Propylene glycol mono-t-butyl ether

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  • Identifiers

    CAS number
    57018-52-7

    Molecular formula
    C7H16O2

    SMILES
    CC(COC(C)(C)C)O

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Alcoholic 55.05%
    Fermented 54.12%
    Ethereal 51.33%
    Fruity 47.12%
    Solvent 36.02%
    Mint 34.05%
    Oily 30.23%
    Green 30.15%
    Camphoreous 29.36%
    Musty 28.28%

     

    Flavor
    Fruity 42.24%
    Green 42.08%
    Oily 35.67%
    Herbal 30.07%
    Bitter 27.71%
    Sweet 26.88%
    Pungent 26.38%
    Earthy 26.11%
    Tropical 26.06%
    Mild 25.23%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.8

    pKa est.
    9.28 (weak base)

    Molecular weight
    132.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point

    • 304 °F at 760 mmHg (NTP, 1992)
    • 151 °C

    Flash point

    • 53.25 ˚C est.
    • 112 °F (NTP, 1992)
    • 112 °F
    • 44.4 °C o.c.

    Solubility expt.

    • greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)
    • In water, 1.73X10+5 mg/L at 20 °C
    • Solubility in water, g/100ml at 19 °C: >=10

  • Synonyms

    • 1-tert-butoxy-2-propanol
    • 57018-52-7
    • 1-tert-Butoxypropan-2-ol
    • 2-Propanol, 1-(1,1-dimethylethoxy)-
    • Propylene glycol mono-t-butyl ether
    • Propanol, tert-butoxy-
    • Propylene glycol t-butyl ether
    • 1-[(2-methylpropan-2-yl)oxy]propan-2-ol
    • Propylene glycol mono-t-buthyl ether
    • 1-(tert-butoxy)propan-2-ol
    • CCRIS 9039
    • HSDB 7295
    • BRN 1734501
    • DTXSID8025967
    • Propanol, (1,1-dimethylethoxy)-
    • 1-t-butoxy-2-propanol
    • 1-(1,1-Dimethylethoxy)-2-propanol
    • DTXCID905967
    • CHEBI:82413
    • EC 406-180-0
    • 1-METHYL-2-TERT-BUTOXYETHANOL
    • 03077MV85B
    • PROPYLENE GLYCOL 1-(TERT-BUTYL ETHER)
    • 1-tert-butoxy-propan-2-ol
    • tertButoxypropanol
    • UNII-03077MV85B
    • PtBGE
    • Propylene glycol 1-tert-butyl ether
    • 1tertButoxy2propanol
    • Propanol, tertbutoxy
    • MFCD00077674
    • PGTBE
    • 1-t-butoxypropan-2-ol
    • tertiary butoxy-propan-2-ol
    • Propanol, tertbutoxy (8CI)
    • SCHEMBL35599
    • Propylene glycol tbutyl ether
    • 1-tertiary-butoxypropan-2-ol
    • 1-(tert-Butoxy)-2-propanol
    • Propanol, tert-butoxy-(8CI)
    • Propanol, (1,1dimethylethoxy)
    • CHEMBL1456695
    • 1-Methyl-2-(tert-butoxy)ethanol
    • 1-tert-Butoxy-2-propanol, 99%
    • 2Propanol, 1(1,1dimethylethoxy)
    • Tox21_200655
    • MFCD07366996
    • AKOS009157151
    • NCGC00090775-01
    • NCGC00090775-02
    • NCGC00258209-01
    • AS-44317
    • PROPYLENE GLYCOL MON-T-BUTYL ETHER
    • Propylene glycol mono-tertiary-butyl ether
    • CAS-57018-52-7
    • DB-016714
    • DB-016792
    • B5840
    • NS00005729
    • PROPYLENE GLYCOL T-BUTYL ETHER [INCI]
    • A10548
    • C19356
    • Q2847602
    • F8883-3578
    • 611-448-7

  • Applications

    Propylene glycol mono-t-butyl ether (CAS 57018-52-7) is commonly used as a solvent in industrial coatings and printing inks, enabling dissolution of resins and additives and improving volatility characteristics. It also serves as a solvent in cleaning and degreasing formulations for industrial equipment, and as a co-solvent or processing medium in polymer and plastics formulations. Additionally, it is used as an intermediate in chemical synthesis and can act as a processing aid in formulation development, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 120.82
    methanol 223.57
    isopropanol 136.63
    water 21.77
    ethyl acetate 63.12
    n-propanol 129.62
    acetone 80.36
    n-butanol 116.32
    acetonitrile 53.34
    DMF 166.89
    toluene 36.74
    isobutanol 106.9
    1,4-dioxane 123.92
    methyl acetate 87.69
    THF 149.79
    2-butanone 89.83
    n-pentanol 69.44
    sec-butanol 134.71
    n-hexane 39.41
    ethylene glycol 115.7
    NMP 183.6
    cyclohexane 34.78
    DMSO 107.83
    n-butyl acetate 70.16
    n-octanol 114.75
    chloroform 223.17
    n-propyl acetate 43.39
    acetic acid 113.1
    dichloromethane 126.31
    cyclohexanone 119.17
    propylene glycol 180.53
    isopropyl acetate 53.02
    DMAc 236.37
    2-ethoxyethanol 107.93
    isopentanol 96.4
    n-heptane 43.95
    ethyl formate 54.84
    1,2-dichloroethane 65.63
    n-hexanol 155.85
    2-methoxyethanol 192.32
    isobutyl acetate 42.38
    tetrachloromethane 68.78
    n-pentyl acetate 56.72
    transcutol 248.6
    n-heptanol 94.49
    ethylbenzene 34.83
    MIBK 54.33
    2-propoxyethanol 192.42
    tert-butanol 183.07
    MTBE 119.56
    2-butoxyethanol 123.88
    propionic acid 129.98
    o-xylene 47.78
    formic acid 75.09
    diethyl ether 65.25
    m-xylene 40.09
    p-xylene 49.18
    chlorobenzene 49.28
    dimethyl carbonate 39.49
    n-octane 20.4
    formamide 47.04
    cyclopentanone 128.25
    2-pentanone 63.11
    anisole 67.32
    cyclopentyl methyl ether 89.47
    gamma-butyrolactone 130.07
    1-methoxy-2-propanol 174.17
    pyridine 66.77
    3-pentanone 63.24
    furfural 128.55
    n-dodecane 19.01
    diethylene glycol 178.35
    diisopropyl ether 36.96
    tert-amyl alcohol 173.14
    acetylacetone 73.44
    n-hexadecane 19.53
    acetophenone 68.21
    methyl propionate 72.39
    isopentyl acetate 77.62
    trichloroethylene 135.8
    n-nonanol 98.52
    cyclohexanol 120.98
    benzyl alcohol 66.06
    2-ethylhexanol 103.78
    isooctanol 73.07
    dipropyl ether 77.07
    1,2-dichlorobenzene 62.47
    ethyl lactate 69.61
    propylene carbonate 98.38
    n-methylformamide 80.52
    2-pentanol 90.85
    n-pentane 31.86
    1-propoxy-2-propanol 163.35
    1-methoxy-2-propyl acetate 101.69
    2-(2-methoxypropoxy) propanol 154.77
    mesitylene 33.55
    ε-caprolactone 117.42
    p-cymene 48.86
    epichlorohydrin 101.31
    1,1,1-trichloroethane 106.82
    2-aminoethanol 146.64
    morpholine-4-carbaldehyde 194.62
    sulfolane 177.48
    2,2,4-trimethylpentane 29.65
    2-methyltetrahydrofuran 121.55
    n-hexyl acetate 106.97
    isooctane 19.41
    2-(2-butoxyethoxy)ethanol 160.93
    sec-butyl acetate 41.63
    tert-butyl acetate 74.46
    decalin 24.92
    glycerin 227.9
    diglyme 220.64
    acrylic acid 116.89
    isopropyl myristate 57.18
    n-butyric acid 114.94
    acetyl acetate 54.48
    di(2-ethylhexyl) phthalate 66.01
    ethyl propionate 48.96
    nitromethane 101.35
    1,2-diethoxyethane 69.22
    benzonitrile 63.64
    trioctyl phosphate 57.02
    1-bromopropane 62.8
    gamma-valerolactone 155.21
    n-decanol 79.7
    triethyl phosphate 56.84
    4-methyl-2-pentanol 68.23
    propionitrile 70.35
    vinylene carbonate 91.45
    1,1,2-trichlorotrifluoroethane 178.62
    DMS 77.94
    cumene 36.89
    2-octanol 72.12
    2-hexanone 51.37
    octyl acetate 71.73
    limonene 71.93
    1,2-dimethoxyethane 143.7
    ethyl orthosilicate 56.57
    tributyl phosphate 60.6
    diacetone alcohol 111.89
    N,N-dimethylaniline 68.96
    acrylonitrile 73.92
    aniline 62.96
    1,3-propanediol 133.05
    bromobenzene 46.54
    dibromomethane 100.66
    1,1,2,2-tetrachloroethane 160.5
    2-methyl-cyclohexyl acetate 85.52
    tetrabutyl urea 75.25
    diisobutyl methanol 71.09
    2-phenylethanol 88.01
    styrene 35.61
    dioctyl adipate 79.25
    dimethyl sulfate 74.02
    ethyl butyrate 59.49
    methyl lactate 98.28
    butyl lactate 80.19
    diethyl carbonate 48.88
    propanediol butyl ether 168.29
    triethyl orthoformate 63.28
    p-tert-butyltoluene 54.32
    methyl 4-tert-butylbenzoate 107.78
    morpholine 134.83
    tert-butylamine 134.56
    n-dodecanol 65.44
    dimethoxymethane 90.62
    ethylene carbonate 71.76
    cyrene 120.37
    2-ethoxyethyl acetate 66.19
    2-ethylhexyl acetate 68.97
    1,2,4-trichlorobenzene 86.8
    4-methylpyridine 77.07
    dibutyl ether 69.41
    2,6-dimethyl-4-heptanol 71.09
    DEF 89.69
    dimethyl isosorbide 179.76
    tetrachloroethylene 111.32
    eugenol 112.83
    triacetin 121.99
    span 80 161.28
    1,4-butanediol 73.72
    1,1-dichloroethane 92.5
    2-methyl-1-pentanol 70.04
    methyl formate 65.96
    2-methyl-1-butanol 105.29
    n-decane 28.85
    butyronitrile 62.9
    3,7-dimethyl-1-octanol 107.39
    1-chlorooctane 64.92
    1-chlorotetradecane 32.94
    n-nonane 29.19
    undecane 22.3
    tert-butylcyclohexane 32.62
    cyclooctane 18.7
    cyclopentanol 125.35
    tetrahydropyran 106.3
    tert-amyl methyl ether 107.73
    2,5,8-trioxanonane 179.33
    1-hexene 56.15
    2-isopropoxyethanol 89.0
    2,2,2-trifluoroethanol 67.36
    methyl butyrate 58.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction