Potassium Hyaluronate

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  • Identifiers

    CAS number
    31799-91-4

    Molecular formula
    C87H74N2O2

    SMILES
    CC=C(C=CCC=CC1C(N(C2=C1C=C(C=C2)C3=CCC(C=C3)C4=CC=CC5=C4OC(=C5C=C)C=C)C6=CC=C7C(C6)C(C8=C7C=CC(=C8)N(C9=CC=C(C=C9)C1=CC=CC=C1)C1=CC=C(C=C1)C1=CC=CC=C1)(C)C)C=C)C(=CC=C)C1=CC2=CC=CC=C2O1

    Safety labels

  • Odor profile

    Fragrance
    Fruity 57.51%
    Floral 51.62%
    Fresh 37.14%
    Green 30.11%
    Spicy 28.78%
    Neroli 25.5%
    Balsamic 22.74%
    Fatty 22.39%
    Tropical 21.98%
    Jasmin 21.88%

     

    Flavor
    Bitter 74.09%
    Nitrile 20.73%
    Oriental 19.4%
    Very strong 18.62%
    Indole 18.25%
    Cedarleaf 18.11%
    Lovage 17.71%
    Heather 17.57%
    Moth ball 17.52%
    Naphthelene 17.49%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    23.9

    pKa est.
    6.05 (neutral)

    Molecular weight
    1179.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    6262°C

    Flash point

    • 349.46 ˚C est.

  • Synonyms

    • 31799-91-4
    • potassium hyaluronate
    • Hyaluronate Potassium
    • RefChem:867843
    • DTXSID401019321
    • RQGAYHMNOBISDK-UHFFFAOYSA-N
    • C87H74N2O2
    • 7-[3-[(1E,4Z,6E,7Z)-7-(1-benzofuran-2-yl)-6-ethylidenedeca-1,4,7,9-tetraenyl]-5-[4-[2,3-bis(ethenyl)-1-benzofuran-7-yl]cyclohexa-1,5-dien-1-yl]-2-ethenyl-2,3-dihydroindol-1-yl]-9,9-dimethyl-N,N-bis(4-phenylphenyl)-8,8a-dihydrofluoren-2-amine
    • 7-[3-[7-(benzofuran-2-yl)-6-ethylidene-deca-1,4,7,9-tetraenyl]-5-[4-(2,3-divinylbenzofuran-7-yl)cyclohexa-1,5-dien-1-yl]-2-vinyl-indolin-1-yl]-9,9-dimethyl-N,N-bis(4-phenylphenyl)-8,8a-dihydrofluoren-2-amine
    • 31799-91-4

  • Applications

    Potassium Hyaluronate (CAS 31799-91-4) is widely used in cosmetics and personal care as a humectant and thickener, helping to retain moisture and control viscosity in serums, creams, and gels. It also serves as an excipient and viscosity modifier in pharmaceutical formulations, including hydrogel and topical products. The polymer is explored for ophthalmic applications as a viscoelastic additive in sterile eye preparations and related formulations. In wound-care, it forms hydrogels and moisture-retentive dressings that support film formation and sustained hydration. In industrial manufacturing and coatings, inks, and adhesives, it acts as a viscosity modifier and conditioning polymer, and in polymers/plastics-related formulations can function as a stabilizer or binder in hydrogel or composite materials.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.1
    methanol 0.13
    isopropanol 0.07
    water 0.0
    ethyl acetate 0.42
    n-propanol 0.14
    acetone 0.3
    n-butanol 0.21
    acetonitrile 0.09
    DMF 0.66
    toluene 0.51
    isobutanol 0.13
    1,4-dioxane 0.64
    methyl acetate 0.33
    THF 1.18
    2-butanone 0.6
    n-pentanol 0.22
    sec-butanol 0.12
    n-hexane 0.02
    ethylene glycol 0.03
    NMP 1.56
    cyclohexane 0.02
    DMSO 0.39
    n-butyl acetate 0.78
    n-octanol 0.26
    chloroform 10.37
    n-propyl acetate 0.52
    acetic acid 0.29
    dichloromethane 5.92
    cyclohexanone 1.47
    propylene glycol 0.04
    isopropyl acetate 0.47
    DMAc 1.66
    2-ethoxyethanol 0.44
    isopentanol 0.25
    n-heptane 0.03
    ethyl formate 0.29
    1,2-dichloroethane 1.52
    n-hexanol 0.22
    2-methoxyethanol 0.39
    isobutyl acetate 0.56
    tetrachloromethane 0.57
    n-pentyl acetate 1.34
    transcutol 2.05
    n-heptanol 0.28
    ethylbenzene 0.35
    MIBK 0.64
    2-propoxyethanol 0.9
    tert-butanol 0.08
    MTBE 0.22
    2-butoxyethanol 1.07
    propionic acid 0.23
    o-xylene 0.29
    formic acid 0.16
    diethyl ether 0.23
    m-xylene 0.33
    p-xylene 0.41
    chlorobenzene 1.36
    dimethyl carbonate 0.43
    n-octane 0.02
    formamide 0.17
    cyclopentanone 1.47
    2-pentanone 0.62
    anisole 0.83
    cyclopentyl methyl ether 0.51
    gamma-butyrolactone 1.34
    1-methoxy-2-propanol 0.39
    pyridine 1.44
    3-pentanone 0.6
    furfural 2.19
    n-dodecane 0.02
    diethylene glycol 0.34
    diisopropyl ether 0.11
    tert-amyl alcohol 0.14
    acetylacetone 0.93
    n-hexadecane 0.02
    acetophenone 1.23
    methyl propionate 0.47
    isopentyl acetate 1.08
    trichloroethylene 7.12
    n-nonanol 0.36
    cyclohexanol 0.19
    benzyl alcohol 0.67
    2-ethylhexanol 0.28
    isooctanol 0.33
    dipropyl ether 0.37
    1,2-dichlorobenzene 1.68
    ethyl lactate 0.41
    propylene carbonate 0.87
    n-methylformamide 0.28
    2-pentanol 0.14
    n-pentane 0.02
    1-propoxy-2-propanol 0.75
    1-methoxy-2-propyl acetate 1.35
    2-(2-methoxypropoxy) propanol 1.69
    mesitylene 0.18
    ε-caprolactone 1.52
    p-cymene 0.3
    epichlorohydrin 2.47
    1,1,1-trichloroethane 1.49
    2-aminoethanol 0.07
    morpholine-4-carbaldehyde 1.7
    sulfolane 1.91
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 0.57
    n-hexyl acetate 1.3
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 1.59
    sec-butyl acetate 0.52
    tert-butyl acetate 0.58
    decalin 0.03
    glycerin 0.13
    diglyme 2.57
    acrylic acid 0.29
    isopropyl myristate 0.63
    n-butyric acid 0.54
    acetyl acetate 0.44
    di(2-ethylhexyl) phthalate 1.14
    ethyl propionate 0.56
    nitromethane 0.57
    1,2-diethoxyethane 1.05
    benzonitrile 0.67
    trioctyl phosphate 0.61
    1-bromopropane 0.73
    gamma-valerolactone 3.33
    n-decanol 0.24
    triethyl phosphate 0.69
    4-methyl-2-pentanol 0.18
    propionitrile 0.21
    vinylene carbonate 1.25
    1,1,2-trichlorotrifluoroethane 3.61
    DMS 0.98
    cumene 0.26
    2-octanol 0.23
    2-hexanone 0.78
    octyl acetate 0.71
    limonene 0.3
    1,2-dimethoxyethane 0.96
    ethyl orthosilicate 0.77
    tributyl phosphate 0.69
    diacetone alcohol 0.65
    N,N-dimethylaniline 0.63
    acrylonitrile 0.32
    aniline 0.51
    1,3-propanediol 0.16
    bromobenzene 1.9
    dibromomethane 2.63
    1,1,2,2-tetrachloroethane 4.79
    2-methyl-cyclohexyl acetate 1.07
    tetrabutyl urea 1.23
    diisobutyl methanol 0.23
    2-phenylethanol 0.9
    styrene 0.38
    dioctyl adipate 1.26
    dimethyl sulfate 0.77
    ethyl butyrate 0.74
    methyl lactate 0.39
    butyl lactate 1.19
    diethyl carbonate 0.53
    propanediol butyl ether 0.69
    triethyl orthoformate 0.94
    p-tert-butyltoluene 0.25
    methyl 4-tert-butylbenzoate 1.96
    morpholine 0.64
    tert-butylamine 0.05
    n-dodecanol 0.17
    dimethoxymethane 0.65
    ethylene carbonate 0.81
    cyrene 1.66
    2-ethoxyethyl acetate 1.96
    2-ethylhexyl acetate 1.04
    1,2,4-trichlorobenzene 2.4
    4-methylpyridine 1.23
    dibutyl ether 0.48
    2,6-dimethyl-4-heptanol 0.23
    DEF 0.77
    dimethyl isosorbide 2.71
    tetrachloroethylene 3.05
    eugenol 2.08
    triacetin 1.48
    span 80 1.46
    1,4-butanediol 0.08
    1,1-dichloroethane 1.12
    2-methyl-1-pentanol 0.32
    methyl formate 0.27
    2-methyl-1-butanol 0.24
    n-decane 0.04
    butyronitrile 0.25
    3,7-dimethyl-1-octanol 0.38
    1-chlorooctane 0.23
    1-chlorotetradecane 0.09
    n-nonane 0.03
    undecane 0.03
    tert-butylcyclohexane 0.03
    cyclooctane 0.01
    cyclopentanol 0.17
    tetrahydropyran 0.47
    tert-amyl methyl ether 0.3
    2,5,8-trioxanonane 2.0
    1-hexene 0.12
    2-isopropoxyethanol 0.45
    2,2,2-trifluoroethanol 0.21
    methyl butyrate 0.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction