propyl (2S)-2-hydroxypropanoate

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  • Identifiers

    CAS number
    53651-69-7

    Molecular formula
    C6H12O3

    SMILES
    CCCOC(=O)[C@H](C)O

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Caramellic 79.29%
    Fruity 72.35%
    Sweet 67.77%
    Buttery 62.55%
    Winey 52.31%
    Ethereal 46.75%
    Creamy 45.43%
    Milky 44.4%
    Rummy 40.16%
    Dairy 34.39%

     

    Flavor
    Fruity 82.97%
    Creamy 49.27%
    Sweet 46.57%
    Buttery 39.91%
    Waxy 37.13%
    Fruit 36.5%
    Berry 34.23%
    Butter 33.75%
    Grape 33.47%
    Tropical 33.07%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.8

    pKa est.
    7.77 (neutral)

    Molecular weight
    132.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Boiling point est.
    171°C

    Flash point

    • 68.52 ˚C est.

  • Synonyms

    • propyl (2S)-2-hydroxypropanoate
    • Propyl L-lactate
    • Propyl (S)-(-)-lactate
    • Propyl lactate, L-
    • Propanoic acid, 2-hydroxy-, propyl ester, (2S)-
    • 71C4733FP5
    • (-)-N-PROPYL LACTATE
    • DTXSID3042344
    • PROPYL LACTATE, (-)-
    • EC 611-025-7
    • ILVGAIQLOCKNQA-RXMQYKEDSA-
    • RefChem:869708
    • DTXCID1022344
    • 611-025-7
    • InChI=1/C6H12O3/c1-3-4-9-6(8)5(2)7/h5,7H,3-4H2,1-2H3/t5-/m1/s1
    • 53651-69-7
    • (S)-Propyl 2-hydroxypropanoate
    • (-)-propyl lactate
    • n-Propyl L-lactate
    • (2S)-2-hydroxypropanoic acid propyl ester
    • UNII-71C4733FP5
    • MFCD06658964
    • (s)-n-propyl lactate
    • SCHEMBL6210768
    • ILVGAIQLOCKNQA-YFKPBYRVSA-N
    • 2-hydroxy-propanoic acid propyl ester
    • CS-0238611
    • NS00011492
    • EN300-198251
    • G23883
    • Q27265954
    • 53651-69-7

  • Applications

    Propyl (2S)-2-hydroxypropanoate, also known as propyl lactate, is commonly used as a solvent in fragrance and flavor formulations, cosmetics and personal care products, and household cleaning formulations; it serves as a processing solvent and potential plasticizer for coatings, inks, and certain polymers; in industrial manufacturing it is evaluated as a green solvent and reaction medium for specialty syntheses; and as a chiral intermediate or precursor in organic synthesis for pharmaceutical or agrochemical applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1094.79
    methanol 2048.75
    isopropanol 746.17
    water 46.71
    ethyl acetate 214.24
    n-propanol 699.63
    acetone 547.83
    n-butanol 602.34
    acetonitrile 425.86
    DMF 1054.06
    toluene 76.78
    isobutanol 456.67
    1,4-dioxane 715.04
    methyl acetate 295.33
    THF 585.34
    2-butanone 344.07
    n-pentanol 469.08
    sec-butanol 577.97
    n-hexane 34.08
    ethylene glycol 516.3
    NMP 696.74
    cyclohexane 60.73
    DMSO 1315.17
    n-butyl acetate 300.08
    n-octanol 243.33
    chloroform 624.38
    n-propyl acetate 218.28
    acetic acid 1175.52
    dichloromethane 811.85
    cyclohexanone 453.39
    propylene glycol 424.35
    isopropyl acetate 133.46
    DMAc 748.71
    2-ethoxyethanol 754.16
    isopentanol 430.36
    n-heptane 35.57
    ethyl formate 404.67
    1,2-dichloroethane 444.53
    n-hexanol 362.01
    2-methoxyethanol 1119.15
    isobutyl acetate 129.8
    tetrachloromethane 82.4
    n-pentyl acetate 207.6
    transcutol 1036.95
    n-heptanol 225.39
    ethylbenzene 91.4
    MIBK 156.69
    2-propoxyethanol 545.39
    tert-butanol 728.13
    MTBE 337.44
    2-butoxyethanol 397.3
    propionic acid 491.15
    o-xylene 100.71
    formic acid 921.09
    diethyl ether 233.65
    m-xylene 71.89
    p-xylene 134.48
    chlorobenzene 178.42
    dimethyl carbonate 108.21
    n-octane 21.73
    formamide 831.5
    cyclopentanone 455.42
    2-pentanone 246.95
    anisole 225.87
    cyclopentyl methyl ether 215.03
    gamma-butyrolactone 577.47
    1-methoxy-2-propanol 606.27
    pyridine 378.54
    3-pentanone 165.6
    furfural 716.81
    n-dodecane 22.68
    diethylene glycol 562.28
    diisopropyl ether 64.05
    tert-amyl alcohol 596.16
    acetylacetone 259.08
    n-hexadecane 24.18
    acetophenone 254.22
    methyl propionate 200.13
    isopentyl acetate 263.16
    trichloroethylene 681.85
    n-nonanol 198.63
    cyclohexanol 383.22
    benzyl alcohol 290.0
    2-ethylhexanol 233.6
    isooctanol 169.87
    dipropyl ether 161.19
    1,2-dichlorobenzene 205.07
    ethyl lactate 166.01
    propylene carbonate 356.74
    n-methylformamide 691.37
    2-pentanol 317.89
    n-pentane 39.91
    1-propoxy-2-propanol 381.82
    1-methoxy-2-propyl acetate 219.19
    2-(2-methoxypropoxy) propanol 318.5
    mesitylene 59.56
    ε-caprolactone 433.24
    p-cymene 88.39
    epichlorohydrin 619.58
    1,1,1-trichloroethane 235.57
    2-aminoethanol 660.9
    morpholine-4-carbaldehyde 718.3
    sulfolane 766.07
    2,2,4-trimethylpentane 31.77
    2-methyltetrahydrofuran 425.14
    n-hexyl acetate 289.8
    isooctane 19.35
    2-(2-butoxyethoxy)ethanol 437.84
    sec-butyl acetate 118.52
    tert-butyl acetate 160.59
    decalin 36.13
    glycerin 578.34
    diglyme 741.78
    acrylic acid 507.31
    isopropyl myristate 108.03
    n-butyric acid 539.37
    acetyl acetate 150.31
    di(2-ethylhexyl) phthalate 138.56
    ethyl propionate 155.91
    nitromethane 1023.19
    1,2-diethoxyethane 309.83
    benzonitrile 319.72
    trioctyl phosphate 117.11
    1-bromopropane 223.78
    gamma-valerolactone 691.34
    n-decanol 149.06
    triethyl phosphate 112.85
    4-methyl-2-pentanol 165.55
    propionitrile 325.47
    vinylene carbonate 399.57
    1,1,2-trichlorotrifluoroethane 596.5
    DMS 171.54
    cumene 82.62
    2-octanol 161.7
    2-hexanone 245.85
    octyl acetate 160.48
    limonene 134.07
    1,2-dimethoxyethane 937.4
    ethyl orthosilicate 106.2
    tributyl phosphate 131.39
    diacetone alcohol 278.44
    N,N-dimethylaniline 189.33
    acrylonitrile 462.88
    aniline 185.44
    1,3-propanediol 786.68
    bromobenzene 154.92
    dibromomethane 467.04
    1,1,2,2-tetrachloroethane 579.69
    2-methyl-cyclohexyl acetate 183.61
    tetrabutyl urea 176.61
    diisobutyl methanol 126.09
    2-phenylethanol 239.98
    styrene 111.84
    dioctyl adipate 185.03
    dimethyl sulfate 196.02
    ethyl butyrate 203.06
    methyl lactate 199.82
    butyl lactate 211.52
    diethyl carbonate 146.89
    propanediol butyl ether 401.29
    triethyl orthoformate 147.85
    p-tert-butyltoluene 82.18
    methyl 4-tert-butylbenzoate 234.91
    morpholine 743.05
    tert-butylamine 428.73
    n-dodecanol 117.57
    dimethoxymethane 434.17
    ethylene carbonate 304.47
    cyrene 269.81
    2-ethoxyethyl acetate 242.51
    2-ethylhexyl acetate 190.32
    1,2,4-trichlorobenzene 241.86
    4-methylpyridine 350.43
    dibutyl ether 169.64
    2,6-dimethyl-4-heptanol 126.09
    DEF 400.75
    dimethyl isosorbide 381.19
    tetrachloroethylene 427.04
    eugenol 258.78
    triacetin 250.0
    span 80 286.7
    1,4-butanediol 451.3
    1,1-dichloroethane 323.7
    2-methyl-1-pentanol 387.5
    methyl formate 527.99
    2-methyl-1-butanol 413.82
    n-decane 31.56
    butyronitrile 366.61
    3,7-dimethyl-1-octanol 210.64
    1-chlorooctane 111.81
    1-chlorotetradecane 52.98
    n-nonane 30.82
    undecane 26.05
    tert-butylcyclohexane 36.29
    cyclooctane 20.43
    cyclopentanol 442.58
    tetrahydropyran 432.25
    tert-amyl methyl ether 256.47
    2,5,8-trioxanonane 525.21
    1-hexene 120.11
    2-isopropoxyethanol 414.85
    2,2,2-trifluoroethanol 314.56
    methyl butyrate 285.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction