Propylparaben Sodium

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  • Identifiers

    CAS number
    35285-69-9

    Molecular formula
    C10H11NaO3

    SMILES
    CCCOC(=O)C1=CC=C(C=C1)[O-].[Na+]

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Sweet 66.74%
    Floral 57.28%
    Phenolic 46.04%
    Balsamic 43.36%
    Vanilla 42.69%
    Powdery 37.51%
    Aromatic 35.06%
    Fruity 34.48%
    Grape 34.29%
    Herbal 30.87%

     

    Flavor
    Sweet 58.21%
    Balsam 52.24%
    Floral 47.59%
    Powdery 42.24%
    Fruity 40.32%
    Wintergreen 39.68%
    Bitter 39.38%
    Balsamic 33.78%
    Grape 31.62%
    Vanilla 31.38%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    6.44 (neutral)

    Molecular weight
    202.18 g/mol

    Flash point

    • 116.96 ˚C est.

  • Synonyms

    • 35285-69-9
    • Propylparaben sodium
    • Sodium propylparaben
    • Propyl 4-hydroxybenzoate sodium salt
    • Sodium propyl 4-hydroxybenzoate
    • Caswell No. 714A
    • sodium propyl paraben
    • Sodium propyl hydroxybenzoate
    • Propylparaben sodium [USAN]
    • Propyl p-hydroxybenzoate, sodium salt
    • Natrium propyl 4-hydroxybenzoat
    • Sodium Propyl Parahydroxybenzoate
    • Propylparaben, sodium salt
    • Propyl-4-hydroxybenzoat natriumsalz
    • EINECS 252-488-1
    • UNII-625NNB0G9N
    • EPA Pesticide Chemical Code 061204
    • 625NNB0G9N
    • Propylparaben sodium [USAN:NF]
    • Propylparaben sodium (NF)
    • DTXSID3042348
    • PROPYLPARABEN SODIUM [II]
    • 4-Hydroxybenzoic acid, propyl ester, sodium salt
    • SODIUM PROPYL HYDROXYBENZOATE [MART.]
    • SODIUM PROPYL P-HYDROXYBENZOATE (E 217)
    • SODIUM PROPYL PARAHYDROXYBENZOATE [EP MONOGRAPH]
    • PROPYLPARABEN SODIUM (II)
    • BENZOIC ACID, p-HYDROXY-, PROPYL ESTER, SODIUM DERIV.
    • BENZOIC ACID, 4-HYDROXY-, PROPYL ESTER, SODIUM SALT (1:1)
    • SODIUM PROPYL HYDROXYBENZOATE (MART.)
    • SODIUM PROPYL PARAHYDROXYBENZOATE (EP MONOGRAPH)
    • RefChem:176555
    • DTXCID1022348
    • SODIUM PROPYLPARABEN [INCI]
    • 252-488-1
    • E-217
    • Sodium 4-(propoxycarbonyl)phenolate
    • Parasept
    • sodium;4-propoxycarbonylphenolate
    • MFCD00016477
    • Benzoic acid, 4-hydroxy-, propyl ester, sodium salt
    • E217
    • Propylparaben (sodium)
    • 4-Hydroxybenzoic acid-propyl ester sodium
    • Sodium 4-propoxycarbonylphenoxide
    • sodium propyl p-hydroxybenzoate
    • sodium,4-propoxycarbonylphenolate
    • propyl paraben sodium
    • MSK2515Na
    • SCHEMBL48862
    • orb1690588
    • CHEMBL2107021
    • HY-N2026A
    • Sodium propyl-p-hydroxyl benzoate
    • IXMINYBUNCWGER-UHFFFAOYSA-M
    • EBC-76139
    • AKOS015961951
    • FS31818
    • AC-15528
    • AS-14864
    • Sodium Propyl Paraben IP/BP/USP/Ph.Eur
    • DB-048766
    • CS-0128919
    • NS00093581
    • D02459
    • E75928
    • Q3963919
    • Propyl 4-hydroxybenzoate sodium salt, tested according to Ph.Eur.
    • 35285-69-9

  • Applications

    Propylparaben Sodium (CAS 35285-69-9) is the sodium salt of propylparaben, a preservative used to inhibit microbial growth in aqueous formulations. Its good water solubility makes it suitable for use in water-based cosmetic and personal care products (creams, lotions, shampoos), as well as in pharmaceutical topical and oral formulations requiring preservation. Beyond cosmetics and pharmaceuticals, it is encountered in household cleaning products to extend shelf life and stabilize fragrance systems, and in coatings/inks or polymer dispersions where aqueous systems benefit from antimicrobial protection. Its use is formulation- and region-dependent, subject to local regulations and limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 421.52
    methanol 560.53
    isopropanol 339.74
    water 0.41
    ethyl acetate 626.38
    n-propanol 311.99
    acetone 1067.41
    n-butanol 333.33
    acetonitrile 589.39
    DMF 1705.32
    toluene 248.2
    isobutanol 251.21
    1,4-dioxane 719.6
    methyl acetate 713.94
    THF 746.92
    2-butanone 748.46
    n-pentanol 298.83
    sec-butanol 326.24
    n-hexane 15.31
    ethylene glycol 118.27
    NMP 1036.56
    cyclohexane 17.82
    DMSO 1500.28
    n-butyl acetate 613.73
    n-octanol 163.35
    chloroform 1013.85
    n-propyl acetate 538.78
    acetic acid 820.62
    dichloromethane 1228.92
    cyclohexanone 760.07
    propylene glycol 128.38
    isopropyl acetate 348.84
    DMAc 1098.51
    2-ethoxyethanol 525.41
    isopentanol 335.98
    n-heptane 8.69
    ethyl formate 435.8
    1,2-dichloroethane 934.55
    n-hexanol 247.97
    2-methoxyethanol 726.64
    isobutyl acetate 264.59
    tetrachloromethane 57.78
    n-pentyl acetate 277.77
    transcutol 2306.44
    n-heptanol 118.42
    ethylbenzene 181.2
    MIBK 340.48
    2-propoxyethanol 450.95
    tert-butanol 522.66
    MTBE 436.56
    2-butoxyethanol 285.5
    propionic acid 424.93
    o-xylene 185.82
    formic acid 283.63
    diethyl ether 388.08
    m-xylene 189.39
    p-xylene 219.43
    chlorobenzene 445.36
    dimethyl carbonate 263.47
    n-octane 6.75
    formamide 636.97
    cyclopentanone 857.61
    2-pentanone 578.36
    anisole 475.04
    cyclopentyl methyl ether 337.54
    gamma-butyrolactone 1079.66
    1-methoxy-2-propanol 545.37
    pyridine 721.16
    3-pentanone 375.79
    furfural 975.58
    n-dodecane 9.92
    diethylene glycol 386.15
    diisopropyl ether 106.13
    tert-amyl alcohol 483.18
    acetylacetone 691.29
    n-hexadecane 11.86
    acetophenone 500.19
    methyl propionate 507.9
    isopentyl acetate 446.37
    trichloroethylene 1845.45
    n-nonanol 141.62
    cyclohexanol 273.82
    benzyl alcohol 379.94
    2-ethylhexanol 162.86
    isooctanol 106.29
    dipropyl ether 161.3
    1,2-dichlorobenzene 393.75
    ethyl lactate 217.36
    propylene carbonate 523.53
    n-methylformamide 741.19
    2-pentanol 264.32
    n-pentane 11.72
    1-propoxy-2-propanol 323.41
    1-methoxy-2-propyl acetate 408.61
    2-(2-methoxypropoxy) propanol 361.57
    mesitylene 103.34
    ε-caprolactone 670.97
    p-cymene 83.17
    epichlorohydrin 1153.36
    1,1,1-trichloroethane 483.92
    2-aminoethanol 219.05
    morpholine-4-carbaldehyde 998.7
    sulfolane 1167.76
    2,2,4-trimethylpentane 15.57
    2-methyltetrahydrofuran 572.64
    n-hexyl acetate 430.63
    isooctane 11.09
    2-(2-butoxyethoxy)ethanol 535.19
    sec-butyl acetate 305.34
    tert-butyl acetate 385.63
    decalin 23.51
    glycerin 210.72
    diglyme 964.59
    acrylic acid 464.63
    isopropyl myristate 135.98
    n-butyric acid 503.86
    acetyl acetate 398.68
    di(2-ethylhexyl) phthalate 124.47
    ethyl propionate 386.24
    nitromethane 1619.05
    1,2-diethoxyethane 514.14
    benzonitrile 525.01
    trioctyl phosphate 91.34
    1-bromopropane 333.79
    gamma-valerolactone 1041.73
    n-decanol 107.52
    triethyl phosphate 134.33
    4-methyl-2-pentanol 156.85
    propionitrile 410.13
    vinylene carbonate 570.14
    1,1,2-trichlorotrifluoroethane 689.81
    DMS 394.59
    cumene 109.71
    2-octanol 101.78
    2-hexanone 492.01
    octyl acetate 188.62
    limonene 118.32
    1,2-dimethoxyethane 856.92
    ethyl orthosilicate 120.2
    tributyl phosphate 136.33
    diacetone alcohol 469.12
    N,N-dimethylaniline 262.3
    acrylonitrile 695.61
    aniline 361.91
    1,3-propanediol 329.34
    bromobenzene 443.23
    dibromomethane 690.31
    1,1,2,2-tetrachloroethane 1179.37
    2-methyl-cyclohexyl acetate 217.63
    tetrabutyl urea 172.44
    diisobutyl methanol 96.79
    2-phenylethanol 301.03
    styrene 276.81
    dioctyl adipate 213.98
    dimethyl sulfate 414.97
    ethyl butyrate 337.67
    methyl lactate 252.99
    butyl lactate 226.74
    diethyl carbonate 241.8
    propanediol butyl ether 339.78
    triethyl orthoformate 190.15
    p-tert-butyltoluene 79.22
    methyl 4-tert-butylbenzoate 277.28
    morpholine 803.28
    tert-butylamine 270.2
    n-dodecanol 79.34
    dimethoxymethane 674.6
    ethylene carbonate 420.48
    cyrene 284.94
    2-ethoxyethyl acetate 434.73
    2-ethylhexyl acetate 323.83
    1,2,4-trichlorobenzene 468.03
    4-methylpyridine 826.23
    dibutyl ether 220.18
    2,6-dimethyl-4-heptanol 96.79
    DEF 701.29
    dimethyl isosorbide 453.72
    tetrachloroethylene 664.62
    eugenol 307.34
    triacetin 393.8
    span 80 253.74
    1,4-butanediol 160.56
    1,1-dichloroethane 702.55
    2-methyl-1-pentanol 298.67
    methyl formate 605.9
    2-methyl-1-butanol 303.52
    n-decane 15.13
    butyronitrile 395.61
    3,7-dimethyl-1-octanol 170.44
    1-chlorooctane 99.56
    1-chlorotetradecane 40.2
    n-nonane 12.68
    undecane 12.15
    tert-butylcyclohexane 22.56
    cyclooctane 6.63
    cyclopentanol 246.95
    tetrahydropyran 518.56
    tert-amyl methyl ether 324.85
    2,5,8-trioxanonane 606.41
    1-hexene 121.57
    2-isopropoxyethanol 377.67
    2,2,2-trifluoroethanol 246.67
    methyl butyrate 547.91

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction