione
    • 2-(1H-quinolin-2-ylidene)indane-1,3-quinone
    • F87556
    • AE-641/14575007
    • SR-01000002715
    • Q7272330
    • SR-01000002715-2
    • 2-(2-quinolyl)-2-hydrocyclopenta[1,2-a]benzene-1,3-dione
    • 83-08-9

  • Applications

    Quinoline Yellow (CAS 8003-22-3) is a synthetic dye used as a colorant across several industries. In food processing, it serves as a permitted color additive (commonly referenced as E104 in regions where allowed) to impart yellow hues in confectionery, beverages, dairy products, baked goods, and preserved foods. In cosmetics and personal care, it is used as a colorant in certain markets for products such as lipsticks, creams, and hair care products, subject to local regulations. In coatings and inks, it is employed to provide yellow coloration in decorative coatings and packaging inks. In plastics and polymers, it can be added as a colorant for clear polymers and thermoplastics, typically during extrusion or molding.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.75
    methanol 0.82
    isopropanol 0.51
    water 0.0
    ethyl acetate 4.2
    n-propanol 0.81
    acetone 7.33
    n-butanol 0.85
    acetonitrile 4.06
    DMF 28.12
    toluene 4.2
    isobutanol 0.81
    1,4-dioxane 18.09
    methyl acetate 8.06
    THF 41.15
    2-butanone 8.88
    n-pentanol 1.25
    sec-butanol 0.67
    n-hexane 0.05
    ethylene glycol 0.91
    NMP 33.41
    cyclohexane 0.08
    DMSO 23.99
    n-butyl acetate 7.06
    n-octanol 1.09
    chloroform 10.66
    n-propyl acetate 6.66
    acetic acid 5.8
    dichloromethane 18.33
    cyclohexanone 19.23
    propylene glycol 0.66
    isopropyl acetate 4.91
    DMAc 47.61
    2-ethoxyethanol 5.76
    isopentanol 1.58
    n-heptane 0.12
    ethyl formate 3.84
    1,2-dichloroethane 18.36
    n-hexanol 1.77
    2-methoxyethanol 8.34
    isobutyl acetate 6.08
    tetrachloromethane 0.69
    n-pentyl acetate 5.23
    transcutol 39.84
    n-heptanol 1.61
    ethylbenzene 3.09
    MIBK 6.08
    2-propoxyethanol 9.79
    tert-butanol 1.14
    MTBE 1.45
    2-butoxyethanol 6.88
    propionic acid 3.18
    o-xylene 2.98
    formic acid 2.67
    diethyl ether 1.7
    m-xylene 2.81
    p-xylene 4.7
    chlorobenzene 7.24
    dimethyl carbonate 9.06
    n-octane 0.08
    formamide 7.16
    cyclopentanone 30.78
    2-pentanone 5.58
    anisole 8.61
    cyclopentyl methyl ether 7.77
    gamma-butyrolactone 34.99
    1-methoxy-2-propanol 5.99
    pyridine 24.57
    3-pentanone 5.5
    furfural 35.2
    n-dodecane 0.15
    diethylene glycol 9.62
    diisopropyl ether 1.0
    tert-amyl alcohol 1.21
    acetylacetone 15.94
    n-hexadecane 0.19
    acetophenone 13.2
    methyl propionate 5.63
    isopentyl acetate 9.09
    trichloroethylene 40.31
    n-nonanol 1.53
    cyclohexanol 1.86
    benzyl alcohol 6.84
    2-ethylhexanol 2.47
    isooctanol 1.99
    dipropyl ether 3.41
    1,2-dichlorobenzene 8.87
    ethyl lactate 5.45
    propylene carbonate 14.72
    n-methylformamide 6.77
    2-pentanol 0.68
    n-pentane 0.03
    1-propoxy-2-propanol 6.93
    1-methoxy-2-propyl acetate 14.55
    2-(2-methoxypropoxy) propanol 12.74
    mesitylene 1.71
    ε-caprolactone 16.31
    p-cymene 2.98
    epichlorohydrin 52.93
    1,1,1-trichloroethane 6.24
    2-aminoethanol 1.2
    morpholine-4-carbaldehyde 37.34
    sulfolane 44.55
    2,2,4-trimethylpentane 0.11
    2-methyltetrahydrofuran 12.21
    n-hexyl acetate 5.51
    isooctane 0.08
    2-(2-butoxyethoxy)ethanol 12.45
    sec-butyl acetate 5.97
    tert-butyl acetate 6.72
    decalin 0.31
    glycerin 3.05
    diglyme 34.72
    acrylic acid 5.36
    isopropyl myristate 4.05
    n-butyric acid 3.76
    acetyl acetate 6.74
    di(2-ethylhexyl) phthalate 5.91
    ethyl propionate 6.34
    nitromethane 19.32
    1,2-diethoxyethane 11.2
    benzonitrile 11.43
    trioctyl phosphate 3.19
    1-bromopropane 2.8
    gamma-valerolactone 42.5
    n-decanol 1.36
    triethyl phosphate 7.2
    4-methyl-2-pentanol 1.24
    propionitrile 3.59
    vinylene carbonate 16.01
    1,1,2-trichlorotrifluoroethane 24.26
    DMS 13.88
    cumene 2.54
    2-octanol 1.06
    2-hexanone 7.71
    octyl acetate 4.15
    limonene 2.92
    1,2-dimethoxyethane 19.22
    ethyl orthosilicate 6.38
    tributyl phosphate 4.39
    diacetone alcohol 9.78
    N,N-dimethylaniline 6.78
    acrylonitrile 8.92
    aniline 6.13
    1,3-propanediol 2.24
    bromobenzene 7.41
    dibromomethane 6.73
    1,1,2,2-tetrachloroethane 24.88
    2-methyl-cyclohexyl acetate 9.01
    tetrabutyl urea 7.33
    diisobutyl methanol 2.35
    2-phenylethanol 8.26
    styrene 3.45
    dioctyl adipate 7.4
    dimethyl sulfate 20.05
    ethyl butyrate 7.16
    methyl lactate 6.44
    butyl lactate 6.11
    diethyl carbonate 6.47
    propanediol butyl ether 4.22
    triethyl orthoformate 7.59
    p-tert-butyltoluene 2.44
    methyl 4-tert-butylbenzoate 11.59
    morpholine 14.72
    tert-butylamine 0.58
    n-dodecanol 1.23
    dimethoxymethane 13.26
    ethylene carbonate 11.16
    cyrene 15.73
    2-ethoxyethyl acetate 12.29
    2-ethylhexyl acetate 7.55
    1,2,4-trichlorobenzene 13.16
    4-methylpyridine 15.63
    dibutyl ether 3.17
    2,6-dimethyl-4-heptanol 2.35
    DEF 9.84
    dimethyl isosorbide 29.45
    tetrachloroethylene 12.66
    eugenol 13.15
    triacetin 12.67
    span 80 8.08
    1,4-butanediol 1.18
    1,1-dichloroethane 5.09
    2-methyl-1-pentanol 2.31
    methyl formate 7.45
    2-methyl-1-butanol 1.22
    n-decane 0.2
    butyronitrile 2.8
    3,7-dimethyl-1-octanol 2.08
    1-chlorooctane 1.18
    1-chlorotetradecane 0.79
    n-nonane 0.13
    undecane 0.17
    tert-butylcyclohexane 0.26
    cyclooctane 0.04
    cyclopentanol 2.6
    tetrahydropyran 7.42
    tert-amyl methyl ether 1.94
    2,5,8-trioxanonane 26.14
    1-hexene 0.52
    2-isopropoxyethanol 5.33
    2,2,2-trifluoroethanol 4.61
    methyl butyrate 8.15

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction