Propyzamide

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  • Identifiers

    CAS number
    23950-58-5

    Molecular formula
    C12H11Cl2NO

    SMILES
    CC(C)(C#C)NC(=O)C1=CC(=CC(=C1)Cl)Cl

    Safety labels

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 34.06%
    Citrus 32.11%
    Dry 29.28%
    Woody 28.6%
    Grapefruit 27.5%
    Floral 25.63%
    Animal 25.14%
    Musk 23.93%
    Fruity 23.77%
    Grape 23.46%

     

    Flavor
    Bitter 71.4%
    Odorless 38.24%
    Bland 25.55%
    Mild 21.0%
    Nitrile 19.64%
    Sweet-like 18.62%
    Cedarleaf 18.27%
    Very strong 17.82%
    Orange flower 17.61%
    Taco 17.6%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.2

    pKa est.
    6.38 (neutral)

    Molecular weight
    256.12 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    380°C

    Melting point expt.

    • 155-156 °C
    • Decomposes above melting point; in solution for 28 days (pH 5-9, 20 °C) < 10% loss.

    Flash point

    • 151.64 ˚C est.

    Solubility expt.

    • In water - 15 mg/l (25 °C). In methanol, isopropanol 150, cyclohexanone, methyl ethyl ketone 200, dimethyl sulfoxide 330 (all in g/l). Moderately soluble in benzene, xylene, carbon tetrachloride. Sightly soluble in petroleum ether.
    • SOL IN MANY ALIPHATIC & AROMATIC SOLVENTS.

  • Synonyms

    • Propyzamide
    • 23950-58-5
    • PRONAMIDE
    • 3,5-Dichloro-N-(1,1-dimethylpropynyl)benzamide
    • 3,5-dichloro-N-(2-methylbut-3-yn-2-yl)benzamide
    • KERB
    • Pronamid
    • 3,5-Dichloro-N-(1,1-dimethyl-2-propynyl)benzamide
    • Caswell No. 306A
    • Propyzamide [BSI:ISO]
    • 3,5-Dichloro-N-(1,1-dimethylprop-2-ynyl)benzamide
    • RCRA waste number U192
    • Propyzamide [ISO]
    • KERB 50W
    • RH 315
    • CCRIS 1413
    • Promamide
    • Rustler
    • Benzamide, 3,5-dichloro-N-(1,1-dimethyl-2-propynyl)-
    • HSDB 5118
    • N-(1,1-Dimethylpropynyl)-3,5-dichlorobenzamide
    • Kerb Flo
    • Campbell's rapier
    • EINECS 245-951-4
    • EPA Pesticide Chemical Code 101701
    • BRN 0882391
    • Kerb propyzamide 50
    • DTXSID2020420
    • UNII-2EZ95375S0
    • CHEBI:34935
    • PROPYZAMIDE [MI]
    • MFCD00055346
    • PROPYZAMIDE [HSDB]
    • DTXCID80420
    • PHNUZKMIPFFYSO-UHFFFAOYSA-
    • 3,5-Dichloro(N-1,1-dimethyl-2-propynyl)benzamide
    • 2EZ95375S0
    • 3,5-dichloro-N-(1,1-dimethyl-2-propyn-1-yl)benzamide
    • Propyzamide 10 microg/mL in Cyclohexane
    • Clanex
    • Propyzamide 100 microg/mL in Acetonitrile
    • Propyzamide, analytical standard
    • 3,5-dichloro-N-(1,1-dimethylprop-2-yn-1-yl)benzamide
    • propisamide
    • propizamide
    • Pronamide (Kerb)
    • CAS-23950-58-5
    • RH-315
    • RCRA waste no. U192
    • SCHEMBL55124
    • 3,5-Dichloro-N-(2-methyl-3-butyn-2-yl)benzamide
    • BIDD:ER0426
    • 3,5-Dichloro-N-(1,1-dimethyl-2-propynyl) benzamide
    • Benzamide, 3,5-dichloro-N-(1,1-dimethyl-2-propynyl
    • CHEMBL283487
    • CS-D1356
    • Tox21_201413
    • Tox21_301164
    • AKOS010651566
    • Pronamide (Kerb), analytical standard
    • DS-1304
    • NCGC00168331-01
    • NCGC00168331-02
    • NCGC00168331-03
    • NCGC00255062-01
    • NCGC00258964-01
    • SY030062
    • 3,5DichloroN(1,1dimethylpropynyl)benzamide
    • N(1,1Dimethylpropynyl)3,5dichlorobenzamide
    • 3,5DichloroN(1,1dimethyl2propynyl)benzamide
    • 3,5DichloroN(1,1dimethylprop2ynyl)benzamide
    • NS00000560
    • P2374
    • Benzamide, 3,5dichloroN(1,1dimethyl2propynyl)
    • Propyzamide, PESTANAL(R), analytical standard
    • N- (1',1'-dimethylpropynyl)-3,5-dichlorobenzamide
    • N-(1',1'-dimethylpropynyl)-3,5-dichlorobenzamide
    • N-(1,1-dimethyl-2-propynyl)-3,5-dichlorobenzamide
    • Q2113173
    • BENZAMIDE, 3,5-DICHLORO-N-(1,1-DIMETHYL-2-PROPYNYL)
    • Pronamide, 3,5-Dichloro-N-(1,1-dimethyl-2-propynyl)benzamide

  • Applications

    Propyzamide is primarily used as a soil-applied herbicide in agriculture to control annual grasses and a range of broadleaf weeds, notably in crops such as potatoes, beets, and cereals. It is formulated as the active ingredient in various crop protection products (for example emulsifiable concentrates, suspension concentrates, and wettable powders) and is applied as a pre-emergence or early post-emergence treatment depending on the crop and local label. It is commonly used within integrated weed management programs to provide residual soil activity and to complement other herbicides. Its use is subject to local regulations and label constraints, with application timing and rate defined by crop, soil conditions, and weed pressure.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 52.27
    methanol 67.73
    isopropanol 22.29
    water 0.19
    ethyl acetate 56.65
    n-propanol 39.57
    acetone 111.83
    n-butanol 32.04
    acetonitrile 46.0
    DMF 449.05
    toluene 11.07
    isobutanol 25.46
    1,4-dioxane 65.33
    methyl acetate 78.94
    THF 164.52
    2-butanone 100.4
    n-pentanol 30.86
    sec-butanol 29.04
    n-hexane 1.1
    ethylene glycol 21.84
    NMP 237.28
    cyclohexane 0.92
    DMSO 190.69
    n-butyl acetate 52.25
    n-octanol 18.95
    chloroform 139.52
    n-propyl acetate 54.88
    acetic acid 70.74
    dichloromethane 101.73
    cyclohexanone 83.62
    propylene glycol 29.47
    isopropyl acetate 40.16
    DMAc 425.44
    2-ethoxyethanol 80.88
    isopentanol 27.52
    n-heptane 1.39
    ethyl formate 60.79
    1,2-dichloroethane 58.07
    n-hexanol 32.83
    2-methoxyethanol 125.25
    isobutyl acetate 38.67
    tetrachloromethane 9.85
    n-pentyl acetate 35.69
    transcutol 148.01
    n-heptanol 21.75
    ethylbenzene 12.19
    MIBK 46.48
    2-propoxyethanol 89.72
    tert-butanol 26.04
    MTBE 30.85
    2-butoxyethanol 60.49
    propionic acid 49.07
    o-xylene 11.2
    formic acid 58.02
    diethyl ether 30.32
    m-xylene 10.54
    p-xylene 16.72
    chlorobenzene 28.86
    dimethyl carbonate 61.54
    n-octane 0.71
    formamide 90.03
    cyclopentanone 139.6
    2-pentanone 68.82
    anisole 60.48
    cyclopentyl methyl ether 47.04
    gamma-butyrolactone 147.08
    1-methoxy-2-propanol 85.71
    pyridine 75.85
    3-pentanone 55.98
    furfural 163.28
    n-dodecane 0.81
    diethylene glycol 78.55
    diisopropyl ether 7.65
    tert-amyl alcohol 31.65
    acetylacetone 92.93
    n-hexadecane 0.91
    acetophenone 68.57
    methyl propionate 68.9
    isopentyl acetate 49.63
    trichloroethylene 161.47
    n-nonanol 17.77
    cyclohexanol 20.74
    benzyl alcohol 50.23
    2-ethylhexanol 21.82
    isooctanol 18.59
    dipropyl ether 23.28
    1,2-dichlorobenzene 35.04
    ethyl lactate 47.51
    propylene carbonate 91.7
    n-methylformamide 127.81
    2-pentanol 18.98
    n-pentane 0.87
    1-propoxy-2-propanol 59.11
    1-methoxy-2-propyl acetate 74.21
    2-(2-methoxypropoxy) propanol 65.05
    mesitylene 6.8
    ε-caprolactone 80.49
    p-cymene 11.26
    epichlorohydrin 159.48
    1,1,1-trichloroethane 45.1
    2-aminoethanol 39.04
    morpholine-4-carbaldehyde 185.58
    sulfolane 164.28
    2,2,4-trimethylpentane 1.23
    2-methyltetrahydrofuran 77.18
    n-hexyl acetate 42.23
    isooctane 0.75
    2-(2-butoxyethoxy)ethanol 71.6
    sec-butyl acetate 37.71
    tert-butyl acetate 44.94
    decalin 1.44
    glycerin 52.23
    diglyme 133.29
    acrylic acid 57.33
    isopropyl myristate 18.17
    n-butyric acid 52.5
    acetyl acetate 44.43
    di(2-ethylhexyl) phthalate 26.98
    ethyl propionate 52.04
    nitromethane 172.51
    1,2-diethoxyethane 46.35
    benzonitrile 50.99
    trioctyl phosphate 19.13
    1-bromopropane 25.95
    gamma-valerolactone 188.0
    n-decanol 13.18
    triethyl phosphate 32.05
    4-methyl-2-pentanol 15.3
    propionitrile 41.83
    vinylene carbonate 89.07
    1,1,2-trichlorotrifluoroethane 162.0
    DMS 52.48
    cumene 10.46
    2-octanol 15.01
    2-hexanone 61.23
    octyl acetate 24.83
    limonene 14.39
    1,2-dimethoxyethane 134.93
    ethyl orthosilicate 27.14
    tributyl phosphate 22.87
    diacetone alcohol 64.4
    N,N-dimethylaniline 45.63
    acrylonitrile 62.9
    aniline 31.43
    1,3-propanediol 44.47
    bromobenzene 24.37
    dibromomethane 52.86
    1,1,2,2-tetrachloroethane 121.54
    2-methyl-cyclohexyl acetate 43.17
    tetrabutyl urea 34.43
    diisobutyl methanol 12.16
    2-phenylethanol 49.28
    styrene 16.6
    dioctyl adipate 33.59
    dimethyl sulfate 111.65
    ethyl butyrate 44.92
    methyl lactate 62.54
    butyl lactate 41.94
    diethyl carbonate 36.79
    propanediol butyl ether 59.52
    triethyl orthoformate 34.48
    p-tert-butyltoluene 10.89
    methyl 4-tert-butylbenzoate 52.87
    morpholine 94.62
    tert-butylamine 13.33
    n-dodecanol 9.67
    dimethoxymethane 136.07
    ethylene carbonate 63.21
    cyrene 84.66
    2-ethoxyethyl acetate 56.75
    2-ethylhexyl acetate 39.5
    1,2,4-trichlorobenzene 46.99
    4-methylpyridine 75.42
    dibutyl ether 15.98
    2,6-dimethyl-4-heptanol 12.16
    DEF 97.87
    dimethyl isosorbide 108.91
    tetrachloroethylene 67.13
    eugenol 62.66
    triacetin 57.99
    span 80 48.27
    1,4-butanediol 25.3
    1,1-dichloroethane 51.18
    2-methyl-1-pentanol 29.79
    methyl formate 109.9
    2-methyl-1-butanol 28.86
    n-decane 1.28
    butyronitrile 42.38
    3,7-dimethyl-1-octanol 18.85
    1-chlorooctane 8.92
    1-chlorotetradecane 3.67
    n-nonane 1.06
    undecane 0.99
    tert-butylcyclohexane 1.72
    cyclooctane 0.4
    cyclopentanol 30.99
    tetrahydropyran 45.08
    tert-amyl methyl ether 31.47
    2,5,8-trioxanonane 91.94
    1-hexene 8.33
    2-isopropoxyethanol 55.36
    2,2,2-trifluoroethanol 48.55
    methyl butyrate 70.24

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction