Pymetrozine

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  • Identifiers

    CAS number
    123312-89-0

    Molecular formula
    C10H11N5O

    SMILES
    CC1=NNC(=O)N(C1)/N=C/C2=CN=CC=C2

    Safety labels

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Nutty 55.29%
    Roasted 53.99%
    Popcorn 47.17%
    Odorless 36.14%
    Burnt 28.55%
    Meaty 25.86%
    Cooked 25.28%
    Potato 24.3%
    Earthy 23.18%
    Hazelnut 22.78%

     

    Flavor
    Bitter 80.22%
    Roasted 29.64%
    Odorless 22.83%
    Nutty 21.58%
    Taco 20.75%
    Bread crust 20.62%
    Roasted peanuts 20.1%
    Cereal 19.8%
    Nitrile 19.57%
    Roast 19.56%

     

    Odor impact est.
    Odorless

  • Properties

    pKa est.
    5.22 (weak acid)

    Molecular weight
    217.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    540°C

    Melting point expt.

    • 217 °C

    Flash point

    • 204.23 ˚C est.

    Solubility expt.

    • In ethanol, 2.25; in hexane <0.001 (both g/l @ 20 °C)
    • In water, 290 mg/l @ 25 °C

  • Synonyms

    • Pymetrozine
    • 123312-89-0
    • DTXSID2032637
    • 1,2,4-Triazin-3(2H)-one, 4,5-dihydro-6-methyl-4-[(E)-(3-pyridinylmethylene)amino]-
    • F0G3V7874J
    • DTXCID0012637
    • CHEBI:39311
    • (E)-4,5-dihydro-6-methyl-4-((3-pyridinylmethylene)amino)-1,2,4-triazin-3(2H)-one
    • 1,2,4-Triazin-3(2H)-one, 4,5-dihydro-6-methyl-4-((E)-(3-pyridinylmethylene)amino)-
    • (e)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2h)-one
    • 6-methyl-4-{[(1E)-pyridin-3-ylmethylene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one
    • 6-methyl-4-(((1E)-pyridin-3-ylmethylene)amino)-4,5-dihydro-1,2,4-triazin-3(2H)-one
    • RefChem:177379
    • 6-methyl-4-((E)-(pyridin-3-ylmethylidene)amino)-2,3,4,5-tetrahydro-1,2,4-triazin-3-one
    • 602-927-1
    • pymetrozine (ISO); (E)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one
    • Pymetrozin
    • Fulfill
    • MFCD01632346
    • Plenum
    • 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one
    • CGA 215944
    • HSDB 7054
    • Pymetrozine [ISO:BSI]
    • Pymethrozine
    • UNII-F0G3V7874J
    • EINECS Annex I Index 613-202-00-4
    • 4,5-DIHYDRO-6-METHYL-4-((E)-(3-PYRIDINYLMETHYLENE)AMINO)-1,2,4-TRIAZIN-3(2H)-ONE
    • 4,5-Dihydro-6-methyl-4-[(E)-(3-pyridinylmethylene)amino]-1,2,4-triazin-3(2H)-one
    • Pymetrozine 10 microg/mL in Methanol
    • A 9364A
    • Pymetrozine (Standard)
    • PYMETROZINE [MI]
    • PYMETROZINE [ISO]
    • PYMETROZINE [HSDB]
    • SCHEMBL26437
    • orb1300058
    • CHEMBL1906026
    • SCHEMBL29359367
    • HY-B0821R
    • HY-B0821
    • MSK20295
    • Tox21_300879
    • 6-methyl-4-[(E)-3-pyridylmethyleneamino]-2,5-dihydro-1,2,4-triazin-3-one
    • AKOS015913530
    • AC-9080
    • CS-5903
    • KS-5371
    • 1,2,4-Triazin-3(2H)-one, 4,5-dihydro-6-methyl-4-((3-pyridinylmethylene)amino)-, (E)-
    • NCGC00164310-01
    • NCGC00168332-01
    • NCGC00168332-02
    • NCGC00254783-01
    • SY293206
    • CAS-123312-89-0
    • NS00000443
    • Pymetrozin, PESTANAL(R), analytical standard
    • C18590
    • F87008
    • 312P890
    • Q2119621
    • (E)-6-Methyl-4-[(3-pyridylmethylene)amino]-4,5-dihydro-1,2,4-triazin-3(2H)-one
    • 6-Methyl-4-{(E)-[(pyridin-3-yl)methylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one
    • 123312-89-0

  • Applications

    Pymetrozine (CAS 123312-89-0) is a crop-protection insecticide used to manage sap-sucking pests, particularly aphids and whiteflies. It is applied on both greenhouse and open-field crops, including vegetables, fruits, cereals, and ornamentals, by foliar sprays or soil-directed treatments. The product is commonly used within integrated pest management programs and is compatible with tank-mix strategies where permitted. It serves as a targeted insecticide rather than a broad-spectrum control, and its use is governed by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.14
    methanol 4.92
    isopropanol 1.02
    water 0.09
    ethyl acetate 1.77
    n-propanol 1.24
    acetone 3.88
    n-butanol 0.83
    acetonitrile 3.98
    DMF 16.88
    toluene 1.38
    isobutanol 1.02
    1,4-dioxane 1.58
    methyl acetate 3.09
    THF 5.94
    2-butanone 4.94
    n-pentanol 1.21
    sec-butanol 1.01
    n-hexane 0.04
    ethylene glycol 2.96
    NMP 7.01
    cyclohexane 0.03
    DMSO 28.64
    n-butyl acetate 2.45
    n-octanol 0.23
    chloroform 7.95
    n-propyl acetate 1.99
    acetic acid 7.31
    dichloromethane 13.3
    cyclohexanone 5.01
    propylene glycol 2.53
    isopropyl acetate 1.16
    DMAc 35.72
    2-ethoxyethanol 9.15
    isopentanol 1.37
    n-heptane 0.04
    ethyl formate 3.9
    1,2-dichloroethane 6.72
    n-hexanol 1.09
    2-methoxyethanol 15.52
    isobutyl acetate 1.32
    tetrachloromethane 0.49
    n-pentyl acetate 0.94
    transcutol 35.36
    n-heptanol 0.53
    ethylbenzene 0.9
    MIBK 1.86
    2-propoxyethanol 8.54
    tert-butanol 1.37
    MTBE 0.56
    2-butoxyethanol 4.22
    propionic acid 2.76
    o-xylene 1.27
    formic acid 14.17
    diethyl ether 0.4
    m-xylene 1.24
    p-xylene 1.67
    chlorobenzene 2.78
    dimethyl carbonate 3.1
    n-octane 0.02
    formamide 20.93
    cyclopentanone 6.19
    2-pentanone 2.0
    anisole 2.54
    cyclopentyl methyl ether 1.2
    gamma-butyrolactone 8.46
    1-methoxy-2-propanol 7.93
    pyridine 9.76
    3-pentanone 2.0
    furfural 24.16
    n-dodecane 0.02
    diethylene glycol 15.19
    diisopropyl ether 0.17
    tert-amyl alcohol 1.32
    acetylacetone 4.25
    n-hexadecane 0.02
    acetophenone 5.33
    methyl propionate 2.85
    isopentyl acetate 2.9
    trichloroethylene 17.63
    n-nonanol 0.3
    cyclohexanol 0.82
    benzyl alcohol 5.46
    2-ethylhexanol 0.87
    isooctanol 0.55
    dipropyl ether 0.72
    1,2-dichlorobenzene 3.64
    ethyl lactate 3.92
    propylene carbonate 6.01
    n-methylformamide 9.27
    2-pentanol 0.5
    n-pentane 0.02
    1-propoxy-2-propanol 4.78
    1-methoxy-2-propyl acetate 5.36
    2-(2-methoxypropoxy) propanol 9.59
    mesitylene 0.69
    ε-caprolactone 4.59
    p-cymene 0.93
    epichlorohydrin 16.78
    1,1,1-trichloroethane 2.38
    2-aminoethanol 3.7
    morpholine-4-carbaldehyde 14.45
    sulfolane 16.19
    2,2,4-trimethylpentane 0.04
    2-methyltetrahydrofuran 1.88
    n-hexyl acetate 0.92
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 10.0
    sec-butyl acetate 1.27
    tert-butyl acetate 1.47
    decalin 0.07
    glycerin 8.1
    diglyme 19.19
    acrylic acid 5.08
    isopropyl myristate 0.64
    n-butyric acid 3.07
    acetyl acetate 1.91
    di(2-ethylhexyl) phthalate 2.64
    ethyl propionate 2.08
    nitromethane 16.61
    1,2-diethoxyethane 2.6
    benzonitrile 6.3
    trioctyl phosphate 1.06
    1-bromopropane 1.5
    gamma-valerolactone 14.73
    n-decanol 0.27
    triethyl phosphate 2.79
    4-methyl-2-pentanol 0.61
    propionitrile 3.61
    vinylene carbonate 8.11
    1,1,2-trichlorotrifluoroethane 22.61
    DMS 3.45
    cumene 0.8
    2-octanol 0.23
    2-hexanone 2.43
    octyl acetate 0.81
    limonene 0.84
    1,2-dimethoxyethane 9.82
    ethyl orthosilicate 2.14
    tributyl phosphate 1.65
    diacetone alcohol 5.0
    N,N-dimethylaniline 2.55
    acrylonitrile 8.21
    aniline 3.81
    1,3-propanediol 3.97
    bromobenzene 2.61
    dibromomethane 5.46
    1,1,2,2-tetrachloroethane 10.5
    2-methyl-cyclohexyl acetate 2.7
    tetrabutyl urea 2.71
    diisobutyl methanol 0.71
    2-phenylethanol 4.61
    styrene 1.12
    dioctyl adipate 2.02
    dimethyl sulfate 9.06
    ethyl butyrate 2.39
    methyl lactate 6.13
    butyl lactate 2.72
    diethyl carbonate 2.57
    propanediol butyl ether 3.98
    triethyl orthoformate 2.14
    p-tert-butyltoluene 0.74
    methyl 4-tert-butylbenzoate 4.9
    morpholine 3.12
    tert-butylamine 0.51
    n-dodecanol 0.23
    dimethoxymethane 6.74
    ethylene carbonate 4.6
    cyrene 10.45
    2-ethoxyethyl acetate 3.0
    2-ethylhexyl acetate 2.04
    1,2,4-trichlorobenzene 5.34
    4-methylpyridine 7.08
    dibutyl ether 0.35
    2,6-dimethyl-4-heptanol 0.71
    DEF 3.89
    dimethyl isosorbide 15.19
    tetrachloroethylene 6.01
    eugenol 6.88
    triacetin 3.52
    span 80 4.49
    1,4-butanediol 2.3
    1,1-dichloroethane 2.86
    2-methyl-1-pentanol 1.82
    methyl formate 8.36
    2-methyl-1-butanol 1.2
    n-decane 0.02
    butyronitrile 2.5
    3,7-dimethyl-1-octanol 0.61
    1-chlorooctane 0.12
    1-chlorotetradecane 0.1
    n-nonane 0.02
    undecane 0.02
    tert-butylcyclohexane 0.06
    cyclooctane 0.02
    cyclopentanol 1.07
    tetrahydropyran 0.91
    tert-amyl methyl ether 0.72
    2,5,8-trioxanonane 16.1
    1-hexene 0.23
    2-isopropoxyethanol 4.63
    2,2,2-trifluoroethanol 4.94
    methyl butyrate 3.22

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction