Propanoic acid, 2-hydroxy-, 1-methylethyl ester, (2S)-

Overview IFRA Request a quote

  • Identifiers

    CAS number
    63697-00-7

    Molecular formula
    C6H12O3

    SMILES
    C[C@@H](C(=O)OC(C)C)O

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Fruity 93.78%
    Caramellic 65.31%
    Buttery 65.1%
    Sweet 46.22%
    Winey 42.19%
    Creamy 41.88%
    Milky 41.48%
    Ethereal 39.77%
    Dairy 38.31%
    Cheesy 31.27%

     

    Flavor
    Fruity 88.86%
    Creamy 43.34%
    Sweet 43.2%
    Buttery 38.43%
    Tropical 32.71%
    Fruit 32.61%
    Berry 32.22%
    Grape 32.15%
    Butter 30.77%
    Cheese 26.26%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    0.7

    pKa est.
    8.73 (weak base)

    Molecular weight
    132.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    157°C

    Flash point

    • 58.28 ˚C est.

  • Synonyms

    • 63697-00-7
    • Propanoic acid, 2-hydroxy-, 1-methylethyl ester, (2S)-
    • Isopropyl S-(-)-lactate
    • EINECS 264-417-1
    • DTXSID90886638
    • RefChem:869203
    • DTXCID201025962
    • 1-Methylethyl (2S)-2-hydroxypropanoate
    • 264-417-1
    • propan-2-yl (2S)-2-hydroxypropanoate
    • (S)-Isopropyl lactate
    • Isopropyl (S)-2-hydroxypropanoate
    • (S)-isopropyl 2-hydroxypropanoate
    • Isopropyl L-lactate
    • orb3021432
    • SCHEMBL6180156
    • Isopropyl 2-hydroxypropanoate #
    • CHEBI:151025
    • AKOS025295542
    • Isopropyl (S)-(-)-2-hydroxy-propanoate
    • H42847
    • Propanoic acid, 2-hydroxy-, 1-methylethyl ester, (S)-
    • 63697-00-7

  • Applications

    Propanoic acid, 2-hydroxy-, 1-methylethyl ester, (2S)-, commonly known as isopropyl lactate (CAS 63697-00-7), is a renewable solvent widely used as a processing aid in cosmetics and personal care, where it acts as a solvent for active ingredients and fragrances and contributes to formulation stability and texture. It is also employed as a carrier and solvent in perfumery and fragrance formulations, as well as in household products such as cleaners and air fresheners. In industrial manufacturing, it serves as a co-solvent or carrier in coatings, inks, and other formulations, and can function as a plasticizer or processing solvent for certain polymers. Additionally, it is often evaluated as a solvent or co-solvent in pharmaceutical formulations and as a biodegradable component in cleaning and specialty solvent applications, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 341.65
    methanol 683.43
    isopropanol 330.05
    water 25.57
    ethyl acetate 148.71
    n-propanol 305.24
    acetone 347.86
    n-butanol 250.37
    acetonitrile 205.83
    DMF 610.08
    toluene 49.26
    isobutanol 240.02
    1,4-dioxane 390.61
    methyl acetate 185.76
    THF 426.41
    2-butanone 230.06
    n-pentanol 196.01
    sec-butanol 311.91
    n-hexane 35.63
    ethylene glycol 230.16
    NMP 504.08
    cyclohexane 29.1
    DMSO 628.69
    n-butyl acetate 130.3
    n-octanol 144.49
    chloroform 312.71
    n-propyl acetate 107.56
    acetic acid 426.92
    dichloromethane 317.6
    cyclohexanone 294.66
    propylene glycol 249.96
    isopropyl acetate 105.11
    DMAc 508.03
    2-ethoxyethanol 293.21
    isopentanol 204.49
    n-heptane 20.74
    ethyl formate 158.07
    1,2-dichloroethane 206.55
    n-hexanol 199.07
    2-methoxyethanol 490.59
    isobutyl acetate 77.82
    tetrachloromethane 53.26
    n-pentyl acetate 107.23
    transcutol 406.55
    n-heptanol 105.52
    ethylbenzene 51.81
    MIBK 123.48
    2-propoxyethanol 295.57
    tert-butanol 409.52
    MTBE 261.9
    2-butoxyethanol 160.48
    propionic acid 244.32
    o-xylene 66.9
    formic acid 226.92
    diethyl ether 165.79
    m-xylene 55.18
    p-xylene 74.47
    chlorobenzene 97.29
    dimethyl carbonate 64.53
    n-octane 13.51
    formamide 157.68
    cyclopentanone 364.43
    2-pentanone 179.17
    anisole 118.01
    cyclopentyl methyl ether 174.13
    gamma-butyrolactone 398.45
    1-methoxy-2-propanol 351.77
    pyridine 158.05
    3-pentanone 144.39
    furfural 340.62
    n-dodecane 14.1
    diethylene glycol 304.97
    diisopropyl ether 58.69
    tert-amyl alcohol 356.95
    acetylacetone 213.18
    n-hexadecane 15.04
    acetophenone 138.27
    methyl propionate 142.53
    isopentyl acetate 129.56
    trichloroethylene 338.82
    n-nonanol 116.52
    cyclohexanol 221.34
    benzyl alcohol 134.06
    2-ethylhexanol 118.3
    isooctanol 90.65
    dipropyl ether 84.49
    1,2-dichlorobenzene 119.25
    ethyl lactate 104.87
    propylene carbonate 229.81
    n-methylformamide 262.13
    2-pentanol 191.19
    n-pentane 32.66
    1-propoxy-2-propanol 200.39
    1-methoxy-2-propyl acetate 136.53
    2-(2-methoxypropoxy) propanol 164.53
    mesitylene 45.69
    ε-caprolactone 259.83
    p-cymene 49.63
    epichlorohydrin 314.99
    1,1,1-trichloroethane 160.43
    2-aminoethanol 275.73
    morpholine-4-carbaldehyde 427.9
    sulfolane 574.39
    2,2,4-trimethylpentane 28.08
    2-methyltetrahydrofuran 294.36
    n-hexyl acetate 177.36
    isooctane 17.73
    2-(2-butoxyethoxy)ethanol 199.17
    sec-butyl acetate 79.67
    tert-butyl acetate 137.42
    decalin 26.52
    glycerin 335.68
    diglyme 321.37
    acrylic acid 239.75
    isopropyl myristate 70.91
    n-butyric acid 257.31
    acetyl acetate 111.02
    di(2-ethylhexyl) phthalate 82.32
    ethyl propionate 102.08
    nitromethane 422.65
    1,2-diethoxyethane 139.25
    benzonitrile 146.02
    trioctyl phosphate 69.2
    1-bromopropane 123.11
    gamma-valerolactone 408.45
    n-decanol 86.81
    triethyl phosphate 71.32
    4-methyl-2-pentanol 114.82
    propionitrile 164.73
    vinylene carbonate 210.59
    1,1,2-trichlorotrifluoroethane 313.31
    DMS 120.52
    cumene 50.35
    2-octanol 95.08
    2-hexanone 137.16
    octyl acetate 93.92
    limonene 75.75
    1,2-dimethoxyethane 373.65
    ethyl orthosilicate 68.09
    tributyl phosphate 79.29
    diacetone alcohol 212.0
    N,N-dimethylaniline 110.16
    acrylonitrile 206.06
    aniline 100.65
    1,3-propanediol 308.64
    bromobenzene 86.47
    dibromomethane 201.23
    1,1,2,2-tetrachloroethane 322.45
    2-methyl-cyclohexyl acetate 102.07
    tetrabutyl urea 100.69
    diisobutyl methanol 76.07
    2-phenylethanol 121.44
    styrene 55.67
    dioctyl adipate 98.35
    dimethyl sulfate 156.38
    ethyl butyrate 98.08
    methyl lactate 143.08
    butyl lactate 108.73
    diethyl carbonate 72.51
    propanediol butyl ether 208.37
    triethyl orthoformate 80.88
    p-tert-butyltoluene 52.51
    methyl 4-tert-butylbenzoate 147.13
    morpholine 362.53
    tert-butylamine 245.97
    n-dodecanol 66.5
    dimethoxymethane 246.63
    ethylene carbonate 166.71
    cyrene 178.03
    2-ethoxyethyl acetate 122.71
    2-ethylhexyl acetate 98.9
    1,2,4-trichlorobenzene 149.07
    4-methylpyridine 183.23
    dibutyl ether 91.96
    2,6-dimethyl-4-heptanol 76.07
    DEF 252.01
    dimethyl isosorbide 231.4
    tetrachloroethylene 223.65
    eugenol 148.59
    triacetin 153.41
    span 80 151.21
    1,4-butanediol 181.12
    1,1-dichloroethane 184.67
    2-methyl-1-pentanol 173.17
    methyl formate 230.87
    2-methyl-1-butanol 216.37
    n-decane 21.4
    butyronitrile 164.06
    3,7-dimethyl-1-octanol 125.24
    1-chlorooctane 75.18
    1-chlorotetradecane 33.78
    n-nonane 21.9
    undecane 16.73
    tert-butylcyclohexane 30.13
    cyclooctane 14.07
    cyclopentanol 259.62
    tetrahydropyran 254.91
    tert-amyl methyl ether 205.16
    2,5,8-trioxanonane 242.51
    1-hexene 86.0
    2-isopropoxyethanol 197.27
    2,2,2-trifluoroethanol 145.13
    methyl butyrate 153.68

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction