Pyridoxine serinate

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  • Identifiers

    CAS number
    14942-12-2

    Molecular formula
    C11H16N2O5

    SMILES
    CC1=NC=C(C(=C1O)CN[C@@H](CO)C(=O)O)CO

    Safety labels

  • Odor profile

    Fragrance
    Odorless 74.59%
    Sweet 30.73%
    Savory 30.54%
    Milky 24.61%
    Cooling 21.16%
    Bitter 20.54%
    Meaty 17.87%
    Vanilla 17.61%
    Alcoholic 15.86%
    Cooked 15.33%

     

    Flavor
    Odorless 66.23%
    Bitter 56.42%
    Bland 35.46%
    Mild 34.89%
    Sweet-like 26.9%
    Very mild 26.78%
    Yeast 21.07%
    Nitrile 19.32%
    Orange flower 19.09%
    Cooked beef juice 18.9%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -3.9

    pKa est.
    6.58 (neutral)

    Molecular weight
    256.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1238°C

    Flash point

    • 269.56 ˚C est.

  • Synonyms

    • Pyridoxine serinate
    • Pyridoxyl-L-serine
    • Vitamin B6 serine
    • UNII-269I30G86W
    • 269I30G86W
    • 14942-12-2
    • Serine, N-((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridyl)methyl)
    • L-Serine, N-((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl)methyl)-
    • Serine, N-((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridyl)methyl)-, L-
    • DTXSID90164266
    • RefChem:177736
    • DTXCID6086757
    • PYRIDOXINE SERINATE [INCI]
    • SCHEMBL6282607
    • DUJPDBHMHIVXOJ-VIFPVBQESA-N
    • Q27254080
    • N-{[3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl]methyl}-L-serine
    • 14942-12-2

  • Applications

    Pyridoxine serinate (CAS 14942-12-2) is the serine salt form of pyridoxine (vitamin B6) and serves as a vitamin B6 source in various formulations. In practice, it may be used in pharmaceuticals and nutraceuticals, cosmetics/personal care, and as a micronutrient additive in animal feed and agriculture, with potential for food fortification and as an intermediate for the synthesis of other pyridoxine derivatives.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.1
    methanol 0.59
    isopropanol 0.06
    water 10.54
    ethyl acetate 0.06
    n-propanol 0.09
    acetone 0.04
    n-butanol 0.09
    acetonitrile 0.03
    DMF 3.81
    toluene 0.1
    isobutanol 0.08
    1,4-dioxane 0.19
    methyl acetate 0.05
    THF 0.48
    2-butanone 0.1
    n-pentanol 0.08
    sec-butanol 0.12
    n-hexane 0.04
    ethylene glycol 2.57
    NMP 30.21
    cyclohexane 0.08
    DMSO 27.69
    n-butyl acetate 0.09
    n-octanol 0.1
    chloroform 0.04
    n-propyl acetate 0.05
    acetic acid 2.08
    dichloromethane 0.04
    cyclohexanone 0.71
    propylene glycol 1.42
    isopropyl acetate 0.06
    DMAc 15.54
    2-ethoxyethanol 1.51
    isopentanol 0.14
    n-heptane 0.09
    ethyl formate 0.11
    1,2-dichloroethane 0.06
    n-hexanol 0.23
    2-methoxyethanol 3.66
    isobutyl acetate 0.02
    tetrachloromethane 0.08
    n-pentyl acetate 0.12
    transcutol 2.66
    n-heptanol 0.29
    ethylbenzene 0.09
    MIBK 0.14
    2-propoxyethanol 1.62
    tert-butanol 0.27
    MTBE 0.06
    2-butoxyethanol 1.04
    propionic acid 0.47
    o-xylene 0.28
    formic acid 40.7
    diethyl ether 0.04
    m-xylene 0.17
    p-xylene 0.1
    chlorobenzene 0.04
    dimethyl carbonate 0.32
    n-octane 0.04
    formamide 19.68
    cyclopentanone 0.66
    2-pentanone 0.1
    anisole 0.12
    cyclopentyl methyl ether 0.42
    gamma-butyrolactone 1.05
    1-methoxy-2-propanol 1.91
    pyridine 0.27
    3-pentanone 0.18
    furfural 2.87
    n-dodecane 0.01
    diethylene glycol 6.17
    diisopropyl ether 0.05
    tert-amyl alcohol 0.45
    acetylacetone 0.27
    n-hexadecane 0.02
    acetophenone 0.35
    methyl propionate 0.18
    isopentyl acetate 0.14
    trichloroethylene 0.13
    n-nonanol 0.13
    cyclohexanol 0.49
    benzyl alcohol 0.35
    2-ethylhexanol 0.23
    isooctanol 0.26
    dipropyl ether 0.18
    1,2-dichlorobenzene 0.08
    ethyl lactate 0.49
    propylene carbonate 0.54
    n-methylformamide 1.48
    2-pentanol 0.1
    n-pentane 0.03
    1-propoxy-2-propanol 1.0
    1-methoxy-2-propyl acetate 0.46
    2-(2-methoxypropoxy) propanol 1.75
    mesitylene 0.17
    ε-caprolactone 0.8
    p-cymene 0.19
    epichlorohydrin 0.38
    1,1,1-trichloroethane 0.05
    2-aminoethanol 1.65
    morpholine-4-carbaldehyde 8.16
    sulfolane 15.13
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 0.25
    n-hexyl acetate 0.13
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 1.82
    sec-butyl acetate 0.04
    tert-butyl acetate 0.18
    decalin 0.04
    glycerin 14.2
    diglyme 2.95
    acrylic acid 1.17
    isopropyl myristate 0.08
    n-butyric acid 0.42
    acetyl acetate 0.08
    di(2-ethylhexyl) phthalate 0.3
    ethyl propionate 0.09
    nitromethane 1.08
    1,2-diethoxyethane 0.16
    benzonitrile 0.1
    trioctyl phosphate 0.22
    1-bromopropane 0.03
    gamma-valerolactone 2.58
    n-decanol 0.11
    triethyl phosphate 0.34
    4-methyl-2-pentanol 0.12
    propionitrile 0.04
    vinylene carbonate 0.46
    1,1,2-trichlorotrifluoroethane 6.28
    DMS 0.24
    cumene 0.1
    2-octanol 0.14
    2-hexanone 0.09
    octyl acetate 0.11
    limonene 0.26
    1,2-dimethoxyethane 1.02
    ethyl orthosilicate 0.31
    tributyl phosphate 0.2
    diacetone alcohol 1.41
    N,N-dimethylaniline 0.34
    acrylonitrile 0.09
    aniline 0.28
    1,3-propanediol 1.57
    bromobenzene 0.03
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.19
    2-methyl-cyclohexyl acetate 0.26
    tetrabutyl urea 0.49
    diisobutyl methanol 0.21
    2-phenylethanol 0.44
    styrene 0.06
    dioctyl adipate 0.16
    dimethyl sulfate 2.49
    ethyl butyrate 0.14
    methyl lactate 1.69
    butyl lactate 0.48
    diethyl carbonate 0.11
    propanediol butyl ether 1.16
    triethyl orthoformate 0.26
    p-tert-butyltoluene 0.2
    methyl 4-tert-butylbenzoate 1.09
    morpholine 0.41
    tert-butylamine 0.11
    n-dodecanol 0.09
    dimethoxymethane 0.82
    ethylene carbonate 0.28
    cyrene 4.8
    2-ethoxyethyl acetate 0.22
    2-ethylhexyl acetate 0.11
    1,2,4-trichlorobenzene 0.13
    4-methylpyridine 0.21
    dibutyl ether 0.07
    2,6-dimethyl-4-heptanol 0.21
    DEF 0.84
    dimethyl isosorbide 3.27
    tetrachloroethylene 0.31
    eugenol 1.26
    triacetin 0.39
    span 80 1.32
    1,4-butanediol 0.64
    1,1-dichloroethane 0.02
    2-methyl-1-pentanol 0.13
    methyl formate 0.73
    2-methyl-1-butanol 0.16
    n-decane 0.02
    butyronitrile 0.03
    3,7-dimethyl-1-octanol 0.12
    1-chlorooctane 0.04
    1-chlorotetradecane 0.02
    n-nonane 0.02
    undecane 0.02
    tert-butylcyclohexane 0.03
    cyclooctane 0.07
    cyclopentanol 0.45
    tetrahydropyran 0.12
    tert-amyl methyl ether 0.19
    2,5,8-trioxanonane 3.19
    1-hexene 0.05
    2-isopropoxyethanol 0.61
    2,2,2-trifluoroethanol 3.35
    methyl butyrate 0.13

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction