Precocene I

Overview IFRA Request a quote

  • Identifiers

    CAS number
    17598-02-6

    Molecular formula
    C12H14O2

    SMILES
    CC1(C=CC2=C(O1)C=C(C=C2)OC)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 60.64%
    Spicy 49.22%
    Phenolic 42.14%
    Herbal 40.04%
    Floral 39.23%
    Woody 34.55%
    Powdery 31.72%
    Tobacco 29.83%
    Anisic 28.2%
    Mint 26.77%

     

    Flavor
    Bitter 50.98%
    Herbal 29.99%
    Camphor 24.01%
    Floral 23.54%
    Woody 22.55%
    Spice 21.52%
    Minty 20.9%
    Ripe apricot 20.56%
    Parsley 20.35%
    Red fruit 20.32%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.3

    pKa est.
    7.67 (neutral)

    Molecular weight
    190.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    288°C

    Flash point

    • 116.06 ˚C est.

  • Synonyms

    • Precocene I
    • 17598-02-6
    • 7-methoxy-2,2-dimethyl-2H-chromene
    • Precocene 1
    • 7-Methoxy-2,2-dimethylchromene
    • PRICOCENE I
    • 6-Demethoxyageratochromene
    • 2,2-Dimethyl-7-methoxy-2H-1-benzopyran
    • 25HLF91DGR
    • DTXSID2037261
    • NSC-318791
    • CHEBI:8368
    • RefChem:868413
    • DTXCID0017261
    • 241-566-0
    • Demethoxyageratochromene
    • 2H-1-Benzopyran, 7-methoxy-2,2-dimethyl-
    • 7-Methoxy-2,2-dimethyl-3-chromene
    • MFCD00006818
    • NSC 318791
    • 2H-1-BENZOPYRAN, 2,2-DIMETHYL-7-METHOXY-
    • 2,2-Dimethyl-2H-chromen-7-yl methyl ether
    • 7-METHOXY-2,2-DIMETHYL-2H-1-BENZOPYRAN
    • EINECS 241-566-0
    • UNII-25HLF91DGR
    • BRN 0133917
    • AI3-36846
    • Prococene I
    • Precocene I, 99%
    • bmse000754
    • SCHEMBL118080
    • CHEMBL451866
    • SCHEMBL29794343
    • 7-methoxy-2,2-dimethyl-chromene
    • NSC318791
    • AKOS006229098
    • SB67357
    • AS-42606
    • SY239904
    • DB-044242
    • NS00025777
    • 2,2-Dimethyl-2H-chromen-7-yl methyl ether #
    • C09017
    • Q27108062
    • InChI=1/C12H14O2/c1-12(2)7-6-9-4-5-10(13-3)8-11(9)14-12/h4-8H,1-3H
    • 17598-02-6

  • Applications

    Precocene I (CAS 17598-02-6) is primarily used as an insect growth regulator (IGR) by inhibiting juvenile hormone synthesis in insects, a mode of action relevant to certain agricultural pest-management programs. It is employed in laboratory and controlled-environment studies to investigate juvenile hormone physiology and insect development, and it may serve as an intermediate or reference compound in the research and development of related agrochemical agents. In analytical and formulation development contexts, it is often used as a reference standard for method development and characterization of insect endocrine assays, subject to regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 146.66
    methanol 175.75
    isopropanol 126.94
    water 2.25
    ethyl acetate 295.67
    n-propanol 132.63
    acetone 298.93
    n-butanol 125.84
    acetonitrile 255.71
    DMF 403.23
    toluene 186.47
    isobutanol 106.92
    1,4-dioxane 810.7
    methyl acetate 335.15
    THF 581.4
    2-butanone 236.17
    n-pentanol 83.32
    sec-butanol 106.02
    n-hexane 21.17
    ethylene glycol 100.27
    NMP 326.54
    cyclohexane 68.27
    DMSO 329.97
    n-butyl acetate 152.68
    n-octanol 78.14
    chloroform 894.28
    n-propyl acetate 127.9
    acetic acid 196.11
    dichloromethane 633.23
    cyclohexanone 313.05
    propylene glycol 111.61
    isopropyl acetate 150.04
    DMAc 543.45
    2-ethoxyethanol 215.42
    isopentanol 122.49
    n-heptane 21.32
    ethyl formate 159.26
    1,2-dichloroethane 368.31
    n-hexanol 128.87
    2-methoxyethanol 358.31
    isobutyl acetate 95.2
    tetrachloromethane 114.77
    n-pentyl acetate 95.98
    transcutol 750.09
    n-heptanol 60.17
    ethylbenzene 81.72
    MIBK 111.84
    2-propoxyethanol 290.54
    tert-butanol 204.34
    MTBE 210.43
    2-butoxyethanol 132.18
    propionic acid 160.02
    o-xylene 113.38
    formic acid 88.92
    diethyl ether 249.64
    m-xylene 115.11
    p-xylene 107.38
    chlorobenzene 224.41
    dimethyl carbonate 189.34
    n-octane 10.5
    formamide 133.17
    cyclopentanone 322.63
    2-pentanone 170.96
    anisole 211.53
    cyclopentyl methyl ether 252.41
    gamma-butyrolactone 386.44
    1-methoxy-2-propanol 252.38
    pyridine 326.11
    3-pentanone 195.19
    furfural 390.02
    n-dodecane 13.06
    diethylene glycol 276.76
    diisopropyl ether 73.98
    tert-amyl alcohol 141.0
    acetylacetone 257.63
    n-hexadecane 14.99
    acetophenone 161.03
    methyl propionate 267.8
    isopentyl acetate 143.55
    trichloroethylene 691.05
    n-nonanol 73.94
    cyclohexanol 168.78
    benzyl alcohol 133.03
    2-ethylhexanol 85.01
    isooctanol 50.83
    dipropyl ether 116.4
    1,2-dichlorobenzene 204.4
    ethyl lactate 91.46
    propylene carbonate 249.54
    n-methylformamide 163.98
    2-pentanol 87.02
    n-pentane 23.07
    1-propoxy-2-propanol 168.21
    1-methoxy-2-propyl acetate 210.33
    2-(2-methoxypropoxy) propanol 174.41
    mesitylene 75.09
    ε-caprolactone 285.04
    p-cymene 57.92
    epichlorohydrin 489.1
    1,1,1-trichloroethane 364.61
    2-aminoethanol 121.9
    morpholine-4-carbaldehyde 503.02
    sulfolane 352.0
    2,2,4-trimethylpentane 18.93
    2-methyltetrahydrofuran 369.16
    n-hexyl acetate 164.14
    isooctane 12.64
    2-(2-butoxyethoxy)ethanol 225.46
    sec-butyl acetate 101.79
    tert-butyl acetate 152.13
    decalin 31.1
    glycerin 170.98
    diglyme 449.86
    acrylic acid 157.97
    isopropyl myristate 75.11
    n-butyric acid 171.41
    acetyl acetate 236.73
    di(2-ethylhexyl) phthalate 79.31
    ethyl propionate 146.84
    nitromethane 388.94
    1,2-diethoxyethane 255.81
    benzonitrile 168.78
    trioctyl phosphate 52.7
    1-bromopropane 176.11
    gamma-valerolactone 471.02
    n-decanol 58.95
    triethyl phosphate 89.48
    4-methyl-2-pentanol 63.24
    propionitrile 172.99
    vinylene carbonate 262.75
    1,1,2-trichlorotrifluoroethane 334.35
    DMS 227.3
    cumene 59.65
    2-octanol 44.31
    2-hexanone 112.56
    octyl acetate 94.25
    limonene 77.86
    1,2-dimethoxyethane 366.07
    ethyl orthosilicate 85.1
    tributyl phosphate 71.34
    diacetone alcohol 162.73
    N,N-dimethylaniline 123.84
    acrylonitrile 207.71
    aniline 194.75
    1,3-propanediol 161.1
    bromobenzene 248.9
    dibromomethane 387.53
    1,1,2,2-tetrachloroethane 587.12
    2-methyl-cyclohexyl acetate 116.29
    tetrabutyl urea 86.32
    diisobutyl methanol 55.97
    2-phenylethanol 139.02
    styrene 103.1
    dioctyl adipate 109.03
    dimethyl sulfate 241.11
    ethyl butyrate 122.17
    methyl lactate 139.92
    butyl lactate 84.56
    diethyl carbonate 114.69
    propanediol butyl ether 135.82
    triethyl orthoformate 108.2
    p-tert-butyltoluene 58.26
    methyl 4-tert-butylbenzoate 139.22
    morpholine 631.35
    tert-butylamine 124.23
    n-dodecanol 49.23
    dimethoxymethane 352.11
    ethylene carbonate 232.39
    cyrene 165.99
    2-ethoxyethyl acetate 185.06
    2-ethylhexyl acetate 124.76
    1,2,4-trichlorobenzene 252.42
    4-methylpyridine 295.98
    dibutyl ether 106.37
    2,6-dimethyl-4-heptanol 55.97
    DEF 237.1
    dimethyl isosorbide 281.93
    tetrachloroethylene 351.07
    eugenol 130.11
    triacetin 215.19
    span 80 136.61
    1,4-butanediol 72.12
    1,1-dichloroethane 340.74
    2-methyl-1-pentanol 88.57
    methyl formate 178.1
    2-methyl-1-butanol 112.92
    n-decane 19.09
    butyronitrile 145.0
    3,7-dimethyl-1-octanol 83.58
    1-chlorooctane 68.35
    1-chlorotetradecane 34.37
    n-nonane 17.58
    undecane 15.5
    tert-butylcyclohexane 27.0
    cyclooctane 23.87
    cyclopentanol 148.23
    tetrahydropyran 433.51
    tert-amyl methyl ether 157.98
    2,5,8-trioxanonane 340.75
    1-hexene 53.7
    2-isopropoxyethanol 149.03
    2,2,2-trifluoroethanol 113.89
    methyl butyrate 155.4

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction