Propanoic acid, 2-methoxy-, methyl ester

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  • Identifiers

    CAS number
    17639-76-8

    Molecular formula
    C5H10O3

    SMILES
    CC(C(=O)OC)OC

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 93.77%
    Ethereal 66.78%
    Sweet 59.68%
    Caramellic 47.02%
    Rummy 46.28%
    Buttery 45.08%
    Pineapple 39.66%
    Winey 38.02%
    Nutty 35.89%
    Tropical 35.08%

     

    Flavor
    Fruity 90.49%
    Sweet 60.94%
    Green 46.81%
    Apple 42.59%
    Pineapple 42.13%
    Tropical 40.55%
    Creamy 35.73%
    Fruit 35.41%
    Floral 35.02%
    Berry 34.99%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.4

    pKa est.
    6.05 (neutral)

    Molecular weight
    118.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    127°C

    Flash point

    • 27.78 ˚C est.

  • Synonyms

    • Methyl 2-methoxypropionate
    • Methyl 2-methoxypropanoate
    • Propanoic acid, 2-methoxy-, methyl ester
    • EINECS 241-622-4
    • DTXSID20884980
    • RefChem:176336
    • DTXCID20836146
    • 241-622-4
    • VABBJJOSOCPYIT-UHFFFAOYSA-N
    • 17639-76-8
    • MFCD00151664
    • methyl 2-methoxy-propionate
    • SCHEMBL35974
    • SCHEMBL7361116
    • SCHEMBL8441878
    • AKOS005256968
    • AT18834
    • BS-21815
    • SY047771
    • DB-012955
    • DB-360689
    • CS-0207198
    • NS00053869
    • racemic 2-Methoxy-propionic acid methyl ester
    • 92935-45-0
    • 17639-76-8

  • Applications

    Propanoic acid, 2-methoxy-, methyl ester (methyl 2-methoxypropanoate) serves as a solvent and co-solvent in industrial formulations such as coatings, inks, and cleaning products. It also functions as an organic-synthesis intermediate for the preparation of pharmaceuticals, agrochemicals, and other specialty chemicals. In polymer and plastics chemistry, it can act as a building block for polyester routes and a precursor to higher-value esters or plasticizers. Additionally, it is used as a processing aid in adhesive formulations and related bonding systems. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 763.62
    methanol 1312.01
    isopropanol 500.77
    water 187.03
    ethyl acetate 414.57
    n-propanol 587.96
    acetone 602.46
    n-butanol 395.29
    acetonitrile 939.14
    DMF 903.85
    toluene 86.36
    isobutanol 393.84
    1,4-dioxane 919.59
    methyl acetate 489.89
    THF 626.57
    2-butanone 419.93
    n-pentanol 290.82
    sec-butanol 496.7
    n-hexane 37.36
    ethylene glycol 516.91
    NMP 705.9
    cyclohexane 64.28
    DMSO 1099.33
    n-butyl acetate 140.33
    n-octanol 116.34
    chloroform 1086.2
    n-propyl acetate 192.1
    acetic acid 1529.64
    dichloromethane 1246.43
    cyclohexanone 454.67
    propylene glycol 323.4
    isopropyl acetate 177.72
    DMAc 608.12
    2-ethoxyethanol 759.02
    isopentanol 265.85
    n-heptane 24.65
    ethyl formate 410.73
    1,2-dichloroethane 644.81
    n-hexanol 168.83
    2-methoxyethanol 1174.21
    isobutyl acetate 95.61
    tetrachloromethane 274.58
    n-pentyl acetate 118.14
    transcutol 627.47
    n-heptanol 100.46
    ethylbenzene 75.73
    MIBK 145.42
    2-propoxyethanol 358.86
    tert-butanol 601.18
    MTBE 338.67
    2-butoxyethanol 218.09
    propionic acid 678.13
    o-xylene 106.66
    formic acid 1303.87
    diethyl ether 362.31
    m-xylene 67.52
    p-xylene 114.09
    chlorobenzene 213.29
    dimethyl carbonate 117.53
    n-octane 14.52
    formamide 1361.81
    cyclopentanone 533.0
    2-pentanone 273.4
    anisole 206.51
    cyclopentyl methyl ether 265.77
    gamma-butyrolactone 757.11
    1-methoxy-2-propanol 575.67
    pyridine 482.65
    3-pentanone 233.86
    furfural 743.02
    n-dodecane 11.37
    diethylene glycol 419.3
    diisopropyl ether 86.69
    tert-amyl alcohol 525.39
    acetylacetone 314.39
    n-hexadecane 12.59
    acetophenone 210.33
    methyl propionate 307.63
    isopentyl acetate 127.22
    trichloroethylene 1135.07
    n-nonanol 95.91
    cyclohexanol 341.55
    benzyl alcohol 250.83
    2-ethylhexanol 102.93
    isooctanol 85.6
    dipropyl ether 105.86
    1,2-dichlorobenzene 244.23
    ethyl lactate 141.89
    propylene carbonate 324.91
    n-methylformamide 848.65
    2-pentanol 258.15
    n-pentane 41.18
    1-propoxy-2-propanol 197.28
    1-methoxy-2-propyl acetate 147.27
    2-(2-methoxypropoxy) propanol 179.41
    mesitylene 56.07
    ε-caprolactone 453.7
    p-cymene 60.18
    epichlorohydrin 753.66
    1,1,1-trichloroethane 526.64
    2-aminoethanol 658.53
    morpholine-4-carbaldehyde 721.93
    sulfolane 883.78
    2,2,4-trimethylpentane 34.11
    2-methyltetrahydrofuran 547.05
    n-hexyl acetate 166.94
    isooctane 17.45
    2-(2-butoxyethoxy)ethanol 241.27
    sec-butyl acetate 111.86
    tert-butyl acetate 189.6
    decalin 35.06
    glycerin 540.0
    diglyme 509.39
    acrylic acid 706.13
    isopropyl myristate 62.54
    n-butyric acid 550.99
    acetyl acetate 242.58
    di(2-ethylhexyl) phthalate 71.8
    ethyl propionate 174.04
    nitromethane 1911.16
    1,2-diethoxyethane 197.61
    benzonitrile 292.35
    trioctyl phosphate 54.4
    1-bromopropane 272.15
    gamma-valerolactone 752.22
    n-decanol 69.34
    triethyl phosphate 88.76
    4-methyl-2-pentanol 120.22
    propionitrile 477.51
    vinylene carbonate 344.53
    1,1,2-trichlorotrifluoroethane 749.45
    DMS 153.54
    cumene 68.15
    2-octanol 83.29
    2-hexanone 176.67
    octyl acetate 86.11
    limonene 90.29
    1,2-dimethoxyethane 776.97
    ethyl orthosilicate 83.95
    tributyl phosphate 65.11
    diacetone alcohol 280.31
    N,N-dimethylaniline 163.21
    acrylonitrile 656.82
    aniline 233.25
    1,3-propanediol 712.47
    bromobenzene 188.59
    dibromomethane 729.35
    1,1,2,2-tetrachloroethane 821.24
    2-methyl-cyclohexyl acetate 121.18
    tetrabutyl urea 87.88
    diisobutyl methanol 67.32
    2-phenylethanol 152.64
    styrene 97.46
    dioctyl adipate 99.97
    dimethyl sulfate 242.19
    ethyl butyrate 131.38
    methyl lactate 201.31
    butyl lactate 106.22
    diethyl carbonate 98.78
    propanediol butyl ether 186.84
    triethyl orthoformate 106.91
    p-tert-butyltoluene 57.62
    methyl 4-tert-butylbenzoate 173.21
    morpholine 938.96
    tert-butylamine 364.15
    n-dodecanol 53.19
    dimethoxymethane 403.92
    ethylene carbonate 274.22
    cyrene 229.94
    2-ethoxyethyl acetate 164.87
    2-ethylhexyl acetate 99.99
    1,2,4-trichlorobenzene 310.58
    4-methylpyridine 368.56
    dibutyl ether 96.37
    2,6-dimethyl-4-heptanol 67.32
    DEF 393.1
    dimethyl isosorbide 281.83
    tetrachloroethylene 726.88
    eugenol 186.29
    triacetin 177.3
    span 80 150.05
    1,4-butanediol 350.64
    1,1-dichloroethane 527.31
    2-methyl-1-pentanol 225.4
    methyl formate 606.58
    2-methyl-1-butanol 314.92
    n-decane 19.0
    butyronitrile 398.07
    3,7-dimethyl-1-octanol 98.58
    1-chlorooctane 70.91
    1-chlorotetradecane 29.21
    n-nonane 19.05
    undecane 14.02
    tert-butylcyclohexane 31.99
    cyclooctane 23.08
    cyclopentanol 441.49
    tetrahydropyran 502.58
    tert-amyl methyl ether 266.14
    2,5,8-trioxanonane 321.0
    1-hexene 101.25
    2-isopropoxyethanol 379.69
    2,2,2-trifluoroethanol 654.87
    methyl butyrate 264.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction