Prohexadione

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  • Identifiers

    CAS number
    88805-35-0

    Molecular formula
    C10H12O5

    SMILES
    CCC(=O)C1C(=O)CC(CC1=O)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Caramellic 59.75%
    Burnt 44.31%
    Sweet 37.05%
    Nutty 34.18%
    Odorless 31.17%
    Buttery 30.92%
    Roasted 30.57%
    Fruity 27.18%
    Popcorn 19.44%
    Creamy 19.07%

     

    Flavor
    Odorless 33.42%
    Very mild 27.63%
    Nutty 24.17%
    Caramel 23.54%
    Fenugreek 21.14%
    Sour 21.1%
    Cotton candy 21.03%
    Extremely sweet 20.91%
    Yeast 20.66%
    Seedy 20.65%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.4

    pKa est.
    5.5 (weak acid)

    Molecular weight
    212.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    413°C

    Flash point

    • 182.0 ˚C est.

  • Synonyms

    • Prohexadione
    • 88805-35-0
    • Prohexadione [ISO]
    • DOCHC
    • 3,5-dioxo-4-propanoylcyclohexane-1-carboxylic acid
    • UNII-4PC163MD7L
    • 3,5-Dioxo-4-propionylcyclohexanecarboxylic acid
    • DOCOC
    • 4PC163MD7L
    • 3,5-dioxo-4-(1-oxopropyl)cyclohexanecarboxylic acid
    • PROHEXADIONE [MI]
    • DTXSID1043966
    • CHEBI:137380
    • 3,5-dioxo-4-propanoylcyclohexanecarboxylic acid
    • Cyclohexanecarboxylic acid, 3,5-dioxo-4-(1-oxopropyl)-
    • RefChem:176183
    • DTXCID9023966
    • 618-212-2
    • 127277-53-6
    • Cyclohexanecarboxylicacid, 3,5-dioxo-4-(1-oxopropyl)-
    • 3,5-dioxo-4-propanoyl-cyclohexanecarboxylic acid
    • SCHEMBL125826
    • orb1741044
    • MSK24023
    • NDA80535
    • MFCD01632344
    • HY-112105A
    • DA-57062
    • CS-0615862
    • NS00003484
    • 88805-35-0

  • Applications

    Prohexadione (CAS 88805-35-0) is a plant growth regulator that inhibits gibberellin biosynthesis. In agricultural and horticultural practice, it is used to regulate vegetative growth and canopy structure. It is commonly applied to cereals (such as wheat and barley) to limit stem elongation and reduce lodging; on tree fruits (apple and pear) and grapevines to suppress shoot growth and improve fruiting and canopy management; in ornamentals and greenhouse crops as a height-control agent to produce compact plants; and in landscape and turf management to help maintain uniform, controlled canopies.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 33.0
    methanol 46.33
    isopropanol 29.86
    water 3.72
    ethyl acetate 11.52
    n-propanol 22.78
    acetone 44.75
    n-butanol 19.62
    acetonitrile 19.72
    DMF 218.41
    toluene 2.38
    isobutanol 15.96
    1,4-dioxane 38.84
    methyl acetate 21.19
    THF 92.6
    2-butanone 29.05
    n-pentanol 15.87
    sec-butanol 23.38
    n-hexane 0.97
    ethylene glycol 20.47
    NMP 141.36
    cyclohexane 0.4
    DMSO 489.42
    n-butyl acetate 12.88
    n-octanol 9.09
    chloroform 19.59
    n-propyl acetate 10.06
    acetic acid 28.73
    dichloromethane 25.48
    cyclohexanone 31.86
    propylene glycol 17.41
    isopropyl acetate 8.59
    DMAc 217.22
    2-ethoxyethanol 53.4
    isopentanol 19.07
    n-heptane 0.34
    ethyl formate 18.64
    1,2-dichloroethane 23.93
    n-hexanol 14.41
    2-methoxyethanol 92.25
    isobutyl acetate 4.72
    tetrachloromethane 3.56
    n-pentyl acetate 7.71
    transcutol 51.13
    n-heptanol 7.79
    ethylbenzene 4.48
    MIBK 14.96
    2-propoxyethanol 47.5
    tert-butanol 42.38
    MTBE 11.98
    2-butoxyethanol 22.03
    propionic acid 21.03
    o-xylene 4.59
    formic acid 45.3
    diethyl ether 11.49
    m-xylene 3.04
    p-xylene 5.65
    chlorobenzene 5.31
    dimethyl carbonate 15.03
    n-octane 0.32
    formamide 67.33
    cyclopentanone 55.16
    2-pentanone 20.69
    anisole 17.38
    cyclopentyl methyl ether 15.69
    gamma-butyrolactone 65.73
    1-methoxy-2-propanol 57.74
    pyridine 19.9
    3-pentanone 15.79
    furfural 62.28
    n-dodecane 0.37
    diethylene glycol 54.38
    diisopropyl ether 2.8
    tert-amyl alcohol 31.12
    acetylacetone 26.32
    n-hexadecane 0.42
    acetophenone 20.7
    methyl propionate 18.46
    isopentyl acetate 12.51
    trichloroethylene 32.35
    n-nonanol 8.53
    cyclohexanol 13.37
    benzyl alcohol 17.85
    2-ethylhexanol 8.22
    isooctanol 6.22
    dipropyl ether 5.79
    1,2-dichlorobenzene 9.02
    ethyl lactate 14.74
    propylene carbonate 28.32
    n-methylformamide 69.26
    2-pentanol 12.57
    n-pentane 0.44
    1-propoxy-2-propanol 27.66
    1-methoxy-2-propyl acetate 20.04
    2-(2-methoxypropoxy) propanol 30.32
    mesitylene 2.6
    ε-caprolactone 30.11
    p-cymene 3.43
    epichlorohydrin 69.04
    1,1,1-trichloroethane 10.96
    2-aminoethanol 27.11
    morpholine-4-carbaldehyde 98.43
    sulfolane 135.58
    2,2,4-trimethylpentane 0.55
    2-methyltetrahydrofuran 34.87
    n-hexyl acetate 13.32
    isooctane 0.37
    2-(2-butoxyethoxy)ethanol 32.18
    sec-butyl acetate 6.36
    tert-butyl acetate 13.45
    decalin 0.92
    glycerin 43.05
    diglyme 57.73
    acrylic acid 21.99
    isopropyl myristate 5.87
    n-butyric acid 19.71
    acetyl acetate 7.8
    di(2-ethylhexyl) phthalate 10.17
    ethyl propionate 12.18
    nitromethane 62.97
    1,2-diethoxyethane 12.96
    benzonitrile 14.75
    trioctyl phosphate 7.61
    1-bromopropane 10.39
    gamma-valerolactone 69.27
    n-decanol 6.39
    triethyl phosphate 12.02
    4-methyl-2-pentanol 8.88
    propionitrile 15.56
    vinylene carbonate 23.93
    1,1,2-trichlorotrifluoroethane 60.13
    DMS 14.2
    cumene 4.11
    2-octanol 5.67
    2-hexanone 15.72
    octyl acetate 7.99
    limonene 4.47
    1,2-dimethoxyethane 79.41
    ethyl orthosilicate 10.03
    tributyl phosphate 8.8
    diacetone alcohol 33.84
    N,N-dimethylaniline 16.73
    acrylonitrile 22.78
    aniline 8.33
    1,3-propanediol 38.62
    bromobenzene 4.25
    dibromomethane 16.33
    1,1,2,2-tetrachloroethane 31.17
    2-methyl-cyclohexyl acetate 11.83
    tetrabutyl urea 15.7
    diisobutyl methanol 5.75
    2-phenylethanol 15.5
    styrene 4.29
    dioctyl adipate 10.78
    dimethyl sulfate 50.48
    ethyl butyrate 10.51
    methyl lactate 25.97
    butyl lactate 12.68
    diethyl carbonate 9.37
    propanediol butyl ether 23.46
    triethyl orthoformate 9.65
    p-tert-butyltoluene 3.29
    methyl 4-tert-butylbenzoate 22.13
    morpholine 52.85
    tert-butylamine 15.7
    n-dodecanol 4.53
    dimethoxymethane 65.64
    ethylene carbonate 17.72
    cyrene 40.1
    2-ethoxyethyl acetate 11.46
    2-ethylhexyl acetate 9.34
    1,2,4-trichlorobenzene 12.11
    4-methylpyridine 22.11
    dibutyl ether 6.55
    2,6-dimethyl-4-heptanol 5.75
    DEF 40.77
    dimethyl isosorbide 48.87
    tetrachloroethylene 17.81
    eugenol 24.03
    triacetin 15.35
    span 80 19.75
    1,4-butanediol 19.9
    1,1-dichloroethane 12.54
    2-methyl-1-pentanol 15.9
    methyl formate 46.46
    2-methyl-1-butanol 17.9
    n-decane 0.62
    butyronitrile 15.6
    3,7-dimethyl-1-octanol 8.74
    1-chlorooctane 3.68
    1-chlorotetradecane 1.51
    n-nonane 0.53
    undecane 0.47
    tert-butylcyclohexane 0.89
    cyclooctane 0.21
    cyclopentanol 19.69
    tetrahydropyran 18.09
    tert-amyl methyl ether 13.05
    2,5,8-trioxanonane 44.72
    1-hexene 3.97
    2-isopropoxyethanol 27.34
    2,2,2-trifluoroethanol 23.82
    methyl butyrate 18.17

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction