Propylene glycol dipalmitate

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  • Identifiers

    CAS number
    33587-20-1

    Molecular formula
    C35H68O4

    SMILES
    CCCCCCCCCCCCCCCC(=O)OCC(C)OC(=O)CCCCCCCCCCCCCCC

    Safety labels

  • Odor profile

    Fragrance
    Waxy 72.57%
    Fatty 69.45%
    Oily 53.43%
    Odorless 35.71%
    Creamy 29.98%
    Sweet 22.95%
    Dairy 22.34%
    Buttery 22.0%
    Milky 20.55%
    Soapy 17.38%

     

    Flavor
    Waxy 59.19%
    Fatty 50.7%
    Oily 48.43%
    Mild 45.3%
    Bland 35.91%
    Faint 32.41%
    Fat 32.2%
    Soapy 31.86%
    Coconut 30.16%
    Creamy 29.63%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    15.1

    pKa est.
    9.2 (weak base)

    Molecular weight
    552.9 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    535°C

    Flash point

    • 244.61 ˚C est.

  • Synonyms

    • Propylene glycol dipalmitate
    • 33587-20-1
    • 1-Methylethane-1,2-diyl dipalmitate
    • H9A347QU31
    • EINECS 251-581-4
    • 1,2-PROPYLENE DIPALMITATE
    • 1,2-PROPANEDIOL DIPALMITATE
    • PALMITIC ACID, PROPYLENE ESTER
    • 1,2-PROPYLENE GLYCOL DIPALMITATE
    • HEXADECANOIC ACID, 1,1'-(1-METHYL-1,2-ETHANEDIYL) ESTER
    • RefChem:869802
    • (+-)-PROPYLENE GLYCOL DIPALMITATE
    • 251-581-4
    • Propane-1,2-diyl dipalmitate
    • 2-hexadecanoyloxypropyl hexadecanoate
    • propane-1,2-diyl dihexadecanoate
    • UNII-H9A347QU31
    • SCHEMBL9619735
    • 1,2-Propyleneglycol dipalmitate
    • SCHEMBL12900882
    • SCHEMBL16338689
    • DTXSID40955222
    • UWTZRBLIYNMYTC-UHFFFAOYSA-N
    • C35H68O4
    • MFCD32661413
    • (+/-)-PROPYLENE GLYCOL DIPALMITATE
    • NS00060451
    • Q27279795
    • 33587-20-1

  • Applications

    Propylene glycol dipalmitate (CAS 33587-20-1) is mainly used as an emollient and skin-conditioning agent in cosmetics and personal care. It also serves as a solvent/vehicle for fragrance oils and cosmetic actives. Additionally, it can function as a lubricating or conditioning agent in hair care and skincare formulations. In some polymer and coatings applications, it may act as a plasticizer or processing aid, and it can serve as a carrier for actives in topical pharmaceutical formulations, subject to regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.29
    methanol 6.96
    isopropanol 5.74
    water 0.14
    ethyl acetate 109.66
    n-propanol 9.82
    acetone 60.16
    n-butanol 10.42
    acetonitrile 25.48
    DMF 109.15
    toluene 49.53
    isobutanol 10.34
    1,4-dioxane 95.0
    methyl acetate 78.23
    THF 252.69
    2-butanone 95.77
    n-pentanol 13.29
    sec-butanol 14.41
    n-hexane 11.0
    ethylene glycol 1.07
    NMP 530.69
    cyclohexane 46.75
    DMSO 126.71
    n-butyl acetate 104.44
    n-octanol 27.58
    chloroform 421.68
    n-propyl acetate 123.51
    acetic acid 41.06
    dichloromethane 455.22
    cyclohexanone 334.42
    propylene glycol 2.86
    isopropyl acetate 104.0
    DMAc 369.84
    2-ethoxyethanol 38.05
    isopentanol 14.81
    n-heptane 9.75
    ethyl formate 47.52
    1,2-dichloroethane 239.69
    n-hexanol 11.84
    2-methoxyethanol 29.92
    isobutyl acetate 76.14
    tetrachloromethane 102.36
    n-pentyl acetate 216.55
    transcutol 254.87
    n-heptanol 21.53
    ethylbenzene 39.48
    MIBK 81.25
    2-propoxyethanol 38.44
    tert-butanol 14.25
    MTBE 52.41
    2-butoxyethanol 69.6
    propionic acid 36.46
    o-xylene 56.37
    formic acid 10.0
    diethyl ether 37.74
    m-xylene 39.24
    p-xylene 64.71
    chlorobenzene 119.5
    dimethyl carbonate 47.76
    n-octane 6.53
    formamide 20.9
    cyclopentanone 330.82
    2-pentanone 89.75
    anisole 76.2
    cyclopentyl methyl ether 154.76
    gamma-butyrolactone 357.52
    1-methoxy-2-propanol 33.88
    pyridine 139.88
    3-pentanone 107.45
    furfural 255.4
    n-dodecane 3.54
    diethylene glycol 13.69
    diisopropyl ether 26.54
    tert-amyl alcohol 30.96
    acetylacetone 169.62
    n-hexadecane 4.35
    acetophenone 137.62
    methyl propionate 91.25
    isopentyl acetate 108.6
    trichloroethylene 512.98
    n-nonanol 31.06
    cyclohexanol 45.28
    benzyl alcohol 35.56
    2-ethylhexanol 21.32
    isooctanol 25.94
    dipropyl ether 56.51
    1,2-dichlorobenzene 187.88
    ethyl lactate 49.07
    propylene carbonate 224.5
    n-methylformamide 37.28
    2-pentanol 12.15
    n-pentane 5.81
    1-propoxy-2-propanol 48.55
    1-methoxy-2-propyl acetate 121.74
    2-(2-methoxypropoxy) propanol 87.72
    mesitylene 32.98
    ε-caprolactone 336.77
    p-cymene 33.94
    epichlorohydrin 315.64
    1,1,1-trichloroethane 335.19
    2-aminoethanol 3.85
    morpholine-4-carbaldehyde 235.46
    sulfolane 682.01
    2,2,4-trimethylpentane 10.09
    2-methyltetrahydrofuran 209.32
    n-hexyl acetate 192.98
    isooctane 3.96
    2-(2-butoxyethoxy)ethanol 95.04
    sec-butyl acetate 106.33
    tert-butyl acetate 156.68
    decalin 20.97
    glycerin 6.93
    diglyme 278.05
    acrylic acid 30.7
    isopropyl myristate 54.7
    n-butyric acid 73.45
    acetyl acetate 111.45
    di(2-ethylhexyl) phthalate 51.76
    ethyl propionate 125.58
    nitromethane 138.9
    1,2-diethoxyethane 132.37
    benzonitrile 65.97
    trioctyl phosphate 34.7
    1-bromopropane 103.43
    gamma-valerolactone 419.68
    n-decanol 18.61
    triethyl phosphate 96.9
    4-methyl-2-pentanol 12.03
    propionitrile 28.74
    vinylene carbonate 176.59
    1,1,2-trichlorotrifluoroethane 223.75
    DMS 117.57
    cumene 30.77
    2-octanol 24.68
    2-hexanone 100.65
    octyl acetate 69.95
    limonene 57.83
    1,2-dimethoxyethane 129.15
    ethyl orthosilicate 90.59
    tributyl phosphate 53.88
    diacetone alcohol 97.08
    N,N-dimethylaniline 65.71
    acrylonitrile 34.99
    aniline 39.77
    1,3-propanediol 7.5
    bromobenzene 160.32
    dibromomethane 244.3
    1,1,2,2-tetrachloroethane 485.15
    2-methyl-cyclohexyl acetate 127.45
    tetrabutyl urea 86.01
    diisobutyl methanol 18.83
    2-phenylethanol 31.96
    styrene 45.66
    dioctyl adipate 109.7
    dimethyl sulfate 153.01
    ethyl butyrate 129.12
    methyl lactate 39.47
    butyl lactate 116.36
    diethyl carbonate 83.72
    propanediol butyl ether 49.18
    triethyl orthoformate 121.81
    p-tert-butyltoluene 30.87
    methyl 4-tert-butylbenzoate 173.07
    morpholine 110.94
    tert-butylamine 11.55
    n-dodecanol 12.3
    dimethoxymethane 62.01
    ethylene carbonate 148.53
    cyrene 115.33
    2-ethoxyethyl acetate 232.59
    2-ethylhexyl acetate 106.18
    1,2,4-trichlorobenzene 245.34
    4-methylpyridine 137.15
    dibutyl ether 84.29
    2,6-dimethyl-4-heptanol 18.83
    DEF 160.37
    dimethyl isosorbide 247.93
    tetrachloroethylene 295.53
    eugenol 111.95
    triacetin 256.74
    span 80 78.38
    1,4-butanediol 5.08
    1,1-dichloroethane 179.13
    2-methyl-1-pentanol 21.33
    methyl formate 35.08
    2-methyl-1-butanol 17.79
    n-decane 8.85
    butyronitrile 30.52
    3,7-dimethyl-1-octanol 31.7
    1-chlorooctane 46.11
    1-chlorotetradecane 12.68
    n-nonane 8.4
    undecane 5.17
    tert-butylcyclohexane 13.72
    cyclooctane 14.64
    cyclopentanol 43.52
    tetrahydropyran 140.37
    tert-amyl methyl ether 71.78
    2,5,8-trioxanonane 149.71
    1-hexene 23.0
    2-isopropoxyethanol 35.92
    2,2,2-trifluoroethanol 37.2
    methyl butyrate 167.92

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction