Propargyl alcohol

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  • Identifiers

    CAS number
    107-19-7

    Molecular formula
    C3H4O

    SMILES
    C#CCO

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Floral 71.2%
    Sweet 24.72%
    Geranium 24.43%
    Rose 22.42%
    Pungent 20.38%
    Sharp 20.23%
    Bitter 19.92%
    Almond 19.37%
    Fresh 19.36%
    Oily 18.5%

     

    Flavor
    Bitter 53.68%
    Odorless 42.88%
    Mild 21.61%
    Formyl 20.14%
    Pungent 20.02%
    Mousy 19.35%
    Very slight 19.09%
    Nitrile 18.92%
    Soy 18.89%
    Sweet-like 18.8%

     

    Odor impact est.
    Medium

    Odor threshold

    • Odor Threshold Low: 0.15 [mmHg]. Odor threshold from CHEMINFO
    • 0.35 mg/cu m

  • Properties

    XLogP3-AA
    -0.4

    pKa est.
    7.41 (neutral)

    Molecular weight
    56.06 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -54 °F (NTP, 1992)
    • -48 to -52 °C
    • -48 - -52 °C
    • -62 °F

    Boiling point

    • 236.5 °F at 760 mmHg (NTP, 1992)
    • 114-115 °C at 760 mm Hg; 100 °C at 490.3 mm Hg; 70 °C at 147.6 mm Hg; 20 °C at 11.6 mm Hg
    • 114 °C
    • 236.5 °F
    • 237 °F

    Flash point

    • 29.0 ˚C est.
    • 91 °F (NTP, 1992)
    • 97 °F
    • 97 °F (36 °C) (Open cup)
    • 33 °C c.c.
    • 97 °F (open cup)
    • (oc) 97 °F

    Solubility expt.

    • Miscible (NIOSH, 2024)
    • Miscible with benzene, chloroform, ethanol, 1,2-dichloroethane, ether, acetone, dioxane, tetrahydrofuran, pyridine; moderately sol in carbon tetrachloride
    • IMMISCIBLE WITH ALIPHATIC HYDROCARBONS
    • Miscible with water
    • Solubility in water: miscible
    • Miscible

  • Synonyms

    • PROPARGYL ALCOHOL
    • Prop-2-yn-1-ol
    • 2-Propyn-1-ol
    • 107-19-7
    • Ethynyl carbinol
    • 2-Propynyl alcohol
    • Ethynylcarbinol
    • 1-Propyn-3-ol
    • Methanol, ethynyl-
    • Propynyl alcohol
    • 2-Propynol
    • 3-Propynol
    • 1-Hydroxy-2-propyne
    • 3-Hydroxy-1-propyne
    • Acetylenylcarbinol
    • Acetylene carbinol
    • Propiolic alcohol
    • Agrisynth PA
    • RCRA waste number P102
    • NSC 8804
    • prop-2-yne-1-ol
    • Prop-2-in-1-ol
    • CCRIS 6781
    • propargylalcohol
    • 1-Propyn-3-yl alcohol
    • HSDB 6054
    • EINECS 203-471-2
    • UNII-E920VF499L
    • BRN 0506003
    • DTXSID5021883
    • CHEBI:28905
    • AI3-24359
    • E920VF499L
    • NSC-8804
    • HC.$.CCH2OH
    • PROPARGYL ALCOHOL [MI]
    • DTXCID301883
    • PROPARGYL ALCOHOL [HSDB]
    • EC 203-471-2
    • 4-01-00-02214 (Beilstein Handbook Reference)
    • Propargyl alcohol [NA1986] [Flammable liquid]
    • 2-propyne-1-ol
    • MFCD00002912
    • NA1986
    • RCRA waste no. P102
    • ethynylmethanol
    • 1Propyn3ol
    • 2Propyn1ol
    • 2Propynyl alcohol
    • prop-2-ynol
    • propyn-3-ol
    • 1-Propyne-3-ol
    • 2-propyn-1 ol
    • prop-2-yn-I-ol
    • prop-1-yn-3-ol
    • ETHYNOL CARBINOL
    • ETHYNYL METHANOL
    • Propargyl alcohol, 99%
    • CARBINOL, ETHYNYL-
    • bmse000363
    • HYDROXYMETHYLACETYLENE
    • WLN: Q2UU1
    • CHEMBL1563026
    • NSC8804
    • Propargyl alcohol (ACGIH:OSHA)
    • Tox21_200976
    • BBL011350
    • STL146440
    • AKOS000118737
    • NA 1986
    • NCGC00091559-01
    • NCGC00091559-02
    • NCGC00258529-01
    • BP-30161
    • CAS-107-19-7
    • NS00003754
    • P0536
    • EN300-19326
    • C05986
    • Q903345
    • F0001-0140

  • Applications

    Propargyl alcohol (CAS 107-19-7) is primarily used as a chemical intermediate to introduce the propargyl (alkynyl) functionality into molecules in organic synthesis, enabling the production of materials with reactive sites for polymers and coatings; it serves as a precursor to propargyl esters and propargyl ethers used as monomers or reactive diluents in epoxy resin systems and UV-curable coatings and adhesives; it is also employed to synthesize glycidyl propargyl ether and related derivatives, supporting epoxy resin technology; it participates in click-chemistry-based surface functionalization and crosslinking in advanced materials and electronics; it can act as an intermediate in pharmaceutical synthesis to access propargyl-containing heterocycles; and it serves as a building block for specialty polymers and photopolymers.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 229.24
    methanol 435.14
    isopropanol 87.14
    water 396.06
    ethyl acetate 29.62
    n-propanol 121.08
    acetone 62.96
    n-butanol 98.44
    acetonitrile 63.56
    DMF 268.58
    toluene 2.57
    isobutanol 59.56
    1,4-dioxane 48.18
    methyl acetate 47.75
    THF 68.5
    2-butanone 37.39
    n-pentanol 48.65
    sec-butanol 57.47
    n-hexane 1.06
    ethylene glycol 253.39
    NMP 137.84
    cyclohexane 2.04
    DMSO 232.57
    n-butyl acetate 19.0
    n-octanol 15.46
    chloroform 23.98
    n-propyl acetate 20.44
    acetic acid 573.93
    dichloromethane 22.36
    cyclohexanone 38.35
    propylene glycol 162.97
    isopropyl acetate 13.63
    DMAc 167.66
    2-ethoxyethanol 143.85
    isopentanol 55.07
    n-heptane 2.73
    ethyl formate 61.35
    1,2-dichloroethane 13.35
    n-hexanol 38.06
    2-methoxyethanol 336.05
    isobutyl acetate 9.7
    tetrachloromethane 9.89
    n-pentyl acetate 13.76
    transcutol 172.6
    n-heptanol 23.61
    ethylbenzene 1.53
    MIBK 15.05
    2-propoxyethanol 90.27
    tert-butanol 72.32
    MTBE 16.01
    2-butoxyethanol 68.15
    propionic acid 190.7
    o-xylene 3.04
    formic acid 852.57
    diethyl ether 17.73
    m-xylene 2.69
    p-xylene 2.2
    chlorobenzene 4.69
    dimethyl carbonate 21.81
    n-octane 0.9
    formamide 773.0
    cyclopentanone 64.09
    2-pentanone 28.01
    anisole 9.07
    cyclopentyl methyl ether 21.9
    gamma-butyrolactone 98.38
    1-methoxy-2-propanol 147.67
    pyridine 34.91
    3-pentanone 17.42
    furfural 108.52
    n-dodecane 0.64
    diethylene glycol 140.92
    diisopropyl ether 4.23
    tert-amyl alcohol 52.84
    acetylacetone 30.58
    n-hexadecane 0.62
    acetophenone 13.9
    methyl propionate 35.23
    isopentyl acetate 12.51
    trichloroethylene 30.76
    n-nonanol 12.44
    cyclohexanol 37.34
    benzyl alcohol 22.19
    2-ethylhexanol 15.88
    isooctanol 15.9
    dipropyl ether 13.02
    1,2-dichlorobenzene 5.15
    ethyl lactate 26.09
    propylene carbonate 38.34
    n-methylformamide 297.89
    2-pentanol 37.52
    n-pentane 2.05
    1-propoxy-2-propanol 55.49
    1-methoxy-2-propyl acetate 22.84
    2-(2-methoxypropoxy) propanol 34.36
    mesitylene 2.07
    ε-caprolactone 44.43
    p-cymene 2.91
    epichlorohydrin 60.53
    1,1,1-trichloroethane 10.8
    2-aminoethanol 295.78
    morpholine-4-carbaldehyde 143.61
    sulfolane 98.06
    2,2,4-trimethylpentane 1.1
    2-methyltetrahydrofuran 35.08
    n-hexyl acetate 14.43
    isooctane 0.82
    2-(2-butoxyethoxy)ethanol 59.42
    sec-butyl acetate 9.22
    tert-butyl acetate 15.11
    decalin 0.73
    glycerin 303.69
    diglyme 105.57
    acrylic acid 230.74
    isopropyl myristate 4.75
    n-butyric acid 146.62
    acetyl acetate 20.84
    di(2-ethylhexyl) phthalate 8.06
    ethyl propionate 14.01
    nitromethane 404.96
    1,2-diethoxyethane 21.77
    benzonitrile 13.48
    trioctyl phosphate 6.88
    1-bromopropane 5.73
    gamma-valerolactone 108.95
    n-decanol 8.59
    triethyl phosphate 9.05
    4-methyl-2-pentanol 16.74
    propionitrile 34.12
    vinylene carbonate 40.29
    1,1,2-trichlorotrifluoroethane 150.17
    DMS 11.99
    cumene 1.79
    2-octanol 10.56
    2-hexanone 16.26
    octyl acetate 8.17
    limonene 4.91
    1,2-dimethoxyethane 82.78
    ethyl orthosilicate 9.17
    tributyl phosphate 7.24
    diacetone alcohol 48.35
    N,N-dimethylaniline 8.72
    acrylonitrile 63.56
    aniline 18.22
    1,3-propanediol 298.89
    bromobenzene 2.73
    dibromomethane 11.73
    1,1,2,2-tetrachloroethane 23.06
    2-methyl-cyclohexyl acetate 11.16
    tetrabutyl urea 10.88
    diisobutyl methanol 8.47
    2-phenylethanol 17.89
    styrene 2.06
    dioctyl adipate 10.07
    dimethyl sulfate 41.43
    ethyl butyrate 17.07
    methyl lactate 58.99
    butyl lactate 21.4
    diethyl carbonate 10.37
    propanediol butyl ether 60.08
    triethyl orthoformate 12.69
    p-tert-butyltoluene 2.96
    methyl 4-tert-butylbenzoate 18.89
    morpholine 92.29
    tert-butylamine 29.24
    n-dodecanol 6.29
    dimethoxymethane 66.21
    ethylene carbonate 29.36
    cyrene 39.05
    2-ethoxyethyl acetate 21.7
    2-ethylhexyl acetate 8.87
    1,2,4-trichlorobenzene 7.07
    4-methylpyridine 19.56
    dibutyl ether 7.77
    2,6-dimethyl-4-heptanol 8.47
    DEF 57.27
    dimethyl isosorbide 40.74
    tetrachloroethylene 26.27
    eugenol 26.92
    triacetin 21.42
    span 80 33.32
    1,4-butanediol 104.38
    1,1-dichloroethane 10.01
    2-methyl-1-pentanol 30.48
    methyl formate 152.9
    2-methyl-1-butanol 55.21
    n-decane 0.97
    butyronitrile 32.93
    3,7-dimethyl-1-octanol 11.6
    1-chlorooctane 2.95
    1-chlorotetradecane 1.29
    n-nonane 0.94
    undecane 0.74
    tert-butylcyclohexane 0.83
    cyclooctane 0.89
    cyclopentanol 55.39
    tetrahydropyran 28.01
    tert-amyl methyl ether 13.79
    2,5,8-trioxanonane 66.92
    1-hexene 3.31
    2-isopropoxyethanol 63.65
    2,2,2-trifluoroethanol 279.01
    methyl butyrate 25.24

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction