Polyglyceryl-2 Triisostearate

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  • Identifiers

    CAS number
    120486-24-0

    Molecular formula
    C60H116O8

    SMILES
    CC(C)CCCCCCCCCCCCCCC(=O)OCC(COCC(COC(=O)CCCCCCCCCCCCCCC(C)C)OC(=O)CCCCCCCCCCCCCCC(C)C)O

  • Odor profile

    Fragrance
    Waxy 71.65%
    Fatty 49.47%
    Odorless 39.82%
    Oily 37.42%
    Alcoholic 20.07%
    Creamy 18.32%
    Sweet 16.19%
    Milky 16.0%
    Woody 15.62%
    Balsamic 15.5%

     

    Flavor
    Mild 41.86%
    Waxy 41.72%
    Bland 41.7%
    Oily 36.79%
    Fatty 36.52%
    Faint 31.7%
    Odorless 28.85%
    Slightly waxy 23.78%
    Fat 22.47%
    Beer 22.22%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    23.6

    pKa est.
    11.9 (strong base)

    Molecular weight
    965.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    693°C

    Flash point

    • 290.83 ˚C est.

  • Synonyms

    • Neorex pgis
    • Salacos 43V
    • Cithrol PG23IS
    • Risorex PGIS23
    • Cosmol 43SV
    • Cosmol 43V
    • 120486-24-0
    • UNII-68DUY2D39A
    • 68DUY2D39A
    • Diglyceryl triisostearate
    • [3-[2,3-bis(16-methylheptadecanoyloxy)propoxy]-2-hydroxypropyl] 16-methylheptadecanoate
    • OWRMXHRUFYLLQP-UHFFFAOYSA-N
    • Q27264246

  • Applications

    Polyglyceryl-2 Triisostearate (CAS 120486-24-0) is a non-ionic ester commonly used as an emollient and surfactant in cosmetic and personal-care formulations, enhancing skin and hair conditioning, spreadability, and the stability of oil-in-water emulsions. In perfumery and fragrance-related applications, it can serve as a fragrance solubilizer and carrier, promoting even distribution of scent ingredients. It is also employed in household and cleaning products as a mild surfactant and slip agent that supports effective cleaning with acceptable skin feel. In coatings and inks, Polyglyceryl-2 Triisostearate acts as a dispersant/emulsifier to improve pigment stability and formulation homogeneity. In pharmaceutical topical formulations, it may be used as an excipient and solubilizer to aid the delivery of actives and fragrances in a gentle, emollient base.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.96
    methanol 9.56
    isopropanol 8.28
    water 0.17
    ethyl acetate 87.17
    n-propanol 13.91
    acetone 64.95
    n-butanol 12.52
    acetonitrile 19.86
    DMF 118.36
    toluene 39.35
    isobutanol 12.34
    1,4-dioxane 70.65
    methyl acetate 69.57
    THF 188.24
    2-butanone 81.77
    n-pentanol 15.23
    sec-butanol 17.23
    n-hexane 4.75
    ethylene glycol 1.85
    NMP 419.97
    cyclohexane 10.2
    DMSO 127.82
    n-butyl acetate 57.03
    n-octanol 20.94
    chloroform 250.17
    n-propyl acetate 75.04
    acetic acid 78.92
    dichloromethane 230.62
    cyclohexanone 187.87
    propylene glycol 5.55
    isopropyl acetate 74.96
    DMAc 319.59
    2-ethoxyethanol 43.78
    isopentanol 13.73
    n-heptane 4.1
    ethyl formate 44.15
    1,2-dichloroethane 116.85
    n-hexanol 11.43
    2-methoxyethanol 38.52
    isobutyl acetate 46.59
    tetrachloromethane 51.96
    n-pentyl acetate 111.47
    transcutol 212.8
    n-heptanol 16.75
    ethylbenzene 25.55
    MIBK 51.89
    2-propoxyethanol 42.37
    tert-butanol 14.67
    MTBE 38.65
    2-butoxyethanol 59.2
    propionic acid 48.72
    o-xylene 40.94
    formic acid 18.68
    diethyl ether 27.44
    m-xylene 30.02
    p-xylene 36.28
    chlorobenzene 69.6
    dimethyl carbonate 58.46
    n-octane 2.76
    formamide 29.65
    cyclopentanone 238.23
    2-pentanone 71.85
    anisole 50.06
    cyclopentyl methyl ether 104.41
    gamma-butyrolactone 298.57
    1-methoxy-2-propanol 43.37
    pyridine 98.88
    3-pentanone 80.75
    furfural 200.67
    n-dodecane 1.54
    diethylene glycol 16.56
    diisopropyl ether 16.18
    tert-amyl alcohol 28.25
    acetylacetone 140.64
    n-hexadecane 1.84
    acetophenone 90.44
    methyl propionate 91.91
    isopentyl acetate 59.25
    trichloroethylene 304.7
    n-nonanol 22.02
    cyclohexanol 32.87
    benzyl alcohol 32.68
    2-ethylhexanol 14.3
    isooctanol 17.86
    dipropyl ether 31.72
    1,2-dichlorobenzene 95.37
    ethyl lactate 47.65
    propylene carbonate 176.8
    n-methylformamide 47.75
    2-pentanol 13.67
    n-pentane 3.11
    1-propoxy-2-propanol 47.53
    1-methoxy-2-propyl acetate 89.1
    2-(2-methoxypropoxy) propanol 69.69
    mesitylene 20.57
    ε-caprolactone 226.16
    p-cymene 19.61
    epichlorohydrin 229.53
    1,1,1-trichloroethane 180.96
    2-aminoethanol 6.39
    morpholine-4-carbaldehyde 206.32
    sulfolane 518.06
    2,2,4-trimethylpentane 5.01
    2-methyltetrahydrofuran 125.7
    n-hexyl acetate 102.17
    isooctane 2.05
    2-(2-butoxyethoxy)ethanol 77.35
    sec-butyl acetate 65.7
    tert-butyl acetate 103.68
    decalin 7.93
    glycerin 11.39
    diglyme 183.91
    acrylic acid 44.98
    isopropyl myristate 29.13
    n-butyric acid 78.08
    acetyl acetate 87.48
    di(2-ethylhexyl) phthalate 34.59
    ethyl propionate 80.51
    nitromethane 171.94
    1,2-diethoxyethane 72.84
    benzonitrile 40.23
    trioctyl phosphate 23.21
    1-bromopropane 55.29
    gamma-valerolactone 324.79
    n-decanol 12.76
    triethyl phosphate 54.78
    4-methyl-2-pentanol 10.74
    propionitrile 22.27
    vinylene carbonate 142.03
    1,1,2-trichlorotrifluoroethane 208.53
    DMS 85.71
    cumene 19.29
    2-octanol 16.72
    2-hexanone 66.9
    octyl acetate 41.22
    limonene 31.71
    1,2-dimethoxyethane 88.56
    ethyl orthosilicate 49.44
    tributyl phosphate 33.04
    diacetone alcohol 83.03
    N,N-dimethylaniline 45.47
    acrylonitrile 30.32
    aniline 36.61
    1,3-propanediol 10.93
    bromobenzene 85.6
    dibromomethane 124.7
    1,1,2,2-tetrachloroethane 288.34
    2-methyl-cyclohexyl acetate 65.85
    tetrabutyl urea 48.98
    diisobutyl methanol 11.12
    2-phenylethanol 26.14
    styrene 27.42
    dioctyl adipate 58.02
    dimethyl sulfate 165.42
    ethyl butyrate 70.19
    methyl lactate 52.94
    butyl lactate 85.36
    diethyl carbonate 46.91
    propanediol butyl ether 50.26
    triethyl orthoformate 68.45
    p-tert-butyltoluene 19.9
    methyl 4-tert-butylbenzoate 122.63
    morpholine 92.95
    tert-butylamine 9.41
    n-dodecanol 8.06
    dimethoxymethane 70.07
    ethylene carbonate 115.76
    cyrene 98.43
    2-ethoxyethyl acetate 148.22
    2-ethylhexyl acetate 53.8
    1,2,4-trichlorobenzene 135.98
    4-methylpyridine 90.5
    dibutyl ether 36.97
    2,6-dimethyl-4-heptanol 11.12
    DEF 116.92
    dimethyl isosorbide 158.14
    tetrachloroethylene 165.6
    eugenol 77.27
    triacetin 177.45
    span 80 58.98
    1,4-butanediol 6.85
    1,1-dichloroethane 108.16
    2-methyl-1-pentanol 18.54
    methyl formate 49.42
    2-methyl-1-butanol 17.57
    n-decane 3.92
    butyronitrile 20.19
    3,7-dimethyl-1-octanol 20.91
    1-chlorooctane 23.12
    1-chlorotetradecane 6.25
    n-nonane 3.62
    undecane 2.26
    tert-butylcyclohexane 6.11
    cyclooctane 4.74
    cyclopentanol 39.76
    tetrahydropyran 81.88
    tert-amyl methyl ether 52.89
    2,5,8-trioxanonane 99.83
    1-hexene 14.07
    2-isopropoxyethanol 38.99
    2,2,2-trifluoroethanol 54.62
    methyl butyrate 103.34

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction